--- Log opened Wed Nov 13 00:00:06 2019 00:42 -!- acertain [~acertain@unaffiliated/fread2281] has joined ##hplusroadmap 00:57 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Remote host closed the connection] 00:59 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 01:01 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has quit [Ping timeout: 240 seconds] 01:04 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 252 seconds] 01:09 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has joined ##hplusroadmap 01:14 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has quit [Ping timeout: 246 seconds] 01:17 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has joined ##hplusroadmap 01:19 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 01:24 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 276 seconds] 01:31 -!- Dr-G [~Dr-G@unaffiliated/dr-g] has quit [Ping timeout: 276 seconds] 01:39 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has quit [Ping timeout: 268 seconds] 01:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Read error: Connection reset by peer] 01:44 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has joined ##hplusroadmap 01:44 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 01:49 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 01:53 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has quit [Ping timeout: 240 seconds] 01:54 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 245 seconds] 01:56 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has joined ##hplusroadmap 02:38 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Remote host closed the connection] 02:48 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 02:52 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 246 seconds] 03:09 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has quit [Ping timeout: 268 seconds] 03:14 -!- EmmyNoether [~EmmyNoeth@oasys.ch0wn.org] has joined ##hplusroadmap 03:20 -!- N-time [~Mark@212.225.172.60] has joined ##hplusroadmap 03:23 -!- sachy [~sachy@78.108.102.220] has joined ##hplusroadmap 03:37 -!- N-time [~Mark@212.225.172.60] has quit [Quit: Leaving] 03:58 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 276 seconds] 04:29 -!- crockwork [~crockwork@66.205.193.158] has quit [Quit: crockwork] 04:33 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 04:38 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 250 seconds] 04:51 < archels> .title 1https://www.youtube.com/watch?v=hm4XK02dFlU 04:51 < EmmyNoether> URLError: (title:74) 04:51 < archels> .title https://www.youtube.com/watch?v=hm4XK02dFlU 04:52 < archels> hilarious use of stock footage here 04:52 < archels> actually it's rather sad 04:52 < archels> The Human Brain Project promo vid 04:52 < EmmyNoether> The Human Brain Project - YouTube 06:13 < jrayhawk> kanzure: has gnusha I/O been tolerable 06:18 < kanzure> haven't noticed anything lately 06:18 < jrayhawk> tank goodness 06:22 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 06:25 -!- helleshin [~talinck@98.29.27.253] has quit [Ping timeout: 265 seconds] 06:49 < kanzure> .title https://news.ycombinator.com/item?id=21521472 06:49 < EmmyNoether> More Intel speculative execution vulnerabilities | Hacker News 07:07 -!- mrdata_ [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap 07:09 -!- mrdata [~mrdata@unaffiliated/mrdata] has quit [Ping timeout: 246 seconds] 07:36 -!- yashgaroth [~ffffffff@2606:6000:ca84:b300:fcf4:2271:19bb:a42a] has joined ##hplusroadmap 08:12 < lsneff> archels: hbp seems very y confused unfortunately 08:23 -!- lewlz [~lewlz@cpe-107-15-246-163.nc.res.rr.com] has joined ##hplusroadmap 08:24 -!- lewlz [~lewlz@cpe-107-15-246-163.nc.res.rr.com] has quit [Remote host closed the connection] 08:24 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 08:31 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Remote host closed the connection] 08:31 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 08:33 -!- andytoshi [~apoelstra@wpsoftware.net] has joined ##hplusroadmap 08:33 -!- andytoshi [~apoelstra@wpsoftware.net] has quit [Changing host] 08:33 -!- andytoshi [~apoelstra@unaffiliated/andytoshi] has joined ##hplusroadmap 08:35 -!- Dr-G [~Dr-G@unaffiliated/dr-g] has joined ##hplusroadmap 08:46 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Remote host closed the connection] 08:46 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 08:47 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Remote host closed the connection] 08:47 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 08:52 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 250 seconds] 09:53 < lsneff> .wiki https://en.wikipedia.org/wiki/Holonomic_brain_theory 09:54 < kanzure> .wik 09:54 < EmmyNoether> "Community portal - Bulletin board, projects, resources and activities covering a wide range of Wikipedia areas. Help desk - Ask questions about using Wikipedia." - https://en.wikipedia.org/wiki/Main_Page 09:54 < lsneff> ah, thanks 09:54 < lsneff> lmao 09:54 < lsneff> "Holonomic brain theory is a branch of neuroscience investigating the idea that human consciousness is formed by quantum effects in or between brain cells." 09:55 < kanzure> .wik ribosome display 09:55 < EmmyNoether> "Ribosome display is a technique used to perform in vitro protein evolution to create proteins that can bind to a desired ligand. The process results in translated proteins that are associated with their mRNA progenitor which is used, as a complex, to bind to an immobilized [...]" - https://en.wikipedia.org/wiki/Ribosome_display 09:55 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 09:56 < kanzure> lsneff: sounds like quantum woo to me 09:56 < lsneff> Yeah, that was what I was thinking too 09:57 < lsneff> I'm not sure why the scientists in question think it's a valid theory of consciousness 09:57 < lsneff> kanzure: is there a doc with all the commands EmmyNoether can respond to? 09:57 < kanzure> .hel 09:57 < kanzure> .help 09:58 < kanzure> sending .help in pm will probably do the trick 09:58 < lsneff> thanks 09:58 < kanzure> nope nevermind 09:58 < kanzure> just bug nsh 10:00 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 245 seconds] 10:05 -!- sektor [~sektor@95.87.234.241] has joined ##hplusroadmap 10:07 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 252 seconds] 10:13 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 10:18 -!- sachy [~sachy@78.108.102.220] has quit [Quit: Leaving.] 10:35 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 11:28 -!- preview [~quassel@2407:7000:8423:b00::3] has joined ##hplusroadmap 11:44 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 11:49 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has joined ##hplusroadmap 12:09 < kanzure> .tw https://twitter.com/sigfig/status/1194333184332316673 12:09 < EmmyNoether> quote from a biology automation guy we're considering working with // "we have some hardware that requires windows xp drivers, so we run a vm, run the experiment, then intentionally crash the vm to get a core dump because that's the only way to get data out" (@sigfig) 12:38 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 12:42 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 250 seconds] 12:45 -!- mrdata_ is now known as mrdata 13:03 -!- faceface [~faceface@unaffiliated/faceface] has quit [Remote host closed the connection] 13:06 -!- ultimate_stupid [~glator@41.13.66.112] has joined ##hplusroadmap 13:10 -!- faceface [~faceface@unaffiliated/faceface] has joined ##hplusroadmap 13:12 < lsneff> that's absolutely horrifying 13:12 < kanzure> lsneff: lab life is awful https://www.youtube.com/watch?v=ovEghdXC4tE 13:27 -!- LeoTal [~Adium@58.170.86.79.rev.sfr.net] has quit [Quit: Leaving.] 13:30 -!- ultimate_stupid [~glator@41.13.66.112] has quit [Ping timeout: 240 seconds] 13:34 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 13:38 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Ping timeout: 246 seconds] 13:56 -!- HumanG33k [~HumanG33k@62.147.242.8] has quit [Read error: Connection reset by peer] 14:05 -!- spaceangel [~spaceange@ip-89-176-139-157.net.upcbroadband.cz] has quit [Ping timeout: 250 seconds] 14:13 < Dr-G> https://www.youtube.com/watch?v=a2tn8shf-mU 14:14 < Dr-G> Human nature crispr docu 14:15 < Dr-G> fuck the social justice warriors 14:17 < kanzure> that looks like an ad. is the full one out yet? 14:18 < Dr-G> any day now 14:18 < Dr-G> https://en.wikipedia.org/wiki/Human_Nature_(2019_film) 14:18 < kanzure> .wik human nature (2019 film) 14:19 < EmmyNoether> Sorry, wik took too long 14:23 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 14:35 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 14:38 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 14:48 -!- sektor [~sektor@95.87.234.241] has quit [Ping timeout: 246 seconds] 15:00 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 15:19 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 268 seconds] 15:26 -!- ciel_swarovski [54277024@84.39.112.36] has joined ##hplusroadmap 16:00 -!- not_you [~whaun@104.200.132.100] has joined ##hplusroadmap 16:11 < not_you> Greetings and/or salutations. New here. Been interested in anti-aging again recently. Saw a company called Libella licensed Sierra's AAV-hTERT gene therapy and is starting a few very small (5 person) trials in Columbia (believe you only need a hostpital IRB approval). They are charging participants $900k USD to participate! Think they are charging that because they can or high up-front costs? 16:13 < kanzure> trials cost a lot of money. $90k would more than cover synthesis of a retrovirus. 16:13 -!- N-time [~Mark@212.225.172.60] has joined ##hplusroadmap 16:21 < lsneff> biological immortality or digital immortality? 16:21 < not_you> $90k is still only 10% of the charge. 16:22 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 16:23 < lsneff> perhaps they're trying to recoup other costs 16:25 < Dr-G> Unnatural.Selection.S01E01.Cut.Paste.Life any good? 16:27 < not_you> Friend recommended it, said "we wil cure aging in 10 years, ?." I haven't seen it. 16:29 < kanzure> Dr-G: i'm in episode 2 16:29 < kanzure> around 22:23 i think 16:29 < Dr-G> looks promising so far 16:29 < Dr-G> im 5 mins in lel 17:03 < Dr-G> "regulate peoples garage" what this woman smoking 17:04 < Dr-G> oh the ticks, I think I've already seen that 17:04 < kanzure> anyone who spots me in the episode gets a cookie 17:05 < Dr-G> are you the tick on the mouse 17:06 < Dr-G> kanzure do you work in this field? 17:08 < kanzure> aw come on 17:08 < kanzure> Dr-G: https://www.technologyreview.com/s/612838/the-transhumanist-diy-designer-baby-funded-with-bitcoin/ 17:11 < Dr-G> nice 17:25 < lsneff> in an article about nectome: "I hope future people are appalled that in the 21st century, the richest and most comfortable people in history spent their money and resources trying to live forever on the backs of their descendants. I mean, it's a joke, right? They are cartoon bad guys." 17:25 < lsneff> I see where the quotation is coming from, but are people so shortsighted that they can't understand why digital immortality is a good thing? 17:28 < Dr-G> oh ya the odin packets are illegal in germoney anyway 17:29 < lsneff> It's not that only the rich people will live forever, it's everyone. 17:31 < Dr-G> This shouldn't even be an argument, the question is why do people refer randomness over science 17:31 < Dr-G> prefer 17:40 < lsneff> Dr-G: randomness? 17:42 < Dr-G> the randomness in making natural babies 17:43 < lsneff> right 17:43 < lsneff> playing god scares people 17:45 < kanzure> it's more that people have been conditioned to believe that having self-agency means playing god 17:48 < lewlz> lsneff: are you neff? 17:48 < lsneff> That's fair, it's not playing God, it's just evolution beyond the hand nature has dealt us 17:48 < lsneff> No 17:48 < lewlz> on efnet 17:48 < lsneff> nope 17:53 < kanzure> .title https://news.ycombinator.com/item?id=21530860 17:53 < EmmyNoether> John Carmack: I'm going to work on artificial general intelligence | Hacker News 17:53 -!- ciel_swarovski [54277024@84.39.112.36] has quit [Ping timeout: 260 seconds] 17:56 -!- soju [uid403160@gateway/web/irccloud.com/x-xbxryqnnquoemlev] has quit [Quit: Connection closed for inactivity] 18:02 -!- soju [uid403160@gateway/web/irccloud.com/x-ujnbswrsbuznqxph] has joined ##hplusroadmap 18:18 < not_you> Surprised there wasn't any discussion about applying this to human (a real human's, not cells) skin: https://med.stanford.edu/news/all-news/2015/01/telomere-extension-turns-back-aging-clock-in-cultured-cells.html 18:19 < kanzure> did you search the logs or is it just assumed that telomerase-modifying enzymes have never been discussed in here 18:20 < kanzure> er, telomere-modifying and telomerase-modifying 18:20 < kanzure> go make yourself a fusion protein https://diyhpl.us/wiki/gene-editing/ 18:21 < not_you> I meant by the paper's authors. But I will check the logs, thanks. 18:22 < lsneff> kanzure: wonder what carmack thinks he can do on his own 18:24 < lsneff> if anyone can make a difference by themself, it's carmack, but still 18:26 < kanzure> carmack had a low opinion of me when i was in high school: http://web.archive.org/web/20190306124317/http://www.quantumg.net/carmack_takes_bishop.php 18:26 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [] 18:29 < lsneff> wow, that's pretty crazy haha 18:31 < lsneff> I imagine you never ended up making an orbital scramjet? 18:31 < Dr-G> lol 18:32 < lsneff> It'd be interesting to explore whether the existence of molecular assemblers would lead to hardware following the same path as open-source software has. 18:33 < kanzure> ribosomes are molecular assemblers, next question 18:34 < lsneff> well no one's using ribosomes to build chunks of titanium 18:34 < kanzure> hmm 19:08 -!- adlai [~adlai@unaffiliated/adlai] has quit [Ping timeout: 240 seconds] 19:11 -!- N-time [~Mark@212.225.172.60] has quit [Ping timeout: 265 seconds] 19:22 -!- adlai [~adlai@unaffiliated/adlai] has joined ##hplusroadmap 19:32 < Dr-G> love how the commies always blame insurance companies, they dont know how insurance works 19:33 < lsneff> ^ oh boy, we've got a badass in here 19:33 < Dr-G> ! 19:34 < Dr-G> are you a commie lsneff 19:34 < lsneff> i am 19:35 < Dr-G> collectivism bad 19:36 * Dr-G slurps champagne 19:36 * lsneff slurps ubi 19:37 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has joined ##hplusroadmap 19:51 < Dr-G> excesseive champagne is killing my sperm quality 19:52 < lewlz> the lack of female company makes that statement moot 19:56 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:01 -!- LeoTal [~Adium@58.170.86.79.rev.sfr.net] has joined ##hplusroadmap 20:10 -!- lewlz [~lewlz@2606-a000-4806-e500-096b-5ce0-c501-764f.inf6.spectrum.com] has quit [Remote host closed the connection] 20:10 -!- not_you [~whaun@104.200.132.100] has quit [Ping timeout: 265 seconds] 20:12 -!- not_you [~whaun@104.200.132.239] has joined ##hplusroadmap 20:28 -!- lewlz [~lewlz@152.3.43.49] has joined ##hplusroadmap 20:33 -!- not_you [~whaun@104.200.132.239] has quit [Ping timeout: 265 seconds] 20:35 -!- not_you [~whaun@104.200.132.239] has joined ##hplusroadmap 20:36 -!- soju [uid403160@gateway/web/irccloud.com/x-ujnbswrsbuznqxph] has quit [Quit: Connection closed for inactivity] 20:36 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 20:52 < lsneff> speak for yourself 20:53 < lewlz> i am 20:54 -!- lewlz [~lewlz@152.3.43.49] has quit [Remote host closed the connection] 21:09 -!- lewlz [~lewlz@152.3.43.49] has joined ##hplusroadmap 21:19 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: drink and be refreshed] 21:28 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 21:40 -!- yashgaroth [~ffffffff@2606:6000:ca84:b300:fcf4:2271:19bb:a42a] has quit [Quit: Leaving] 21:42 -!- Dr-G [~Dr-G@unaffiliated/dr-g] has quit [Ping timeout: 246 seconds] 22:03 -!- not_you [~whaun@104.200.132.239] has quit [Quit: WeeChat 1.9.1] 22:28 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 276 seconds] 23:00 -!- bob_danger [bob_danger@gateway/vpn/mullvad/bobdanger/x-40535088] has joined ##hplusroadmap 23:00 -!- lewlz [~lewlz@152.3.43.49] has quit [Remote host closed the connection] 23:40 -!- preview [~quassel@2407:7000:8423:b00::3] has quit [Ping timeout: 250 seconds] --- Log closed Thu Nov 14 00:00:08 2019