--- Log opened Sun Feb 16 00:00:19 2025
03:30 < fenn> facebook's AI model was able to decode up to 80% of input sentences from MEG recordings of participants' brainwaves as they typed
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04:06 < fenn> this is your decadal reminder https://medium.com/insurge-intelligence/the-pentagon-is-building-a-self-aware-killer-robot-army-fueled-by-social-media-bd1b55944298
06:10 < fenn> here's an example of a deep research report on a standardized ashwagandha extract from perplexity https://www.perplexity.ai/search/i-want-to-learn-the-pros-and-c-hKZL_GZNRJ.WEIS_WArg0Q
08:59 < hprmbridge> Eli> I'm wondering if these "deep research" reports are mostly good for an info dump. Like, it's hard for me to imagine that they are at the point where they could write a decent literature review. It's hard to imagine that LLMs can "connect the dots" by scanning multiple papers and coming to novel, non-halucinated, conclusions. Having said that, they are probably going to be amazing for basic grant
08:59 < hprmbridge> Eli> writing. And, I'm guessing most papers are probably using AI to outline the paper in the beginning. It definitely speeds everything up.
10:10 < juri__> fenn: I'd like to see that tried with one of us keyboard enthusiasts, with a custom mapped strangely shaped keyboard.
11:42 < hprmbridge> nmz787> Just bought some of that ksm66 a week ago
11:42 < hprmbridge> nmz787> My mom found some tea we had included it, and said it helped her sleep multiple nights in a row
11:43 < hprmbridge> nmz787> That deep research however says to take it in morning to avoid sleep disruption
12:55 < hprmbridge> Eli> like it says in the deep research report, it can affect the thyroid. Not a bad idea to keep an eye on that.
13:10 < nsh> .m https://x.com/ShangguanJiewen/status/1890913988352884934
13:10 < AugustaAva> ​twitter: <ShangguanJiewen> China has cured diabetes with stem cells. ␤  ␤ Ground breaking research on a human shows that with small, 30 minutes surgery, a patient was able to normalize their glucose levels. ␤  ␤ It's been more than a year and the outcome is holding. #China #Diabetes https://pbs.twimg.com/media/Gj1CUpvaYAAfYxG.jpg
14:19 < superkuh> Wow. Awesome.
14:31 < jrayhawk> T1D is two diseases. They did not cure the autoimmune disease.
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16:16 < hprmbridge> Eli> If this is a real result, I'm curious as to how IPSCs didn't get attacked by the immune system?
17:34 < jrayhawk> if it's years of post-honeymoon phase, the immune system may have deconditioned and moved on to other things.
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18:35 < fenn> .t https://pubmed.ncbi.nlm.nih.gov/39326417/
18:35 < saxo> Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient - PubMed
18:45 < fenn> maybe the iPSC derived islets look different to the immune system
18:47 < fenn> must be a big shot to have had two liver transplants
18:47 < fenn> and a pancreas transplant
18:51 < fenn> big shot's daughter
18:59 < fenn> they used basiliximab etanercept briefly after the iPSC-islet transplant, and since the patient had a transplanted liver she continued using tacrolimus mycophenolate mofetil and methylprednisone
18:59 < fenn> so loads of immune suppression
19:14 < fenn> "The trial is ongoing and includes three patients in total."
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21:01 < hprmbridge> nmz787> Fenn my mom's husband has had a liver and kidney transplant, and got them through the veterans association ( he retired from the army)
21:44 < hprmbridge> Eli> Well then …
21:45 < hprmbridge> Eli> Not a super optimal life.
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23:42 < fenn> why can't they design an anti-anti-islet cell antibody and have the immune system kill the part of the immune system responsible for autoimmunity
23:42 < fenn> and/or CAR-T cells to do the same
23:42 < fenn> it's not ideal but i don't know where the off switch is located
--- Log closed Mon Feb 17 00:00:20 2025