--- Log opened Sat Dec 18 00:00:04 2021
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14:01 < kanzure> https://www.anti-agingfirewalls.com/2021/12/17/online-presentation
14:08 < kanzure> "Reversing age: dual species measurement of epigenetic age with a single clock" https://www.biorxiv.org/content/10.1101/2020.05.07.082917v1
14:09 < kanzure> "Universal DNA methylation age across mammalian tissues" https://www.biorxiv.org/content/10.1101/2021.01.18.426733v1
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14:11 < kanzure> (the katcher stuff) https://joshmitteldorf.scienceblog.com/2020/05/11/age-reduction-breakthrough/
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23:28  * adlai had an interesting start-of-conversation, last week, about cryopreservation
23:28 < adlai> I'm a bit surprised at how excited so many people are, before they realize that you need to sign a contract with conditions for thawing
23:30 < adlai> taken to an extreme, that problem boils down to "do you agree that this list describes reasonable conditions for life, liberty, and the avoidance of having to be refrozen every few decades while we work out the kinks in true life-extension? yes/no"
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23:32 < adlai> the interlocutor seemed to default to optimism, where the response to unknown conditions is "thaw me and ask", although this has costs: both the expense of the thawing process, and the risks of failure
23:34 < adlai> I guess I'm still a 'deathist'; at least, I definitely don't view the state of being cryopreserved as being alive in any way.
23:35 < adlai> however, the legal requirement that clients be medically dead before the process begins is probably still a little iffy; it both delays research, and creates a strange incentive where the cryopreservation industry eats hospice care.
23:38 < adlai> from my highly uneducated statistical armchair, it seems that biological aging is still a good thing; it prevents the human swarm from ossifying too rapidly. maybe I simply lack faith in humans.
23:39 < adlai> btw, is there any consensus about the use of the 8th bit in the character encoding, specifically in this IRC channel?
23:41 < adlai> I realize that Progress, the personified enemy of Hope, will crush the ASCII character set, along with the skulls of John Connor and anyone who tries to help him; however, it is a nuisance to see discussions of the ?-calculus and wonder whether that could yet be any letter other than lambda.
23:43 < adlai> muurkha: a few years ago I found a printed copy of CLtL2; it has a sentence in the inside cover that is a good example of natural language overflowing the 21st century human stack.
23:44 < adlai> Common Lisp is quite far from the lambda calculus, although your comment about unreadability reminded me of that; even written and published natural language can be inscrutable when it presumed an attention span greater by an order of magnitude than that available to the eventual audience.
23:44 < adlai> [the original quote is from one of the Federalist papers]
23:54 < adlai> ... I guess "Federalist Papers" is also an indirection to search engines for anyone who hasn't studied the American Revolution; they were a bunch of articles written by a pseudonym in the 18th century to encourage revolt in the colonies. their use of the English Language is similar to that found in the US Constitution, i.e., what you'd find split into an internet paragraph these days would be just a few
23:54 < adlai> clauses in a giant sentence.
--- Log closed Sun Dec 19 00:00:05 2021