--- Log opened Wed Jun 20 00:00:51 2018 01:13 -!- strages [uid11297@gateway/web/irccloud.com/x-eqtflgdghdrfuxtu] has quit [Quit: Connection closed for inactivity] 01:15 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 240 seconds] 01:22 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Remote host closed the connection] 01:23 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 01:23 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 01:26 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 01:27 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 255 seconds] 01:33 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 245 seconds] 01:38 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 01:43 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 256 seconds] 01:43 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 01:43 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 01:45 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 01:52 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 240 seconds] 01:52 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 01:57 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 02:05 -!- ebowden_ [~ebowden@124.183.192.230] has joined ##hplusroadmap 02:08 -!- ebowden [~ebowden@2001:8003:1014:2500:19ae:bccd:490c:12f] has quit [Ping timeout: 265 seconds] 02:12 -!- jtimon [~quassel@40.28.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 02:32 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap 02:43 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 02:46 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 03:09 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:43 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 03:43 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 245 seconds] 03:51 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Remote host closed the connection] 03:57 -!- vurtz [~vurtz@2a02:c7d:ba9:9b00:3d91:4b8f:f25:1c69] has joined ##hplusroadmap 04:29 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 04:33 -!- ebowden_ [~ebowden@124.183.192.230] has quit [Ping timeout: 256 seconds] 04:42 -!- karkomah [~0x@a94-132-223-187.cpe.netcabo.pt] has joined ##hplusroadmap 04:49 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 04:53 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 05:16 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 255 seconds] 05:16 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 05:20 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 240 seconds] 05:24 -!- vurtz [~vurtz@2a02:c7d:ba9:9b00:3d91:4b8f:f25:1c69] has quit [Quit: Leaving] 05:39 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 05:44 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 260 seconds] 05:45 < kanzure> "Compact fusion energy based on the spherical tokamak" http://iopscience.iop.org/article/10.1088/1741-4326/aa8c8d 06:03 -!- ebowden [~ebowden@2001:8003:1014:2500:19ae:bccd:490c:12f] has joined ##hplusroadmap 06:19 -!- ebowden_ [~ebowden@124.183.192.230] has joined ##hplusroadmap 06:23 -!- ebowden [~ebowden@2001:8003:1014:2500:19ae:bccd:490c:12f] has quit [Ping timeout: 276 seconds] 06:31 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 06:31 < kanzure> .title http://dnascript.co/blog50nt 06:31 < yoleaux> Blog - Part 2 - 50nt synthesis 06:32 < kanzure> "DNA Script announces first milestone: successful enzymatic synthesis of 50nt strand of DNA" 06:32 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 06:33 < kanzure> https://www.linkedin.com/pulse/enzymatic-dna-synthesis-coming-jiahao-huang/?published=t 06:33 < kanzure> "Nuclera is developing a next-generation DNA synthesis and automation platform based on engineered terminal deoxynucleotidyl transferases (TdT) to enable the production of gene and genome libraries. Our TdT enzymes are proven to quantitatively incorporate a wide variety of reversibly terminating nucleotide triphosphates of all four nucleobases. We are the only enzymatic DNA synthesis company ... 06:34 < kanzure> ...capable of sequence-specific oligonucleotide production." 06:34 < kanzure> finally, someone saying upfront what they actually do 06:36 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 245 seconds] 06:38 < kanzure> .tw https://twitter.com/GenScript/status/1009050713958297601 06:38 < yoleaux> DNA distribution kits for iGEM China teams have arrived. Our China colleagues will distribute them soon. @iGEM #iGEM2018 https://pbs.twimg.com/media/DgDeRqhWkAA2pEg.jpg (@GenScript) 06:53 -!- karkomah [~0x@a94-132-223-187.cpe.netcabo.pt] has quit [Quit: Going offline, see ya! (www.adiirc.com)] 06:57 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 07:25 -!- juri_ [~juri@205.166.94.181] has quit [Ping timeout: 265 seconds] 07:32 -!- juri_ [~juri@205.166.94.181] has joined ##hplusroadmap 07:43 < kanzure> hmm 07:47 -!- bird_hops [~eiki@78-11-233-153.static.ip.netia.com.pl] has joined ##hplusroadmap 07:55 < kanzure> bird_hops: be greeted 08:08 -!- jtimon [~quassel@40.28.134.37.dynamic.jazztel.es] has quit [Remote host closed the connection] 08:21 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 08:25 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 240 seconds] 08:34 < bird_hops> kanzure: hello, thank you 08:50 < kanzure> "Product-oriented chemical surface modification of a levansucrase (SacB) via an ene-type reaction" http://pubs.rsc.org/en/Content/ArticleLanding/2018/SC/C8SC01244J#!divAbstract 09:05 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:5cfc:a15f:b0cb:77f6] has joined ##hplusroadmap 09:07 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 09:45 -!- scarletbutterfly [~scarletbu@cpc147664-warw19-2-0-cust423.3-2.cable.virginm.net] has joined ##hplusroadmap 09:52 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has joined ##hplusroadmap 09:55 -!- scarletbutterfly [~scarletbu@cpc147664-warw19-2-0-cust423.3-2.cable.virginm.net] has left ##hplusroadmap ["Leaving"] 10:08 -!- strages [uid11297@gateway/web/irccloud.com/x-kevyxnegyksukrtv] has joined ##hplusroadmap 10:26 -!- vurtz [~vurtz@2a02:c7d:ba9:9b00:3d91:4b8f:f25:1c69] has joined ##hplusroadmap 10:34 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 260 seconds] 10:47 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has quit [Remote host closed the connection] 11:05 < kanzure> march 2019 berlin sens foundation conference https://www.undoing-aging.org/ 11:08 < kanzure> https://www.undoing-aging.org/videos 11:14 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 264 seconds] 11:18 -!- jqtrde [~jqtrde@173.195.78.226] has joined ##hplusroadmap 11:33 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 11:42 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 264 seconds] 11:56 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 11:58 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Read error: Connection reset by peer] 11:58 -!- virus^ [~virus@185.65.134.168] has quit [Quit: .] 11:58 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 256 seconds] 12:02 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has joined ##hplusroadmap 12:03 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 12:35 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has quit [Remote host closed the connection] 13:11 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has joined ##hplusroadmap 13:15 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 13:16 < kanzure> https://www.quantamagazine.org/omnigenic-model-suggests-that-all-genes-affect-every-complex-trait-20180620/ 13:16 < kanzure> "An expanded view of complex traits: From polygenic to omnigenic" https://www.cell.com/cell/fulltext/S0092-8674(17)30629-3 13:59 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 14:30 < fenn> this EU copyright law is seriously bad news 14:42 < fenn> gotta get scraping before literally everything disappears 14:43 -!- lewl [~lewl@173-13-235-89-WashingtonDC.hfc.comcastbusiness.net] has quit [] 14:43 < kanzure> targets plz? maybe we should look at hplusroadmap logs for hyperlinks. 14:43 < fenn> it's too broad to provide targets 14:43 < fenn> any site with user-uploaded content 14:51 -!- bird_hops [~eiki@78-11-233-153.static.ip.netia.com.pl] has quit [Quit: Leaving] 15:07 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 15:25 -!- sachy [~sachy@78.108.102.220] has joined ##hplusroadmap 15:25 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Quit: leaving] 15:25 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 15:26 < nmz787> UCLA medical center processes 1800 cases per year with their Electron Microscope... or about 7-10 a day 15:38 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 15:45 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 265 seconds] 15:58 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 16:00 -!- jqtrde [~jqtrde@173.195.78.226] has quit [Ping timeout: 240 seconds] 16:15 -!- jqtrde [~jqtrde@173.195.78.226] has joined ##hplusroadmap 16:20 -!- vurtz [~vurtz@2a02:c7d:ba9:9b00:3d91:4b8f:f25:1c69] has quit [Quit: Leaving] 16:27 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 276 seconds] 16:33 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 16:37 -!- sachy [~sachy@78.108.102.220] has quit [Quit: Leaving.] 16:57 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 17:01 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 248 seconds] 17:11 < maaku> Does anyone know of a blocks-world (think: minecraft) model that permits reasonably accurate mechanical mechanisms? 17:12 < maaku> I'm asking with the purpose of testing kinematic self-replicating machine designs in a virtual environment 17:13 < maaku> but one for which the resulting design, although digital, reasonably represents reality in terms of being represented by cogs and gears not magic-block-matter 17:16 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 17:22 -!- strages [uid11297@gateway/web/irccloud.com/x-kevyxnegyksukrtv] has quit [Quit: Connection closed for inactivity] 17:42 < jrayhawk> Blender if serious, Garry's Mod if not 18:00 -!- jqtrde [~jqtrde@173.195.78.226] has quit [Ping timeout: 256 seconds] 19:04 -!- jqtrde [~jqtrde@216.9.110.1] has joined ##hplusroadmap 19:46 -!- jqtrde [~jqtrde@216.9.110.1] has quit [Ping timeout: 240 seconds] 19:49 -!- jqtrde [~jqtrde@216.9.110.12] has joined ##hplusroadmap 19:55 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 19:57 -!- jqtrde [~jqtrde@216.9.110.12] has quit [Ping timeout: 245 seconds] 20:08 < kanzure> "Sex reversal following deletion of a single distal enhancer of Sox9" http://science.sciencemag.org/content/early/2018/06/13/science.aas9408 https://www.crick.ac.uk/news/science-news/2018/06/14/non-coding-dna-changes-the-genitals-youre-born-with/ 20:09 < kanzure> "Geometry of the nucleus: a perspective on gene expression regulation" https://www.sciencedirect.com/science/article/pii/S1367593114000647 20:11 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Read error: Connection reset by peer] 20:11 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 20:13 -!- lewl_ [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 20:13 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Read error: Connection reset by peer] 20:15 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 20:19 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Remote host closed the connection] 20:19 -!- lewl_ [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Ping timeout: 268 seconds] 20:19 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has joined ##hplusroadmap 20:24 -!- lewl [~lewl@96-88-198-77-static.hfc.comcastbusiness.net] has quit [Ping timeout: 264 seconds] 20:29 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 20:41 -!- lewl [~lewl@2601:143:8000:595d:689e:4747:ef1d:d31a] has joined ##hplusroadmap 21:29 -!- gwillen [~gwillen@unaffiliated/gwillen] has quit [Ping timeout: 240 seconds] 21:56 -!- Bala [~Bala@103.211.53.97] has joined ##hplusroadmap 22:07 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 260 seconds] 22:08 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has joined ##hplusroadmap 22:09 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:5cfc:a15f:b0cb:77f6] has quit [Quit: Leaving] 22:10 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 22:20 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 22:24 -!- jqtrde [~jqtrde@142-254-106-160.dsl.dynamic.fusionbroadband.com] has quit [Ping timeout: 256 seconds] 22:27 -!- Bala [~Bala@103.211.53.97] has left ##hplusroadmap ["Leaving"] 23:48 -!- Solgriffin [sid282649@gateway/web/irccloud.com/x-kojqpiefkxyuhtla] has quit [Ping timeout: 276 seconds] 23:55 -!- Solgriffin [sid282649@gateway/web/irccloud.com/x-wxvrtvlfioqrbghi] has joined ##hplusroadmap 23:55 -!- preview [~quassel@2407:7000:8423:b00::2] has joined ##hplusroadmap 23:55 -!- Solgriffin [sid282649@gateway/web/irccloud.com/x-wxvrtvlfioqrbghi] has quit [Max SendQ exceeded] --- Log closed Thu Jun 21 00:00:52 2018