--- Log opened Mon May 27 00:00:07 2024
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04:53 < hprmbridge> soul_syrup> @fennfoot thanks for the nice links! I'll be adding this info to our library of methods
04:54 < hprmbridge> soul_syrup> Thanks! We won't be having any off-site needs, schooling will be in our community
04:55 < hprmbridge> soul_syrup> And yea fulltime
05:09 < hprmbridge> soul_syrup> I read the post on amarna and it seems like OP is just giving a lot of shallow opinions
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06:21 < jrayhawk> Letting dentists convince you that dental plaque is inherently pathological is like letting surgeons convince you that having an appendix is inherently pathological.
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06:30 < hprmbridge> soul_syrup> dont let dentists fool you, theyre like car mechanics in a lot of ways lol
06:35 < hprmbridge> soul_syrup> I snus loose tobacco daily(homemade simple ingredients), brush my teeth in the morning only, with some simple carbon non flouride toothpaste with some other natural ingredients daily, floss daily, gargle cheap vodka at night, never had a cavity, never any mouth problems, but I do put baking soda in my snus so that may have helped, could it have something to do with high amount of fermented
06:35 < hprmbridge> soul_syrup> vegetables and yogurts/kvargs/skyrs
06:36 < hprmbridge> soul_syrup> been to the dentist like 4 times in my life
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08:15 < hprmbridge> kanzure> "Development of multiplexed orthogonal base editor (MOBE) systems" https://www.nature.com/articles/s41587-024-02240-0
08:22 < hprmbridge> pinkbearer> how so
08:40 < jrayhawk> It is only as pathological as the bacteria that inhabit it.
08:41 < jrayhawk> And the metabolic and immunological context they're placed in.
08:47 < jrayhawk> A reservoir of pathological bacteria creates a more robust pathology. A reservoire of healthy bacteria creates a more robust health.
08:48 < jrayhawk> er, s/reservoire/reservoir/
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14:08 < fenn> .m https://x.com/internetarchive/status/1795117949499445554
14:08 < AugustaAva> ​twitter: <internetarchive> Sorry to say, http://archive.org is under a ddos attack. The data is not affected, but most services are unavailable. ␤  ␤ We are working on it. This thread will have updates.
14:09 < fenn> everything's broken :(
14:12 < pasky> I'm finally reading the diamond age and damn, the illustrated primer is a perfect llm application .. not sure if not possible already
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14:19 < fenn> hi pasky. are you keeping up with the AI flood?
14:20 < fenn> the illustrated primer not only has interactive storytelling, it's also a physics simulation
14:20 < fenn> at that point i don't think we can call it a "language model"
14:20 < fenn> i'm sticking with "AI" because all the distinctions seem meaningless
14:20 < pasky> hm i'm still in a third of the book (at the dinosaur story), so probably still missing a lot, ok
14:21 < pasky> fenn: moderately
16:06 < hprmbridge> Eli> Looks like Minicircle is going after a much bigger market. Cancer patients, low T males, etc ...
16:06 < hprmbridge> Eli> Trying to get approved in multiple countries like Japan, etc ... Dave Asprey has a form on his site where I'm assuming he's getting a kickback for selling $25,000 minicircle therapies https://cdn.discordapp.com/attachments/1064664282450628710/1244788814564823071/image.png?ex=6656636c&is=665511ec&hm=38948046c90af3779c50401f0bb0f0fc1173b195ee09a5e55307f74f5a8ca871&
16:09 < hprmbridge> Eli> FSH and low T are one thing. But I have to imagine if they start to try selling this to cancer patients that could be when Senators or the FDA steps in. Regardless, of jurisdiction.
16:11 < hprmbridge> Eli> If minicircle ends up being another theranos, I feel like there will be a major sea change in biohacker influencers and regulation. There's so many people and government organizations piling up on this therapy now. Multiple countries that want to use Minicircle.
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18:52 < hprmbridge> Eli> I might be speaking to Patri Friedmn irl tomorrow. Anyone have opinions on what I should say? I want to stay humble, but maybe mention that if this is a Therano situation then he is just going to be making the argument that statists should have power.
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19:45 < hprmbridge> alonzoc> Yeah expressing a general worry that minicircle is potentially providing ammunition to interests which want to expand government powers is a good approach I think. The knee jerk reaction to any public outcry by governments is to extend the scope of their powers and then after they've had them for a while it becomes heretical to question the need for government involvement
19:47 < hprmbridge> alonzoc> We've also already got the US government talking about regulating DNA printing to protect us from bioweapons. Less fuel on the "let's regulate the technology to keep people 'safe'" fire the better
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22:43 < jrayhawk> max has already talked to patri on several occasions about the biological implausibility
22:43 < jrayhawk> so don't waste your time on the biology angle
23:09 < hprmbridge> Eli> ok, I knew he had spoken to him. I didn't realize the conversations were in depth. I think if I get time with him I'll just stick to the concerned about the libertarian movement angle. It's basically clickbait if a libertarian island seems like it needs parental guidance.
23:21 < NewtonTrendy> https://pastebin.com/Fr5L5MTu
--- Log closed Tue May 28 00:00:08 2024