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genehacker | photosensors are cool | 00:17 |
---|---|---|
genehacker | you think you make a fast response photosensor that causes hydrogen ions to be pumped out of the cell? | 00:20 |
fenn | pumping out would take energy | 00:49 |
fenn | if all you want to do is open a channel, look at the LiGluR... paper | 00:49 |
genehacker | you can do stuff with hydrogen ions | 00:50 |
fenn | copypaste link http://heybryan.org/books/papers/Millisecond-timescale, genetically targeted optical control of neural activity - Boyden.pdf | 00:51 |
genehacker | I want to make a photosensor useful for manufacturing stuff | 00:51 |
genehacker | that can be grown | 00:51 |
fenn | there was another paper i was reading but dunno where that went | 00:51 |
fenn | here's that paper http://linkinghub.elsevier.com/retrieve/pii/S0896627307003443 | 00:54 |
fenn | Remote Control of Neuronal Activity with a Light-Gated Glutamate Receptor | 00:54 |
fenn | anyway | 00:54 |
fenn | you can use the same mechanism for proton channels too | 00:54 |
fenn | look at the diagram with the clamshell snail eyeball thingies | 00:55 |
fenn | figure 1 | 00:59 |
genehacker | oh that works | 00:59 |
genehacker | close enough | 00:59 |
genehacker | SNAIL EYES? | 00:59 |
genehacker | sounds interesting | 01:00 |
fenn | oh it looks like they just tethered the glutamate molecule to the receptor with an azobenzene | 01:01 |
fenn | silly me | 01:01 |
fenn | when light strikes azobenzene it changes shape, stuffing the glutamate in the clamshell binding site | 01:02 |
fenn | which opens the ion channel | 01:02 |
genehacker | woohoo | 01:14 |
genehacker | I got a reed switch | 01:14 |
genehacker | and it's definately a reed switch | 01:17 |
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wrldpc | Old: "Scientists in the US have shown that "electrocorticographic" signals from the brain can be used to manipulate an external device." o.O | 02:01 |
fenn | quite old | 02:07 |
fenn | i assume you've been reading about braingate? that was 2003 i think | 02:08 |
wrldpc | yeah .. way old. | 02:18 |
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kanzure | there's a Cajal Blue Brain initiative? | 07:12 |
kanzure | ybit: maybe you should look into that? | 07:17 |
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kanzure | Quantum Entanglement in Photosynthetic Light Harvesting Complexes | 08:11 |
kanzure | http://arxiv.org/abs/0905.3787 | 08:11 |
kanzure | ok, so I have some old software on my server that I wrote maybe as a joke or just because I was bored | 08:21 |
kanzure | the autoscholarzen stuff that flips up PDFs on the screen | 08:21 |
kanzure | it doesn't quite work because it endlessly generates zombie processes (oops) | 08:21 |
kanzure | and the navigation between one PDF to another is really lame (does not exist- not sure how to implement it without hacking ghostview or xpdf or something) | 08:21 |
kanzure | but I figure it might be worth using it now that I have a reasonable collection of sufficiently interesting papers | 08:22 |
kanzure | you know, as opposed to watching television all the time or something | 08:22 |
kanzure | I guess one way to implement keyboard navigation would be to make the xpdf processes conserve a history of which pages were viewed previously even if it's on to another file | 08:24 |
kanzure | so that next/previous buttons work | 08:24 |
kanzure | and then space for pause/unpause of the flipping stream | 08:24 |
kanzure | and an accelerator knob :) or something | 08:25 |
kanzure | "it's SCIENCE!" | 08:25 |
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genehacker | you might try using a blue glowing usb knob of doom or a maybe an accelerator pedal | 09:29 |
genehacker | to drive through papers | 09:30 |
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kanzure | adl.serveftp.org will be down until we refinish rewiring the mess of the electrical cord system in the lab | 09:58 |
kanzure | zotero 1.0.10 update is out apparently | 09:58 |
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genehacker | in the ADL I see? | 11:36 |
kanzure | yeah | 11:36 |
kanzure | we have some new boxes | 11:36 |
kanzure | and some nice keyboards | 11:37 |
kanzure | rerouted a lot of the power supplies and ethernet cables | 11:37 |
genehacker | do they have names yet? | 11:37 |
kanzure | minsky is the new box | 11:37 |
kanzure | davinci is the server | 11:37 |
kanzure | newell is one of the boxes I was doing windows pythonOCC development on | 11:38 |
kanzure | chomsky is also floating around here somewhere | 11:38 |
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kanzure | http://woodysprops.com/page1.html | 12:19 |
kanzure | I'm thinking of adding one of these to my apartment. | 12:19 |
kanzure | something like this? http://woodysprops.com/005.jpg | 12:19 |
Utopiah | nerd antique, how fashionable | 12:21 |
genehacker_ | hahaha | 12:21 |
kanzure | I want to do this: | 12:21 |
kanzure | http://woodysprops.com/037.jpg | 12:21 |
kanzure | *that's* what I want in my apartment | 12:21 |
genehacker_ | what would you use it for | 12:21 |
kanzure | world domination | 12:22 |
kanzure | other nefarious activities | 12:22 |
kanzure | etc. | 12:22 |
Utopiah | classic | 12:22 |
genehacker_ | of course | 12:22 |
Utopiah | in the volcanic island | 12:23 |
genehacker_ | you know that modern day war rooms(they call em fusion centers cuz they fuz a whole bunch of data together) just use big screens and touch screens I think | 12:23 |
genehacker_ | hey you know what? | 12:23 |
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kanzure | no | 12:23 |
kanzure | I don't know what | 12:23 |
genehacker_ | if we drill a sufficiently deep hole we might be able to make our own volcano | 12:24 |
genehacker_ | one way to drill a really deep hole is to use a very power laser | 12:24 |
genehacker_ | like an oxygen iodine laser | 12:25 |
kanzure | another way is bacteria | 12:25 |
genehacker_ | bacteria don't work at the temperature of magma now do they? | 12:25 |
kanzure | well, they should. | 12:25 |
genehacker_ | in b4 cool the whole damn hole | 12:25 |
kanzure | force 'em to by growing a ridiculously heat resistant strain | 12:25 |
genehacker_ | that's crazy | 12:26 |
genehacker_ | no that's batshit crazy | 12:26 |
kanzure | out of the crazy things you bring up in here, | 12:26 |
genehacker_ | we'd have to make silicon based life for that | 12:26 |
kanzure | growing a heat-resistant strain is not anything of concern. | 12:26 |
genehacker_ | Temperatures of most magmas are in the range 700°C to 1300°C | 12:27 |
genehacker_ | find me something that isn't killed by that | 12:27 |
kanzure | I said grow/evolve one. | 12:28 |
kanzure | also, show me a technique for proving life doesn't already exist in magma or something | 12:28 |
kanzure | I have not yet read any studies about people attempting to find life in magmas | 12:28 |
genehacker_ | highest temperature that anything lives at is 122 degrees C | 12:29 |
kanzure | and before that, the highest was 121 celsius | 12:29 |
genehacker_ | yeah :( | 12:29 |
genehacker_ | I don't think proteins can exist at 700 degrees Celsius | 12:30 |
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kanzure | this should be an easy experiment | 12:31 |
kanzure | first start with some colonies that grow optimally at 37 degrees (typical incubator) | 12:31 |
kanzure | then ramp it up and keep on selecting for the colonies that grow the best at the different temperatures | 12:31 |
kanzure | the trick would be making an incubation chamber that has fine-tuned temperature controls I guess | 12:32 |
genehacker_ | anyway if something lives at really high temperatures, why don't we find stuff in autoclaves or steel foundaries? | 12:32 |
kanzure | do people look in steel foundaries? | 12:32 |
genehacker_ | they look in airplane fuel tanks | 12:32 |
kanzure | is there any particular resource that life could live off of in steel foundaries other than the metals? | 12:32 |
kanzure | it's not like they're dumping nutrients into the smelting pots all the time :p | 12:33 |
genehacker_ | found mysterious corrosion, turned out there's bacteria that corrodes fuel tanks to live or something like tha | 12:33 |
kanzure | heh, I doubt they corrode pistons though :) | 12:33 |
genehacker_ | they can reduce metals though | 12:33 |
kanzure | kind of hard to live in that environment | 12:33 |
genehacker_ | pistons? | 12:33 |
genehacker_ | oh in car engine | 12:33 |
kanzure | yeah, the exploding types | 12:33 |
genehacker_ | shame that nothing can live there | 12:34 |
genehacker_ | you know what I wonder? | 12:34 |
genehacker_ | I wonder why there aren't any lifeforms with diamond in them or metal plates | 12:34 |
genehacker_ | is metal hard to obtain in the environment? | 12:35 |
genehacker_ | there are certainly copper binding proteins, I'd like to make something that makes metal plates | 12:36 |
genehacker_ | so I can make "protein walls" for my bacterially induced geofront | 12:36 |
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--- Log closed Thu May 28 13:52:43 2009 | ||
--- Log opened Thu May 28 13:52:54 2009 | ||
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kanzure- | hm, wonder why that happened | 14:06 |
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drazak_ | kanzure-: bacteria can live in diesel, and probably jet fuel, I bet it could find a use for Fe or to carbon fixate from steel | 14:47 |
kanzure- | I didn't say otherwise :) | 14:51 |
* drazak_ just sayin | 14:53 | |
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xp_prg | genehacker your very smart | 15:11 |
genehacker | huh? | 15:11 |
genehacker | what now? | 15:11 |
genehacker | my diybio post? | 15:12 |
kanzure- | these new boxes look spiffy | 15:29 |
genehacker | can they fly? | 15:30 |
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kanzure- | they can hum. | 15:37 |
kanzure- | does that count? | 15:37 |
genehacker | no that doesn't count | 15:37 |
drazak_ | genehacker: what's your name | 15:37 |
genehacker | Gene Hacker | 15:38 |
genehacker | ok not really | 15:40 |
genehacker | my real name is John Smith | 15:40 |
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kanzure | I don't like how my IP address randomly changed today. | 16:24 |
fenn | kanzure: should i be over there? | 16:34 |
kanzure | eventually, yeah | 16:35 |
kanzure | I suggest taking a laptop so that you're not disabled for a few hours | 16:35 |
genehacker | don't like kanzure? | 16:37 |
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genehacker | that | 16:37 |
genehacker | is a great thing | 16:38 |
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* fenn gets on bicycle | 17:09 | |
fenn | tallyho! | 17:09 |
* xp_prg gets on the bycycle with fenn | 17:12 | |
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katsmeow-afk | Japanese researchers have genetically engineered monkeys whose hair roots, skin and blood glow green under a special light, and who have passed on their traits to their offspring, the first time this has been achieved in a primate. | 18:16 |
katsmeow-afk | They spliced a jellyfish gene into common marmosets | 18:16 |
katsmeow-afk | The protein glows under blue and ultraviolet light | 18:16 |
* katsmeow-afk wonders ho well the marmosets see in blue and uv light now that the insides of their own eyes (and their retinas) will glow when that lightis present | 18:17 | |
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kanzure | Hi ober. | 19:32 |
ober | hello | 19:44 |
ober | missed last nights meeting but saw the email | 19:44 |
fenn | where was "last nights meeting"? | 19:45 |
kanzure | Austin Hacker's Association. | 19:54 |
kanzure | which apparently is mostly for security professionals | 19:56 |
kanzure | hm, I thought it meant hackers in general | 19:56 |
kanzure | biohackers, lifehackers, peoplehackers, bytehackers, tree hackers, .. | 19:56 |
ober | Magias | 19:59 |
ober | Mangias even. | 19:59 |
genehacker | we're not biohackers | 20:02 |
kanzure | why nto? | 20:02 |
kanzure | *not? | 20:02 |
genehacker | we're "amateur biologists" | 20:02 |
genehacker | hacker scares people | 20:03 |
genehacker | we need to do some PR | 20:03 |
genehacker | so we don't get vanned | 20:03 |
kanzure | bullshit | 20:04 |
kanzure | just stop doing any PR | 20:04 |
genehacker | I'm joking | 20:04 |
genehacker | and parodying diybio | 20:05 |
genehacker | which is concerned with such | 20:05 |
genehacker | topics as PR | 20:05 |
genehacker | everyone wants to do PR but not real bio | 20:06 |
genehacker | but let's get to the point | 20:06 |
genehacker | you got any papers on making phosphoramidite nucleosides? | 20:06 |
ultraleibniz | yes, somewhere. let me think. | 20:07 |
genehacker | I also need some way to draw an internal gear in cad | 20:07 |
ultraleibniz | what is an internal? | 20:07 |
genehacker | hold up | 20:08 |
genehacker | http://www.bpt.on.ca/106059.gif | 20:08 |
genehacker | this | 20:08 |
genehacker | I need one of those so I can make this: | 20:10 |
genehacker | http://www.act.sys.okayama-u.ac.jp/kouseigaku/research/okamoto_wobble_06/english.htm | 20:10 |
genehacker | and 3d print a working motor | 20:11 |
genehacker | err make that stepper motor for a 3d printer I'm building | 20:11 |
kanzure | http://www.bhk-lab.com/publications/2003/69.pdf | 20:13 |
genehacker | you do know we get free 3d prints on the machine on the 3rd floor? | 20:15 |
kanzure | hm, in the acknowledgments of that paper they thank "the Lab for Modified Nucleic Acid Systems". | 20:18 |
kanzure | why do I keep seeing references to Tetrahedron Letters | 20:19 |
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fenn | you need to set up wondershaper on the server and route outgoing packets through it | 20:34 |
fenn | so it doesnt take thirty seconds to load a webpage | 20:35 |
kanzure | better? | 20:41 |
fenn | no. i guess i dont know what the problem is | 20:56 |
kanzure | try again. | 20:56 |
fenn | might be my computer somehow | 20:56 |
kanzure | I turned it off and reconfigured. | 20:56 |
kanzure | please excuse the delay in service. | 20:56 |
fenn | still takes about 30 seconds. i can get an IP from nslookup in about 1 sec so i dont think it's DNS issues | 20:59 |
kanzure | are you torrenting? | 21:00 |
kanzure | my lag is 2.02 on this lappy, 1.16 on the monolith, .. | 21:00 |
fenn | nope just email and web | 21:01 |
kanzure | is it possible that god hates me | 21:03 |
fenn | error does not compute | 21:03 |
genehacker | so how soon do you think we can start getting results from SKDB? | 22:01 |
genehacker | before 2010? | 22:01 |
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greenshoe | ultraleibniz: kanzure-: me -> aha | 22:53 |
greenshoe | hey. | 22:53 |
genehacker | ? | 22:56 |
greenshoe | hey - | 23:01 |
greenshoe | ultraleibniz mentioned this channel on list for Austin Hackers, so I thought I'd /join and see who was here. | 23:02 |
greenshoe | I'm starting to get plugged into the community here in Austin.. Probably not doing much security related stuff right now, as I need to find some work, and there's a hardware project I'd like to do first... | 23:04 |
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kanzure | genehacker: I think that would be reasonable (before 2010), yes. | 23:16 |
genehacker | ok good | 23:17 |
kanzure | right now it's just me pretending to know lisp, and that's the holdup more than anything else | 23:17 |
genehacker | here's the deal | 23:17 |
kanzure | once I translate it back into pseudocode, the symbolic equation extraction mechanism can be generically applied to the hardware representation format | 23:17 |
genehacker | do you know what hyperinflation is? | 23:18 |
kanzure | "In economics, hyperinflation is inflation that is "out of control", a condition in which prices increase rapidly as a currency loses its value. ..." | 23:18 |
genehacker | yeah | 23:18 |
genehacker | well absolute worst case we could experience it here the earliest around 2010 | 23:19 |
kanzure | out of who's control? | 23:20 |
genehacker | in other words I'd like to engineer some redundancy to insure that we have progress | 23:21 |
genehacker | *engineer redundancy into the system | 23:22 |
kanzure | which system? | 23:22 |
genehacker | everything | 23:23 |
genehacker | IE let's make miniature factories so if hyperinflation happens it won't affect us | 23:24 |
genehacker | or something like that | 23:24 |
greenshoe | building a forge is a good first step. | 23:48 |
greenshoe | If you can refine metal, you can make just about anything you'd normally have to buy. Plus, you can recycle metals. In prctice you get a lesser quality metal without haveing some new raw material to mix in... | 23:49 |
greenshoe | but still useful. | 23:49 |
greenshoe | or I'm missing some elaborate allegory. See yaz. | 23:56 |
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