--- Log opened Wed Jun 26 00:00:35 2024
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08:33 < hprmbridge> kanzure> RNA-guided recombinases https://twitter.com/pdhsu/status/1805981296276955571
09:54 < NT^> https://github.com/abb128/LiveCaptions
09:57 < NT^> CPU
10:33 < jrayhawk> win 11
10:33 < jrayhawk> whoops
10:35 < hprmbridge> kanzure> win all
10:36 < jrayhawk> i will settle for less
10:57 < pasky> hm seems like i'll have to write my own claude vim plugin to get something reasonably powerful
11:13 < pasky> https://github.com/paul-gauthier/aider seems like closest to what I want to aim for (But still very far from it)
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11:28 < hprmbridge> kanzure> ask claude to write the plugin.
12:28 < L29Ah> not sure if trolling
13:08 < TMA> my experience with llms generating code is really bad. the code looks plausible but the called api does not exist, it does not perform the task or other such failure.
13:12 < hprmbridge> kanzure> ask it to improve your prompt. you're not thinking 9000th dimensionally.
13:17  * TMA is not thinking at all. it is just some electrochemical reaction in a small blob composed mostly of H,C,O,N
13:19 < TMA> maybe my failure is by insisting on a language different from python
13:19 < TMA> *is in
13:22 < TMA> It's just that I irrationally hate python.
13:37 < hprmbridge> jason.crawford> The Roots of Progress Institute is hosting our first annual progress conference, together with Foresight and some other great orgs. Oct 18–19 in Berkeley, CA: https://rootsofprogress.org/conference
13:48 < hprmbridge> kanzure> cool, but is berkeley really the root of progress
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14:30 < pasky> kanzure: this is *definitely* what i'm gonna do, ofc
14:30 < pasky> TMA: claude 3.5 hits different, tbh (it's not perfect but it's a lot better than anything i tried before)
14:30 < pasky> also, what the hell?
14:31 < pasky> 23:28 < Mrkva> Muaddib_: Mn M pmlr ahs u wrew rqtdaxwri cmwf duqihv vhqhugxfuzrwmtug yszwmwswmhq, cmgg ahs zr uzgr wh wrgg  vr u duqihv "ahsd vuvu" ohbr?
14:31 < pasky> 23:28 < Muaddib_> Mrkva: Sure, here's your random "your mama" joke: Your mama's so encrypted, even the NSA calls her for decryption advice.
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15:51 < hprmbridge> Eli> @Jrayhawk who is your favorite health science communicator if not Attia? I saw you posted Masterjohn videos
15:52 < jrayhawk> He's the best on heart disease I have come across, but he neglects adhesion and permeability
15:53 < jrayhawk> possibly under a "more wood behind fewer arrows" messaging strategy; not sure
15:53 < hprmbridge> Eli> Chatgpt?
15:54 < hprmbridge> Eli> I am curious if the AMA is putting pressure on chatgpt medical research responses. So much of medicine is doctors forming mafias to subjugate others opinions
16:01 < jrayhawk> https://www.youtube.com/watch?v=ns2oS1WXDvc robb wolf's communication style is decidedly lower IQ, but does often acknowledge permeability and endotoxemia as neglected causal factors with easy solutions
16:07 < jrayhawk> for instance, i think he was the first public communicator pointing out https://scholar.google.com/scholar?q=cxcr3+atherosclerosis https://scholar.google.com/scholar?q=cxcr3+gliadin
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17:37 < fenn> Eli> These prices are extraordinary. How do they get them so cheap? Are they a charity that uses the data for data mining or something?
17:37 < fenn> lol
17:38 < fenn> people are always shocked when they find out how much the ingredients actually cost
18:39 < docl> pestering claude about how to make microparticles that can absorb a lot of heat fast in the cryogenic range has yielded some interesting ideas. apparently metal borohydrides have a huge enough endothermic potential that this could technically cool a human body from 0°C to -135°C while occupying 10% of the body's volume. this involves decomposing and releasing 4 hydrogen atoms though. sodium phosphide 
18:39 < docl> is almost as good (if you can manage phosphene in those microcapsules). actually getting the metal borohydride to decompose rapidly, I'm not so sure about (maybe by surface area maxxing + catalyst + electrical gradient?)
18:44 < docl> claude also suggests shape metal alloys, spin crossover complexes, and metal organic frameworks, but no good numbers there to rule them in or out with
19:10 < docl> er, that was aluminum phosphide I was looking at
19:52 < docl> ugh, and now it's telling me those salts dissolve exothermically. it must have gotten the sign backwards. guess that doesn't work
22:07 < hprmbridge> Eli> Ok, but is there some sort of monopoly in the blood testing market? If the unit cost is as low as the ownyourlabs site, does that testers have higher profit margins than Apple?
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--- Log closed Thu Jun 27 00:00:36 2024