--- Log opened Mon Nov 26 00:00:34 2018
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03:46 < Jay_Dugger> Good morning.
04:22 < fenn> .title
04:22 < yoleaux> AP Exclusive: First gene-edited babies claimed in China
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05:44 < kanzure> .title https://www.youtube.com/watch?v=th0vnOmFltc
05:44 < yoleaux> About Lulu and Nana: Twin Girls Born Healthy After Gene Surgery As Single-Cell Embryos - YouTube
05:46 < kanzure> HeJiankuiLab@gmail.com
05:46 < kanzure> http://www.sustc-genome.org.cn/
05:46 < kanzure> "Only for serious disease, never vanity (有所为更有所不为)"
05:46 < kanzure> welp there you go
05:46 < kanzure> more cowards
06:04 < kanzure> https://old.reddit.com/r/worldnews/comments/a0fdr7/first_geneedited_babies_claimed_in_china_a
06:27 < kanzure> .title https://news.ycombinator.com/item?id=18530906
06:27 < yoleaux> First gene-edited babies claimed in China | Hacker News
06:30 < kanzure> "one can raise IQ several standard deviations by editing <200 alleles" https://arxiv.org/pdf/1408.3421.pdf
06:35 < kanzure> .title https://www.zhihu.com/question/303671507
06:35 < yoleaux> 400 Bad Request
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07:07 < kanzure> .title https://lists.linuxfoundation.org/pipermail/lightning-dev/2018-November/001643.html
07:07 < yoleaux> [Lightning-dev] [PATCH] First draft of option_simplfied_commitment
07:07 < kanzure> .title https://lists.linuxfoundation.org/pipermail/lightning-dev/2018-November/001635.html
07:07 < yoleaux> [Lightning-dev] Rendez-vous proposal with ephemeral key switch
07:12 < kanzure> .tw https://twitter.com/razibkhan/status/1066904324226330624
07:12 < yoleaux> i am having conversations on twitter about the details and feasibility about genetically engineering humans in the next 5-10 years. the rest is commentary. (@razibkhan)
07:21 < kanzure> https://www.technologyreview.com/s/612465/crispr-inventor-feng-zhang-calls-for-moratorium-on-baby-making/
07:21 < kanzure> i'm calling it, the gene editing summit in hong kong will draft a moratorium statement
07:21 < kanzure> and it will be mandatory for academic institutions
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07:46 < kanzure> moratorium on moratoriums
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08:07 < pompolic> moratorium on bioconservatives
08:10 < kanzure> .title https://www.nature.com/articles/d41586-018-07545-0
08:10 < yoleaux> Genome-edited baby claim provokes international outcry
08:11 < kanzure> "Making gene-edited babies goes against guidelines released by China's health ministry in 2003 but does not break any laws."
08:12 < kanzure> .tw https://twitter.com/Aiims1742/status/1067041468496470016
08:12 < yoleaux> @matthewherper @sxbegle Cc: @EricTopol @emilylmullin @lisamjarvis @pknoepfler @antonioregalado @MMarchioneAP Unequivocal distancing from the #CRISPR babies by the PI’s University. https://pbs.twimg.com/media/Ds7kjv8V4AIL_LE.jpg (@Aiims1742, in reply to tw:1067040741069852672)
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08:14 < kanzure> .title https://m.jiemian.com/article/2654280.html?from=timeline&isappinstalled=0
08:14 < yoleaux> 122位科学家发联合声明：强烈谴责“首例免疫艾滋病基因编辑” | 界面新闻
08:15 < kanzure> http://sustc.edu.cn/en/info_focus/2871
08:16 < kanzure> .title http://www8.nationalacademies.org/onpinews/newsitem.aspx?RecordID=11262018
08:16 < yoleaux> Statement from the Organizing Committee on Reported Human Embryo Genome Editing
08:18 < kanzure> "A year ago, after months of planning leading up to the Second International Summit on Human Genome Editing, China quietly bowed out, David Baltimore of the California Institute of Technology, chairman of the meeting’s organizing committee, told STAT. The development has not previously been reported and was not announced by the organizers, who were hesitant to discuss the reasons."
08:19 < kanzure> .tw https://twitter.com/paulinemacco/status/1067064892857798658
08:19 < yoleaux> You can watch the live webcast of the 2nd International Summit on Human Genome Editing via the link, starts Tues 27 08.30 HKT, 0.30 GMT (hmmm). After today's announcements on designer babies it will be interesting! http://www.nationalacademies.org/gene-editing/2nd_summit/webcast/index.htm #GeneEditSummit (@paulinemacco)
08:20 < fenn> were the kids CCR5 knockouts?
08:20 < fenn> what did they actually do
08:22 < kanzure> http://china.huanqiu.com/article/2018-11/13647324.html
08:22 < kanzure> http://news.163.com/18/1126/19/E1IHABET0001875N.html
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08:28 < fenn> i wonder why they specified female HIV negative and male HIV positive, instead of the other way around
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10:35 < kanzure> https://twitter.com/i/moments/1066998941076602880
10:37 < kanzure> ".. He has been on unpaid leave since February. The university administration and the biology department, of which He is a member, had no knowledge of He’s experiments, it said."
10:38 < kanzure> "He is the founder and chairman of Direct Genomics, a gene-testing startup based in Shenzhen, according to a Chinese government-run website on companies. Sina.com, an established Chinese news publication, reported in April that Direct Genomics received 218 million yuan ($31 million) in venture capital funding that month."
10:41 < kanzure> "Is enhancement the price of prevention in human gene editing?" https://www.liebertpub.com/doi/10.1089/crispr.2018.0040
10:42 < kanzure> https://www.technologyreview.com/s/612466/the-chinese-scientist-who-claims-he-made-crispr-babies-has-been-suspended-without-pay/
10:43 < kanzure> .title http://3g.163.com/news/article_cambrian/E1IBVFD20001899O.html
10:43 < yoleaux> 针对"基因编辑婴儿" 122位科学家发声明强烈谴责_手机网易网
10:44 < kanzure> "Draft ethical principles for therapeutic assisted reproductive technologies" https://www.liebertpub.com/doi/10.1089/crispr.2018.0051
10:44 < kanzure> (he jiankui)
10:51 < kanzure> fenn: "possibly something with potential HIV genome transfer from sperm that's less likely in eggs, or to avoid dealing with mother-to-child transfer during birth"
10:51 < kanzure> fenn: "probably just to make it easier to claim that they're saving children from HIV, while taking minimal risk since I doubt there's a real risk if the mother is negative"
10:51 < kanzure> "instead of doing it in healthy parents, since then they wouldn't have the blanket excuse of preventing disease"
10:58 < fenn> insight mars landing live stream https://youtu.be/wwMDvPCGeE0 https://youtu.be/bGD_YF64Nwk
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11:13 < fenn> T-45 minutes
11:13 < fenn> or maybe 40
11:13 < fenn> "Atmospheric entry is expected around 11:47 a.m. PST (2:47 p.m. EST) and touchdown, about seven minutes later.""
11:23 < l_wl> tyty
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12:17 < fenn> spoiler alert https://i.imgur.com/pHqh65q.png
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12:34 < superkuh> https://scontent-ort2-2.xx.fbcdn.net/v/t1.0-9/46908912_1959009130832691_7937260229144608768_o.jpg?_nc_cat=106&_nc_ht=scontent-ort2-2.xx&oh=e7cc7acda6255d920884857b72d867a8&oe=5C661AB0
12:34 < superkuh> (higher res)
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12:36 < fenn> http://mars.nasa.gov/insight/multimedia/raw-images/
13:14 < kanzure> https://www.statnews.com/2018/11/26/rice-university-opens-investigation-into-researcher-who-worked-on-crisprd-baby-project/
13:14 < kanzure> "Deem told the AP that he was in China when participants in the study consented to join the research. Deem also said that had “a small stake” and is on the scientific advisory boards of He’s two companies."
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15:26 < kanzure> hmph
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16:15 < kanzure> .tw https://twitter.com/JSheltzer/status/1067157934667382784
16:15 < yoleaux> @StuartJRitchie “I’ve been in contact with the Shenzhen team and have seen the data,” says George Church. https://www.statnews.com/2018/11/26/claim-of-crispred-baby-girls-stuns-genome-editing-summit/ (@JSheltzer, in reply to tw:1067148234974474240)
16:24 < kanzure> "this is bad news for tibetans since their high altitude gene is known even the andes high alt adaptations are being discovered which is really one of the closest things to a genetic super ability you can get. so it will only be a few decades more until this last barrier to han colonization of tibet falls."
16:24 < kanzure> strange perspective, but okay.
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16:51 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=06c774b7 Bryan Bishop: transcript: intro >> http://diyhpl.us/diyhpluswiki/transcripts/human-genome-editing-summit/2018-hong-kong/intro/
16:51 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=a3748d5d Bryan Bishop: trnascript: carrie lam >> http://diyhpl.us/diyhpluswiki/transcripts/human-genome-editing-summit/2018-hong-kong/carrie-lam/
16:55 < kanzure> webcast http://nationalacademies.org/gene-editing/2nd_summit/webcast/index.htm
16:58 < kanzure> https://livestream.com/accounts/7036396/events/8464254
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17:04 < kanzure> now they are calling up 200 professors on stage for group extermination
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17:22 < kanzure> .tw https://twitter.com/CRISPRjournal/status/1067217722629607425
17:22 < yoleaux> David Baltimore opens #GeneEditSummit in Hong Kong with a reference to Brave New World: “Although Huxley could not have conceived of genome engineering... we should take to heart the warning implicit in that book.” https://pbs.twimg.com/media/Ds-EyZwWkAEjZem.jpg (@CRISPRjournal)
17:22 < kanzure> pfffft
17:23 < kanzure> man this is going to be so lame
17:30 < kanzure> "... it would go against an agreement reached by the scientific community in 2015 to pause such germline editing (making changes to genes that can be inherited by children)."
17:30 < kanzure> an agreement... what.
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17:54 < Jay_Dugger> Hmm.
18:09 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e343473a Bryan Bishop: transcript: dana carroll >> 
18:12 < kanzure> hah "“There are safe and effective ways to protect children from HIV transmission, so the study as reported does not appear to address an unmet medical need.”"
18:13 < kanzure> we should form the asilomar reversion liberation army and finally stop this nonsense
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18:24 < kanzure> https://www.amazon.com/Crack-Creation-Editing-Unthinkable-Evolution/dp/0544716949/
18:29 < jrayhawk> huh, when did cgit die
18:30 < kanzure> 1993
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18:54 < jrayhawk> well, that's fixed, now.
18:54 < jrayhawk> Additionally, I've re-enabled commands and web edits on the wikis.
18:54 < jrayhawk> With any luck, I haven't even introduced any horrifying security vulnerabilities.
18:54 < kanzure> i think you disabled those things on purpose
18:55 < jrayhawk> They broke in a confusing way due to an apache upgrade and I made them break in a more explicit way on purpose.
18:55 < jrayhawk> Although the newuser captcha is probably broken because lol Google product support
19:00 < jrayhawk> i should migrate to a comedy ward cunningham captcha scheme
19:05 < nmz787> re: high-altitude gene evil plots... I was thinking more like disabling all the tibetan population's ability, forcing them out of their homeland
19:39 < kanzure> .tw https://twitter.com/paulinemacco/status/1067259770300559361
19:39 < yoleaux> Interesting Islamic perspective on genome editing from Mohammed Qhaly @HBKU - authority of one's body is limited for the individual, as person is considered a creation of god #geneeditsummit (@paulinemacco)
19:41 < kanzure> .tw https://twitter.com/CRISPRjournal/status/1067239925391679488
19:41 < yoleaux> Dana Carroll points to challenges with fair distribution of CRISPR therapy by analogy to thalassemia: “It is inconceivable that complex, expensive therapies could be made broadly available in high-risk areas [Africa, Asia]. I don’t have any bright ideas.” #GeneEditSummit (@CRISPRjournal)
19:41 < kanzure> .tw https://twitter.com/kanzure/status/1067242117003653120
19:41 < yoleaux> @CRISPRjournal Uh, (infectious) viral therapies could be produced cheaply. Next question. (@kanzure, in reply to tw:1067239925391679488)
20:17 < Malvolio> i wonder if one's allowed to open-source one's genome or whatever
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23:34 < nmz787> kanzure: did you ever get a microscope? I am considering purchasing one for soldering work
--- Log closed Tue Nov 27 00:00:35 2018