--- Log opened Mon Jun 02 00:00:00 2025
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10:39 < RangerMauve> fenn I'd be nice if gene editing was available to all instead of the ultra wealthy
10:39 < hprmbridge> kanzure> it's already available. you can buy the parts.
10:41 < RangerMauve> Is syhtnesizing arbitrary DNS something a home lab can do yet?
10:41 < RangerMauve> *DNA
10:44 < hprmbridge> kanzure> you can do that by hand or you can buy a machine to do it.
10:44 < hprmbridge> nmz787> Yeah but it's annoying and chemistry laden
10:45 < RangerMauve> How much are the machines? IMO the dream is to streamline generating bacteria that can produce medical compounds. Making the DNA to populate your stock culture, and sharing the bacteria + extraction tools so communities can bypass big pharma manufacturing processes
10:46 < RangerMauve> It'd be nice if every household had the equivalent of a computer but for bioengineering
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10:51 < fleeky> are there current gene editing techniques that are actually beneficial for longevity ? 
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10:56 < hprmbridge> nmz787> The machines can be cheap, chemicals less so, waste processing  not insignificant. Several folks in here have been thinking on the subject for 15 years... Still easiest way to get DNA is to pay someone else to make it
10:59 < hprmbridge> kanzure> fleeky: see https://diyhpl.us/wiki/genetic-modifications/#longevity
11:04 < RangerMauve> Who runs diyhpl.us BTW? Want to mirror it to peer to peer protocols via distributed.press? Could be useful for resilience. I have an instance I can contribute with a cron for syncing periodically if wanted. Could also set up DNS to resolve "hyper://diyhpl.us/" to the p2p URL in compatible browsers
11:04 < hprmbridge> nmz787> Probably the CIA
11:05 < RangerMauve> More reason to back it up before the DOGE budget cuts hit it :P
11:15 < hprmbridge> kanzure> it's a wiki. just clone diyhpl.us
11:15 < hprmbridge> kanzure> er, git wiki
11:16 < hprmbridge> kanzure> https://github.com/kanzure/diyhpluswiki is a mirror of the git repo if you for some reason don't want to follow the instructions on diyhpl.us for git clone
11:16 < fleeky> oh wee 
11:16 < fleeky> just git cloneee
11:17 < L29Ah> 20:01:21]<hprmbridge> kanzure> fleeky: see https://diyhpl.us/wiki/genetic-modifications/#longevity
11:17 < L29Ah> borken link, no such anchor
11:18 < fleeky> kanzure: none of these have actually been tested on humans yet eh ? 
11:18 < fleeky> still a pretty nice list!
11:18 < fleeky> ooo , eye color virus please
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11:21 < hprmbridge> kanzure> there's a longevity section somewhere in there
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14:18 < kanzure> https://jitsi.github.io/handbook/docs/architecture "... Jitsi Broadcasting Infrastructure (jibri) - set of tools for recording and/or streaming a Jitsi Meet conference that works by launching a Chrome instance rendered in a virtual framebuffer and capturing and encoding the output with ffmpeg." what? why do they have to use a browser?
14:27 < L29Ah> because jitsi meet people are mad
14:28 < L29Ah> there is https://github.com/avstack/gst-meet already also
14:34 < kanzure> L29Ah: anything else i should know about jitsi? was thinking about hacking a demo on top of jitsi infrastructure.
14:35 < kanzure> i want to persist the webrtc connection and camera/mic holds between meetings and just switch out the backend server data (ok possibly the client will have to refresh some UI elements). i'm trying to avoid a full client-side app reset or avoid a full client reload.
14:37 < L29Ah> apparently it is very hard today for a js developer not to use a browser to do things
14:37 < L29Ah> kanzure: don't confuse jitsi and jitsi meet
14:38 < L29Ah> kanzure: i doubt jitsi meet can do the entirety of interactions over webrtc and won't break at the second the server goes down, as today it has a lot more stuff than just video conferencing
14:39 < kanzure> yeah i don't know the jitsi protocol, maybe it's webrtc+XHR ? webrtc+websocket? i dunno
14:39 < L29Ah> and mind that lots of people live with CGNAT so for webrtc to work they must use a proxy
14:40 < L29Ah> me neither
14:48 < hprmbridge> harpoonshot> Damn glowers
15:11 < jrayhawk> i suspect xiu is appropriate bridging every modern A/V transmission protocol, but i have not used it yet
15:11 < jrayhawk> https://github.com/harlanc/xiu
15:12 < L29Ah> i wonder what makes people think their repo stars history plot belongs in README
15:16 < jrayhawk> in this case i suspect it's because almost all general-purpose AV transmission bridges are the effort of one person or company, which loses interest in public maintenance after a couple years, and the more specialized bridges do not attract much interest.
15:17 < jrayhawk> "we are not a deadend project"
15:21 < hprmbridge> kanzure> amazon chime sdk looks ok
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15:23 < fleeky> https://link.springer.com/article/10.1186/s12859-025-06158-5
15:24 < fleeky> gut feeling is this could be used with different types of information networks .. like maybe a way to link up various ai knowledge bases in general?
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17:01 < fenn> .t
17:01 < saxo> Universal multilayer network embedding reveals a causal link between GABA neurotransmitter and cancer | BMC Bioinformatics
17:04 < fenn> MultiXVERSE
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--- Log closed Tue Jun 03 00:00:01 2025