--- Log opened Fri Feb 28 00:00:00 2020
--- Day changed Fri Feb 28 2020
00:00 < fenn> i for one liked cryptonomicon, and the rest of the books in the series: snow crash, diamond age
00:00 < fenn> the baroque cycle may also be in the same timeline but i haven't read that
00:11 -!- spaceangel [~spaceange@ip-89-177-23-46.net.upcbroadband.cz] has joined ##hplusroadmap
00:18 < fenn> "gee, sounds like I won't make money in a post-money system." haha, sad
00:18 < fenn> this is why we can't have nice things
00:33 < nsh> maaku, ask perhaps in #swhack re conlangs. i haven't dabbled really
00:34 < nsh> .t https://www.bbc.co.uk/news/science-environment-51669384
00:34 < saxo> Scientists detect biggest explosion since Big Bang - BBC News
00:56 -!- superjen96 [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has joined ##hplusroadmap
01:04 -!- superjen96 [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has quit [Ping timeout: 240 seconds]
01:41 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:7172:4493:da39:9e7a] has joined ##hplusroadmap
02:43 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:7172:4493:da39:9e7a] has quit []
03:14 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap
03:17 -!- Guest44183 [~talinck@98.29.27.253] has quit [Ping timeout: 240 seconds]
03:21 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap
04:16 -!- preview [~quassel@2407:7000:8423:b00::3] has quit [Ping timeout: 260 seconds]
04:19 < lsneff> I'd be interested in helping fund the vaccine project as well.
04:30 -!- Livestradamus [~quassel@unaffiliated/livestradamus] has quit [Quit: I'm out.]
04:30 -!- Livestradamus [~quassel@unaffiliated/livestradamus] has joined ##hplusroadmap
04:59 -!- spaceangel_ [~spaceange@ip-89-177-23-46.net.upcbroadband.cz] has joined ##hplusroadmap
05:00 -!- spaceangel [~spaceange@ip-89-177-23-46.net.upcbroadband.cz] has quit [Ping timeout: 240 seconds]
05:02 < lsneff> My university just released a statement about covid. Looks like they're ready to cancel all classes if necessary as a contingency.
06:16 < kanzure> i'm not going to take money from a student -_-
06:19 -!- Human_G33k [~HumanG33k@62.147.242.8] has joined ##hplusroadmap
06:22 -!- HumanG33k [~HumanG33k@62.147.242.8] has quit [Ping timeout: 260 seconds]
06:32 < lsneff> Haha, all right.
06:49 -!- bsm117532 [~bsm117532@unaffiliated/bsm117532] has joined ##hplusroadmap
07:10 -!- yashgaroth [~ffffffff@172.58.19.214] has joined ##hplusroadmap
07:32 -!- shmeebegek [6884015f@104.132.1.95] has joined ##hplusroadmap
08:13 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:7172:4493:da39:9e7a] has joined ##hplusroadmap
08:26 < kanzure> .tw https://twitter.com/RobertLKruse/status/1232109560132964358
08:26 < saxo> Curious if any Biohackers start circulating DNA to make mRNA vaccines against #COVID19. #Coronavirus genome available, information on design from SARS literature, can buy mRNA transcription kits. Data suggests naked SQ mRNA delivery works. Purity, dosing more complicated though. https://twitter.com/HelenBranswell/status/1232079998439317510 (@RobertLKruse)
08:47 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:7172:4493:da39:9e7a] has quit []
09:05 < yashgaroth> I barely trust biohackers with DNA purification and storage, much less RNA
09:05 < kanzure> your nucleases are offensive to my religion
09:06 < kanzure> actually don't even need nucleases to get RNA to mess up
09:12 < yashgaroth> just look at 'em funny
09:15 < yashgaroth> though in Moderna's case, when you raise 3.2 billion dollars it doesn't seem to matter if your platform works
09:26 < lsneff> Will distribution of a vaccine be possible without distributing production?
09:28 < kanzure> testing (and to a lesser extent distribution) will remain an exercise for the reader, although we'll definitely include some thoughts around that
09:53 < kanzure> .wik freeman dyson
09:53 < saxo> "Freeman John Dyson FRS (15 December 1923 – 28 February 2020) was an American theoretical physicist and mathematician, of British origin, known for his work in quantum electrodynamics, solid-state physics, astronomy and nuclear engineering." - https://en.wikipedia.org/wiki/Freeman_dyson
09:54 < kanzure> passed away today.
09:54 < shmeebegek> oh dang
09:56 < lsneff> He came up with the idea of dyson swarms. Rip
10:02 < shmeebegek> what a unique and free-thinking voice, they don't seem to make 'em like that anymore [in academia]
10:13 < maaku> There is a confirmed case of community-spread Covid-19 in northern california (vacaville)
10:13 -!- MarkOtaris [mark-otari@wikimedia/Mark-Otaris] has quit [Ping timeout: 240 seconds]
10:31 -!- fox2p [~fox2p@cpe-66-108-32-173.nyc.res.rr.com] has joined ##hplusroadmap
10:37 < lsneff> maaku: 11:41 <lsneff> Looks like covid broke quarantine in norcal
10:40 < maaku> looks like it's unrelated to quarantine efforts
10:40 < maaku> the woman sought medical help 2 days before the diamand princess passengers were brought back
10:40 < maaku> so proximity to travis afb is coincidental
10:40 -!- Codaraxis_ [Codaraxis@gateway/vpn/mullvad/codaraxis] has joined ##hplusroadmap
10:44 -!- Codaraxis [~Codaraxis@2600:8802:4200:1ca:7940:6cbe:2f80:986e] has quit [Ping timeout: 240 seconds]
10:53 < kanzure> interviews with freeman dyson https://www.youtube.com/playlist?list=PLVV0r6CmEsFzDA6mtmKQEgWfcIu49J4nN
11:07 < bsm117532> Super sad to hear about Dyson. I've spent waaaaay too long staring at his work. https://en.wikipedia.org/wiki/Schwinger%E2%80%93Dyson_equation
11:46 -!- fltrz [~fltrz@109.236.129.249] has quit [Ping timeout: 272 seconds]
11:51 < lsneff> https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf
11:53 < lsneff> Based on ^, 20% of all cases require hospitalization.
12:58 < kanzure> .tw https://twitter.com/unchainedcap/status/1233496143927091201
12:58 < saxo> A champion transcriber, bitcoin core developer and biohacker, @kanzure has it all. When he's not working to save the world, Bryan is busy working on the latest bitcoin protocol developments, saving the world. Don’t miss his talk on all the latest advancements in bitcoin tech. (@unchainedcap, in reply to tw:1233496142006149120)
13:50 < maaku> lsneff: that's the nightmare concern, not the death rate (which is over-estimated from lack of testing imo)
13:51 < maaku> if ICU units are swamped, the ~20% who need ventilation will be at the mercy of (at best) battlefield-quality medical care
14:02 < lsneff> Indeed, that's what I'm worried about.
14:17 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 258 seconds]
14:18 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
15:10 -!- spaceangel_ [~spaceange@ip-89-177-23-46.net.upcbroadband.cz] has quit [Ping timeout: 252 seconds]
15:29 < bsm117532> Those falling rates of infection in the WHO report are really encouraging, I think...
15:35 < yashgaroth> the 20% hospitalization rate is only in laboratory-confirmed cases, per that report? and lab testing is usually reserved for the most severe cases, plus a lot of those numbers rely on Chinese data which is almost worthless
15:50 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:185e:d626:ae85:68f0] has joined ##hplusroadmap
16:00 < maaku> yashgaroth: I think that is correct
16:00 < lsneff> Hopefully... I guess we'll see in a few weeks.
16:31 -!- N-time [~Mark@212.225.172.60] has joined ##hplusroadmap
16:52 < lsneff> I think one could make the case that it's underestimated as well.
18:27 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: HUMAN ERROR]
18:27 -!- MarkOtaris [mark-otari@wikimedia/Mark-Otaris] has joined ##hplusroadmap
18:32 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:185e:d626:ae85:68f0] has quit [Remote host closed the connection]
18:37 -!- fltrz [~fltrz@109.236.129.249] has joined ##hplusroadmap
18:51 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
18:54 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 255 seconds]
19:00 < kanzure> nmz787: "corona discharge" is pretty disgusting and gross, i like it
19:06 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap
19:16 -!- N-time [~Mark@212.225.172.60] has quit [Quit: Leaving]
19:18 < lsneff> As a name?
19:19 < kanzure> yeah.
19:19 < kanzure> i am going to need to find someone to hand this off to since i'm a little busy
19:19 < lsneff> I think making a play of the beer would be fun.
19:20 < lsneff> CoronaBurn, playing off corona light
19:32 < heath> .title https://www.fool.com/investing/2019/07/17/the-multibillion-dollar-race-for-gene-therapy-manu.aspx
19:32 < saxo> The Multibillion-Dollar Race for Gene Therapy Manufacturing Is On | The Motley Fool
19:51 -!- mrdata_ [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap
19:53 -!- mrdata [~mrdata@unaffiliated/mrdata] has quit [Ping timeout: 258 seconds]
21:03 -!- mrdata_ is now known as mrdata
21:06 -!- yashgaroth [~ffffffff@172.58.19.214] has quit [Quit: Leaving]
21:17 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 246 seconds]
22:46 < fenn> coronerous
--- Log closed Sat Feb 29 00:00:09 2020