--- Log opened Fri Oct 18 00:00:37 2019 00:04 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 268 seconds] 00:30 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 00:47 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 250 seconds] 01:33 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has joined ##hplusroadmap 01:58 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 02:02 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has quit [Remote host closed the connection] 02:03 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has joined ##hplusroadmap 02:09 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 265 seconds] 02:33 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 03:02 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 250 seconds] 03:14 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 03:44 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 268 seconds] 03:48 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 03:57 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 240 seconds] 04:02 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 04:16 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 264 seconds] 04:30 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 04:58 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 250 seconds] 05:01 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 240 seconds] 05:32 < adlai> the local Glecheioidea family appears to have a vicious toxoplasmosis [of the "upwards, but not northwards" variety]; does that warrant artificial selection, instead of letting well enough alone? (symbionts gonna symb...) 05:34 < adlai> incidenally they are quite crafty with the cases: bulk prepared from readily-available carpet fibres, tufts of dust bunched around the outside for sillouhette breaking 05:39 < adlai> naturally, carrying that giant heap of passive camo while relocating the juvenile arthropod phase does not lend itself to a long and storied lifespan. 05:43 * adlai wonders as to the repurposability of the husks as e.g. thermal insulation after abandonment by moth 05:49 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 05:51 < adlai> juvenile currently under investigation appears reasonably aware of both heat gradient [from nearby candleflame] and photon impulse [camera flash] 05:52 < adlai> camera flash, useless as ever, makes it rather less easy to get a good shot of the silouhette breaking 05:54 < adlai> the juvies are likely also constitutionally unaware of silouhette breaking as an aspect of camoflage effectiveness, and thus their efforts reduce it. 05:56 * adlai is open to suggestions about how to reasonably estimate juvenile's crawl speed with camo-case attached; confounding factors are that they hide upon photic impulse and frequently pause to reassess local sense gradient against ... neurology? 06:00 < adlai> they definitely are capable of rapid motion not exhibited in the absence of sharp changes to the macro gradient: e.g., placing a small candle so that the exhaust column passes skew-parallel to the juvenile, several caselengths away at perpendicular, correlated with a reduction in climb speed. 06:12 -!- purpleshift [purpleshif@gateway/vpn/mullvad/purpleshift] has joined ##hplusroadmap 06:23 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 240 seconds] 06:29 -!- pycer [~pycer@unaffiliated/pycer] has joined ##hplusroadmap 06:30 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 06:37 -!- Human_G33k [~HumanG33k@62.147.242.8] has joined ##hplusroadmap 06:38 -!- Human_G33k [~HumanG33k@62.147.242.8] has quit [Remote host closed the connection] 06:38 -!- Human_G33k [~HumanG33k@62.147.242.8] has joined ##hplusroadmap 06:40 -!- HumanG33k [~HumanG33k@62.147.242.8] has quit [Ping timeout: 240 seconds] 06:42 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 06:57 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 265 seconds] 07:12 -!- pycer [~pycer@unaffiliated/pycer] has quit [Quit: "your mom lol"] 07:38 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 07:49 < kanzure> "Technological challenges and milestones for writing genomes" https://science.sciencemag.org/content/366/6463/310 07:49 < kanzure> great to see my work without attribution 07:51 -!- yashgaroth [~ffffffff@2606:6000:ca84:b300:24af:2cd6:f992:7a0d] has joined ##hplusroadmap 08:00 < kanzure> .tw https://twitter.com/kanzure/status/1185206560429137920 08:00 < EmmyNoether> So great to see my hard work without attribution, save for my esteemed colleagues. New manuscript out now---> // "Technological challenges and milestones for writing genomes" https://science.sciencemag.org/content/366/6463/310 (@kanzure) 08:06 < kanzure> .title https://stm.sciencemag.org/content/11/514/eaax2014 08:07 < EmmyNoether> Mutant neuropeptide S receptor reduces sleep duration with preserved memory consolidation | Science Translational Medicine 08:08 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 245 seconds] 08:12 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 08:46 < adlai> at the risk of "crying wolf": what work is unattributed? 08:49 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Ping timeout: 268 seconds] 08:54 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 265 seconds] 08:55 -!- crockwork [~crockwork@66.205.193.158] has joined ##hplusroadmap 09:28 -!- Codaraxis__ [Codaraxis@gateway/vpn/mullvad/codaraxis] has quit [Remote host closed the connection] 09:29 -!- Codaraxis__ [Codaraxis@gateway/vpn/mullvad/codaraxis] has joined ##hplusroadmap 09:29 -!- Codaraxis__ is now known as Codaraxis 09:30 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds] 09:35 < c-c> kanzure: that article is naive tomfoolery anyway 09:35 < c-c> - with ideas like "virus proof mammalian chromosome", it defies the knowledge of the genome 09:36 < c-c> - hell, endoviruses are an important mechanism in mammals! You can't just "turn them off" and expect the organism to survive 09:38 < c-c> " they comprise up to 5-8% of the human genome (lower estimates of ~1%). " 09:40 -!- Dr-G [~Dr-G@unaffiliated/dr-g] has quit [Ping timeout: 276 seconds] 09:43 -!- justanotheruser [justanothe@gateway/vpn/nordvpn/justanotheruser] has joined ##hplusroadmap 09:43 < c-c> https://www.gwern.net/docs/genetics/editing/2019-ostrov.pdf 09:44 < c-c> kanzure: I think you might be attrib's 09:44 -!- Codaraxis [Codaraxis@gateway/vpn/mullvad/codaraxis] has quit [Ping timeout: 240 seconds] 10:02 -!- pycer [~pycer@unaffiliated/pycer] has joined ##hplusroadmap 10:02 -!- pycer [~pycer@unaffiliated/pycer] has quit [Remote host closed the connection] 10:35 -!- Codaraxis [Codaraxis@gateway/vpn/mullvad/codaraxis] has joined ##hplusroadmap 11:09 -!- Codaraxis [Codaraxis@gateway/vpn/mullvad/codaraxis] has quit [Remote host closed the connection] 11:10 -!- Codaraxis [Codaraxis@gateway/vpn/mullvad/codaraxis] has joined ##hplusroadmap 11:14 -!- c-c is now known as Cucko 11:15 -!- Cucko is now known as c-c 11:16 -!- Codaraxis_ [~Codaraxis@174.195.143.148] has joined ##hplusroadmap 11:16 -!- c-c is now known as C-C 11:17 -!- C-C is now known as O-O 11:19 -!- O-O is now known as B1 11:19 -!- B1 is now known as B] 11:19 -!- Codaraxis [Codaraxis@gateway/vpn/mullvad/codaraxis] has quit [Ping timeout: 240 seconds] 11:23 -!- B] is now known as B0 11:24 -!- Codaraxis_ [~Codaraxis@174.195.143.148] has quit [Remote host closed the connection] 11:24 -!- B0 is now known as O_O 11:24 -!- O_O is now known as OoO 11:24 -!- Codaraxis_ [~Codaraxis@148.sub-174-195-143.myvzw.com] has joined ##hplusroadmap 11:25 -!- OoO is now known as O0O 11:25 -!- O0O is now known as o-o 11:27 -!- o-o is now known as U_U 11:32 -!- U_U is now known as ^_^ 11:32 -!- ^_^ is now known as u_u 11:35 -!- u_u is now known as ^-^ 11:36 -!- ^-^ is now known as Guest50383 11:36 -!- Guest50383 is now known as U_U 11:42 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 11:44 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Client Quit] 11:47 -!- AESthetic256 [~AESthetic@13.68.109.2] has joined ##hplusroadmap 11:47 -!- AESthetic256 [~AESthetic@13.68.109.2] has quit [Client Quit] 11:49 -!- preview [~quassel@2407:7000:8423:b75:fd38:2845:cd81:1dcd] has quit [Ping timeout: 250 seconds] 11:52 -!- U_U is now known as ^O^ 11:52 -!- ^O^ is now known as U_U 11:55 -!- AESthetic256 [~AESthetic@40.123.48.12] has joined ##hplusroadmap 12:17 -!- Codaraxis_ [~Codaraxis@148.sub-174-195-143.myvzw.com] has quit [Read error: Connection reset by peer] 12:29 -!- sandeepkr_ [~sandeepkr@2a03:b0c0:2:d0::cac:7001] has quit [Read error: Connection reset by peer] 12:29 -!- kuldeep [~kuldeep@unaffiliated/kuldeepdhaka] has quit [Read error: Connection reset by peer] 13:04 -!- Codaraxis [~Codaraxis@2600:1012:b106:81f1:4d58:64e4:9ee:303a] has joined ##hplusroadmap 13:18 < superkuh> .tw https://www.nature.com/articles/ncomms11739 13:18 < EmmyNoether> working on party invite, wife getting nervous (@robhayes) 13:18 < superkuh> Wrong bot. 13:19 < superkuh> Anyway, paper about increasing the physical volume available for pluripotent mouse embryo cells too expand in to and how it causes increased access for the telomerase at that stage resulting in longer telomeres. Then a more recent paper about how this increases life span, https://www.nature.com/articles/s41467-019-12664-x 14:20 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 14:22 -!- helleshin [~talinck@98.29.27.253] has quit [Ping timeout: 240 seconds] 14:23 < kanzure> .title 14:23 < EmmyNoether> Mice with hyper-long telomeres show less metabolic aging and longer lifespans | Nature Communications 14:24 < kanzure> c-c: multi-virus resistance is real (most viruses require certain tRNAs to be implemented in the guest in order to convert it into a host) 14:31 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 14:35 -!- TC [~talinck@98.29.27.253] has joined ##hplusroadmap 14:35 -!- TC is now known as Guest13494 14:38 -!- hehelleshin [~talinck@98.29.27.253] has quit [Ping timeout: 240 seconds] 14:39 < U_U> kanzure: some virus resistance at best 14:56 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has quit [Ping timeout: 240 seconds] 14:58 -!- 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