--- Log opened Wed Jan 19 00:00:34 2022 00:01 < nmz787> https://www.cell.com/action/showPdf?pii=S1097-2765%2821%2900169-6 00:02 < nmz787> .title https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00169-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276521001696%3Fshowall%3Dtrue# 00:02 < saxo> DEFINE_ME 00:02 < nmz787> .title https://doi.org/10.1016/j.molcel.2021.03.001 00:02 < saxo> Redirecting 00:02 < nmz787> "ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system" 00:03 < nmz787> anyway, just some TEM images of organelles 01:14 -!- Codaraxis [~Codaraxis@user/codaraxis] has joined #hplusroadmap 01:45 -!- johest [~johest@69-64-178-143.ftth.glasoperator.nl] has joined #hplusroadmap 01:45 -!- johest [~johest@69-64-178-143.ftth.glasoperator.nl] has quit [Changing host] 01:45 -!- johest [~johest@user/johest] has joined #hplusroadmap 01:50 -!- johest [~johest@user/johest] has quit [Quit: The Lounge - https://thelounge.chat] 01:52 -!- johest [~johest@69-64-178-143.ftth.glasoperator.nl] has joined #hplusroadmap 01:52 -!- johest [~johest@69-64-178-143.ftth.glasoperator.nl] has quit [Changing host] 01:52 -!- johest [~johest@user/johest] has joined #hplusroadmap 02:18 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has joined #hplusroadmap 02:21 -!- spaceangel [~spaceange@ip-78-102-216-202.net.upcbroadband.cz] has joined #hplusroadmap 02:21 -!- Codaraxis [~Codaraxis@user/codaraxis] has quit [Ping timeout: 256 seconds] 02:56 -!- Codaraxis [~Codaraxis@user/codaraxis] has joined #hplusroadmap 02:57 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has quit [Ping timeout: 240 seconds] 03:09 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has joined #hplusroadmap 03:10 < maaku> lsneff: what's the best approach to doing a concurrent web server in rust? the iron crate? 03:12 -!- Codaraxis [~Codaraxis@user/codaraxis] has quit [Ping timeout: 268 seconds] 04:50 -!- gnusha [~gnusha@user/gnusha] has joined #hplusroadmap 04:50 -!- Topic for #hplusroadmap: biohacking, nootropics, transhumanism, open hardware | pardon the dust | this channel is LOGGED: http://gnusha.org/logs | https://diyhpl.us/wiki | not quite sponsored by george church | banned by the MIT media lab and the FDA 04:50 -!- Topic set by fenn [~fenn@user/fenn] [Wed May 19 15:37:47 2021] 04:50 [Users #hplusroadmap] 04:50 [@ChanServ ] [ chiastre ] [ fenn ] [ kanzure ] [ otoburb ] [ sivoais ] 04:50 [ ^ditto ] [ Codaraxis_ ] [ gnusha ] [ L29Ah ] [ pasky ] [ sknebel ] 04:50 [ _flood ] [ cpopell ] [ greenz1[m]] [ livestradamus] [ potatope ] [ soundand1ury] 04:50 [ acertain ] [ Croran ] [ heath ] [ lsneff ] [ ptrcmd ] [ spaceangel ] 04:50 [ andytoshi] [ deltab_ ] [ helleshin ] [ maaku ] [ redlegion ] [ srk ] 04:50 [ archels_ ] [ docl ] [ Hooloovoo ] [ Malvolio ] [ rndhouse[m]] [ strages ] 04:50 [ balrog ] [ dr-orlovsky] [ HumanG33k ] [ mgxm ] [ RubenSomsen] [ streety ] 04:50 [ berndj ] [ dustinm ] [ Jenda ] [ mrdata ] [ s0ph1a ] [ superkuh ] 04:50 [ catalase ] [ EnabrinTain] [ johest ] [ muurkha ] [ saxo ] [ TMA ] 04:50 [ catern ] [ faceface ] [ jrayhawk_ ] [ nmz787_ ] [ SDr ] [ xaete[m]1 ] 04:50 [ cc0 ] [ FelixWeis ] [ juri_ ] [ nsh ] [ sgiath ] [ yuanti ] 04:50 -!- Irssi: #hplusroadmap: Total of 66 nicks [1 ops, 0 halfops, 0 voices, 65 normal] 04:50 -!- mode/#hplusroadmap [+v gnusha] by ChanServ 04:50 -!- Channel #hplusroadmap created Wed May 19 06:51:36 2021 04:51 -!- fltrz [~ik@94.105.125.89.dyn.edpnet.net] has joined #hplusroadmap 04:52 -!- Irssi: Join to #hplusroadmap was synced in 128 secs 04:59 < lsneff> Probably rocket, actix web, warp, or tide 04:59 < lsneff> https://www.arewewebyet.org/ 05:01 < lsneff> Keep in mind that a single-threaded server written in rust can probably serve hundreds of thousands of requests per second, even without being multithreaded 05:03 < L29Ah> sock.accept().close() ← serving hundreds of thousands of requests per second 05:05 < L29Ah> also manual poll/epoll/select fucketry is a boring royal PITA so (green) multithreading is a must for a (loaded) server 05:23 < lsneff> Yep, rust supports ‘green’ threads quite well 05:25 < L29Ah> does it? last time i checked you had to use a separate green thread framework, and the only I/O you could do w/o breaking green threads model was via few libraries written for the framework 05:32 < lsneff> Async is integrated into the language. You need to use one of a number of libraries to run async tasks and asynchronously do IO 06:28 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0::f2f0] has joined #hplusroadmap 07:58 -!- Malvolio [~Malvolio@user/malvolio] has quit [Ping timeout: 256 seconds] 08:53 < kanzure> "the Third International Summit on Human Genome Editing has been postponed from March 7-9, 2022 to March 6-8, 2023." 09:16 < nmz787_> at least they didn't call it the "annual international summit on human genome editing" 09:19 < nmz787_> .wik hobby tunneling 09:19 < saxo> "Hobby tunneling is tunnel construction as a diversion. Usually, hobby tunnelers dig their tunnels by hand, using little equipment, and some can spend years or even decades to achieve any degree of completion." - https://en.wikipedia.org/wiki/Hobby_tunneling 10:15 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has quit [Ping timeout: 250 seconds] 10:24 < maaku> nmz787_: https://en.wikipedia.org/wiki/William_Lyttle 11:02 -!- Malvolio [~Malvolio@user/malvolio] has joined #hplusroadmap 11:42 -!- Codaraxis [~Codaraxis@user/codaraxis] has joined #hplusroadmap 11:42 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has joined #hplusroadmap 11:44 < nmz787_> .wik william lyttle 11:44 < saxo> Article not found: https://en.wikipedia.org/wiki/William_lyttle gave 404 | Searched en for 'william lyttle' | https://en.wikipedia.org/wiki/No_result_found gave 404 | Searched en for 'No result found' 11:44 < nmz787_> .wik william_lyttle 11:44 < saxo> Article not found: https://en.wikipedia.org/wiki/William_lyttle gave 404 | Searched en for 'william lyttle' | https://en.wikipedia.org/wiki/No_result_found gave 404 | Searched en for 'No result found' 11:44 -!- Codaraxis__ [~Codaraxis@user/codaraxis] has joined #hplusroadmap 11:46 < kanzure> ? 11:46 -!- Codaraxis [~Codaraxis@user/codaraxis] has quit [Ping timeout: 256 seconds] 11:47 < nmz787_> lol 11:47 < nmz787_> "being rehoused in an apartment in a high-rise building. He was put on the top floor, to discourage tunnelling" 11:47 -!- Codaraxis_ [~Codaraxis@user/codaraxis] has quit [Ping timeout: 256 seconds] 11:47 < nmz787_> "While there he knocked a hole in a dividing wall between two rooms" 11:54 < muurkha> what a shame :( 11:54 < muurkha> couldn't they just rent him a dump truck? 11:55 < kanzure> city should drop off some tools and an excavator and tell him to help out on the subways 11:59 < muurkha> instead they condemn him to terrafoam 12:09 < nmz787_> .title https://www.youtube.com/watch?v=9IqxPCgaRIQ&list=PLeW1zs6nLUKEDbo8vJMmHpEuB-z-P1wyA 12:09 < saxo> OpenAccess Overview - YouTube 12:09 < nmz787_> Silicon CAD scripting 15:20 -!- Codaraxis__ [~Codaraxis@user/codaraxis] has quit [Ping timeout: 256 seconds] 15:48 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0::f2f0] has quit [Quit: Leaving] 16:42 -!- spaceangel [~spaceange@ip-78-102-216-202.net.upcbroadband.cz] has quit [Remote host closed the connection] 18:01 < fltrz> do we have accurate tomographic slice images of the organ of corti? inner, outer hair cells, pillars, ... ? 19:48 -!- RawFiend [~rawfiend@31.155.242.167] has joined #hplusroadmap 21:43 -!- RawFiend [~rawfiend@31.155.242.167] has quit [Remote host closed the connection] 22:07 -!- faceface [~faceface@user/faceface] has quit [Remote host closed the connection] --- Log closed Thu Jan 20 00:00:35 2022