--- Log opened Sat May 12 00:00:15 2018 00:57 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 01:08 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 02:12 -!- ebowden_ [~ebowden@128.250.0.209] has quit [Ping timeout: 255 seconds] 02:19 -!- aeiousom1thing [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 02:22 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 256 seconds] 02:37 -!- ebowden [~ebowden@128.250.0.209] has joined ##hplusroadmap 02:57 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 02:58 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 256 seconds] 03:17 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has joined ##hplusroadmap 04:52 -!- lewl [~lewl@ool-4574ba66.dyn.optonline.net] has joined ##hplusroadmap 04:52 < kanzure> "Each therapy is planned to consist of an inactive genetic payload (to be integrated into a patient only once) and a proprietary inductor to activate the rejuvenating genes (to be applied at regular intervals). For animal therapy, the genetic payload portion will be sold to licensed veterinarians" 04:52 < kanzure> whatever. 04:53 < kanzure> "Market availability of pets with OSKM genes inducible by doxycycline" 04:53 < kanzure> ".. to be collaborating with Dr. Vadim Gladyshev and his lab at the Harvard Medical School on designing experiments aimed at assessing the impact of partial reprogramming on the methylation clock and other rejuvenation metrics in vivo and in vitro in the transgenic OSKM-WT mouse strain. Dr. Gladyshev and his lab members have extensive experience with transgenic OSKM naked mole rat and murine ... 04:54 < kanzure> ...models, as well as with murine methylation clock – in particular, how it is affected by various lifespan-extending interventions." 04:54 < kanzure> ( http://www.youthereum.io ) 04:55 < kanzure> "Others are looking for drugs that could activate latent yamanka factors in humans or otherwise epigentically turn on the program" 05:45 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has joined ##hplusroadmap 05:59 -!- jqtrde [~jqtrde@66-90-137-217.dyn.grandenetworks.net] has quit [Ping timeout: 264 seconds] 06:21 -!- Netsplit *.net <-> *.split quits: formsdothis[m] 06:25 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-niexbiyjufubrgyj] has quit [Ping timeout: 255 seconds] 06:25 -!- ebowden [~ebowden@128.250.0.209] has quit [Read error: Connection reset by peer] 06:26 -!- kershaw[m] [kershawmat@gateway/shell/matrix.org/x-aycaxkczsbfffsvu] has quit [Ping timeout: 256 seconds] 06:27 -!- ebowden_ [~ebowden@128.250.0.209] has joined ##hplusroadmap 06:42 -!- formsdothis[m] [formsdothi@gateway/shell/matrix.org/x-wintqfpvogzvlzeb] has joined ##hplusroadmap 07:00 -!- kershaw[m] [kershawmat@gateway/shell/matrix.org/x-crasamuwbfnvcqwk] has joined ##hplusroadmap 07:00 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-rbyfzxbkrpdzcruz] has joined ##hplusroadmap 07:03 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 07:03 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 07:44 -!- lewl [~lewl@ool-4574ba66.dyn.optonline.net] has quit [Remote host closed the connection] 07:48 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 08:13 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has quit [Ping timeout: 260 seconds] 08:14 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 08:14 -!- DataPacRat [~dan@104.254.90.170] has joined ##hplusroadmap 08:23 < kanzure> https://thegradient.pub/semantic-segmentation/ 08:35 < kanzure> "Alpine ibex males grow large horns at no survival cost for most of their lifetime" https://link.springer.com/article/10.1007%2Fs00442-013-2700-1 08:50 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 08:51 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 08:53 -!- snowtires [~user9@cablepool6-15.stoweaccess.com] has joined ##hplusroadmap 08:57 -!- snowtires [~user9@cablepool6-15.stoweaccess.com] has quit [Client Quit] 09:39 < streety> Does anyone know of any cheaper providers to downloading data from the cloud via mailed HDDs than Amazon? 09:39 < streety> I think Google or Microsoft offer a similar service but last time I checked the price was about the same 10:00 -!- DataPacRat [~dan@104.254.90.170] has quit [Ping timeout: 264 seconds] 10:19 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has joined ##hplusroadmap 10:19 < kanzure> cost per semi-truck of data is cheapest at amazon for now i think 10:50 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has quit [Ping timeout: 256 seconds] 11:06 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has joined ##hplusroadmap 11:22 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:6850:6f95:f9ee:9636] has joined ##hplusroadmap 11:57 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has joined ##hplusroadmap 12:10 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has quit [Ping timeout: 276 seconds] 12:37 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 12:46 < nmz787> hmm, clones are less moral than engineered post-humans? Because you knowingly allowed flaws to remain, while engineered beings may be flawed, but that should be accidental rather than known at the time of conception. 12:47 -!- strages [uid11297@gateway/web/irccloud.com/x-nvgfavwwcpihrqse] has quit [Quit: Connection closed for inactivity] 13:17 < kanzure> the pro-clone argument is that you already know the phenotype; at best you have made an argument for engineered clones rather than natty clones. 13:25 < nmz787> if the DNA ! == then it isn't a clone 13:25 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 13:26 < kanzure> ehhhhh yeah but non-clone usually means 50/50 parent contribution 13:26 < kanzure> yashgaroth what's the appropriate terminology here 13:26 -!- aeiousom1thing [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 260 seconds] 13:28 < streety> okay, thanks. I guess I'll just stick to being patient 13:29 < yashgaroth> no one's settled on a term since a. it's biology and b. even identical twins have tiny variations, or different cells in the same body, so it's tough 13:30 < yashgaroth> and the phenotype isn't gonna be 100% identical anyway since a lot of that is epigenetic 13:31 < nmz787> phenoclone? 13:31 < yashgaroth> parthenoclone, idk 13:33 < kanzure> parthenoclone is kinda close yeah 13:33 < nmz787> so something I read a few days ago said that if we extrapolated gestation time of primates to humans, based on cranial size (I think)... that human gestation should be double or triple what it is today 13:33 < kanzure> maybe just e-clone for edited 13:34 < yashgaroth> mhm we have super-early gestation since the head won't fit through the cervix otherwise 13:35 < kanzure> we should go find mutations that enhance premie survivability 13:42 -!- jqtrde [~jqtrde@12.227.183.66] has joined ##hplusroadmap 13:46 -!- jb55 [~jb55@2605:8d80:4c4:680f:a2af:bdff:fef0:c102] has joined ##hplusroadmap 13:48 < kanzure> jqtrde: be greeted 13:49 < jqtrde> hi @kanzure - sorry i keep popping in and out :| 13:49 < nmz787> kanzure: I was thinking more of making sure the baby gestates longer, and I guess fix the pelvis somehow 13:50 < nmz787> unless there's something fundamental to having an evolutionarily-premature baby, like social development shit, i.e. learned shit rather than genetic/molecular-hereditary 13:51 < nmz787> it was def easier for my wife to have kid carried around in her womb, than it is in her arms 13:53 -!- jqtrde [~jqtrde@12.227.183.66] has quit [Ping timeout: 264 seconds] 14:00 < nmz787> so when are we starting a commune? 14:04 < kanzure> commune was 2006 you sort of missed it 14:04 < nmz787> damn 14:04 < nmz787> that would've been the perfect year 14:05 < nmz787> just before I decided to go to college 14:08 -!- jb55 [~jb55@2605:8d80:4c4:680f:a2af:bdff:fef0:c102] has quit [Ping timeout: 260 seconds] 14:11 < nmz787> well if anyone's interested, I am up for buying at least 40 to 80 acres of buildable land here in Oregon near Portland 14:12 < kanzure> how much does a few hundred acres cost 14:14 < nmz787> around here (i.e. within 45-60 mins drive from Portland), between 1 and 2 million... but that's because of all the techies pushing prices up 14:15 < nmz787> 2-3 hours away that price would drop to half or a third 14:17 < nmz787> there's a pretty awesome peninsula ~2 hours from Portland, on a river... 255 acres for $470k https://www.landwatch.com/Marion-County-Oregon-Land-for-sale/pid/327300514 14:19 < kanzure> .tw https://twitter.com/SRouhanifard/status/993623088230170625 14:19 < yoleaux> Check out our updated clampFISH preprint: Exponential fluorescent amplification of individual RNAs using clampFISH probes. Features a working protocol, updated table of oligos, and expanded supplementary data set. https://www.biorxiv.org/content/early/2018/05/07/222794 https://pbs.twimg.com/media/DcoOuwpV0AEK_oM.jpg (@SRouhanifard) 14:31 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 246 seconds] 14:37 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 14:51 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 14:53 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 248 seconds] 14:56 -!- lewl [~lewl@184-207-126-174.pools.spcsdns.net] has joined ##hplusroadmap 15:05 -!- lewl [~lewl@184-207-126-174.pools.spcsdns.net] has quit [Ping timeout: 265 seconds] 15:17 -!- jqtrde [~jqtrde@2600:1700:290:3e10:42a3:ccff:fe65:94dd] has joined ##hplusroadmap 15:25 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: Malvolio] 15:31 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 15:33 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Client Quit] 15:37 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 15:57 -!- jqtrde [~jqtrde@2600:1700:290:3e10:42a3:ccff:fe65:94dd] has quit [Quit: jqtrde] 16:34 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has quit [Quit: Leaving.] 17:15 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 17:19 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 250 seconds] 17:21 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has joined ##hplusroadmap 17:27 -!- lewl [~lewl@pool-173-52-36-71.nycmny.fios.verizon.net] has joined ##hplusroadmap 17:58 -!- lewl [~lewl@pool-173-52-36-71.nycmny.fios.verizon.net] has quit [] 18:00 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 18:00 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 18:06 -!- rkos [rkos@228.ip-176-31-189.eu] has joined ##hplusroadmap 18:13 -!- strages [uid11297@gateway/web/irccloud.com/x-fakoqrrjpzibzvog] has joined ##hplusroadmap 18:34 -!- lewl [~lewl@pool-173-52-36-71.nycmny.fios.verizon.net] has joined ##hplusroadmap 18:34 < lewl> shhh 18:34 < lewl> yoyyoy 18:40 -!- Gurkenglas [~Gurkengla@dslb-188-102-074-205.188.102.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds] 19:18 -!- lewl [~lewl@pool-173-52-36-71.nycmny.fios.verizon.net] has quit [Remote host closed the connection] 19:30 -!- drewbot [~cinch@54.167.35.194] has joined ##hplusroadmap 19:39 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Quit: WeeChat 2.0] 19:40 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 20:36 -!- lewl [~lewl@64.94.31.206] has joined ##hplusroadmap 20:36 < lewl> omw bk to dc 20:43 < kanzure> https://techcrunch.com/2018/05/11/this-three-axis-tourbillon-movement-is-a-3d-printed-marvel/ 20:54 < lewl> sorry, that was meant for hacdc channel 20:54 < lewl> btw i finished some tensorflow basics github.com/lewlking 21:55 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: SCIENTISTS PREDICT ICE AGE] 21:58 -!- ebowden_ [~ebowden@128.250.0.209] has quit [Ping timeout: 240 seconds] 21:59 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 22:01 -!- lewl [~lewl@64.94.31.206] has quit [Remote host closed the connection] 22:42 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:6850:6f95:f9ee:9636] has quit [Quit: Leaving] 23:25 -!- ebowden [~ebowden@128.250.0.209] has joined ##hplusroadmap 23:37 -!- strages [uid11297@gateway/web/irccloud.com/x-fakoqrrjpzibzvog] has quit [Quit: Connection closed for inactivity] 23:47 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has quit [Ping timeout: 256 seconds] 23:54 < ebowden> nmz787, do you think you'd be able to produce some the out-of-production chips for the C64? 23:54 < ebowden> (Given how old their process node is.) --- Log closed Sun May 13 00:00:15 2018