--- Log opened Fri Jan 31 00:00:04 2025
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04:23 < hprmbridge> kanzure> https://cloud.google.com/blog/topics/threat-intelligence/scatterbrain-unmasking-poisonplug-obfuscator
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05:41 < hprmbridge> kanzure> "Rapid lightsheet fluorescence imaging of whole Drosophila brains at nanoscale resolution by potassium acrylate-based expansion microscopy" https://www.nature.com/articles/s41467-024-55305-8
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07:50 < kanzure> hashcash as email anti-spam doesn't work because the CPU cost to signal non-spam is higher than non-spammers are willing to expend?
07:50 < kanzure> according to yevaud
07:52 < kanzure> which is a separate consideration from the unit economics of spammers, CPU time, PoW cost per spam email, and whatever spammer success or hit rate they need to meet in order to finance their scamming/spamming operations (probably a low probability, high volatility endeavor these days)
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07:53 < kanzure> power law distributions for whales or catching a big fish make arguments like "oh spammers can't afford to spend $0.25/spam message and therefore spamming will stop" less realistic
07:56 < kanzure> in a hashcash email world, if users were concerned about the instantaneity of sending email, then you could still deliver email before delivering a hashcash stamp, you can work on it in the background and send it later and it might still get there in time before the user checks their email (acquiring the recipient's attention has an escalating price, or something)
07:57 < kanzure> you could continue to "add work" to an already-sent email until it passes the recipient's attention grabbing threshold or the recipient otherwise opens the email
08:01 < kanzure> with a universally adopted digital currency you can attach money to an email and a friendly recipient that appreciated your message could send back the money, netting the total cost to zero (other than the cost of capital/money foregoing other economic opportunity while it sits in an inbox). no such universal digital currency exists.
08:14 < L29Ah> sms-activated accounts are the most universal digital currency today, for spam retardation purposes
08:14 < L29Ah> one can buy them wholesale for crypto as a result
08:34 < juri_> So, I've been recording my terminal sessions for .. probably about half... of my non-work non-IRC terminal interactions for a year. I'm disappointed to find that i could fit every development/administration interaction I had in my home from 2024 onto a CD. Three times. With room to spare.
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09:09 < kanzure> you are upset that your scripts generate succinct stdout?
09:10 < juri_> well, there was the one time i deployed kubespray. there went 100MB...
09:12 < kanzure> if only kubernetes was even *more* noisy
09:45 < andytoshi> juri_: with gzipping? or just plain text
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10:22 < hprmbridge> fodagut> fenn: it's sooo weird having met some of these ziz people in real life. I remember Gwen Danielson being this harmless guy that likes dragons (literal dragons).
10:22 < hprmbridge> fodagut> aparantly he faked his own death and is wanted in conjuction with multiple homicides? wtf?
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11:07 < kanzure> "Single-AAV CRISPR editing of skeletal muscle in non-human primates with NanoCas, an ultracompact nuclease" https://www.biorxiv.org/content/10.1101/2025.01.29.635576v1
11:08 < hprmbridge> alonzoc> wtf. I didn't know about Ziz.. Just as I think I am used to the lesswrong sphere.
11:10 < kanzure> "Randomizing the human genome by engineering recombination between repeat elements" https://www.science.org/doi/10.1126/science.ado3979
11:10 < kanzure> "an early step along the path to a minimal human genome"
11:33 < juri_> andytoshi: plain text.
11:33 < juri_> (with timing and direction information)
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12:28 < hprmbridge> fodagut> alethkit: (responding to message from last year) Atomic Machines is doing the Waldo path to nanotech
13:44 < alethkit> https://www.atomicmachines.com ? Thanks for letting me know!
13:46 < alethkit> shame their positions are all locked behind graduate engineering
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15:02 < fenn> @fodagut yeah gwen was my housemate for like 6 months, we have (had???) a similar personality and interests
15:03 < fenn> don't install demons in your head, kids
15:06 < fenn> i've vaguely heard about this "string of killings" thing which seems to just be two completely unrelated things, but if you know more i'd appreciate a link
15:07 < fenn> i wouldn't be surprised at all if they were planning to bomb some AI conference
15:09 < fenn> was hashcash supposed to be timelocked or is it easily paralleliable? because time and money are not actually equivalent and it changes the dynamics
15:11 < fenn> adding work to an already sent email is something a real spammer wouldn't do. the goal isn't to block phishing right. iirc the CPU time cost needed to disincentivize spam was less than a cent
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15:30 < L29Ah> https://github.com/openlifescience-ai/Open-Medical-Reasoning-Tasks
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16:10 < hprmbridge> Eli> Doctors don’t understand what’s coming. Medical AI will probably start in developing countries where there is a shortage of doctors. Then it will expand to developed countries due to extreme pressure on costs. differential diagnosis is just a state diagram.
16:10 < hprmbridge> Eli>
16:10 < hprmbridge> Eli> AI can talk to a patient for hours and never sleeps. And it will probably have a better bedside manner. And it can be constantly trained on latest standard of care.
18:05 < fenn> L29Ah: what is NewMes-v15? is huggingface censoring medical models?
18:06 < fenn> the quants are up but not the original so there's no readme
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23:32 < hprmbridge> fodagut> alethkit: try your shot and send your resume in. they're stealth mode and would probably want to know people who find them organically
23:38 < hprmbridge> fodagut> fenn: I don't know what the best writeup is
23:38 < hprmbridge> fodagut> https://openvallejo.org/2025/01/31/zizian-namesake-who-faked-death-in-2022-is-wanted-in-two-states/
23:38 < hprmbridge> fodagut> https://openvallejo.org/2025/01/27/man-killed-in-vallejo-was-main-witness-in-upcoming-murder-trial/
23:38 < hprmbridge> fodagut> https://openvallejo.org/2025/01/27/suspects-in-killings-of-vallejo-witness-vermont-border-patrol-agent-connected-by-marriage-license-extreme-ideology/
23:38 < hprmbridge> fodagut> https://vtdigger.org/2025/01/30/judge-orders-woman-facing-charges-related-to-fatal-border-patrol-shooting-held-in-custody/
23:39 < hprmbridge> fodagut> this seems to be pretty good: https://www.sfchronicle.com/projects/2025/ziz-killings-map-timeline/
23:41 < hprmbridge> fodagut> Don't install demons in your head indeed
23:43 < fenn> thanks, i didn't know about the Zajko case
23:45 < hprmbridge> fodagut> I'm *pretty sure* Gwen is the unknown person being held in connection with the border agent in Vermont
23:45 < hprmbridge> fodagut> *border agent murder
23:47 < hprmbridge> fodagut> @Eli you seem to think that AI will solve medicine, and not hallucinate treatments that end up killing you
23:48 < fenn> same could be said about doctors. the error rates matter
23:48 < fenn> or rather, error rate * risk of treatment
--- Log closed Sat Feb 01 00:00:05 2025