2008-09-06.log

--- Day changed Sat Sep 06 2008
pkso what's new in transhumanism today?00:08
pkI saw Dean Kamen featured on the news with his "Luke hand", good to see that getting more press00:09
geneit's not a neural interface00:10
fennit's not?00:10
geneit's not anything like direct neural interfacing00:10
geneit has balloons that provide feedback00:10
fenni thought they used the nerve stubs left in the chest (previously controlled the arm but now dead)00:10
genenope00:11
geneit is also some control software00:12
pkit's controlled by muscles further up the arm00:12
pkiirc00:12
pkthere is an arm that's controllable via neural interface though00:14
geneguess they got some sort of neuron interfacing going with it now00:14
fennapparently the luke arm is flexible enough to use several different input sources00:15
fennone of them is the nerve-stub-in-the-chest method; search for kuiken http://www.spectrum.ieee.org/print/5957 00:15
pkI'm interested in Dean Kamen's ability to hyperfocus on one specific problem00:16
pkand use the best in current technologies to address it00:16
genecool00:16
genethere really needs to be a better way to interface with neurons00:16
fenni read a popular article yesterday about implanting chips into moth pupae, the moth brain then grows around the chip00:18
fennso.. how bout them SQUIDs00:19
pkyeah I saw that before00:19
geneMoths != human00:20
fenngene: i bet a human brain would grow around and interface with a chip implanted when it was an embryo00:21
geneyeah, but then you might end up with developmental problems00:22
fennwell shit, i've got eyeglasses and bad wisdom teeth, dont you consider that a developmental problem?00:22
pkheh00:22
pkwell that would be an interesting experiment to try on mice00:22
fennwow SQUID can do NMR in a microtesla field00:26
genecan squid see individual neurons?00:27
fennsince it has extremely high temporal resolution, you could discriminate between separate firing events , but i cant think of a way to map that onto a particular neuron, because it has low spatial resolution (?)00:29
genedang00:30
fennmaybe some way to do phased array sensing at high frequencies (small wavelength)00:30
fennbut i dont even know the words to describe what i'm thinking00:30
fennanyway, the ability to do nmr in normal earth magnetic field gets you fMRI at least00:31
geneyou can do fMRI 00:32
geneusing Earth's magnetic field?00:32
fennwith a sensitive enough detector00:32
fennhmm one nice thing about vinge-style laser contacts is that you could read with your eyes closed00:34
genelaser contacts00:35
gene?00:35
fennas seen in _Rainbows_End_00:36
fenngoes in your eye, connected to wearable computers, displays a virtual reality overlay00:36
fennsquid is only one half of input/output00:37
genehaven't read that one yet00:38
fennalthough... (and why hasnt anyone else said anyting about it?) you could use phased array microwaves as a highly selective rTMS-ish input device00:38
fennusing the same superconducting coils as the microwave antennae00:39
fennor however squid works.. /me reads more00:39
genemaybe one could make an mri contrasting agent00:40
genethat responds to sodium gradients00:40
fenner... water?00:41
fennhydrogen is really useful for nmr/mri because it is so light00:42
genesodium is useful to look for because when neurons signal they do something with it00:43
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fenngraah00:50
fennwhy do i bother00:51
* fenn dumps some text anyway00:51
fennThe concentration of sodium in normal soft human tissues is 20-80 micromol/g wet weight, or about 1/1600th of the water hydrogen concentration which forms the basis of conventional magnetic resonance imaging (MRI). In addition, sodium's MRI sensitivity is only about 9 percent of hydrogen's. Despite these enormous handicaps, sodium imaging at clinical MRI field strengths of 1.5 Tesla with ~0.2 ml resolution is practical in ~15 min scan times or less.00:51
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ybiti know why i'm getting fat!02:52
ybithttp://www.sciencedaily.com/releases/2008/09/080904102804.htm02:52
ybitit's only natural in geniuses02:55
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ybitso what is the optimum overweight size and what is the correlation between krispy kreme donuts intake and intelligence?02:57
ybitno debating if i should eat the last box of dozen donuts at the student organizations, it's for my brain02:58
ybitor so i will rationalize :P02:58
fennwtf is 'excessive calorie intake' anyway03:07
fenncalories have nothing to do with obesity03:08
fennits not like your brain is a diesel engine03:09
Phreedomfenn: but drain does consume quite a lot of energy04:04
Phreedomof course only if you actually use it04:04
Phreedom*brain04:14
Phreedom:)04:14
fennthe scientists are making the assumption that only the energy expended while doing the 'hard thinking task' counts04:21
fennbut really you would be thinking about it subconsciously at other times as well04:22
fennand you have to replenish neurotransmitters and remove waste products etc04:22
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-!- Topic for #hplusroadmap: Semi-intro http://www.youtube.com/watch?v=ZXKbzbeipmI http://diybio.org/ http://openwetware.org/ | diy bio tools: http://biohack.sf.net/ | Automated societal knowledge (put it to work): http://heybryan.org/exp.html | Channel wiki: http://heybryan.org/mediawiki/ | F/OSS re: Kurzweil: http://heybryan.org/fernhout/13:07
-!- Topic set by kanzur1 [] [Mon Aug 11 14:37:25 2008]13:07
[Users #hplusroadmap]13:07
[ bkero ] [ faceface] [ kanzure_ ] [ Nade ] [ Phreedom ] [ ybit] 13:07
[ chizu ] [ fenn ] [ kanzure_1] [ Nofaris] [ procto ] 13:07
[ elias`] [ freer ] [ kanzure__] [ nsh ] [ willPow3r] 13:07
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-!- Channel #hplusroadmap created Sat Mar 22 15:44:12 200813:07
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* kanzur1 is back15:59
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Blobfishhey16:23
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geneyou there kanzure?16:23
kanzureYes16:23
kanzureHey Blobfish.16:24
kanzureHey gene.16:24
kanzureI just got back. Sorry about all that.16:24
BlobfishHey, nice to meet you!16:24
genehey16:24
BlobfishGene has told me quite a bit about you16:24
geneabout the biohacking toolkit and stuff16:24
kanzureAh, good. You like?16:24
* nsh would like to take this opportunity16:24
Blobfishhaha, of course16:24
Blobfishit's pretty awesome stuff16:25
kanzurensh: Hm?16:25
geneBlobfish is also working on a repstrap16:25
nshto advise all present, with great emphasis, to search pubmed for the author John Mattick16:25
Blobfishyeah, cutting some aluminum right now16:25
nshand read at least every abstract on the first page of results16:25
nshbefore you get all learn'd up with wrongness16:25
genehuh?16:26
geneKanzure16:26
kanzureYes?16:26
geneI talked to that guy about the polymerase yesterday16:26
kanzurensh: http://www.ncbi.nlm.nih.gov/sites/entrez?term=John%20Mattick&search=Find%20Articles&db=pmc&cmd=search16:26
kanzuregene: Oh?16:27
kanzureBlobfish: Do you know about closure engineering?16:27
nshthis at a minimum: http://jeb.biologists.org/cgi/content/full/210/9/152616:27
genehe doesn't think it's possible to do that sort of thing 16:27
genefor now16:27
nshkanzure: http://www.ncbi.nlm.nih.gov/sites/entrez?term=John%20Mattick&search=Find%20Articles&db=Pubmed&cmd=search16:28
genemainly because we really have  much of an idea of how proteins fold16:28
nsh(pmc is unfortunately still rather exclusive)16:28
Blobfishfascinating16:28
geneand not much in the way of computational power to simulate them16:28
kanzuregene: We don't need to know how proteins fold. We just evolve the mutated polymerases to our liking.16:28
genehow?16:29
nshkanzure, you mean brute force?16:29
kanzurensh: No, hold on.16:29
kanzurehttp://heybryan.org/diagrams/retarded_polymerase.png16:29
genehow do you measure the fitness of a polymerase like that?16:29
nshalthough16:30
geneit's easy to measure the fittness of things like antibodies16:30
* nsh ponders16:30
nshkanzure, 404 on that png16:30
kanzurewtf16:30
kanzureIs the server working at all?16:30
nshwait, no server16:31
geneyou just stick something covered in antigens in and see what sticks16:31
geneso what is the deal about mattick16:31
kanzuregene: You measure it by the length of the resultant strands and their relative brightness given some sort of fluorescent tag for certain nucleotides.16:31
kanzurensh: I did apache2 -k restart and I'm getting nothing. Any ideas?16:32
Blobfishkazure: do you host your own server?16:32
nshkanzure, server IP?16:32
kanzureBlobfish: Yes.16:34
nshtraceroute loses you the server at apogeenet.net16:34
Blobfishrofl.  are you hosting it from your dormroom?16:34
geneBlobfish you should see his setup16:35
kanzurensh: Ah, yes, the IP has, in fact changed.16:35
kanzureBlobfish: Hell yeah.16:35
Blobfishhaha, way to violate the terms of service! /me applauds16:35
kanzureBlobfish: My setup is even more of a violation of TOS.16:35
Blobfishkanzure: are you using dyndns for your domain name?16:36
nshnew IP is whutpls?16:36
kanzureNah. I should use something like it.16:36
kanzurensh: fixing16:36
kanzurehttp://66.112.232.136/16:36
nshty16:36
kanzureOkay, heybryan.org and austinbrains.org should be working now.16:37
Blobfishkanzure: heybryan.org works16:37
genebtw16:38
geneKanzure, there's a programing contest today16:38
Blobfishwho here runs linux?16:40
Blobfishor bsd?16:40
kanzuregene: Where?16:41
kanzureBlobfish: Linux for most of us.16:41
geneDang I forgot where16:41
geneat about five16:41
geneI think 16:41
nshARGH VISTA: HATE16:41
nshwon't let me save changes to hosts file16:42
nshfucking retarded OS16:42
Blobfishlinux here too16:42
geneit is16:42
geneAnd I am running it16:42
* nsh only wishes16:42
geneI need to switch to linux16:42
Blobfishi dual boot...but I haven't been in Vista for about 4 months16:43
genecool16:43
* nsh awaiting external to upgrade his laptop to "computer" status16:43
BlobfishI'm on a tablet PC, every time i upgrade the kernel I have to recompile the kernel modules for the active digitizer16:44
geneSo how much computational power do we all have here?16:44
nshapparantly, we have supercomputers16:44
Blobfishhmmm...2.1 ghz with turion 64 x2 on laptop...dunno about the integrated GPU16:44
Blobfishthen my desktop has probably about the same...except with an 8600 gpu with half a gig of memory16:45
genedo we have enough computational power to simulate proteins16:45
genelots of proteins16:45
kanzurehttp://heybryan.org/mediawiki/index.php/Computational_chemistry16:45
kanzurehttp://heybryan.org/mediawiki/index.php/Computational_biology16:45
kanzureSee for yourself.16:45
Blobfishwe might have enough to simulate lots of spaghetti...16:46
nshyay16:46
nshstupid fucking vista16:46
nshthat16:46
nsh's 5 minutes of my life i'll never get back16:46
Blobfishlol16:46
Blobfishnsh: what's stopping you from using linux?16:46
nshhdd full16:47
geneno kidding on the spaghetti16:47
genethat's basically what proteins are16:47
nshluggage handlers killed my external 16:47
Blobfishnsh: TSA luggage handlers?16:47
nshno, ryanair16:47
* nsh doesn't do failmerica :-)16:48
geneluggage handlers also killed  the RepRap child16:48
geneperhaps they have a thing against high technology?16:48
nshi suspect that might be the case16:48
nshor competancy16:48
nshwhich is the tastier -y version of competance16:49
Blobfishanyone here from the NSA logging our conversation?16:49
nshthis guy on reddit told me the government runs freenode. he seemed pretty legit ;-)16:50
Blobfishlol16:50
nshthe nsa is of course logging everything plaintext16:50
Blobfishwhich country do you plan on moving to when this one becomes "too corrupt"?16:51
* nsh smiles16:51
geneSpace16:51
geneThe Moon16:51
geneEuropa might be nice too16:52
Blobfishpangea...anyone?16:52
nshkanzure, my brain is dead from science overload, can you summarise this retarded polymerase idea in one or two pithy sentences pls16:52
nshi don't think we're allowed to make landings on europa16:52
nshi have a distinct memory of an exhortation to that effect16:52
kanzurensh: Laser-control of polymerase.16:52
nshcontrolling what?16:52
kanzureWrites.16:53
nshstart/stop?16:53
kanzureAnd what to write.16:53
nshoh16:53
genewhy laser control?16:53
nshyaypipedreams :-)16:53
genewhy not LEDs16:53
kanzureI have no special attachment to lasers.16:53
kanzureLEDs would be great if they work.16:53
genecool16:54
geneI think our best option for DNA synthesis might be that maskless lithography method using a DMD chip16:54
Blobfishwhat about control by a laser on a shark's head?16:54
geneheh16:55
kanzuregene: The idea was that the polymerase would be self-replicable.16:55
genelasers aren't particulary self replicable16:55
kanzureBuild a fire.16:55
BlobfishPeople are.16:55
kanzureAlso, organic LEDs exist.16:55
geneguess they do16:55
Blobfishdoes anyone else consider life an STD?16:56
genebut the maskless lithography method might be faster an easier to accomplish16:56
kanzuregene: It doesn't accomplish the goals though.16:56
kanzureThe point is the self-replicable and DNA synthetic aspects of it. DNA synthesizers, the type that we can go get in a lab, can otherwise be built. If that's your goal, go do that.16:57
genewe still need to bootstrap the process16:57
kanzurePurchasing metals isn't going to lead to bootstrappedness :-p.16:58
* kanzure gets started on his synthetic biology circuit creator thingy.16:58
kanzureHm. The machine is locking up.16:59
geneanyway I have been thinking about building a lego universal constructor16:59
kanzureHow is it going to make its own legos?16:59
geneit doesn't 16:59
geneit assembles legos17:00
kanzureSigh.17:00
genethis is phase A-B of the nasa self-replicating moon base study17:00
Blobfishdang, i need more clamps17:00
kanzureNot really.17:00
kanzureThis isn't the sort of thing you do ad-hoc.17:00
kanzureIn the study, Freitas clearly outlined closure engineering17:01
kanzurewhich is, I dare say, not ad-hoc :)17:01
genephase A is build something that can build itself from it's own parts17:01
genephase B is have it build other things from parts17:01
kanzureI don't think you understand, if you're not building the legos then you can't say it's constructing the legos.17:02
genephase C is have it build it's parts from raw materials17:02
genephase D is have it mine the raw materials17:02
genebtw17:02
kanzureThat's a load of shit.17:02
kanzureIt's the same exact strategy that RepRap is using17:02
kanzureAnd they don't do replication.17:02
BlobfishReprap can print shit now?17:03
genereprap can't assemble itself yet17:03
geneit's not even on the scale17:03
kanzureYeah, but they like to lie about it. :-)17:03
kanzureLike to the NY Times and so on.17:03
kanzureAnyway, here's the thing: you're not going to be able to show that you have achieved self-replication from side-projects that aren't integrated with one another.17:04
genethat's media overstatement17:04
kanzureYou've mentioned sandbots, claypit bots, lego bots, and all sorts of other constructors and assemblers, but none of them do the job.17:04
kanzureNo, that's them overstating i.17:04
kanzure*it.17:04
genefirst off if you making a machine capable of assembling anything from parts17:05
kanzure?17:05
geneit can assemble the machines necessary to make the parts17:05
genea machine made from nuts and bolts that can assemble itself17:06
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genethe machines made from nuts and bolts that can make nuts and bolts17:06
kanzureHave you been listening to fenn at all?17:06
* kanzure is wondering if we've made any progress at all here17:06
kanzureAlso it's possible that I'm overcritical at the moment here.17:07
geneyeah17:07
genethe lego machine would demonstrate the assembly process17:07
geneI am thinking of making a gantry crane made from legos that can assemble another working copy of itself from lego parts17:08
kanzureBut how do you show that you could integrate the fabricational complexity necessary to manufacture legos in the future?17:09
genethis is a demonstrator17:09
genebut kanzure17:10
geneI have made a 3d printer out of legos17:10
geneon the gantry crane thing17:10
geneadditional lego parts that don't exist in nature may have to be fabricated17:10
kanzureI feel like I'm talking to a wall. Look: I am not disagreeing with you. Yes, you have indeed made a 3d printer out of legos and you indeed can make a 3D assembler out of legos, but you haven't shown me the evidence that randomly making up these designs necessiates the path towards a replicator. 17:11
kanzurensh or fenn, how the hell did I explain it to either of you ?17:11
kanzureybit?17:11
genewell the other option is to use something besides legos17:12
* Blobfish wishes he had a few more arms17:12
* nsh too brainspazed to work out what is wanted of his memory17:13
nshask me on monday or something17:13
nshno wait, wednesday17:13
nshstill conference on monday17:13
genelike actually making a replicating gantry from steel or machined parts17:13
kanzureThe materials don't matter.17:15
kanzureThe design matters. You don't have evidence that randomly assembling parts together will result in "closure". That's what I'm talking about, and that's why skdb exists.17:16
geneif you can assemble anything you will get closure17:18
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genea robot arm assmbles a milling machine that can machine the robot arm's parts17:18
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genethen you work on feeding the mill with metal ingots17:21
geneit's all there in the Advanced Automation for Space Missions study17:23
genebtw17:24
kanzure?17:24
genecan you do machining with electron beams17:24
kanzureNot sure.17:24
geneI have another idea about replication17:25
genedo you know what electron beam melting is?17:25
geneif you don't look it up17:26
genethe basic idea is that an electron beam is used to fuse metal powder together17:26
geneyou use an electron beam melting machine to make it's casing and most of it's parts17:27
geneand parts for the electron beam assembler17:28
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ybitoi kanzure20:05
ybitoh20:05
ybitn/m20:05
ybitbut hey to you anyway :)20:05
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ybityou didn't explain that to me friend20:17
BlobfishHow did this room get its name?20:17
ybit+ there's much more to say20:18
ybitkanzure named it20:19
ybitnot sure which came first, the wiki or irc channel20:19
Blobfishkanzure:  how did you come up with the name?20:19
ybityou do know what h+ is right?20:20
Blobfishnot exactly20:21
ybith+ = transhumanism20:21
Blobfishah, thanks20:21
ybitnp20:21
Blobfishnow it makes sense20:21
ybithttp://heybryan.org/mediawiki/index.php/Roadmap20:21
Blobfishafter 7 holes, I'll be finished with the y axis of my McWire RepStrap20:22
ybit"[19:18] <ybit> + there's much more to say" should be 'not much more'20:29
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Nadehmmn21:17
Nadeanyone read stephen wolframs book, a "new" kind of science?21:17
ybitno, but i have read the wikipedia article on it atleast twice :)21:25
Nadehttp://www.wolframscience.com/nksonline/toc.html21:40
Nadeyou can read it all for free there21:40
Nadebut i'd suggest you skip to the interesting parts, he does go on a bit21:41
Nadei just find it fascinating21:41
Nadeit's all so elegant21:41
Nadethe language of mathematics is an absurd lens in which to view the world, thinking in terms of computation makes much more sense21:42
Nadeanyway, lets just hope them at cern haven't got their equations wrong ;)21:42
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kanzureNade, many of us hear have heard of NKS and have "agents" within the NKS realm.21:49
kanzureHowever, I haven't actually read the book.21:49
kanzureBlobfish: The name came about because of that 'roadmap' which makes little sense in retrospect.21:49
kanzureAlso, because people keep on coming in here. That's a good reason to keep the channel methinks.21:49
kanzureThere was a mailing list from 2007, but I haven't found a suitable relayhost since I got to the dorm in July.21:49
Nadewell you can read it for free online21:51
Nadealthough i warn you, it's pretty big21:51
kanzureIt's safe to say that I know what it's about without having actually read Stephen's book.21:54
kanzureAnd I somehow surround myself with people who have read it, or at least rant about it, so I think I'm in the clear [for the time being].21:55
kanzure Sunday, September 7th between 7am and 10am. <--- my server will be down21:57
Nadewell you should at least look at the pictures 21:58
Nade:p21:58
kanzureOh, I have.22:00
kanzureI know what he's proposing too -- in general, a computational basis of reality, taken from the CA approach, if you read into it deeply enough.22:00
Nadeyep22:11
Nadealthough I have to say I find the stuff about nature and diversity far more interesting..22:11
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kanzurehttp://en.wikipedia.org/wiki/MODOK 22:18
kanzure"MODOK underwent an artificial mutagenic process and bioengineering, granting him a superhuman mental acumen, making him, in theory, capable of knowledge and comprehension beyond the human ability to understand. "22:18
kanzure" .. He has developed machinery that allows him to turn himself into data and e-mail himself to anywhere on Earth."22:18
kanzureEww. MIME types.22:18
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kanzurehttp://heybryan.org/~bbishop/docs/type_links.html Each section of links is separated by a link with 'pgroup' in the URL. What I'm doing is just waiting until I come to a link with the pgroup attr/var and then I set the current category type to that, until I hit something else like it, but maybe there's a cleaner way to do this. Bah.23:33
* kanzure wonders how telling all of this is http://www.last.fm/user/kanzure23:46

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