--- Log opened Fri Nov 22 00:00:57 2024
02:56 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap
03:23 -!- etc-vi [~etc-vi@user/meow/girlchunks] has quit [Quit: nya]
03:25 -!- etc-vi [~etc-vi@user/meow/girlchunks] has joined #hplusroadmap
04:26 -!- TMM [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.]
04:26 -!- TMM [hp@amanda.tmm.cx] has joined #hplusroadmap
08:11 -!- gl00ten [~gl00ten@bl5-237-194.dsl.telepac.pt] has joined #hplusroadmap
09:56 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 252 seconds]
10:59 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Remote host closed the connection]
11:00 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap
11:16 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Ping timeout: 252 seconds]
11:29 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap
12:44 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap
14:15 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds]
14:17 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has joined #hplusroadmap
14:38 < nsh> a condition came up in virtual pub (grandchild of a patron) - a rare variety of Angelman Syndrome, which usually follows from a genetic deficiency to express UBE3A (ubiquitin ligase) [1/250,000] but in this case it's the UBE1 (UBA1) which is ubiquitin-activating enzyme  
14:39 < nsh> looking into the situation wrt to gene therapy advances
14:39 < nsh> wondered if anyone has any comment
16:30 < jrayhawk> on the metabolic end, Dale Bredesen has done good work on preventing protein degradation to resolve cognitive disorders
17:30 -!- darsie [~darsie@84-112-12-36.cable.dynamic.surfer.at] has quit [Ping timeout: 264 seconds]
17:31 -!- gl00ten2 [~gl00ten@bl5-237-194.dsl.telepac.pt] has joined #hplusroadmap
17:33 -!- gl00ten [~gl00ten@bl5-237-194.dsl.telepac.pt] has quit [Ping timeout: 246 seconds]
17:37 -!- gl00ten3 [~gl00ten@bl5-237-194.dsl.telepac.pt] has joined #hplusroadmap
17:40 -!- gl00ten2 [~gl00ten@bl5-237-194.dsl.telepac.pt] has quit [Ping timeout: 255 seconds]
20:59 -!- mxz [~mxz@user/mxz] has quit [Ping timeout: 252 seconds]
20:59 -!- mxz [~mxz@user/mxz] has joined #hplusroadmap
21:00 -!- mxz_ [~mxz@user/mxz] has quit [Ping timeout: 260 seconds]
23:06 -!- mxz_ [~mxz@user/mxz] has joined #hplusroadmap
--- Log closed Sat Nov 23 00:00:58 2024