--- Log opened Thu Apr 25 00:00:44 2019 --- Day changed Thu Apr 25 2019 00:00 -!- Livestradamus [~Livestrad@unaffiliated/livestradamus] has joined ##hplusroadmap 00:06 -!- sachy [~sachy@78.108.102.220] has quit [Ping timeout: 244 seconds] 00:16 < fenn> https://www.newscientist.com/article/2191814-we-may-finally-know-what-causes-alzheimers-and-how-to-stop-it/ the P. gingivalis gum/brain infection hypothesis 01:57 < archels> brush your teeth, kids! 02:03 < fenn> i'm somewhat skeptical; wouldn't somebody have noticed a correlation between gum disease and alzheimers by now? 02:58 < archels> > In response to the new findings, David Reynolds of the Alzheimer’s UK charity said he is dubious that P. gingivalis causes Alzheimer’s, because of the evidence showing that a person’s genes play a crucial role in the disease. “Strong genetic evidence indicates that factors other than bacterial infections are central to the development of Alzheimer’s, so these new findings need to be 02:58 < archels> taken in the context of this existing research,” he said in a statement. 02:59 < archels> a somewhat puzzling response, no? genetic factors do not rule out the gingivitis theory or vice versa 02:59 < archels> and a very conservative response overall 03:04 < archels> .title https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105987/ 03:04 < yoleaux> Note: Antimicrobial Susceptibilities of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens spp. Isolated in Spain 03:04 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 03:06 < archels> hm, do antibiotics typically make it past the BBB? 03:06 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Read error: Connection reset by peer] 03:07 < archels> looks like yes, they can https://aac.asm.org/content/aac/33/7/1078.full.pdf 03:07 < archels> mean concentrations in serum were 4.7 pg/ml for the doxycycline dose of 100 mg b.i.d. and 7.5 ,ug/ml for 200 mg b.i.d., 2 to 3 h after the last drug administration. The corresponding levels for cerebrospinal fluid were 0.6 and 1.1 pg/ml. 03:33 < fenn> http://mythic-ai.com/technology/ analog compute neural networks in flash memory chips 03:43 < fenn> https://medium.com/mythic-ai/mythic-hot-chips-2018-637dfb9e38b7 more technical presentation 03:44 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 03:48 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Read error: Connection reset by peer] 04:23 -!- adamsky [~adamsky3@178235181086.unknown.vectranet.pl] has joined ##hplusroadmap 04:24 < fenn> one of the figures shows the flash transistor array as an array of resistors. it occurs to me that you can literally use an array of transistors in the same way, as long as your neural network doesn't ever need to learn 04:24 < fenn> er, s/transistors/resistors/ 04:25 < fenn> so your e.g. speech recognition ASIC is just a grid of resistors of different sizes 04:25 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 04:25 < fenn> i'm sure there's a problem with this somewhere, because all interesting neural networks have some nonlinearity in them 04:27 < fenn> they say ReLu or other nonlinearity is provided by the ADC 04:36 -!- NikopolSohru [~Nikopol_@185.107.80.182] has joined ##hplusroadmap 04:36 -!- NikopolSohru [~Nikopol_@185.107.80.182] has quit [Changing host] 04:36 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has joined ##hplusroadmap 04:46 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Read error: Connection reset by peer] 05:02 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 05:11 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Read error: Connection reset by peer] 05:18 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 05:19 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Remote host closed the connection] 05:20 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 05:22 -!- adamsky [~adamsky3@178235181086.unknown.vectranet.pl] has quit [Ping timeout: 245 seconds] 05:38 -!- Cory [Cory@unaffiliated/cory] has quit [Ping timeout: 276 seconds] 05:44 -!- Pasha [Cory@unaffiliated/cory] has joined ##hplusroadmap 05:46 -!- Pasha is now known as Cory 06:03 -!- adamsky [~adamsky3@178235181086.unknown.vectranet.pl] has joined ##hplusroadmap 06:50 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has quit [Quit: Leaving] 06:52 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 246 seconds] 06:57 -!- adamsky [~adamsky3@178235181086.unknown.vectranet.pl] has quit [Ping timeout: 276 seconds] 07:39 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 08:25 -!- sachy [~sachy@91.146.121.5] has joined ##hplusroadmap 08:36 -!- strages [uid11297@gateway/web/irccloud.com/x-uozkarwaytsigccz] has joined ##hplusroadmap 08:48 -!- sachy [~sachy@91.146.121.5] has quit [Ping timeout: 246 seconds] 08:53 -!- cluelessperson [~cluelessp@unaffiliated/cluelessperson] has quit [Ping timeout: 257 seconds] 09:01 -!- l_wl [~l_wl@pool-108-45-141-95.washdc.fios.verizon.net] has joined ##hplusroadmap 09:07 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-vyptynolsedfuvck] has joined ##hplusroadmap 09:14 < kanzure> https://www.smithsonianmag.com/innovation/how-to-prepare-for-future-gene-edited-babies-180972027/ 09:15 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 258 seconds] 09:28 < fenn> get a bunker and fill it with gene guns 09:53 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Ping timeout: 258 seconds] 10:02 -!- superkuh [~superkuh@c-24-118-172-137.hsd1.wi.comcast.net] has joined ##hplusroadmap 10:02 -!- superkuh [~superkuh@c-24-118-172-137.hsd1.wi.comcast.net] has quit [Changing host] 10:02 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 10:58 < heath> spreelanka is using https://www.aquarium.bio/ 10:58 < heath> eric klavins mentioned this at dna23 11:15 < kanzure> i don't understand, so they want you to write code for human steps and then separately write code for automated steps? https://www.aquarium.bio/ 11:16 < kanzure> i think jcline's english language protocol parser was more advanced than this 11:16 < kanzure> it could convert from protocols to machine code 11:19 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-vyptynolsedfuvck] has quit [Quit: Connection closed for inactivity] 11:41 -!- Solgriffin__ [sid282649@gateway/web/irccloud.com/x-ldakbhuyhhyswkin] has quit [Remote host closed the connection] 11:41 -!- Solgriffin__ [sid282649@gateway/web/irccloud.com/x-vegbcdmgdzqaitcg] has joined ##hplusroadmap 12:10 -!- NikopolSohru [~Nikopol_@185.107.80.182] has joined ##hplusroadmap 12:10 -!- NikopolSohru [~Nikopol_@185.107.80.182] has quit [Changing host] 12:10 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has joined ##hplusroadmap 12:55 -!- cluelessperson [~cluelessp@unaffiliated/cluelessperson] has joined ##hplusroadmap 13:35 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 13:40 -!- delinquentme [~delinquen@c-73-15-72-140.hsd1.ca.comcast.net] has joined ##hplusroadmap 14:17 -!- LeoTal [~Adium@121.247.7.93.rev.sfr.net] has quit [Quit: Leaving.] 14:19 -!- LeoTal [~Adium@121.247.7.93.rev.sfr.net] has joined ##hplusroadmap 14:21 -!- LeoTal [~Adium@121.247.7.93.rev.sfr.net] has quit [Client Quit] 14:28 -!- delinquentme [~delinquen@c-73-15-72-140.hsd1.ca.comcast.net] has quit [Quit: Leaving] 14:42 -!- BitMEX_Chad [~BitMEX_Ch@2001:8003:5327:f000:a8a3:4b4a:29ef:b04a] has joined ##hplusroadmap 14:42 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has quit [Quit: Leaving] 14:44 -!- BitMEX_Chad [~BitMEX_Ch@2001:8003:5327:f000:a8a3:4b4a:29ef:b04a] has quit [Remote host closed the connection] 15:10 -!- BitMEX_Chad [~BitMEX_Ch@2001:8003:5327:f000:a8a3:4b4a:29ef:b04a] has joined ##hplusroadmap 15:10 -!- BitMEX_Chad [~BitMEX_Ch@2001:8003:5327:f000:a8a3:4b4a:29ef:b04a] has quit [Remote host closed the connection] 15:22 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 258 seconds] 15:26 -!- periffis [~g@66.205.193.233] has quit [Quit: periffis] 16:11 -!- LooCfur [~hello@loocfur.powered.by.lunarbnc.net] has quit [Quit: Free ZNC ~ Powered by LunarBNC: https://LunarBNC.net] 16:11 -!- LooCfur [~hello@loocfur.powered.by.lunarbnc.net] has joined ##hplusroadmap 16:19 -!- helleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 16:21 -!- Guest98078 [~talinck@98.29.27.253] has quit [Ping timeout: 246 seconds] 16:33 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 16:36 -!- helleshin [~talinck@98.29.27.253] has quit [Ping timeout: 250 seconds] 17:37 -!- Jay_Dugger [~jwdugger@47.185.249.138] has quit [Ping timeout: 255 seconds] 17:46 -!- mrdata-- [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap 17:50 -!- Jay_Dugger [~jwdugger@47.185.249.138] has joined ##hplusroadmap 18:13 -!- strages [uid11297@gateway/web/irccloud.com/x-uozkarwaytsigccz] has quit [Quit: Connection closed for inactivity] 18:27 -!- mrdata-- [~mrdata@unaffiliated/mrdata] has quit [Read error: Connection reset by peer] 19:54 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 19:54 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Disconnected by services] 19:54 -!- justan0theruser is now known as justanotheruser 20:01 -!- LeoTal [~Adium@121.247.7.93.rev.sfr.net] has joined ##hplusroadmap 20:45 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 258 seconds] 20:53 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:08 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 255 seconds] 22:21 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:29 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 246 seconds] --- Log closed Fri Apr 26 00:00:55 2019