--- Log opened Wed Aug 28 00:00:35 2024
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05:18 < kanzure> i don't see a DM
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10:02 < NewtonTrendy> so should i order a 99% accurate Cas9 kit for the yamanaka transcription factors for my grandparents, and keep a fronzen copy of their dna to do it again if it fails, given that it would be cool at the age they are if they regenerated... and worth it
10:03 < NewtonTrendy> how do i target the stem cells?
10:03 < NewtonTrendy> the yamanaka factors do that?
10:04 < NewtonTrendy> i would assume people would enjoy my policy if that happened
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10:09 < hprmbridge> Eli> There’s science, pseudoscience, and science fiction. Using yamanaka factors on living humans seems sci fi to me. Different organs age at different rates. Different cells in these organs age at different rates. How do you deploy yamanaka to the correct places?
10:10 < hprmbridge> Eli> I don’t understand how they can solve this problem in vivo
10:15 < abetusk> kanzure, dm exists now
10:15 < hprmbridge> alonzoc> I think they are applicable in vivo but it won't just be a simple injection (or if it is that is *way* down the road). Unless we are talking about engineering fertilised eggs to have an easy "age reversal switch", any yamanaka aided age reversal in unmodified adults will likely be a set of therapies targetting aging in different sets of tissues.
10:16 < hprmbridge> alonzoc> Even if you could induce yamanka factors in all the cells of a living adult mammal the default outcome of that is still probably cancer
10:28 < NewtonTrendy> somewhere there is a patent for a molecule that does it
10:30 < NewtonTrendy> I will just leave this here again tho https://startalkmedia.com/show/is-aging-a-disease-epigenetics-with-david-sinclair/
10:30 < NewtonTrendy> it does work, but i dont know how
11:42 < hprmbridge> Eli> David Sinclair …
11:43 < hprmbridge> Eli> Let me know if it can ever be replicated by anyone else
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13:53 < hprmbridge> Eli> Easy way to increase healthspan seems to be to install an air purifier in your household. PM 2.5 is associated with dementia, cancer, and CVD: - Coal Pollution Impacts Explorer Deaths attributable to coal PM2.5: https://cpieatgt.github.io/cpie/
13:54 < hprmbridge> Eli> PM 2.5 from coal plants have decreased significantly https://cdn.discordapp.com/attachments/1064664282450628710/1278457755560185857/lucas-maps-GIF5.gif?ex=66d0e011&is=66cf8e91&hm=c440271b00f589df8b2f6154eb0c4be170d97e888fc55a3c5b538f2bccd05be8&
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18:42 < hprmbridge> heathal> https://www.tomshardware.com/pc-components/cpus/human-brain-organoid-bioprocessors-now-available-to-rent-for-dollar500-per-month
18:43 < hprmbridge> kanzure> yeah I've talked with them.. check the archives.
18:43 < hprmbridge> kanzure> but it hasn't done speech recognition yet... In fact, I don't even know what the most impressive demo they have done is.
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--- Log closed Thu Aug 29 00:00:36 2024