--- Log opened Thu Jul 24 00:00:50 2025
00:02 < fenn> no i'm looking at the wrong year, duh
00:02 < fenn> the white house is requesting $4B for NSF
00:06 < hprmbridge> kanzure> here have some navelgazing https://boriquagato.substack.com/p/the-second-world
00:07 < hprmbridge> kanzure> (and high trust applies to trusting your innovators btw)
00:21 < fenn> does he realize the second world was the soviet union
00:26 < hprmbridge> .monokhrome> Congress is full of middle aged and elderly people - why are they so eager to slash cancer research? Logically you'd expect them to pouring huge amounts of money into it
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00:30 < fenn> God has a plan
00:31 < fenn> i'm not entirely sure of the mechanics of how this works. i think the president appoints a director to each agency and then that director submits a budget to congress for approval, and it would be very bad for the appointee to submit a different budget and there's not a lot of ways for congress to fix a bad budget request, and also they don't really care
00:31 < fenn> i mean it would be bad for the director's career
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01:17 < jrayhawk> it's not a bad thesis for the-second-world-as-everyone-else-understands-it, though
02:25 < hprmbridge> .monokhrome> After the fall of communism a lot of ex communist bloc countries ended up economically in between africa and the west in terms of development, so there's some overlap there between the usage
02:28 < fenn> i just mean literally this is where the words come from
02:28 < fenn> .wik third world
02:28 < saxo> "The term Third World arose during the Cold War to define countries that remained non-aligned with either NATO or the Warsaw Pact." - https://en.wikipedia.org/wiki/Third_world
02:30 < fenn> it's a good article but the terminology sucks as far as being clear in communication and winning over people
02:32 < fenn> allegedly the low trust bad people causing the fall of formerly orderly soviet society were the businessmen and government officials, so it's not a great metaphor
02:32 < fenn> defectors
02:33 < fenn> why is language so hard
02:34 < hprmbridge> .monokhrome> People. All language problems are really just people problems.
06:02 < L29Ah> 06:06:08]<jrayhawk> deflation makes investment in useful human endeavours less attractive
06:02 < L29Ah> not really, it doesn't matter as long as the rate is predictable
06:05 < TMA> investment is good if the return is good with respect to the risk and alternatives
06:07 < TMA> inflation just makes more ideas more profitable. if the alternative is losing say 5 % of the value losing just 2 % of the value is good in comparison
06:07 < TMA> it is still a net loss though
06:08 < TMA> I would argue that inflation makes investment in _useless_ endeavours attractive
06:08 < L29Ah> it doesn't make ideas profitable, it makes you buy bitcoin while you could just hodl instead if it wasn't inflating, if you had bad (yet still growing your inflating number) ideas
06:10 < L29Ah> s/bitcoin/mainstream inflation-negating asset like gold, real estate, bonds and s&p500/
06:12 < hprmbridge> kanzure> according to https://effectuation.org/hubfs/Journal%20Articles/2017/05/Alvarez_et_al-2007-Strategic_Entrepreneurship_Journal-1.pdf not all entrepreneurship is a matter of risk management style decisioning of risk or return, but instead heuristics around acceptable loss
06:14 < L29Ah> those are the ways to shortcut the same calculation; are you arguing for tricking people with irrational behavioral economics en masse?
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06:16 < hprmbridge> kanzure> is rational economic decision possible in the presence of uncertainty (not just known quantified risk)?
06:17 < L29Ah> ah, i misread you; now i understand you meant expected value vs variance optimization
06:19 < hprmbridge> kanzure> "defies any rules and systemization" is just another way of saying you are giving up on the problem https://mises.org/mises-daily/risk-uncertainty-and-economic-organization
06:19 < L29Ah> but i think yes, one can very well optimize for expected value while keeping variance low enough to avoid harsh economic hardships
06:20 < hprmbridge> kanzure> also in the presence of actual uncertainty it's hard to distinguish a computable decisioning versus " individuals become owners and entrepreneurs because they overestimate their own ability to anticipate future prices — and the supply of entrepreneurs is sufficiently large that at least a few guess correctly"
06:22 < hprmbridge> kanzure> which isn't to say that local knowledge or edge isn't possible ever
08:37 < hprmbridge> Eli> Is IRB about ethics or legal liability? Doctors are highly risk averse. In tech, if you do illegal hacking, it can be a great thing to put on your resume. In medicine, a group of people in your profession determines you can no longer treat people. Science by consensus. Doesn't seem to apply to weaponizing viruses in a country that shoots whistleblowers for some reason.
08:38 < hprmbridge> kanzure> there is also a federal funding aspect of IRBs
09:40 < flyback> https://www.foxnews.com/sports/pro-wrestling-icon-hulk-hogan-dead
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14:42 < hprmbridge> .monokhrome> Alas poor hulk. I'm actually impressed by the number of guys who abused steroids in the 70s and 80s and are still alive, ie schwarzenegger, stallone, jesse ventura
14:53  * L29Ah considers abusing steroids after getting older
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15:39 < kanzure> L29Ah: one must first take steroids before one can begin to abuse steroids
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16:14 < kanzure> hello Classical 
16:15 < fenn> how do you do that
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16:16 < kanzure> like anyone else does, by suffering immense pain for a moment of human greeting
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16:25 < fenn> .t https://bioboot.github.io/bimm143_W20/class-material/nw/
16:25 < saxo> Interactive demo for Needleman–Wunsch algorithm
16:25 < fenn> just a little fun
16:27 < fenn> i was thinking about using vision LLMs to OCR handwriting and they work better on small chunks of text, so you'd have to align and merge overlapping chunks
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17:26 < hprmbridge> kanzure> for some reason "spermatozoa-somatic cell fusion" is trending on X.
17:31 < hprmbridge> kanzure> even if it doesn't occur naturally, i think it should be possible to experimentally induce spermatozoa-somatic cell fusion via the standard cell-cell fusion techniques or even deliberate microinjection.
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18:25 < hprmbridge> kanzure> "epistemically homeless"
19:46 < L29Ah> https://bitcoinhivemind.com is it any good?
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20:12 < hprmbridge> kanzure> discreet log contracts work on bitcoin already, I forget what sztorc is doing here
20:13 < hprmbridge> kanzure> also he has gone off the rails several times and seems to have some sort of hatred of bitcoin devs?
20:23 < L29Ah> https://dlc.wiki/ no mentions of prediction markets
20:25 < hprmbridge> kanzure> IIRC someone has a way to make DLC positions transferable or assumable.
21:36 < fenn> $1k leg exoskeleton https://www.kickstarter.com/projects/dnsys/dnsys-z1-knee-exoskeleton-defy-gravity-go-beyond
21:36 < fenn> well.. joint assist
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--- Log closed Fri Jul 25 00:00:51 2025