--- Log opened Wed Jul 24 00:00:02 2024 00:21 -!- CryptoDavid [uid14990@id-14990.uxbridge.irccloud.com] has joined #hplusroadmap 01:02 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap 03:29 -!- CryptoDavid [uid14990@id-14990.uxbridge.irccloud.com] has quit [Quit: Connection closed for inactivity] 04:09 -!- srk [~sorki@user/srk] has joined #hplusroadmap 04:19 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Remote host closed the connection] 04:20 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap 04:32 -!- CryptoDavid [uid14990@id-14990.uxbridge.irccloud.com] has joined #hplusroadmap 04:54 -!- Croran [~Croran@user/Croran] has quit [Ping timeout: 252 seconds] 04:56 -!- Croran [~Croran@user/Croran] has joined #hplusroadmap 05:23 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 05:32 < kanzure> https://apolloinrealtime.org/11/ 05:39 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap 05:44 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Remote host closed the connection] 05:46 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 05:54 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 255 seconds] 06:26 < kanzure> where to download llama 3.1? 06:39 -!- CryptoDavid [uid14990@id-14990.uxbridge.irccloud.com] has quit [Quit: Connection closed for inactivity] 07:33 -!- flooded is now known as _flood 07:50 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Remote host closed the connection] 07:51 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 08:17 -!- etc-vi [~etc-vi@user/meow/girlchunks] has quit [Quit: nya] 08:18 -!- etc-vi [~etc-vi@user/meow/girlchunks] has joined #hplusroadmap 08:23 -!- etc-vi [~etc-vi@user/meow/girlchunks] has quit [Ping timeout: 252 seconds] 08:24 -!- etc-vi [~etc-vi@user/meow/girlchunks] has joined #hplusroadmap 08:47 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Remote host closed the connection] 08:47 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 09:10 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Ping timeout: 260 seconds] 09:32 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap 09:42 -!- delthas [~cc0@2a01:4f9:c010:cf0b::2] has quit [Remote host closed the connection] 09:42 -!- delthas [~cc0@2a01:4f9:c010:cf0b::2] has joined #hplusroadmap 10:06 < hprmbridge> kanzure> https://x.com/antonioregalado/status/1816120827894489218 11:34 < kanzure> "Progress and prospects for a nucleic acid screening test set" https://www.liebertpub.com/doi/10.1089/apb.2023.0033 (from Raytheon) 11:55 < kanzure> https://genesynthesisconsortium.org/ 12:15 -!- geneh2 [~cam@pool-173-66-187-118.washdc.fios.verizon.net] has joined #hplusroadmap 13:06 < docl> What's the min requirement for tattoo-like systems to breathe through your skin? 13:07 < docl> MOFs for O2 separation seem like they might do it if you can reverse the process biocompatibly 13:11 < docl> Can't do 100°C heating to release the oxygen. Ideally an ATP powered process. Blue light would be fine though. 13:23 -!- TMM [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.] 13:23 -!- TMM [hp@amanda.tmm.cx] has joined #hplusroadmap 14:23 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 16:49 -!- abetusk [~abetusk@syn-024-059-059-088.res.spectrum.com] has quit [Remote host closed the connection] 16:49 -!- abetusk [~abetusk@syn-024-059-059-088.res.spectrum.com] has joined #hplusroadmap 18:44 < hprmbridge> kanzure> tree genetic engineering startup https://tree-co.com/ 19:23 < hprmbridge> kanzure> https://www.statnews.com/2024/07/24/jiankui-he-crispr-babies-scientist-relocates-to-china-medical-tourism-hub/ 20:33 < fenn> "While each compound may have a different receptor binding profile, signaling appears to converge at the tyrosine kinase B (TrkB) and mammalian target of rapamycin (mTOR) pathways." https://en.wikipedia.org/wiki/Psychoplastogen 20:33 < fenn> not sure if this really needs to be a word 20:37 -!- mxz [~mxz@user/mxz] has quit [Ping timeout: 252 seconds] 20:37 -!- mxz [~mxz@user/mxz] has joined #hplusroadmap 20:39 -!- mxz_ [~mxz@user/mxz] has quit [Ping timeout: 264 seconds] 20:41 < fenn> you can download the official versions here but you have to register with HF and they are large files https://huggingface.co/collections/meta-llama/llama-31-669fc079a0c406a149a5738f 20:41 < fenn> meanwhile people are cooking up quantized variants and reuploading e.g. https://huggingface.co/mradermacher/Meta-Llama-3.1-70B-i1-GGUF https://huggingface.co/mradermacher/Meta-Llama-3.1-8B-Instruct-abliterated-i1-GGUF 20:41 < hprmbridge> setecastronomy1891> Are there any novel treatments/solutions for tinnitus? @hypercrowd et al 20:42 < fenn> still needs some time to test the quants and work out bugs, which always happens with a new base model 20:48 < fenn> would they publish it if they catch someone synthesizing DNA on the restricted list? how do we know the system is working or even necessary? 21:14 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap 21:47 < fenn> a higher fidelity llama-3.1 quant for vLLM https://huggingface.co/neuralmagic/Meta-Llama-3.1-405B-Instruct-FP8 21:48 < fenn> i expect someone to reupload the exact original model without a login gate eventually, it's just too soon 21:49 < fenn> FP8 is 99% as good as the original 22:00 < fenn> another big LLM was released today https://mistral.ai/news/mistral-large-2407/ 22:45 -!- mxz_ [~mxz@user/mxz] has joined #hplusroadmap 22:46 -!- flyback [~flyback@2601:540:c781:7f90:f93c:1479:626c:409a] has quit [Ping timeout: 276 seconds] 22:59 -!- flyback [~flyback@2601:540:c781:7f90::9622] has joined #hplusroadmap --- Log closed Thu Jul 25 00:00:03 2024