--- Log opened Sat Jun 22 00:00:31 2024
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04:55 < NewtonTrendy> is there a sarcasm day?
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06:13 < ike8> everyday
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11:48 < TMA> NewtonTrendy: International Sarcasm Day is reportedly January 5th, while National Sarcasm Day is December 10th
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13:53 < NewtonTrendy> nice
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18:20 < fenn> the peplica patent was very long and obfuscated so i had claude read it for me instead: https://fennetic.net/irc/protein_reverse_translation_peplica_explained_by_claude.html
18:27 < hprmbridge> kanzure> cool
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18:49 < hprmbridge> Eli> Pretty fascinating update on klotho, platelet factor 4, and it’s relationship to exercise and cognitive enhancement. I will need to read some of the papers, but seems like an area that should receive some funding. https://youtu.be/qsA5MBLoeGI?si=hnaTEoJ7bWpesYIN
18:52 < hprmbridge> Eli> Using Mendelian randomization, people with a kotho mutation seem to be protected from apoe4 issues. While correlation is not causation, they’ve done a number of mice studies and even a monkey study to better understand dose response and some of the biochemical pathways involved.
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--- Log closed Sun Jun 23 00:00:32 2024