--- Log opened Thu Sep 04 00:00:30 2025
01:16 < fenn> kanzure> "Natural systems possess rich nonlinear dynamics that can be harnessed for unconventional computing. Here, we report the discovery that a common potato (Solanum tuberosum) can serve as an effective physical reservoir computer, leveraging its electrochemical properties for complex data processing tasks. ... including spoken digit classification and gesture recognition.
01:17 < fenn> kanzure: do you recall the source of this quote? i can't find it in your physical-intelligence folder, nor my own papers. was this a hoax? looking at the logs i seem to have read the paper (and been unimpressed)
01:17 < fenn> i only have the potato memristor paper
01:25 < fenn> maybe i got confused and thought the memristor paper was the source of the quote
01:27 < fenn> or maybe it's top-secret mad science that's been memoryholed because THEY don't want you to know this one simple trick...
01:37 < fenn> you've been busy on the wiki
01:52 <+gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=9f1ead73 fenn: desty nova tiphares brain chip reveal >> http://diyhpl.us/diyhpluswiki/users/fenn/BAA09_16_brain_bio-chip.png
01:58 < hprmbridge> kanzure> it's not real
01:59 < hprmbridge> kanzure> although maybe it could work?
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02:00 <+gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=82357ab8 fennwiki: inline the brain biochip image >> http://diyhpl.us/diyhpluswiki/distillation/
02:01 < fenn> yeah i wasn't sure because it seems plausible
02:02 < fenn> like if the starch granules acted like percolating nano-whatsits
02:02 < fenn> combined with the learning/training effect of the "memristor"
02:04 < hprmbridge> kanzure> it's similar to the electroactive hydrogel paper, where the gel is made to play pong
02:05 < hprmbridge> kanzure> and the neuron culture one that does spoken digit classification
02:05 < fenn> yeah but those are neurons, come on
02:05 < hprmbridge> kanzure> what if it's just the ECM or agar?
02:06 < hprmbridge> kanzure> what was the null hypothesis here
02:06 < fenn> i don't know man, everythings complex and i don't feel special anymore
02:07 < fenn> i wouldn't expect the hydrogel to work because it's just a smooth continuous material
02:08 < hprmbridge> kanzure> it has varying concentrations of ions in local swelling zones
02:08 < fenn> after you zap it
02:08 < fenn> how does it develop the initial pattern?
02:09 < hprmbridge> kanzure> https://diyhpl.us/~bryan/papers2/ai/physical-intelligence/Electro-active%20polymer%20hydrogels%20exhibit%20emergent%20memory%20when%20embodied%20in%20a%20simulated%20game%20environment%20-%202024.pdf
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02:36 < hprmbridge> kanzure> "Harnessing ionic complexity: A modeling approach for hierarchical ionic circuit design" https://arxiv.org/abs/2410.04310
02:43 < fenn> the article would benefit from a single photo of the contraption
02:44 < fenn> "The trapezoidal diode is formed from thin aqueous polyelectrolytes molded between two thin plates of glass."
05:30 < hprmbridge> kanzure> "No known systems can do simultaneous cross-strand base editing (XBEOM)."
05:31 < hprmbridge> kanzure> huh, where did that typo come from. it should have been XBE.
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07:49 < hprmbridge> kanzure> are the ancephalic clones really necessary? why not comatose regular clones?
07:57 < L29Ah> for ethical reasons
07:57 < L29Ah> less people are pissed about brainless humans than comatose humans
07:57 < hprmbridge> kanzure> making them ancephalic won't convince the bioethics people
07:57 < L29Ah> bioethics people aren't uniform
07:57 < hprmbridge> kanzure> their whole job is to invent reasons why what you are doing is unethical
07:57 < hprmbridge> kanzure> their job isn't to come up with reasons why what you're doing is actually okay.
07:58 < L29Ah> and a minority that won't get pissed enough to suicide bomb your labs doesn't matter
09:04 < L29Ah> https://tinystash.undef.im/il/3T8DMM4M5DpFpnEZSWf6yzSYpRCznqtd2aQZrdzUxTNugTJgYVNbzmnQdc9ZM83WEA2iU6jqAYHQJD2kExmfBxysNLVefmvMht4qtQdAesiRje.jpg
09:19 < RangerMauve> Tag yourself
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10:29 < kanzure> "On the epistemology of black hole astrophysics" https://library.oapen.org/bitstream/handle/20.500.12657/63938/1/978-3-031-26618-8.pdf#page=227 (page 227)
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12:01 < kanzure> "Evolution of cortical neurons supporting human cognition" https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(22)00208-X (2022) with a particular focus on dendritic tree size and pyramidal neurons.
12:09 < kanzure> "... The highest most protracted overproduction of human synapses (up to third decade of life) was described for associative layer IIIC pyramidal neurons in the human dorsolateral prefrontal cortex." https://link.springer.com/chapter/10.1007/978-3-031-36159-3_4
12:17 < kanzure> "Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming" https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(24)00327-8 (2024)
12:17 < kanzure> ".. Transient Yamanaka factor (YF) expression during development expands neocortex; YF-treated mice show enhanced cognitive skills; Intermittent YF expression is tolerated by adult principal hippocampal neurons."
12:17 < kanzure> "Embryonic induction of YFs perturbed cell identity of both progenitors and neurons, but transient and low-level expression is tolerated by these cells. Under these conditions, YF induction led to progenitor expansion, an increased number of upper cortical neurons and glia, and enhanced motor and social behavior in adult mice. Additionally, controlled YF induction is tolerated by principal ...
12:18 < kanzure> ...neurons in the adult dorsal hippocampus"
12:20 < L29Ah> https://www.lifespan.io/news/some-bioethicists-promote-lifespan-limitation/ lifespan.io is getting busy with strawman fighting :/
12:26 <+gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=12c7279d Bryan Bishop: add various references >> http://diyhpl.us/diyhpluswiki/sleep/
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15:21 < hprmbridge> kanzure> https://youtu.be/MgQbPdiuUTw
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--- Log closed Fri Sep 05 00:00:31 2025