--- Log opened Tue Jun 05 00:00:37 2018 00:02 -!- jtimon [~quassel@226.110.132.37.dynamic.jazztel.es] has quit [Ping timeout: 276 seconds] 00:05 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Quit: gone for now but not for good] 00:44 -!- poppingtonic [~brian@41.212.6.37] has joined ##hplusroadmap 00:44 -!- poppingtonic [~brian@41.212.6.37] has quit [Changing host] 00:44 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:14 -!- CheckDavid_ [uid14990@gateway/web/irccloud.com/x-fgykxscxgdgfjizu] has joined ##hplusroadmap 01:26 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Read error: Connection reset by peer] 01:29 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:29 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Client Quit] 01:44 < fenn> decommoditization of protocols 01:59 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 02:03 -!- t4nk [t4nk@gateway/shell/panicbnc/x-wrsfdvbqeehunuax] has quit [Ping timeout: 256 seconds] 02:18 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap 02:25 < jrayhawk> what 02:26 < jrayhawk> do you think opengl emerged from fairies and sunshine to be the blessed graphics API for all of god's children? 02:30 < jrayhawk> opengl exists because a monolithic corporate overlord developed it to give themselves a competitive advantage over the open industry standard that came before it 02:32 -!- CheckDavid_ [uid14990@gateway/web/irccloud.com/x-fgykxscxgdgfjizu] has quit [] 02:33 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-qmfktohzoremrsce] has joined ##hplusroadmap 03:01 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 256 seconds] 03:03 < jrayhawk> mp3.com, in refusing to distribute CDs, decommoditized the standard industry audio format 03:03 < jrayhawk> MONSTERS 03:09 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 03:24 < jrayhawk> AMD also released Mantle in 2013, (and, sortof half-relevantly, nVidia's had CUDA since 2007 with the caveat that CUDA can, at best, write to buffer objects, and has never directly supported framebuffer/blitting/CRTC/modesetting operations), so it's not like Apple is being the first defector in some marketplace prisoner's dilemma 03:24 < jrayhawk> literally the entire industry saw this transition coming 03:25 < fenn> why would the deprecate OpenCL 03:25 < fenn> they* 03:25 < jrayhawk> because there's no sense in developing two products that compete with eachother 03:25 < jrayhawk> see: wordstar, netscape 03:26 < fenn> providing compatibility libraries is competing with yourself? huh? 03:26 < jrayhawk> apple similarly makes it very difficult to develop on a bunch of their platforms with anything other than obj-c 03:27 < jrayhawk> they do provide compatibility libraries 03:27 < jrayhawk> they've merely deprecated them 03:28 < jrayhawk> By comparison, Microsoft doesn't ship OpenGL in the first place. 03:29 < jrayhawk> well, other than the basic platform stuff needed to make OpenGL 1.1 work 03:30 < fenn> are you sure about that? 03:30 < fenn> i had to download directX for windows 03:30 < fenn> maybe it was a version thing 03:30 < solene> I think that on Windows it's nvidia and amd which provided OpenGL 03:30 < solene> since they dropped it 03:31 < solene> nvidia binary driver on linux/freebsd/solaris also ships its own libGL 03:33 < jrayhawk> Yeah, they just have the platform interface bootstrap stuff that the main OpenGL standard obnoxiously left blank. 03:41 < fenn> "the Khronos Group announced that OpenCL would be merging into Vulkan in the future" 03:41 < fenn> this is actually the first i've even heard of Vulkan 03:42 -!- adlai [~adlai@unaffiliated/adlai] has quit [Read error: Connection reset by peer] 03:43 < jrayhawk> https://github.com/Microsoft/angle is pretty cool 03:44 < fenn> i want to run openCL or something like it on random bullshit phone graphics hardware 03:44 < fenn> to do neural networks, object recognition,e tc 03:46 < jrayhawk> Some of the Mali line supports Vulkan and OpenCL. 03:46 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Ping timeout: 250 seconds] 03:47 < jrayhawk> Most hardware is just implementing GLES, though. 03:48 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:55 < bluebear_> fenn: very carefully I would say that Vulkan is probably the way to go 03:55 < bluebear_> although I must admit using it is very annoing (like, 600 lines of code and still not even a triangle drawn) 03:56 < bluebear_> fortunately, the available examples are better and better; but not sure how it is with computation; vulkan can do it but not sure how 03:56 -!- adlai [~adlai@unaffiliated/adlai] has joined ##hplusroadmap 04:00 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 245 seconds] 04:06 < fenn> .wik moltenvk 04:06 < yoleaux> "MoltenVK is a software library which allows Vulkan applications to run on top of Metal on Apple's macOS and iOS operating systems. It is the first software component to be released for the Vulkan Portability Initiative, a project to have a subset of Vulkan run on platforms which lack native Vulkan drivers." — https://en.wikipedia.org/wiki/MoltenVK 04:07 < jrayhawk> Yeah, Khronos has big plans to software shim everything with everything 04:07 < fenn> good 04:10 < jrayhawk> it's not abundantly clear to me that they have the development budget to do so, but who knows? maybe mesa will fill that role eventually 04:41 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-qmfktohzoremrsce] has quit [Quit: Connection closed for inactivity] 05:38 -!- ebowden [~ebowden@128.250.0.198] has quit [Read error: Connection reset by peer] 05:38 -!- ebowden [~ebowden@128.250.0.198] has joined ##hplusroadmap 06:15 < kanzure> alright so our triangles are safe? 06:21 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 06:41 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 06:55 < kanzure> "An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides" https://pubs.acs.org/doi/abs/10.1021/ja000563a?journalCode=jacsat 06:57 < kanzure> .wik spiroligomer 06:57 < yoleaux> "Spiroligomers (also known as bis-peptides) are synthetic oligomers made by coupling pairs of bis-amino acids into a fused ring system. Spiroligomers are rich in stereochemistry and functionality because of the variety of bis-amino acids that are capable of being incorporated during synthesis." — https://en.wikipedia.org/wiki/Spiroligomer 06:57 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 07:00 < kanzure> this guy claims to have spiroligomers for nanopore dna sequencing https://www.youtube.com/watch?v=8X69_42Mj-g&t=9m 07:01 < kanzure> .title 07:01 < yoleaux> Clasp: Common Lisp using LLVM and C++ for Molecular Metaprogramming - YouTube 07:08 < kanzure> eudoxia would like this video 07:08 < kanzure> https://news.ycombinator.com/user?id=drmeister 07:09 < kanzure> https://github.com/clasp-developers/clasp 07:09 < kanzure> "Clasp is a new Common Lisp implementation that seamlessly interoperates with C++ libraries and programs using LLVM for compilation to native code. This allows Clasp to take advantage of a vast array of preexisting libraries and programs, such as out of the scientific computing ecosystem. Embedding them in a Common Lisp environment allows you to make use of rapid prototyping, incremental ... 07:09 < kanzure> ...development, and other capabilities that make it a powerful language." 07:09 < kanzure> oh that's nice i guess. alright. 07:21 -!- Cosmophyle [~cosmophil@207.189.2.225] has joined ##hplusroadmap 07:22 -!- Cosmophyle [~cosmophil@207.189.2.225] has quit [Remote host closed the connection] 07:24 -!- Cosmophile [~cosmophil@207.189.2.228] has quit [Ping timeout: 260 seconds] 07:32 -!- fr4nt1c [~enigma@2.239.26.118] has joined ##hplusroadmap 07:35 < kanzure> oh my god i forgot to harass freitas about data storage 07:35 < kanzure> he's still alive so that's nice 07:36 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 245 seconds] 07:48 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 240 seconds] 07:56 -!- Cory [~Cory@unaffiliated/cory] has quit [Ping timeout: 276 seconds] 07:57 < kanzure> .tw https://twitter.com/DocDellaire/status/1003960922719838209 07:57 < yoleaux> @emilylmullin Please raise the point that there may be no need for germline gene editing for most inherited diseases if pre-implantation genetic diagnosis (PGD) was more widely available and most importantly AFFORDABLE. (@DocDellaire, in reply to tw:1003638565602037762) 07:57 < kanzure> hmm. 07:57 < kanzure> .tw https://twitter.com/rosenblumandrew/status/1003665054095380480 07:57 < yoleaux> @emilylmullin I'd love to hear panelists respond to James Clapper's assertion that gene editing is a "weapon of mass destruction." Was this hyperbole, or are there genuinely terrifying scenarios, particularly in the hands of garage DIYers, or violent/unhinged folks? (@rosenblumandrew, in reply to tw:1003638565602037762) 08:03 < kanzure> overview https://www.statnews.com/2018/06/05/crisprcon-boston-crispr-gene-editing/ 08:04 -!- Cory [~Cory@unaffiliated/cory] has joined ##hplusroadmap 08:04 < kanzure> "“My question is: Is democratization of this technology something you all really want?” Cosme said to an audience of scientists. “It’s not a term we should be using lightly. I don’t think it should be a window dressing for community relations.”" 08:31 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 08:39 -!- Cosmophile [~cosmophil@207.189.2.228] has joined ##hplusroadmap 08:44 < kanzure> music https://www.youtube.com/watch?v=h8srncYvVAs 08:56 -!- fr4nt1c [~enigma@2.239.26.118] has quit [Remote host closed the connection] 09:09 -!- virus^ [~virus@185.65.134.167] has left ##hplusroadmap [] 09:09 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:8d50:5aba:8551:fe82] has joined ##hplusroadmap 09:26 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 09:27 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 09:38 -!- Kacia [~kacia@95.87.234.241] has quit [Remote host closed the connection] 09:38 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 09:38 -!- Kacia [~kacia@95.87.234.241] has quit [Read error: Connection reset by peer] 09:39 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 09:47 -!- jtimon [~quassel@226.110.132.37.dynamic.jazztel.es] has joined ##hplusroadmap 10:25 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 256 seconds] 11:08 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 11:09 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 265 seconds] 11:43 -!- hazirafel [~hazirafel@bzq-79-180-116-109.red.bezeqint.net] has joined ##hplusroadmap 11:46 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 11:57 -!- jqtrde [~jqtrde@173.195.78.226] has joined ##hplusroadmap 12:22 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 12:28 -!- Cosmophile [~cosmophil@207.189.2.228] has quit [Remote host closed the connection] 12:34 -!- Cosmophile [~cosmophil@207.189.2.228] has joined ##hplusroadmap 12:39 -!- hazirafel [~hazirafel@bzq-79-180-116-109.red.bezeqint.net] has quit [Quit: Leaving] 13:00 < kanzure> hmm 13:39 -!- jqtrde [~jqtrde@173.195.78.226] has quit [Ping timeout: 256 seconds] 13:49 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 13:52 -!- jtimon [~quassel@226.110.132.37.dynamic.jazztel.es] has quit [Remote host closed the connection] 14:04 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has joined ##hplusroadmap 14:49 -!- Kacia [~kacia@95.87.234.241] has quit [Remote host closed the connection] 15:15 -!- jqtrde [~jqtrde@68.177.129.217] has joined ##hplusroadmap 15:41 -!- Cosmophile [~cosmophil@207.189.2.228] has quit [Remote host closed the connection] 16:21 -!- jqtrde [~jqtrde@68.177.129.217] has quit [Ping timeout: 256 seconds] 16:27 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 16:29 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 17:00 -!- Cosmophile [~cosmophil@207.189.2.228] has joined ##hplusroadmap 17:01 -!- jqtrde [~jqtrde@173.195.78.226] has joined ##hplusroadmap 17:12 < kanzure> ".. have apprentices at each institution, with a traveling master whose cost is shared across institutions." (for glassblowing expertise shortage) 17:12 < kanzure> from https://news.ycombinator.com/item?id=17240776 17:21 < kanzure> music https://www.youtube.com/watch?v=smBda5hbcS0 17:22 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 17:35 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 240 seconds] 17:41 -!- Cosmophile [~cosmophil@207.189.2.228] has quit [Remote host closed the connection] 17:50 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 17:53 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 18:13 -!- jqtrde [~jqtrde@173.195.78.226] has quit [Ping timeout: 240 seconds] 19:05 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 19:23 < kanzure> "Ectopic pregnancies in unusual locations" https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-970051 19:56 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 240 seconds] 20:10 < kanzure> huh i actually don't like the site for PGD https://genomicprediction.com/ 20:16 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has quit [Quit: Leaving.] 20:17 < kanzure> "Genetic power is the most awesome force ever seen on this planet." 20:17 < kanzure> thanks jeffy g 20:29 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Read error: Connection reset by peer] 20:30 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 20:30 < kanzure> https://www.netflix.com/watch/80243752?trackId=14277283 20:43 < fenn> .title 20:43 < yoleaux> Explained | Netflix Official Site 20:43 < fenn> "Vox digs into a wide range of topics such as the rise of cryptocurrency, why diets fail, and the wild world of K-pop" 20:59 < kanzure> oh, it was meant to be the link to their d-baby episode 20:59 < kanzure> awful web developers i guess 22:00 < kanzure> .title http://libgen.io/book/index.php?md5=1A35EF1D72456502BE585C9AF2BCCB0E 22:00 < yoleaux> Library Genesis: John Harris - Enhancing Evolution: The Ethical Case for Making Better People 22:02 -!- ebowden_ [~ebowden@128.250.0.198] has joined ##hplusroadmap 22:04 -!- ebowden [~ebowden@128.250.0.198] has quit [Read error: Connection reset by peer] 22:04 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Quit: gone for now but not for good] 22:07 < kanzure> people seem to certainly enjoy talking about the morality and ethics of genetic engineering... 22:07 < kanzure> even more than they enjoy thinking about enhancement 22:10 < kanzure> https://interplanetaryfest.org/events/ 22:15 < kanzure> private placement life insurance stuff http://gsrp.com/resources/PPLI/PPLI_Tutorial.pdf 22:45 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:8d50:5aba:8551:fe82] has quit [Quit: Leaving] 22:46 -!- Cory [~Cory@unaffiliated/cory] has quit [Ping timeout: 256 seconds] 22:57 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 23:32 -!- mrdata [~mrdata@unaffiliated/mrdata] has quit [Ping timeout: 240 seconds] 23:37 < ebowden_> http://semimd.com/blog/tag/cebl/ 23:39 < ebowden_> Cheaper prototyping would be nice. --- Log closed Wed Jun 06 00:00:38 2018