--- Log opened Sat Oct 25 00:00:18 2025
00:38 < fenn> guys the future arrived (again) 2 weeks ago
00:38 < fenn> .t https://www.youtube.com/watch?v=Eu5mYMavctM
00:39 < fenn> figure 03 humanoid looking pretty and high class modernist
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00:53 < hprmbridge> kanzure> see backlog.
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03:23 < fenn> more precise protein diffusion models enable engineered ion channels: https://www.nature.com/articles/s41586-025-09646-z (david baker lab/RFdiffusion)
03:23 < fenn> .t
03:23 < saxo> Bottom-up design of Ca2+ channels from defined selectivity filter geometry | Nature
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05:34 < L29Ah> http://institutrobotov.ru/en.html for your entertainment
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11:48 < hprmbridge> nmz787> Re https://english.cast.org.cn/xkx/fzlm/syzsxx/art/2025/art_1151760547.html  and DBMS, are they talking database Management systems? It seems like something that's already libre and open source
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12:00 < hprmbridge> kanzure> i have not been able to purchase a figure, optimus or other humanoid robot. unitree G1 seems purchasable but also seems like i would be buying myself a second job...
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14:30 < hprmbridge> kanzure> "Singapore's Bioethics Advisory Committee (BAC) advises against heritable gene editing" https://isomer-user-content.by.gov.sg/154/f27c283e-3f3a-46e4-af3d-cbfb2b92f2bb/BAC_2025%20Oct_Human%20Nuclear%20Genome%20Editing%20Advisory%20Publication.pdf
14:31 < stipa> some time ago somewhere i read about gene editing
14:32 < stipa> the patient died
14:32 < hprmbridge> kanzure> wow, is that the first time a patient has ever died?
14:32 < stipa> but that was a last resort
14:32 < hprmbridge> kanzure> or did we previously lose someone to a medical procedure at least once?
14:33 < stipa> well
14:33 < stipa> i would argue that the biggest problem for most cases is micro poisoning 
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17:28 < hprmbridge> kanzure> Ring-1T https://arxiv.org/abs/2510.18855
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18:16 < hprmbridge> kanzure> Ling-T1 https://ant-ling.medium.com/deep-insight-efficient-inference-introducing-the-trillion-parameter-ling-1t-model-77d6170e5e8e
18:16 < fenn> there are also 3B, 15B, 16B-A1.6B MoE, 104B in addition to the 1T model
18:16 < fenn> is Ling and Ring the same thing?
18:16 < fenn> i've never heard of this lab somehow
18:16 < hprmbridge> kanzure> reasoning
18:17 < hprmbridge> kanzure> ring is the reasoning version
18:17 < fenn> right. awkward
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--- Log closed Sun Oct 26 00:00:19 2025