--- Log opened Mon Dec 16 00:00:20 2024
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01:45 < fenn> https://i.pinimg.com/736x/d7/7e/99/d77e99c737abe9205583b02cd4dff3e7--trolley-problem-problem-meme.jpg
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07:19 < hprmbridge> Eli> My version already answered: 1 engineer > 10,000 philosophers
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08:54 < hprmbridge> Eli> This sounds pretty concerning. Sort of a Pandora's box situation. If there was a mirror bacteria lab leak, how could it be stopped in the wild?
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10:13 < jrayhawk> there are already plenty of biological structures that are broken down by acid rather than enzymes
10:17 < jrayhawk> if stereochemistry were worth it, biology would be doing a lot more of it by now
10:36 < jrayhawk> for instance, the only strictly-essential stereochemical nutrient humans can't synthesize from non-stereochemical parts, cobalamin; already has naturally occuring stereochemistry
10:38 < jrayhawk> collagen, which is only sortof essential (in that humans tend to get chronic connective tissue disorders without it because we don't have prolase), also has naturally occuring stereochemistry
10:47 < jrayhawk> you don't get past the self-sensing that determines the delopment of hydrogen peroxide, cupric acid, lactic acid, etc. by creating something radically alien to existing molecules.
10:47 < jrayhawk> er, deployment
10:49 < hprmbridge> kanzure> https://www.businesswire.com/news/home/20241216400051/en/Gameto-Announces-World%E2%80%99s-First-Live-Birth-Using-Fertilo-Procedure-that-Matures-Eggs-Outside-the-Body
10:50 < hprmbridge> alonzoc> fenn: values don't really converge but can be aggregated into coalition choice functions. IIRC there are some proofs that it basically breaks down to a affine sum of normalised utilities weighted by shapley value. We have Harsanyi's aggregation theorem telling us any valid aggregation of utilities will ex post facto be implementable as a weighted affine sum of utilities (even though the actual
10:50 < hprmbridge> alonzoc> social choice function would be a barganning game or the like which is defo not a affine sum).
10:50 < hprmbridge> alonzoc> And all VNM-coherent utility functions (or atleast those which take the form of a time-discounted sum of state utilities) are lower bounded by some rescaling of the empowerment utility function which is basically the "low to no time preference" component of such a utility function
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10:57 < hprmbridge> kanzure> "Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation" https://academic.oup.com/humrep/article/38/12/2456/7303814?login=false#google_vignette
12:52 < hprmbridge> Eli> That’s a reasonable hypothesis. But it would be nice to know the teleological reason for your cells handedness. Is there a reason or is it simply an accident of nature?
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13:17 < jrayhawk> I don't know about L-vs-R, but, at the very least, because entropy overwhelmingly favors breakdown, it doesn't make sense to fight in opposite directions for better islands of metastability.
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18:13 < docl> https://www.youtube.com/watch?v=Z60Xla-0s_8 // Rotman Lens openEMS and Blender Simulation Guide
18:33 < fenn> "weighted by shapley value" sounds just as bad as "money is the unit of caring" - whoever's strategy dominates in the current economy gets to make all the decisions
18:36 < fenn> it doesn't make everyone happy
18:39 < fenn> argh now duckduckgo is making creative AI summaries and putting them in the usual place you'd see snippets of relevant page content
18:39 < fenn> over half of them begin "Learn how to use Shapley values,"
18:40 < hprmbridge> kanzure>  https://cdn.discordapp.com/attachments/1064664282450628710/1318407465884323890/Screenshot_20241216-203951.png?ex=67623622&is=6760e4a2&hm=92f76cc9d4457cb1d644a912d363e68bdc7f0bb4f99ee3572fa941b4bf5dec3f&
18:44 < fenn> i know where that is (virtual and real)
18:47 < hprmbridge> kanzure> tomorrow is the last imax showing i think
18:52 < fenn> AMC?
18:56 < fenn> nevermind, don't answer
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--- Log closed Tue Dec 17 00:00:21 2024