--- Log opened Wed May 02 00:00:05 2018 00:12 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 00:30 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 260 seconds] 00:38 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 00:44 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 00:45 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: *exhales sharply*] 00:49 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 01:20 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-otszaplqhwbgdopv] has quit [Ping timeout: 245 seconds] 01:20 -!- kershaw[m] [kershawmat@gateway/shell/matrix.org/x-fciqucdzzmyfgowq] has quit [Ping timeout: 245 seconds] 01:23 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-xctayfpynmybvjow] has joined ##hplusroadmap 01:23 -!- kershaw[m] [kershawmat@gateway/shell/matrix.org/x-vgivknbwkeiwxqlg] has joined ##hplusroadmap 02:14 -!- red-001 [red@gateway/shell/elitebnc/x-dawmisqgompsypnr] has quit [Ping timeout: 264 seconds] 02:41 -!- red-001 [red@gateway/shell/elitebnc/x-xaznuhrrwjgufjna] has joined ##hplusroadmap 04:37 < fltrz> fenn, do we know the isotopic composition of mantle-carbon? i.e. are any isotopes of carbon created by fission in the mantle? 04:38 < fltrz> and at what rate is carbon-14(dioxide) formed cosmic irradiation of nitrogen? 04:51 < fltrz> the deep ocean contains most carbon in the form of carbonates. this picture does not yet show mantle carbon... 04:51 < fltrz> https://en.wikipedia.org/wiki/Radiocarbon_dating#Carbon_exchange_reservoir 04:58 < fltrz> consider a cubical igneous rock stone in a river, and a homogenous concentration of dissolved CO2 in the water, then subdivide the cube in voxels 04:59 < fltrz> the voxel in the middle of a face of the cube has only one surface exposed, those on the ribs have 2 surfaces exposed and those on the corners have 3 exposed 05:00 < fltrz> so the corners will react faster with CO2, becoming salt, which dissociates into ions in water spontaneously, so the voxels in corners dissapear at a rate of 3x, the ribs at a rate of 2x, and the faces at x 05:01 < fltrz> so even without mechanical abrasion we can predict round cobblestones from a strictly chemical perspective 05:02 < fltrz> the highest curvature spots of the rock dissolve faster than the lowest curvature ones 05:02 < fltrz> correction, convert faster into salts 05:04 < fltrz> so without lifeforms, carbon accumulates to the seas. do photosynthetic lifeforms get their carbon strictly from CO2 or also from carbonates? 05:05 < fltrz> when I asked " are any isotopes of carbon created by fission in the mantle?" I meant to write radioactive decay instead of fission 05:07 -!- gwillen [~gwillen@unaffiliated/gwillen] has quit [Remote host closed the connection] 05:15 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 05:27 -!- jtimon [~quassel@142.29.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 05:35 < streety> http://www.bbc.com/news/technology-43973588 bbc article on Aaron Traywick death. Interesting quote from Josiah Zayner at the end, not sure why they included it 05:55 < fltrz> I think Zayner's quote is quite apt tbh 05:56 < fltrz> why should we blindly trust people on their word? 06:23 < kanzure> sooo i guess it's probably fine to say this now, but uh, i had hired his team away from him a few months ago 06:23 < kanzure> unless his death is another publicity stunt 06:23 < JayDugger> Hm. 06:28 < JayDugger> I'll point out that your new hires were available, and probably wouldn't have been if things had been going well. 06:29 < JayDugger> Typing that seems trite, though. 06:29 < kanzure> yes they all knew he was an idiot 06:29 < JayDugger> An uncomfortable coincidence, then. 06:30 < JayDugger> At most. 06:30 < kanzure> i don't care 06:36 < kanzure> https://gizmodo.com/artificial-genome-scientists-want-to-build-human-cells-1825693446 06:49 < streety> what are they working on with you now? 06:49 < streety> my surprise was more that that the BBC would publish what seems to be a reference/support for a 9/11 conspiracy theory 06:53 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 06:55 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has joined ##hplusroadmap 07:04 < kanzure> streety: they are among us. i am having them finish up that polymerase paper that we were drafting. 07:04 < kanzure> http://www.bioworld.com/content/cellectis-inks-deal-wyss-church-puts-talens-heart-cell-recoding-effort-0 09:07 < fenn> zayner's quote "believing jet fuel can melt steel beams" is implicitly challenging the NIST expert testimony about 9/11, and pulling in a whole world of associations about deep state corruption and government agents literally attacking the american populace 09:07 < fenn> it's a distraction from the main point that you need evidence in order to do science 09:07 < fenn> "look at me, i'm a crazy person! loooloolooolooo" 09:08 < fenn> is the net effect for the average reader 09:09 < fenn> meant to paste this yesterday during IP conversation http://www.foxnews.com/tech/2018/04/24/monkey-cant-own-copyright-to-its-famous-selfie-appeals-court-rules.amp.html 09:13 < fenn> i've never heard of "cellectis" - since when do they own TALENs? 09:18 < fenn> i guess they are just supplying the production capacity? 09:18 < fenn> in exchange they get virgin T-cells for their cancer therapy 09:20 < fenn> man it's so nice having a clean desk 09:21 < fenn> if only i could do something about all these tabs 09:41 -!- strages [uid11297@gateway/web/irccloud.com/x-tblzrnweqvcqkefw] has quit [Quit: Connection closed for inactivity] 09:57 < fenn> falcon 9 fairing returns to earth https://scontent-arn2-1.cdninstagram.com/vp/f40d1348fbf435a7c4c6dd3fba5505fc/5B60FF52/t51.2885-15/e35/31070327_164427757566288_2666001116772171776_n.jpg 10:21 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 10:23 < juri_> Jet fuel might not be able to melt steel beams, but i'm betting that plane was still loaded with mind control chemtrail juice, and who knows what temperature that burns at! 10:24 < juri_> (with apologies to XKCD) 11:01 -!- gwillen [~gwillen@unaffiliated/gwillen] has joined ##hplusroadmap 11:04 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 256 seconds] 11:25 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has quit [Ping timeout: 276 seconds] 11:31 < kanzure> https://cosmosmagazine.com/biology/life-2-0-inside-the-synthetic-biology-revolution 11:35 -!- sachy [~sachy@78.108.102.220] has joined ##hplusroadmap 12:06 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has joined ##hplusroadmap 12:06 < lewl> Haho 12:09 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has quit [Remote host closed the connection] 12:12 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has joined ##hplusroadmap 12:19 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has quit [Remote host closed the connection] 12:22 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has joined ##hplusroadmap 12:24 -!- lewl [~Mutter@catv-212-96-55-21.catv.broadband.hu] has quit [Remote host closed the connection] 13:15 < nmz787> also, an idea I had was about insurance for designer babies... health insurance for them (is GMO a pre-condition that means they won't be covered???), and also insurance for the parents should their GMO die (and thus moral outrage ensues from the public, legal suits come about, etc) 13:15 < nmz787> idea/concern 13:17 < kanzure> not sure that life insurance is a good business to be in 13:17 < kanzure> or health insurance for that matter 13:17 < fenn> for dalmations at least genetic engineering is considered a drug, so the company doing the engineering would be liable and thus presumably have liability insurance 13:18 < fenn> pretty sure moral outrage is guaranteed regardless the health of the baby 13:41 < kanzure> how to handle liability is a big stinking open question 13:41 < kanzure> .wik FOXO4-dri 13:41 < yoleaux> "Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene. It is located on the long arm of the X chromosome from base pair 71,096,148 to 71,103,533." — https://en.wikipedia.org/wiki/FOXO4 13:51 < kanzure> forkhead 13:54 < nmz787> kanzure: I wasn't talking about life insurance, more like insuring the parents against 'wrongdoing' because "an GMO" 13:54 < nmz787> "any GMO" 13:56 < kanzure> not sure this is insurable; where would we find the underwriter? 13:56 < kanzure> insurance is a big network of underwriters that you send out the applications to 13:56 < kanzure> actually it's all xml 13:56 < kanzure> it's really weird 14:04 < kanzure> efcavitch says this is the dnascript/ybert patent https://patentscope.wipo.int/search/en/detail.jsf?docId=AU194375247&recNum=10&office=&queryString=FP%3A%28DNA+Script%29&prevFilter=&sortOption=Pub+Date+Desc&maxRec=27 14:04 < kanzure> "A modified nucleotide, intended for the synthesis of long chain nucleic acids by enzymatic processes, comprising a "natural" nitrogenous base or a natural nitrogenous base analogue, a ribose or deoxyribose carbohydrate, and at least one phosphate group, characterized in that said nucleotide comprises at least one R group, termed the modifier group, carried by said nitrogenous base or ... 14:04 < kanzure> ...analogue and/or by the oxygen in position 3' of the ribose or deoxyribose molecule, making it possible to block the polymerization of said nucleotide and/or to allow the interaction of said nucleotide with another molecule, such as a protein, during the nucleic acid synthesis, R comprising at least one functional terminal group." 14:05 < kanzure> during his presentation yesterday he said it was all natural unmodified nucleotides though.. 14:07 < kanzure> their patent applications describe a complex biotin capture pullout purification at every cycle with PCR every few cycles 14:16 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has joined ##hplusroadmap 14:31 < kanzure> this seems like a misleading name https://github.com/kubeless/kubeless 15:19 < kanzure> "@DNAScript, a startup that aims to develop a printer capable of synthesizing high-quality DNA. " 15:19 < kanzure> hmm they want desktop printer thing. 15:22 < juri_> didn't we go down that road? 15:38 -!- sachy [~sachy@78.108.102.220] has quit [Quit: Leaving.] 15:42 < kanzure> tdt? 15:42 < kanzure> not specifically.. we haven't figured out a good tdt stepwise protocol thing. 15:47 < fenn> a desktop dna printer 15:49 < fenn> what's the tl;dr in english (not patentspeak) 16:11 -!- void_3301 [~quassel@ec2-18-219-8-108.us-east-2.compute.amazonaws.com] has joined ##hplusroadmap 16:16 -!- Netsplit *.net <-> *.split quits: void3301, juul 16:17 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 16:19 -!- pepesza- [~pepesza@185.83.218.228] has quit [Ping timeout: 260 seconds] 16:21 -!- pepesza [~pepesza@185.83.218.228] has joined ##hplusroadmap 16:23 -!- Netsplit over, joins: juul 16:25 -!- ebowden [~ebowden@128.250.0.209] has quit [Ping timeout: 248 seconds] 16:26 -!- ebowden [~ebowden@128.250.0.209] has joined ##hplusroadmap 16:31 -!- ebowden [~ebowden@128.250.0.209] has quit [Ping timeout: 256 seconds] 17:13 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 17:18 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 268 seconds] 17:20 -!- lewl [~l_wl@20014C4E19C01A4A5D5086F8474FA355.dsl.pool.telekom.hu] has joined ##hplusroadmap 17:58 -!- lewl [~l_wl@20014C4E19C01A4A5D5086F8474FA355.dsl.pool.telekom.hu] has quit [Ping timeout: 265 seconds] 18:06 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 18:07 < kanzure> yeah i don't actually know what dnascript's method is, yet 18:08 < kanzure> i think it's tdt + stepwise protect/deprotect 18:18 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has quit [Ping timeout: 248 seconds] 18:24 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 18:49 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 264 seconds] 18:55 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 19:05 -!- ebowden [~ebowden@128.250.0.209] has joined ##hplusroadmap 19:57 < kanzure> hmph 19:58 < fenn> bah humbug 19:59 < kanzure> yeah.. 19:59 < kanzure> i am the spirit of xmas future and i'm here to tell you that you guys need to really get going on your shit 20:02 < kanzure> music! https://www.youtube.com/watch?v=pNSAbDeTKMM 20:02 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: *exhales sharply*] 20:07 -!- duper [~super@ns1.blackcatz.org] has quit [Remote host closed the connection] 20:49 < juri_> always more to do... 21:14 -!- jtimon [~quassel@142.29.134.37.dynamic.jazztel.es] has quit [Ping timeout: 264 seconds] 21:37 -!- preview [~quassel@2407:7000:842d:4000::3] has joined ##hplusroadmap 21:38 -!- lewl__ [~l_wl_@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 21:39 -!- lewl_ [~l_wl_@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Read error: Connection reset by peer] 22:26 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Ping timeout: 264 seconds] 22:57 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 23:14 -!- Douhet [~Douhet@unaffiliated/douhet] has joined ##hplusroadmap --- Log closed Thu May 03 00:00:06 2018