--- Log opened Tue Apr 01 00:00:03 2025
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03:10 < hprmbridge> kanzure> https://github.com/secp256k1lab/secp256k1lab
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11:46 < hprmbridge> Eli> Are these a concern for humans?
12:34 < jrayhawk> Yes. Constipation is typically peristalsis-inhibition from methane as produced by archaea.
13:38 < hprmbridge> Eli> ok interesting. I've heard of archaea in humans occasionally. Definitely seems like a rough environment for them. But, I'm not an archaea expert.
15:03  * L29Ah ponders the nature of his constipation and rare steatorrhea
15:25 < TMA> L29Ah: both can be an indication of liver/pancreas problem
15:26 < TMA> hard to tell without more data
15:32 < L29Ah> TMA: i tried augmenting it with pancreatic enzymes but apparently there's no effect
15:33 < L29Ah> so far settled on taking 5g magnesium hexahydrate daily to soften up stool, but i'm a bit concerned about possible underabsorption of fat-solubles
15:39 < L29Ah> ATT IgA + total IgA seem to rule out celiac disease
15:39 < jrayhawk> Emulsification via bile salts from the gal bladder is the primary thing mechanically stabilizing fat and enabling its absorbtion. People who I've chatted with who've had their gal bladders removed swear by https://www.amazon.com/NOW-Super-Enzymes-180-Capsules/dp/B0013OXKHC (capsules, not tablets)
15:39 < L29Ah> mayhaps my intestinal lining is messed up by a couple of infections 10y-ish ago, but the syndrome seems getting worse over time
15:41 < L29Ah> jrayhawk: interesting, thanks
15:41 < jrayhawk> gas testing (hydrogen, methane) would probably be useful.
15:42 < jrayhawk> https://www.gdx.net/products/sibo
15:42 < TMA> L29Ah: have you tried  fructus cardui mariae? (silimarin) it is reportedly beneficial for liver, but the research is poorly conducted
15:42 < L29Ah> TMA: no
15:43 < TMA> adjusting the diet and sometimes even successfully managing stress level helped me the most
15:43 < L29Ah> jrayhawk: seems unobtainum in the village i'm in
15:44 < jrayhawk> oh
15:44 < L29Ah> TMA: i've messed with diet a lot, added lots of fiber etc; didn't try long-term psychoactive drugs apart from caffeine tho
15:44 < L29Ah> i don't think i have a lot of stress as i live a (too-)laid-back life these days
15:46 < jrayhawk> FODMAP elimination would be the diagnostically helpful thing for SIBO/SIFO/SIAO. GAPS intervention diet, carnivore diet, elemental diet, etc. There's also plenty of pre-emulsified fats to work with, usually under the label "cream" or "butter".
15:53 < jrayhawk> re: too-laid-back: https://chrismasterjohnphd.substack.com/p/the-biomechanics-of-immune-dysfunction is also food for thought
15:58 < jrayhawk> it's also natural to have big claudin/occludin-opening lymphatic intestinal flushing events in response to toxic/immunological insults, heavy exercise, or high stress that might manifest as steatorrhea
16:00 < L29Ah> mind that i do HIDIT cycling ~2-3 times a week and 4-8h mountain hiking a few times a month; the too-laid-back part is more about my expenses being over my income despite living a frugal lifestyle, spending too little time on money-earning stuff
16:00 < jrayhawk> ah
16:01 < jrayhawk> well, "the trots" is the term for heavy-exercise-induced intestinal flushing.
16:01 < L29Ah> high-quality physical therapist sounds unobtainum
16:01 < jrayhawk> https://en.wikipedia.org/wiki/Runner's_diarrhea
16:01 < L29Ah> the exercise regime doesn't seem correlated with the syndrome
16:02 < L29Ah> (i was feeling lazy for several months at times and don't recall any changes)
16:03 < L29Ah> also feeling lazy about strength training for the last half a year, sticking to aerobic loads, no changes
16:05 < jrayhawk> For me, at least, the flushing events collapse my blood pressure so bad that it's unsafe for me to remain standing, but I have screwy nitric oxide metabolism.
16:07 < L29Ah> i keep a diary of shitting originally to assist me with my constipation-induced anus problems since 2019, someday i need to analyze it somehow
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22:19 < fenn> bitcoiner in spaaaaace. chun wang, creator of f2pool has taken his 1000th flight on spacex's dragon capsule, for no particular reason, to a polar orbit. he unfortunately will be experiencing rather poor space weather due to the x-class flare and CME which will be hitting earth tomorrow
22:19 < fenn> 999 aircraft flights, 1 spacecraft flight
22:27 < fenn> L29Ah: magnesium can form insoluble fatty acid precipitate like soap scum, especially with long chain and saturated fats. it also relaxes the bile ducts and can help expel bile plugs and smaller gall stones so still probably a good idea, especially with a "liver flush" protocol
22:28 < fenn> there are many causes of gallstones. if you have bile insufficiency it could be due to duct blockage induced by bile stagnation from fasting or a chronic low fat diet
22:29 < fenn> bile duct scarring can also initiate blockages
22:31 < fenn> doctors seem completely ignorant of the entire subject and seem over eager to remove the gallbladder, which of course you can't grow another one
22:31 < fenn> there *are* mainstream medical options to soften gall stones but for bad reasons they don't go with this route as the first line of treatment
22:40 < fenn> a gall flush is something like: 1 tablespoon granulated epsom salt (magnesium sulfate) dissolved in 1 cup apple juice or cold water and 1g vitamin C. eat a non-fat breakfast and fast the rest of the day. in the evening drink it over the course of a couple hours. you should have a funny spreading feeling in your tummy. now chug a mix of 1/2 cup lemon juice or grapefruit juice and 1/2 cup olive
22:40 < fenn> oil. you will have super liquidy diarrhea due to the magnesium, and this will go on for a couple hours
22:41 < fenn> the magnesium relaxes and expands the bile ducts, the oil stimulates the gall bladder to contract and expel bile (and hopefully gall stones and semi-solid blockages)
22:41 < jrayhawk> is that for cholesterol stones or bilirubin stones?
22:42 < fenn> cholesterol iirc
22:42 < fenn> i'm not sure there's a difference since it's a physical mechanism
22:44 < fenn> the creator has some theory about parasites ("flukes") initiating the stone with their dead bodies
22:52 < fenn> uh i don't see the coronal mass ejection on the space weather prediction so perhaps it was yesterday
22:52 < fenn> yes
22:52 < fenn> well nevermind then
--- Log closed Wed Apr 02 00:00:04 2025