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genehacker | I know the allegory | 00:47 |
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genehacker | http://www.grabup.com/uploads/240ccede5360b093dbf298f8946025a5.png | 00:52 |
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kanzure | heh. building-sized animatronics. | 08:55 |
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kanzure | there's an IRC for emacs? really? | 09:29 |
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kanzure | hello ybit | 10:07 |
ybit | hey kanzure | 10:09 |
kanzure | ligandosides? | 10:26 |
ybit | nucleoside mimics... | 10:27 |
ybit | linkinghub.elsevier.com/retrieve/pii/S1631074803001346 | 10:27 |
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kanzure | http://www.stanford.edu/group/kool/kool.htm | 11:54 |
kanzure | what you really need to do is block the polymerase template strand site with some sort of super molecule that responds to different wavelengths of light and changes shape to one of the four nucleotides | 12:08 |
kanzure | it may be easier to just start from scratch and find four chemicals that you would like to use as the artificial nucleotides or whatever | 12:09 |
kanzure | and then hack the polymerase via in vitro compartmentalization to make better choices for incorporation | 12:09 |
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xp_prg | http://www.physorg.com/news162649086.html | 12:28 |
xp_prg | so, it only took 7 embryos?! | 12:28 |
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fenn | what am i supposed to do with this inventory list? | 17:55 |
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fenn | this thingy was generated by a python script http://imagebin.org/50847 | 18:01 |
fenn | i dont know what it is, but it proves the concept for heekscad at least | 18:02 |
genehacker | instructables is down? | 18:05 |
fenn | the internet just blew up | 18:09 |
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bryan_ | blah | 18:10 |
fenn | good morning to you too | 18:11 |
bkero | Any of you d00dz want a cheap computer? Coworker at intel is selling his rig. XFX nForce 680i SLI board, E6600 Core 2 Duo, and 2x1GB DDR800 Mushkin for $200 | 18:13 |
fenn | tbh that doesnt sound terribly impressive | 18:14 |
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bryan_ | for some reason grub doesn't want to boot up ubuntu on my laptop | 18:16 |
bryan_ | all I did was boot into windows to install MSVC9 2008 .. | 18:16 |
fenn | you get the grub menu? | 18:17 |
bryan_ | fenn: did some spectrophotometry of 680 nm today of extracts from the spiral filter running on 1/12th hp | 18:17 |
bryan_ | no | 18:17 |
bryan_ | just a grub command line | 18:17 |
fenn | huh. | 18:17 |
bryan_ | anyway, the data shows an increasing trend in absorbance | 18:17 |
bryan_ | for n=1 to n=5 runs through the filter of the same sample | 18:17 |
fenn | is that a good thing? | 18:18 |
bryan_ | I don't know | 18:18 |
bryan_ | I think something might be wrong with the universe | 18:18 |
fenn | maybe it's breaking up clusters of cells | 18:18 |
bryan_ | honestly this thing shouldn't work | 18:18 |
bryan_ | and we didn't do measurements on the other stream output to see if it's greater or less on that one | 18:18 |
bryan_ | so that needs to be checked too | 18:18 |
bryan_ | I did have one idea though | 18:18 |
bryan_ | what if you take the output and route it into a new tank to do incubation | 18:19 |
bryan_ | then you're positively selecting for algae that is easily harvestable via this method | 18:19 |
bryan_ | so do that for some number of generations | 18:19 |
fenn | eh.. good luck with that | 18:19 |
bryan_ | no? | 18:19 |
fenn | well, try it and see | 18:20 |
bryan_ | is there something obvious that I am neglecting that you see? | 18:20 |
bryan_ | I don't know whether or not to trust myself after this thing works .. | 18:20 |
bryan_ | something is definitely wrong with the universe | 18:20 |
genehacker | whoa | 18:20 |
fenn | isnt it just a scaled up version of the microfluidics thing? | 18:20 |
bryan_ | although I guess we haven't compared absorbance between both samples | 18:20 |
genehacker | does it work? | 18:21 |
bryan_ | fenn: but it's supposed to only work for laminar flows | 18:21 |
bryan_ | this is not a laminar flow | 18:21 |
bryan_ | genehacker: not sure | 18:21 |
fenn | how do you know it's not laminar? | 18:21 |
genehacker | it works | 18:21 |
genehacker | HAHAHA | 18:21 |
genehacker | increased absorbance= increased concentration | 18:21 |
bryan_ | fenn: reynolds number is way too large | 18:22 |
bryan_ | genehacker: but we didn't test the other output stream | 18:23 |
nsh | http://nextbigfuture.com/2009/05/rna-engineered-to-count-while-in-living.html | 18:23 |
bryan_ | nsh: paperlink or it didn't happen :) | 18:23 |
nsh | you find it | 18:23 |
bryan_ | bah | 18:23 |
genehacker | nsh you reddit? | 18:23 |
* nsh is betting this will lead to intra-cellular turing-completeness within one decade and 5 geniuses | 18:24 | |
nsh | i read reddit, yeah | 18:24 |
fenn | nsh: they didnt even use bit encoding | 18:24 |
genehacker | you didn | 18:24 |
genehacker | 't | 18:24 |
genehacker | test the output? | 18:24 |
nsh | "The RTC Counter can be "reset" to start counting the same series over again, but it has no way to "remember" what it has counted. The team's second counter, called the DIC (DNA Invertase Cascade) Counter, can encode digital memory, storing a series of "bits" of information." | 18:25 |
fenn | that's just journalist bullshit. it counts in series | 18:26 |
genehacker | noise | 18:27 |
genehacker | biological systems are damn noisy | 18:27 |
fenn | ideally you'd have gray coding for noise resistance, but binary would prove that it's scalable | 18:27 |
genehacker | look at what you see | 18:27 |
genehacker | notice the noise? | 18:27 |
nsh | noted thanks, fenn | 18:33 |
genehacker | you mean something like trinary code? | 18:35 |
genehacker | ternary I mean | 18:35 |
genehacker | you know the russians built a ternary computer? | 18:35 |
fenn | in binary it's easy to get the wrong number by a power of 2^n where n is random | 18:39 |
fenn | +- 2^n | 18:39 |
nsh | ternary is in some ways more efficient than binary for computing as it's closest to base e, which simplifies multiplication | 18:39 |
nsh | if i recall correctly | 18:39 |
fenn | gray code makes it so that those sorts of errors can't happen | 18:39 |
fenn | heh nsh why not just use e-nary :) | 18:39 |
nsh | however, their are electronic disadvantages that are considered to outweigh the benefits of ternary on the physical layer | 18:39 |
nsh | word, i'll get right onto my transcendental EPROM ;-) | 18:40 |
nsh | (would like to see what happens if by some esoteric result in physics that becomes possible...) | 18:41 |
fenn | lots of information theory already talks in terms of nats | 18:41 |
nsh | interesting, know any examples off-hand? | 18:41 |
fenn | er, no | 18:41 |
nsh | np | 18:42 |
fenn | http://en.wikipedia.org/wiki/Nat_(information) | 18:42 |
nsh | on it | 18:42 |
genehacker | explain graycode | 18:42 |
genehacker | if you don't mind | 18:42 |
genehacker | I'm sewing right now | 18:43 |
nsh | because, they say you rip what you sew | 18:45 |
nsh | ok, i'll go to sleep... | 18:45 |
fenn | genehacker: you know about absolute encoders right? | 18:46 |
genehacker | believe me it's true | 18:46 |
genehacker | no | 18:46 |
fenn | oh ffs what do they teach you in school | 18:46 |
fenn | ok an optical encoder is like on a ball mouse | 18:46 |
genehacker | oh yeah | 18:47 |
fenn | when you turn the wheel a slot interrupts a beam of light | 18:47 |
genehacker | yeah I know that | 18:47 |
fenn | that is an incremental encoder, it only keeps track of the least significant bit | 18:47 |
fenn | an absolute encoder stores the whole byte (or whatever number of bits) | 18:47 |
fenn | that way when you boot up your robot it knows where it is already, without having to go through some kind of initialization procedure | 18:47 |
fenn | ok here are two absolute encoders http://sub.allaboutcircuits.com/images/quiz/01237x01.png | 18:48 |
fenn | the one on the left is binary, the one on the right is gray code | 18:48 |
fenn | notice that the binary has places where a large number of bits change at once | 18:48 |
fenn | but the gray code only changes one at a time | 18:48 |
bryan_ | heh | 18:50 |
bryan_ | http://sata.serveftp.org/~bryan/spiral_results/ | 18:50 |
fenn | when you're sending a signal down a noisy bus, you can confuse the receiving end into thinking that you're suddenly at 255, but a gray code receiver would know better and discard the result as noise | 18:50 |
bryan_ | imagej rocks for this sort of thing | 18:50 |
fenn | because a large number of bits would have to change at once | 18:50 |
bryan_ | these kids were counting the cells by hand | 18:50 |
bryan_ | fenn: will you be around for a few minutes longer? | 18:51 |
fenn | ya | 18:51 |
bryan_ | joseph might be bringing in some guests | 18:51 |
fenn | hm. | 18:51 |
bryan_ | for his conference thingy | 18:51 |
fenn | hey that's not a .xls file! | 18:53 |
fenn | it's tab-delimited | 18:54 |
genehacker | yeah they still count cells by hand | 18:55 |
fenn | fools! | 18:55 |
fenn | that's what a flow cytometer is for | 18:55 |
genehacker | you get one of those clicker things an click away | 18:55 |
bryan_ | seriously though, wtf | 18:55 |
genehacker | for one minute | 18:55 |
bryan_ | one minute of doodling around with imagej and apt-get and the problem is solved | 18:56 |
bryan_ | stephen was going to sit around counting them by hand | 18:56 |
bryan_ | with his eyes pressed up to the 'scope | 18:56 |
genehacker | flow cytometers are expensive, clickers are cheap, microscopes are abundant, and undergrads need jobs | 18:56 |
genehacker | imagej some stuff | 18:56 |
fenn | genehacker: you're fired | 18:56 |
bryan_ | heh | 18:56 |
bryan_ | fenn: were we ever paying him? | 18:57 |
fenn | now he gets negative cash | 18:57 |
* bryan_ checks the group's bank account funds | 18:57 | |
bryan_ | it's kinda dry | 18:57 |
genehacker | I thought you guy's didn't use cash you used wuffie? | 18:57 |
fenn | ah that's because i've been funneling into offshore banks | 18:57 |
genehacker | good I hear micronesian stone coins are a very stable form of currency | 18:58 |
fenn | millions of years baby | 18:58 |
fenn | copper barely lasts a century when exposed to the elements | 18:58 |
* fenn mutters something about glass optical coins with digital signatures | 18:59 | |
genehacker | so put it in a container in the vacuum of space | 18:59 |
genehacker | DVDs | 18:59 |
fenn | you certainly don't understand the whole 'buried treasure' thing | 19:00 |
bryan_ | ok, joseph's not coming | 19:00 |
bryan_ | wah | 19:00 |
genehacker | the container is an iron asteroid | 19:00 |
genehacker | thats how space pirates do it | 19:00 |
genehacker | http://www.space.com/php/multimedia/imagedisplay/img_display.php?pic=071009-technovel-spacemo-02.jpg&cap=Quasi+Universal+Intergalactic+Denomination+or+QUID+is+the+first+currency+of+its+kind+in+the+universe.+Credit%3A+Business+Wire | 19:05 |
genehacker | SPACE COINS | 19:05 |
fenn | you know, with RFID that wouldnt be a terrible idea | 19:08 |
fenn | but they shouldnt be shaped like coins | 19:09 |
fenn | little stuff like that gets lost too easily in zero gravity | 19:09 |
fenn | you'd want something like a carabiner i think | 19:09 |
genehacker | RFID= easily damagable by space radiation | 19:10 |
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genehacker | unless you make the chips big and on sapphire... | 19:10 |
genehacker | hmmm | 19:10 |
fenn | i guess the question is 'is the token the unit of exchange, or the number' | 19:11 |
fenn | erm, number = cryptographic key | 19:11 |
genehacker | if you are far from banks on earth and it takes 20 minutes to validate your key then people might exploit it | 19:12 |
fenn | no, not server based | 19:12 |
fenn | that's a terrible idea on any planet | 19:12 |
fenn | transactions have to be self contained | 19:13 |
genehacker | when it doubt dike it out | 19:13 |
genehacker | would you even need money on say an asteroid full of resources? | 19:13 |
genehacker | if you had a super factory capable of making damn near anything? | 19:14 |
fenn | depends whether you need money or not | 19:14 |
genehacker | how about mechanical bump pattern? | 19:15 |
fenn | like the fiducials on http://reactivision.sourceforge.net/ | 19:17 |
ultraleibniz | back | 19:31 |
ultraleibniz | fenn: what's the most expensive CFD program that you know of | 19:31 |
genehacker | [commercial CFD program here] | 19:32 |
ultraleibniz | well yeah | 19:34 |
fenn | uh. well probably the most famous one, so that would be NASTRAN | 19:34 |
fenn | hmm no that's not very expensive | 19:34 |
fenn | i give up | 19:35 |
fenn | i dont know any cfd programs | 19:35 |
ultraleibniz | ANSYS has some stuff apparently | 20:23 |
ultraleibniz | CFD-CAD is another name for something (wtf?) | 20:23 |
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drazak_ | kanzure: should I find supporting papers and post my microfluidics sequencer to diybio? or should I keep that crap to myself? | 21:06 |
ultraleibniz | drazak_: I recommend posting | 21:51 |
drazak_ | well | 21:51 |
ultraleibniz | also, grub still fails and I can't figure out what's wrong with the limited command line utility it's providing me | 21:51 |
drazak_ | what error? | 21:51 |
ultraleibniz | there is no error | 21:51 |
ultraleibniz | it just doesn't boot ubuntu | 21:51 |
ultraleibniz | although it boots windows.. | 21:51 |
drazak_ | well that's just chainloader +1, that's easy | 21:52 |
ultraleibniz | what? | 21:52 |
drazak_ | what do you have for your lines for booting ubuntu? | 21:52 |
drazak_ | the line in the grub config file for booting windows | 21:52 |
ultraleibniz | erm, I don't know it off the top of my head and it's currently going through some memory diagnostic thingy provided by microsoft | 21:52 |
ultraleibniz | so I'll grab it in a few minutes | 21:53 |
drazak_ | lol | 21:53 |
fenn | "Setup would notify pilots when brain overload is causing dangerous levels of stress, fatigue and distraction." | 22:29 |
fenn | i didnt know 'brain overload' was a technical term | 22:30 |
fenn | The researchers are using functional near infrared spectroscopy (fNIRS) and other imaging technology to measure blood flow in the brain's cortex and the concentration of oxygen in the blood. This emerging technology offers a non-invasive, safe, portable and inexpensive method for monitoring indicators of neural activity | 22:31 |
genehacker | interesting | 23:41 |
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