--- Log opened Sat Jun 26 00:00:48 2021 01:01 < maaku> kanzure: the weird anime movie? yes 02:45 -!- Urchin[emacs] [~user@user/urchin] has quit [Ping timeout: 252 seconds] 02:54 -!- Codaraxis_ [~Codaraxis@ip68-5-90-227.oc.oc.cox.net] has joined #hplusroadmap 02:58 -!- Codaraxis__ [~Codaraxis@193.32.126.161] has quit [Ping timeout: 265 seconds] 03:05 -!- Codaraxis__ [~Codaraxis@193.32.126.154] has joined #hplusroadmap 03:08 -!- Codaraxis_ [~Codaraxis@ip68-5-90-227.oc.oc.cox.net] has quit [Ping timeout: 244 seconds] 04:58 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0:44bc:47a7:36fd:5a] has joined #hplusroadmap 05:43 -!- Urchin[emacs] [~user@user/urchin] has joined #hplusroadmap 05:44 < fenn> https://tickrepellent.net/why-are-there-more-ticks/#:~:text=Climate%20Change%20and%20Ticks 05:46 < L29Ah> because hummies don't kill their natural hosts 05:46 < fenn> deer and mice? 05:47 < L29Ah> deer, yes; ok, didn't know mice are also affected, as they're quite agile and sensitive 05:47 < fenn> seems like their natural hosts are just about everything 05:48 < L29Ah> everything big used to be human food 05:48 < fenn> bring back the wolf 05:48 < L29Ah> and now you can't just shoot a deer you see in a forest 07:04 < fenn> http://newatlas.com/tick-rover-robot/28410/ 07:10 < L29Ah> CO2 huh 07:10 < L29Ah> i wonder if they tried to warm up the cloth 07:11 < fenn> seems better to put some dry ice on the rover than dragging tubes everywhere 07:13 < fenn> finally a use for RC cars :D 07:16 < fenn> i wonder why there aren't chewable tick repellents for humans 07:18 < fenn> "because we bathe more regularly than dogs do" 07:26 < L29Ah> chewable? do you mean edible? 07:26 < fenn> yeah. the bathing thing was about once a month application 07:27 < L29Ah> i'm pissed that the best insect repellent substance on the market that is suitable for topical use on humans dissolves spandex 07:28 < fenn> how about picaridin. supposedly it lasts 12 hours vs 2-5 for DEET (against ticks) 07:29 < fenn> it seems repellents are divided into "things applied to skin" and "things applied to clothing and gear" 07:29 < L29Ah> i'm yet to find a formulation of picaridin that doesn't contain DEET, but it's probably okay 07:37 -!- catalase_ [~catalase@user/catalase] has quit [Ping timeout: 265 seconds] 10:06 -!- Codaraxis [~Codaraxis@user/codaraxis] has joined #hplusroadmap 10:09 -!- Codaraxis__ [~Codaraxis@193.32.126.154] has quit [Ping timeout: 268 seconds] 10:28 -!- GeDaMo [~GeDaMo@user/gedamo] has joined #hplusroadmap 10:31 -!- trn [jhj@2600:3c00::f03c:92ff:feb2:b9ef] has quit [Ping timeout: 272 seconds] 12:16 < kanzure> "Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging" https://advances.sciencemag.org/content/7/26/eabg6082 12:16 < kanzure> "The notion that the germ line does not age goes back to the 19th-century ideas of August Weismann. However, being metabolically active, the germ line accumulates damage and other changes over time, i.e., it ages. For new life to begin in the same young state, the germ line must be rejuvenated in the offspring. Here, we developed a multi-tissue epigenetic clock and applied it, together with ... 12:16 < kanzure> ...other aging clocks, to track changes in biological age during mouse and human prenatal development. This analysis revealed a significant decrease in biological age, i.e., rejuvenation, during early stages of embryogenesis, followed by an increase in later stages. We further found that pluripotent stem cells do not age even after extensive passaging and that the examined epigenetic age dynamics ... 12:16 < kanzure> ...is conserved across species. Overall, this study uncovers a natural rejuvenation event during embryogenesis and suggests that the minimal biological age (ground zero) marks the beginning of organismal aging." 12:19 < fenn> "pluripotent stem cells do not age" sounds highly convenient 12:21 < fenn> guh stupid websites these days. 12:22 < fenn> https://advances.sciencemag.org/content/advances/7/26/eabg6082.full.pdf ^above paper in pdf form 12:47 < L29Ah> so can we just say that cell division and growth brings rejuvenation? 12:47 < L29Ah> just by dilution of garbage in newly produced pristine stuff 12:50 < L29Ah> alright, nvm, read into the actual paper, and it seems like i should read into the markers they used 12:59 < fenn> i think epigenetics is only half the story 12:59 < fenn> if you learn anything interesting from the paper, please share 13:32 -!- GeDaMo [~GeDaMo@user/gedamo] has quit [Quit: Leaving.] 17:09 -!- balrog [znc@user/balrog] has quit [Quit: Bye] 17:16 -!- balrog [znc@user/balrog] has joined #hplusroadmap 18:13 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0:44bc:47a7:36fd:5a] has quit [Quit: Leaving] 20:30 < lsneff> What's the current state-of-the-art in artificial muscle? 20:35 < mrdata> shape memory alloy (muscle wire) isnt so terrible but i am not sure 20:54 < fenn> ray baughmann coiled monofilament is pretty good 20:54 < fenn> electrostatic carbon fiber actuators are ludicrous power to weight ratio but require high voltages 20:56 < fenn> i have a fondness for mckibben actuators (festo fluidic muscle, a rubber tube in a braided cable sleeve, and so on) 22:01 -!- GeDaMo [~GeDaMo@user/gedamo] has joined #hplusroadmap 22:29 < mrdata> neat 22:41 < fenn> for the lazy http://en.wikipedia.org/wiki/Pneumatic_artificial_muscles --- Log closed Sun Jun 27 00:00:49 2021