--- Log opened Sun Apr 25 00:00:36 2021 00:37 < fenn> someone compared the "leaky vaccine" to breeding a lethal strain of marek's disease 00:37 < fenn> .wik marek's disease 00:37 < saxo> "Marek's disease is a highly contagious viral neoplastic disease in chickens. It is named after József Marek, a Hungarian veterinarian." - https://en.wikipedia.org/wiki/Marek%27s_disease 00:37 < fenn> i couldn't come up with a good argument for why it was different 00:39 < fenn> maybe it's not as leaky? 02:23 -!- spaceangel [~spaceange@ip-86-49-112-179.net.upcbroadband.cz] has joined ##hplusroadmap 03:49 < streety> seems comparable to antibiotic resistance as well 04:00 < fenn> except antibiotic resistant bacteria are not inherently more lethal 04:01 < fenn> sometimes they acquire virulence genes using the cassette gene transfer mechanism, but it's not intrinsic to the process 04:11 < streety> comparable might be too strong. I was thinking more that a solution that is incomplete or imperfectly applied leads to unforeseen difficulties 04:30 -!- thedragon [~thedragon@141.98.255.151] has joined ##hplusroadmap 04:32 -!- darsie [~kvirc@84-113-55-200.cable.dynamic.surfer.at] has joined ##hplusroadmap 06:05 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0:292a:c67c:3cfd:1033] has joined ##hplusroadmap 08:37 < kanzure> "Rationally designed base editors for precise editing of the sickle cell disease mutation" https://www.liebertpub.com/doi/10.1089/crispr.2020.0144 09:08 -!- spaceangel [~spaceange@ip-86-49-112-179.net.upcbroadband.cz] has quit [Ping timeout: 260 seconds] 09:08 -!- spaceangel_ [~spaceange@ip-86-49-112-179.net.upcbroadband.cz] has joined ##hplusroadmap 09:09 < kanzure> https://www.genengnews.com/insights/inlaid-base-editors-slide-windows-increase-efficiency/ 09:27 < kanzure> .title https://news.ycombinator.com/item?id=26929370 09:27 < saxo> Show HN: Verilog2factorio | Hacker News 09:28 < kanzure> https://github.com/Redcrafter/verilog2factorio/ 10:12 -!- Jay_Dugger [~jwd@47.185.203.87] has joined ##hplusroadmap 11:49 < kanzure> https://www.chiaexplorer.com/charts/netspace 11:50 < kanzure> hard drive shortage incoming 12:40 < kanzure> .title https://news.ycombinator.com/item?id=26931244 12:40 < saxo> Cisco says computer chip shortage to last six months | Hacker News 12:56 < Jay_Dugger> Hello, everyone. 12:57 < kanzure> Jay_Dugger: greetings 13:57 < kanzure> https://chiapower.org/ 15:19 -!- spaceangel_ [~spaceange@ip-86-49-112-179.net.upcbroadband.cz] has quit [Remote host closed the connection] 15:48 < fenn> .title 15:48 < saxo> Chia Power - Estimate of total energy consumption in the Chia network 15:54 < fenn> is chia going to eat up the cheap drives or the expensive drives that use the least power per bit stored? 15:59 < kanzure> dunno 16:56 -!- thedragon [~thedragon@141.98.255.151] has quit [Quit: Leaving] 18:01 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0:292a:c67c:3cfd:1033] has quit [Quit: Leaving] 19:08 -!- Sir_Alexei [uid348072@gateway/web/irccloud.com/x-cqrwqaritzwmonhq] has joined ##hplusroadmap 19:44 -!- Malvolio is now known as UUUV 20:25 -!- beag [~beagg@2804:d49:4923:a300:8d68:328d:f0e2:b93a] has joined ##hplusroadmap 20:40 -!- beag [~beagg@2804:d49:4923:a300:8d68:328d:f0e2:b93a] has quit [Quit: Leaving] 20:43 -!- darsie [~kvirc@84-113-55-200.cable.dynamic.surfer.at] has quit [Ping timeout: 252 seconds] 21:03 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 21:05 -!- Sir_Alexei [uid348072@gateway/web/irccloud.com/x-cqrwqaritzwmonhq] has quit [] --- Log closed Mon Apr 26 00:00:37 2021