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00:14 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=f2b54b0a Bryan Bishop: transcript: SNARKs >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/survey-of-progress-in-zero-knowledge-proofs-towards-trustless-snarks/
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00:41 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=05a31025 Bryan Bishop: transcript: threshold scriptless scripts >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/threshold-scriptless-scripts/
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00:45 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=00ccc54c Bryan Bishop: transcript: threshold scriptless scripts >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/threshold-scriptless-scripts/
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01:01 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e34ca8ce Bryan Bishop: transcript: bitml >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/bitml/
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01:08 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=d733b4cd Bryan Bishop: transcript: more bitml >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/bitml/
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01:10 < kanzure> .title https://news.ycombinator.com/item?id=20934919
01:11 < EmmyNoether> Leadership Transition Announced for MIT Media Lab | Hacker News
01:17 < kanzure> "Progression of Meiosis Is Coordinated by the Level and Location of MAPK Activation Via OGR-2 in Caenorhabditis elegans" https://www.genetics.org/content/212/1/213
01:23 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=1d98be60 Bryan Bishop: add more accurate transcript of the intro >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/intro/
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02:05 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=95998b24 Bryan Bishop: transcript: zkvm >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/zkvm/
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02:05 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=fc08c433 Bryan Bishop: transcript: zkvm >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/zkvm/
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02:06 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=8842a0db Bryan Bishop: add tweeter link >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/zkvm/
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02:29 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=3e0b615b Bryan Bishop: transcript: scriptless lotteries >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/scriptless-lotteries/
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02:52 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=b06a24fb Bryan Bishop: transcript: txprobe >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/txprobe/
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02:54 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=05f29e2e Bryan Bishop: transcript: more txprobe >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/txprobe/
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03:23 < CRM114> is there any research into generating sperm from stem cells?
03:24 < kanzure> all sperm is generated from stem cells
03:25 < kanzure> http://diyhpl.us/~bryan/papers2/bio/in-vitro-fertilization/Germline%20stem%20cells:%20Towards%20the%20regeneration%20of%20spermatogenesis%20-%202015.pdf
03:25 < kanzure> http://diyhpl.us/~bryan/papers2/bio/in-vitro-fertilization/In%20vitro%20spermatogenesis:%20how%20far%20from%20clinical%20application%3f%20-%202016.pdf
03:25 < kanzure> http://diyhpl.us/~bryan/papers2/bio/in-vitro-fertilization/Progress%20and%20future%20prospect%20of%20in%20vitro%20spermatogenesis%20-%202017.pdf
03:25 < kanzure> http://diyhpl.us/~bryan/papers2/bio/in-vitro-fertilization/Spermatogenesis%20following%20male%20germ-cell%20transplantation%20(mouse)%20-%201994.pdf
03:25 < kanzure> http://diyhpl.us/~bryan/papers2/bio/in-vitro-fertilization/Xenografting%20of%20testicular%20tissue%20pieces:%2012%20years%20of%20an%20in%20vivo%20spermatogenesis%20system%20-%202014.pdf
03:40 < CRM114> kanzure: thanks
03:46 < kanzure> now you are obligated to read all of the downstream work and tell me about the updates.
04:03 < CRM114> lol
04:16 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=5c6c30f9 Bryan Bishop: transcript: erlay >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/erlay/
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04:17 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=169ff9e1 Bryan Bishop: add references >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/erlay/
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04:34 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=48e237ae Bryan Bishop: transcript: OP_SECURETHEBAG >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/bip-securethebag/
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04:42 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=b68457fe Bryan Bishop: transcript: OP_STB >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/bip-securethebag/
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04:43 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=80b1261c Bryan Bishop: more words >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/bip-securethebag/
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05:10 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=9dda3134 Bryan Bishop: transcript: elastic block caps >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/elastic-block-caps/
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05:36 < kanzure> why aren't we doing mouse brain tissue dishes with electrodes for competing against machine learning
05:58 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=737906cf Bryan Bishop: transcript: oblivious memory with SGX >> 
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06:01 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=4345cee9 Bryan Bishop: transcript: add more words >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/scaling-oblivious-read-write/
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06:16 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=f3c21506 Bryan Bishop: transcript: PIR >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/private-information-retrieval/
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06:17 < faceface> kanzure: I'm fairly sure we are...
06:18 < faceface> IIRC there was a thermostat built using a rat brain culture
06:18 < faceface> I should pop along to biomakespace and ask...
06:18 < faceface> A big driver would be low powercosts. However, I'm not sure what AI ASICs consume
06:19 < faceface> Man my new reading glasses are insanely thick!
06:20 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=3d28ba0d Bryan Bishop: transcript: more PIR >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/private-information-retrieval/
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06:21 < kanzure> what
06:22 < faceface> https://www.livescience.com/852-brain-chip-rat-neurons.html
06:22 < kanzure> no the other bullshit
06:23 < faceface> lenses?
06:23 < kanzure> i'm too sleep deprived
06:23 < faceface> heh
06:23 < kanzure> and ill and i have two more presentations to give
06:23 < faceface> https://uk.iherb.com/pr/vitafusion-melatonin-adult-vitamins-sleep-support-natural-white-tea-with-passion-fruit-flavors-140-gummies/80498
06:23 < kanzure> http://diyhpl.us/~bryan/upcoming-slides/scalingbitcoin6/
06:24 < faceface> Aim to be 50% better than half the talks you've seen, and it will be easy
06:24 < faceface> Vaults eh?
06:25 < faceface> You should be a guest on Block Digest, they have started to suck recently
06:26 < faceface> Sounds reasonable.
06:26 < faceface> I'd be a signing server
06:27 < kanzure> you want me to be a guest on a shitty podcast what kind of friend are you
06:27 < faceface> lol
06:27 < faceface> I want a better podcast. Do it for me.
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07:11 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=694490c8 Bryan Bishop: transcript: wasabi wallet >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/zerolink-sudoku/
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07:35 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=372e47ef Bryan Bishop: transcript: prism >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/tel-aviv-2019/zerolink-sudoku/
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12:15 < CryptoDavid> Even with good guests a podcast with a bad host is a bad podcast.
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19:33 < fenn> TIL mitochondria fuse into huge cell-spanning networks
19:36 < fenn> https://blog.infino.me/could-aging-be-an-infectious-disease/
19:43 < fenn> "viruses have been found to interfere with this cell cycle in many ways. Some accelerate it, and others freeze it at specific locations. Many viruses freeze the cell cycle at this precise location to maximize viral replication."
19:43 < fenn> "Herpes-Simplex-1, which we’ve previously discussed is linked to both Alzheimer’s and heart disease, is known to specifically arrest cells at the G1/S checkpoint."
19:43 < fenn> "cells in the senescent state are what we traditionally think of as a primary marker of aging. Senescence is specifically characterized by cells arrested in the G1/S state. These cells produce high levels of reactive oxygen species."
19:46 < fenn> however, someone else says: "In the adult organism, most cells are arrested but they are not senescent. So cell cycle arrest is not a synonym of senescence."
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20:53 < jrayhawk> I read a couple papers about inhibiting those viruses using that pathway with a carnivorous plant extract. I wonder if I can find those again.
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20:59 < jrayhawk> https://scholar.google.com/scholar?q=sarracenia+%28+herpes+OR+papilloma+OR+HIV+OR+pox+OR+influenza+%29
21:00 < jrayhawk> .title https://search.proquest.com/openview/901e13364fe6d2d835c67ae802f69209/1?pq-origsite=gscholar&cbl=736337
21:00 < EmmyNoether> Sarracenia purperea: A Botanical Extract With Anti-papilloma Virus and Oncolytic Activity - ProQuest
21:01 < fenn> apparently thermal receipt paper contains high levels of BPA
21:04 < jrayhawk> https://www.oatext.com/Treatment-of-herpetic-cold-sores-with-an-extract-of-Sarracenia-Purpurea.php
21:09 < jrayhawk> .title https://www.youtube.com/watch?v=XRtizRcqUx8
21:09 < EmmyNoether> AHS18 Guillermo Ruiz - Phyto-biological Warfare: Antibacterial Activity of Plant Compounds - YouTube
21:18 < jrayhawk> SARS, VZV, and VV also use the CDK pathway, I think?
21:24 < jrayhawk> no wait, that was the wrong video
21:24 < jrayhawk> .title https://www.youtube.com/watch?v=2CkXbyeydX0
21:24 < EmmyNoether> AHS17 Phyto-biological Warfare: An Evolutionary Approach to Botanical Medicine - Guillermo Ruiz - YouTube
21:24 < jrayhawk> there we go
21:24 < fenn> jeez these patents with "0.1-99%" of each ingredient
21:32 < fenn> how long until google yanks AHS videos for promoting non-mainstream medicine?
21:33 < fenn> of course it will be with absolutely no explanation, "this video is unavailable"
21:33 < jrayhawk> they seem to be more into shadowbanning emergent medicine
21:34 < jrayhawk> rather than explicitly removing it
21:34 < jrayhawk> Or maybe something even softer than shadowbanning
21:35 < jrayhawk> so long as the form of censorship is hard to comprehend and talk about, it can't cause undesirable controversy
21:36 < jrayhawk> all hail our confusing gatekeeping overlords
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22:06 < fenn> "By enabling genetic complementation, fusion of the mitochondria allows for two mitochondrial genomes with different defects within the same organelle to individually encode what the other lacks."
22:07 < fenn> the obvious next step would seem to be adding mitochondria from multiple genetically diverse individuals in order to average out as many mutations as possible
22:10 < nmz787> fenn: yes re: BPA... I still shred it though
22:11 < nmz787> why can't we just pay google for 2000s era search interface???
22:11 < nmz787> like, I imagine time/cost of computation of weird searches is why they stopped supporting "nerd" tools... but I really wish we could just pay them or something to get the good search back
22:13 < fenn> i really doubt it has anything to do with cost of computation
22:14 < fenn> google will happily transcode your 10 hour video of trump saying "china china china"
22:14 < fenn> or store literally unlimited quantities of data on google drive
22:14 < fenn> up to several petabytes at least
22:15 < nmz787> hmm
22:15 < nmz787> true
22:16 < nmz787> but that also *might* get ad hits when people put that video on at some dance rave, or whatever
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--- Log closed Thu Sep 12 00:00:08 2019