2009-06-11.log

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kanzure22:16:01 omg/user: ..."Using this as an interesting starting point, the authors ran another series of 201 integrations where 07:11
kanzure                   the semi-major axis of Mars was changed by up to 30 mm. Within 100Myr of starting these integrations, five07:11
kanzure                    of the simulations resulted in Mars being ejected from the solar system."                                07:11
kanzure22:16:21 omg/user: "All of the remaining 196 cases resulted in various collisions between Earth, Mars, Venus, Mercury, and/or07:11
kanzure                    the Sun."                                                                                                07:11
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kanzure            Harold Stephen Black’s 1927 famous patent that he wrote on a copy of the New07:45
kanzureYork Times)07:45
kanzurehttp://en.wikibooks.org/wiki/Control_Systems/State-Space_Equations07:53
kanzure"I's & C's with integral causality"07:58
kanzureoh, sorry07:58
kanzureindependent energy storage elements: I's & C's with integral causality07:59
kanzuredependent energy storage elements: I's & C's with derivative causality07:59
kanzurehttp://www.me.utexas.edu/~bryant/courses/me344/DownloadFiles/LectureNotes/StateEqns.pdf08:00
kanzurethat was useful.08:00
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kanzure"causal analysis"08:34
kanzureThe differential equations describing the dynamics of the system are written in terms of the states of the system. All storage elements (I and C) correspond to stored state variables (P for momentum and Q for displacement, respectively) and equations are written for their time derivatives (i.e. effort and flow). These equations are derived in four steps as described below.08:37
kanzure   1.08:37
kanzure      Observe what the elements (sources, I's, C's, and R's) are giving to the system and write down their equations looking at the causalities and using variables for strong bonds.08:37
kanzure   2.08:37
kanzure      Write down equations for the junctions and the two-port elements for the variables for the strong bonds.08:37
kanzure   3.08:37
kanzure      Replace the variables, which are expressed in terms of states in other equations. Continue sorting and replacement till the right side of the entire set of equations are expressed in terms of states and system parameters only.08:37
kanzure   4.08:37
kanzure      If some equations are still not completely reduced, there is the existence of some kind of a loop (algebraic loop, causal loop or differential causality, as shall be discussed later). Try solving those as a set of linear equations either through substitution or matrix inversion.08:37
kanzure And finally, erase all trivial equations other than those for derivatives of state variables and write them in terms of state variables. 08:38
kanzurehttp://www.bondgraph.info/about.html#eqn08:38
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kanzureok it seems to be working today10:09
kanzuredoes anyone know where I should put my server now that I can't keep it at home?10:09
kanzurefenn: http://www.cs.utexas.edu/~suriya/UT-wireless/10:09
kanzureaha. disabling dynamic word wrap helps in kwrite. 10:33
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kanzurehttp://www.bondgraph.info/about.html has broken links but the images are actually there. so don't be fooled. http://adl.serveftp.org/papers/bondgraphs/eqn/www.bondgraph.info/about.html has the fixed version, or something16:04
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--- Log closed Thu Jun 11 17:42:57 2009
--- Log opened Thu Jun 11 19:26:48 2009
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kanzureblargh19:26
fennyou didnt miss anything19:27
kanzuremy soul19:27
kanzuretodo: check if the morning zipping of GraphSynth 2 works.19:29
drazak_I'm a h+ist that believes in the soul, just a little weird19:30
kanzurehttp://www.xmms.org/files/1.2.x/xmms-1.2.11.tar.bz219:30
kanzuredrazak_: sorry, what?19:30
kanzurewhat do you believe in? my translators are down.19:30
fenndrazak_: it's a useful concept that gains much traction among the gentiles19:30
fennsee maslow's hierarchy of needs19:31
drazak_seen it19:31
drazak_I should restate, also19:31
drazak_I believe in shit like psionguild.org19:31
fennwhatever that is, you probably shouldn't have said so19:32
drazak_probably :P19:32
fenni built several orgone accumulator/amplifiers but they didnt seem to do anything19:35
fennor at least all the weird coincidences turned out really sucky for me personally19:36
drazak_well, I know nothing about that19:37
fennit's basically the same thing, but with toys19:37
drazak_right19:38
drazak_that's called radionics19:38
drazak_in our group19:39
drazak_I know shit for shinola about radionics19:39
fennradionics is more like quantum entanglement stuff19:39
fennthe stuff i was doing was supposed to be like holography19:39
fennit did make some interesting ice crystals19:39
fennbut that's sort of hard to prove causality19:40
fennanyway i've taken up diax's rake, which says to believe in something because it's right, not because you like it19:41
fennnot sure what the equivalent philosophy is called in earth terms19:42
kanzurewas diax the retarded brother of occam?19:47
drazak_he must have cut himself with his razor, shaving19:49
fennhe was gardening outside the temple, watching the numerologists play dice, then one day he just snapped and beat the crap out of them with his rake19:50
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genehackerholy cow19:56
genehackerhigh altitude wind power could be cheaper than coal or natural gas19:56
kanzurehehe, sata might vouch for me to get into any class despite pre-reqs19:57
genehackerheh19:58
genehackerawesome19:58
kanzurewhat should I take19:58
genehackeremailed you19:58
kanzureM 340L ?19:59
genehackeryes19:59
genehackerwhat classes are you taking?19:59
kanzureM408D, CH301, ME205.19:59
genehackerME205?19:59
kanzureyeah20:00
genehackerdang you haven't even started taking fun classes yet20:00
kanzureit's really really boring20:00
genehackerchem 301?20:00
kanzureyes :(20:00
genehackeris that O chem?20:00
kanzureno20:00
kanzureI don't qualify for o-chem.20:00
kanzuremuch less p-chem20:00
genehackeryou know what I think this is a conspiracy by the luddites of the world to hold people like us back20:01
genehackerluckily I found a backdoor around it20:01
kanzurepre-reqs suck.20:01
kanzurewhat is the backdoor?20:01
genehackerto take college in highschool20:01
kanzurethat doesn't work if your parents don't let you20:02
fennhttp://192.168.1.86/mp320:02
genehackeryeah and there is only one in texas so20:02
kanzurenot true at all, genehacker 20:02
genehackerok20:02
kanzurethere are many high schools within universities20:02
kanzureand many community colleges20:02
kanzurebut it doesn't seem that parents are interested in letting their kids attend those classes, for some reason20:02
genehackerwell anyway you should figure out how to automate your homework20:03
kanzureit only works if I know how to do the homework in the first place20:03
genehackerbtw are there any graph grammars for english?20:03
kanzureyou mean string grammars? like, regular linguistic grammers20:03
kanzure*grammars20:03
kanzureack20:03
genehackeryeah20:03
kanzureyeah it's defined in the dictionary20:03
genehackerI'm wondering if it's possible to make an automatic arguing machine20:03
kanzureyou mean, me?20:04
genehackerarguments are somewhat algorithmic20:04
genehackerno20:04
kanzureone time I came up with a way to make a bullshit machine20:04
fenngraph grammars for english, heh20:04
kanzureautomatic fallacious argument generator20:04
drazak_kanzure: I did ap chem in hs, I get to start with ochem my first year20:04
kanzuredrazak_: ap chem conflicted with ap physics in my school.20:04
genehackerI'm thinking of a way to pass english class and automatically disprove online kooks20:04
kanzureand the pre-req dependency graph thingy made it impossible to take it earlier20:04
fennthis is a good one http://192.168.1.86/mp3/Ruth White/Short Circuits/09-solfeggietto.mp320:05
fennbut the rest of that is painful to listen to20:05
genehackeryour link is dead fenn20:05
fennlocal net20:05
genehackeroh20:05
genehackerwhere?20:05
fennuh, here to there *points*20:06
genehackeralso I got a question about automatic design20:06
kanzureyeah?20:06
genehackerso let's say I'm automatically designing a high altitude wind power system20:06
kanzurewhat is the method of automatic design that you are using?20:06
genehackerhow do I get the system to take into account factors like storms and ice accumulation on the blades20:07
kanzurewhat system20:07
genehackerwithout a human telling it about it20:07
genehackerany system20:07
kanzureum. what?20:08
kanzureyou mean20:08
kanzure"how do you make it take something into account that you don't tell it about"20:08
genehackerhow do you take into account factors that are not readily evident20:08
kanzurethat's a good question. how do you do that non-automatically anyway?20:09
genehackerthings like vibration loosing parts20:09
kanzureonce you know how to do it, you can typically automate it20:09
genehackerI don't know20:09
drazak_kanzure: I'm doing ap physics next year20:09
kanzuredrazak_: get out of high school or else.20:10
* drazak_ shrugs20:10
drazak_whatever20:10
kanzuregenehacker: what I'm currently working on at the moment is a method of extracting state equations for a particular machine design20:11
kanzureso if you have a resistor hooked up to a motor, what's the equation?20:11
kanzureand if you have a resistor hooked up in parallel to another resistor, what's the equation? (yay kirchoff)20:11
kanzurethese aren't external environmental variables of course20:12
kanzurebut I think internal stuff is more important for starters20:12
drazak_wow, my dad might not let me go to the lab in boston, because people in the family have issues20:12
kanzurejust show up20:12
drazak_right20:12
drazak_go 800mi20:12
drazak_from my parents20:12
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drazak_with no money20:12
kanzuregenehacker: what I'm currently working on at the moment is a method of extracting state equations for a particular machine design20:13
kanzureso if you have a resistor hooked up to a motor, what's the equation?20:13
kanzureand if you have a resistor hooked up in parallel to another resistor, what's the equation? (yay kirchoff)20:13
kanzurethese aren't external environmental variables of course20:13
kanzurebut I think internal stuff is more important for starters20:13
genehacker_how do I know this? well I saw a pic with what happened to an airplane that went through a thunderstorm20:13
drazak_1/R+1/R right?20:13
genehacker_how do we get a machine to do that20:13
kanzuregenehacker: the search term seems to be "bond graphs" or "linear graphs"20:13
kanzuredrazak_: Kirchoff's voltage law (KVL) and Kirchoff's current law (KCL)20:14
kanzurehttp://adl.serveftp.org/papers/bondgraphs/20:14
drazak_right20:14
genehacker_or with the case of parts vibrating off, how do we get machines to know whether they need to do high computational power testing20:14
kanzuregenehacker: see this: http://adl.serveftp.org/papers/bondgraphs/eqn/www.bondgraph.info/about.html20:14
genehacker_just wondering20:14
kanzuregenehacker: you mean, "are there certain scenarios where it is definitely known that more advanced models are going to be needed" ?20:14
kanzureI think anything involving the maxwell equations might fit under that category20:15
kanzurebut that's just because I'm bullshitting20:15
genehacker_so how does the machine know that it needs to do see if it needs to do complex FEM simulation to see if vibration from say a tire is going to destroy a part?20:17
kanzurefenn: Broadcom Corporation NetXtreme BCM5764M Gigabit Ethernet PCIe (rev 10)20:17
kanzurewell, there's my ethernet20:17
kanzure"Intel Corporation Wireless WiFi Link 5100"20:17
genehacker_will automated design always be semiautomatic because of factors the machine didn't take into account20:17
kanzurehow would it take into account things that are impossible to take into account20:18
kanzureI don't really understand what you're trying to get at20:18
kanzurebut yeah, there are complex simulations you can do with FEM20:18
kanzureso let's take for instance a simple spring-and-mass model or something20:18
kanzureand you can model a particular beam as a collection of parts 20:18
kanzurerather than a single part20:18
genehacker_humans would take it into account, because they've heard about these things20:18
genehacker_err might?20:18
kanzurebut not all humans because some huamns (like me) don't know about them20:19
kanzure*humans20:19
kanzureanyway,20:19
kanzurethe beam model would be an example of a part that could be complexificationized into an FEM model20:19
kanzureit's kind of like a "meshing" step20:19
kanzurebut this doesn't introduce new variables into the equation .. just more of the same :)20:19
genehacker_so how does a machine do it's own real world testing?20:19
kanzureand so it creates a higher-order model or something20:19
kanzuregenehacker: hod lispon had a machine doing real world testing 20:19
kanzurebasically what he did was have a program that would make hypotheses and predictions about the machine itself20:20
kanzurebecause it didn't know how many legs it had or something20:20
kanzureso it would try to formulate the best working model for movement or something20:20
kanzureso there was a simulation version and a real-world version for a particular machine with many linear actuators20:20
genehacker_so let's say a gas turbine fails20:20
kanzureit looked hideous IIRC20:20
genehacker_how does the machine figure out why20:20
kanzureby following a procedure20:20
genehacker_the gas turbine has heavily abraded blades20:21
kanzurewhat procedures do engineers use?20:21
kanzurethose are the procedures that the machine would use.20:21
genehacker_what about things like sounds the turbine makes?20:22
genehacker_patterns of abrasion20:22
genehacker_this sounds like a bad bearing, there's more abrasion here because a part is fragmenting20:23
fenni'm afraid i've been contaminated by "on intelligence" so i can't provide the traditional "hard AI" answer right now20:24
genehacker_will we have to give machines experience packs?20:24
kanzureyes but what do you mean by experience packs20:25
genehacker_a whole bunch of data from a whole bunch of different scenarios20:26
kanzurewe have to encode engineering knowledge into computational tools20:26
kanzureso somebody has to learn it once20:26
kanzurethen they have to write a program20:26
kanzurethat's generally how automated design works at the moment20:26
fennsupposedly (according to kanzure) there's a giant flowchart that the military goes through to figure out what broke when somebody blew up their plane20:27
genehacker_then you run into the problem of having something for everything20:27
kanzurewhy would you have that problem?20:27
fennyou mean lack of abstraction?20:27
kanzureit should be able to automatically figure out what something to use in the first place20:27
genehacker_I think so20:27
kanzureso what's the problem?20:27
genehacker_how do we take the human out20:28
kanzureby harvesting their brains (for now)20:28
fennreal world testing is not necessarily about failure analysis, it's about making sure the machine functions as intended20:28
genehacker_hmmm...20:28
fennso there's a limited number of things you have to check (the dependencies/requirements of the machine)20:28
fenner, and outputs too20:28
genehacker_do they have any good scans of people's brains yet?20:28
fennno20:29
genehacker_damn20:29
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fenni'm still rooting for the nanobots myself20:29
genehacker_how do we make a machine capable of encoding engineering knowledge on it's own20:30
kanzureI don't know what that means though20:31
kanzurewhat is "engineering knowledge" and how do you know if you have it or not20:31
kanzurethat sounds very confusing, genehacker_ 20:31
genehacker_or should we just diagonal cutter it out and have people input the knowledge20:31
genehacker_good point20:31
genehacker_how does automatic design work?20:32
kanzureit doesn't20:32
kanzureit is vaguely defined20:32
kanzureat the moment we have some tools for creating different assemblies of different components20:32
kanzurebut then no way to figure out what the system equations are20:32
genehacker_but not the components themselves?20:32
kanzurenot anything good20:33
kanzurethere's some crap, but you can't use it because it's all academic bullshit20:33
kanzureand you can't use it because it doesn't capture the right information anyway20:33
kanzurealthough there was some stuff from A-DESIGN (a component library) that was from a catalog20:33
kanzurethat was actually useful20:33
genehacker_so let me put it another way20:33
kanzureunfortunately it doesn't run anymore20:33
genehacker_how do we make a machine that can tell the tone of a paragraph20:33
kanzurewhat is tone?20:34
genehacker_the mood or feeling of a literary work, as the author gives20:34
kanzurethat didn't help20:34
genehacker_yeah it doesn't20:34
genehacker_the example in english class was the usage of the word peruse20:35
kanzurewhy are you paying for that class20:36
genehacker_peruse is somewhat antiquated so using it makes you sound like you're trying to sound professional but failing at it20:37
genehacker_how do we get machines to know things like that?20:37
kanzureaccording to who though20:37
kanzureuh20:37
kanzurewell it's bullshit so I don't think it counts20:37
kanzureit's not really anything that matters or is right ..20:37
kanzureit's just some crap that they are making you do20:37
genehacker_yeah it is20:38
genehacker_so how do we get a machine to know if it is sounding like it's joking ?20:38
kanzureare you reading questions from your homework? if so, stop it.20:39
fenngenehacker_: read "on intelligence" which i can provide the pdf if you like20:39
fennor not20:39
genehacker_my solution is to have the machine look at word usage patterns from websites lots of people go to20:39
genehacker_and copy those20:40
fennever seen megahal? (hidden markov model chatbot)20:41
genehacker_no20:41
fennits not as cool as you think20:41
fennthere is no magic bullet20:41
genehacker_indeed there isn't20:41
genehacker_you'd probably end up with a lot of slang20:41
genehacker_can we get machines to read papers and extract useful information from them is what i'm thinking20:42
genehacker_semantic web stuff20:43
kanzureyeah I have some stuff for automatically searching for interesting papers20:43
kanzurebut it doesn't work yet :)20:43
kanzurebut it also isn't "analyzing english"- it doesn't have to do that ..20:43
kanzureit just needs to go over the citation/reference-topology and look for regularities in "really super interesting mountains of papers" or whatever20:43
kanzure(this kind of goes back to my google scholar "search assistant" plans)20:44
genehacker_so do we just a whole lot of people to "wiki up" knowledge for an automatic design engine?20:45
kanzurehell no :)20:46
kanzurebut20:46
kanzurelook into debian packages20:46
kanzure(google it)20:46
kanzurecolorollary to the anthropic principle: it's weird that there is no magic bullet.20:47
genehacker_well do we have any other approach that works?20:50
fennSCIENCE!20:51
drazak_yes20:52
genehacker_well do you have a framework for SKDB yet?20:55
kanzurealmost there. I can taste it.20:55
kanzurethe bond graph and linear graph stuff is like the last on the list20:55
fennnot for the next 3 months20:55
fenntoo busy with ADL crap20:55
genehacker_HOLY COW20:56
genehacker_wolfram alpha knows molecules20:56
genehacker_http://www06.wolframalpha.com/input/?i=pentaerythritol20:58
genehacker_has handy property data20:58
genehacker_perhaps we could use wolfram20:59
katsmeow-afkTo see full output you need to enable Javascript in your browser21:00
genehacker_what?21:01
katsmeow-afkTo see full output you need to enable Javascript in your browser21:01
genehacker_I see everything21:01
katsmeow-afkok21:02
genehacker_I have21:03
genehacker_kanzure how do I use the library proxy?21:03
kanzurehttp://ezproxy.lib.utexas.edu/login?url=http://scholar.google.com/21:04
katsmeow-afkwolfram screws up "cow", as do most engines, "placental" is not a term one would use to ask where the cows are at a state fair21:04
genehacker_woohoo21:05
genehacker_I don't care about cows21:05
katsmeow-afkwants an eid and password21:05
katsmeow-afki don't care a lot about cows, but i like accuracy in thedata for things i do care about, but know less about21:05
katsmeow-afkif it cannot get "cow" right, how do i know it got something else right?21:06
genehacker_here's the deal21:07
genehacker_Wolfram alpha knows information about chemicals21:07
kanzure"knows" ?21:07
kanzurewhat are you talking about21:07
kanzureit's just a database21:07
genehacker_guess so21:08
* katsmeow-afk backs outa the channel s l o w l y21:08
genehacker_but you know all those papers on GNA phosphoramidite synthesis?21:08
kanzurewhat about it21:09
genehacker_well now I can sort of understand them21:09
kanzurewhy not just use chemspider21:09
kanzureor wikipedia21:09
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genehacker_http://www06.wolframalpha.com/input/?i=4%2C5-dicyanoimidazole21:11
genehacker_alpha uses an awful lot of sources21:11
genehacker_http://en.wikipedia.org/w/index.php?title=Special%3ASearch&search=4%2C5-dicyanoimidazole&go=Go21:13
genehacker_that's why21:13
kanzurewhat about chemspider21:13
genehacker_trying it21:14
genehacker_that's much better than wolfram21:19
genehacker_but it doesn't tell me how to make it21:19
genehacker_and wolfram doesn't either21:20
genehacker_is there anything that does?21:22
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fennhow about an organic chemist21:34
DrTreadorganic chemists smell bad. :(21:34
fennyou could say that about most people21:35
genehacker_heh21:35
genehacker_organic chemists also tend to die of horrible nasty cancers21:35
DrTreadtrue.21:35
DrTreadchemists have the highest suicide rate amongst the sciences.21:36
genehacker_hmmm...21:37
genehacker_now how do I make some O6 benzylguanine?21:37
DrTreadavoids the cancer problem21:37
DrTreadfind an organic chemist.21:38
genehacker_or use the internet21:39
genehacker_yay google21:40
DrTreadok, how do you do it?21:41
genehacker_what?21:42
genehacker_I just type in a chemical name into google with the word synthesis after it21:42
DrTreadmake benzyl guanine21:42
DrTreadI figures that. sorry, I am on mobil phone. don't want to google. 21:43
kanzurehello DrTread 21:44
DrTreadhello, kanzure. 21:45
genehacker_tornado watch21:46
genehacker_???21:46
DrTreadkanzure, had any interest in building a DIY lazor cutter?21:46
genehacker_ok this benzylguanine stuff is the main component of GNA phosphoramidites21:46
genehacker_YES21:46
DrTreadORLY? Ok. let's build. 21:47
fenncan 100W do thin metal?21:47
genehacker_I believe so fenn21:47
DrTreadbut first, $2000 in parts21:47
genehacker_yes21:48
DrTreadmeh. not really. but how thin & what metal?21:48
fennstainless, say 0.005"21:48
genehacker_ponoko21:48
genehacker_what ponoko has21:48
DrTreadstainless, no. Al, yes21:48
fenni'd expect Al to be harder to cut21:49
fennhigher heat dissipation21:49
fennand more reflective21:49
DrTreadboth of them need a blackener. 21:49
genehacker_http://www.ponoko.com/make-and-sell/materials21:49
genehacker_ponoko got rid of metal?21:49
genehacker_DAMN YOU PONOKO!21:50
DrTreadoh noze!21:50
genehacker_Now I can't make a stirling engine business card21:50
DrTreadOnline Metals or ASAP Source21:50
DrTreadLOL21:51
* fenn snickers @ windows crash on news/weather channel21:51
genehacker_oh noes!21:51
genehacker_tornado must have hit it21:51
DrTreadthe double wall cloud was scary. no tornados here @ 40th & Guadalupe21:52
genehacker_dang21:53
genehacker_that's not too far from where I am21:53
DrTreadhanging out with friends here. meanwhile, tornado is hitting my house in Bastrop. 21:55
genehacker_that sucks21:57
DrTreadwell, I don't know that for sure. 21:57
genehacker_hmm... patents on how to make certain chemicals21:59
genehacker_useful21:59
DrTreadexpired patents?21:59
genehacker_don't know22:00
genehacker_but it tells how to synthesize certain precursor chemicals necessary for GNA phosphoramidites22:00
DrTreadpatents don't mix well with open source. :-(22:00
genehacker_it doesn't matter because we aren't selling stuff22:01
genehacker_you know what I want to do right?22:01
kanzureit does matter though22:01
kanzurebecause they have the guns22:01
kanzureand will shoot you22:01
genehacker_I want to make DNA synthesizer22:01
DrTreadHmmmm. ask your lawyers. 22:01
genehacker_it's from 199722:01
genehacker_well they can't stop bittorrent?22:02
genehacker_so do you know what basic machines are involved in organic chemistry?22:02
DrTreadtrue. but chem labs move slower than hax0rz22:02
genehacker_IE distillers and stuff22:03
DrTreadI do. 22:03
genehacker_which is why I want to make a tiny chemistry lab that fits on a desktop22:03
genehacker_you do?22:03
genehacker_mind elaborating?22:03
DrTreadI do know someone who has that equipment. 22:03
genehacker_I don't want to borrow the equipment22:03
DrTreadare enzymes involved in the synthesis?22:04
genehacker_I want to know what they do 22:04
genehacker_unfortunately not22:04
DrTreadah. 22:04
genehacker_just a whole bunch of crazy stuff about mixing this and that in different solvents and atmospheres22:04
genehacker_ or something like that22:04
DrTreadyes, well, we can discuss that over coffee. I'd 22:05
DrTreadneed details of the synthesis. 22:05
genehacker_hold up22:06
genehacker_http://www.patentstorm.us/patents/5663338/description.html22:06
DrTreadhard to do on my iPhone. :)22:06
genehacker_(S)-9-(3-(4,4′-Dimethoxytrityloxy)-2-hydroxypropyl)-O6-benzylguanine22:07
genehacker_(3). Compound 1 (3.10 g, 12.8 mmol) was partially22:07
genehacker_dissolved in anhydrous DMF (25.0 mL) under a nitrogen atmosphere.22:07
genehacker_NaH was added (105 mg, 2.63 mmol, 60% in mineral oil),22:07
genehacker_and the solution was allowed to stir under nitrogen for 1 h. In a22:07
genehacker_separate flask, compound 2 (4.60 g, 12.2 mmol) was dissolved in22:07
genehacker_26.0 mL of DMF, added to the first solution, and then heated to 9022:08
genehacker_°C overnight. The next morning, the solution was cooled, all solvent22:08
genehacker_removed, and the resulting oil coevaporated with toluene, redissolved22:08
genehacker_in ethyl acetate, and concentrated again. The product was22:08
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genehacker_purified via column chromatography starting with 2:1:0.01 hexanes/22:08
genehacker_acetone/Et3N, then eluting with 3:2:0.01 hexanes/acetone/Et3N to22:08
genehacker_afford compound 3 as a light yellow foam (3.73 g, 47%):22:08
genehacker_(S)-9-(3-(4,4′-Dimethoxytrityloxy)-2-hydroxypropyl)guanine22:08
genehacker_(4). Compound 3 (3.30 g, 5.3 mmol) and Pd/C (1.70 g, 10%22:08
genehacker_on carbon) were suspended in EtOAc (125 mL), and the solution22:08
genehacker_was purged with nitrogen, then hydrogen, and allowed to stir under22:08
genehacker_a hydrogen atmosphere. After 3 h, TLC showed completion of the22:08
genehacker_reaction, and the mixture was filtered through Celite and washed22:08
genehacker_with 5:1 CH2Cl2/MeOH to afford compound 4 as a tan solid (2.7322:08
genehacker_g, 97%):22:08
genehacker_that's all I'm posting22:08
genehacker_oops22:08
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DrTreadthe website killed the app. 22:09
DrTreadsorry. 22:09
genehacker_was it all the stuff I posted?22:09
DrTreadwill look @ it later, if you email link 22:09
genehacker_are you a chemist of some sort?22:09
DrTreadI am. inorganic. 22:10
genehacker_http://pubs.acs.org/doi/abs/10.1021/jo900365a22:10
genehacker_ah22:10
DrTreadmy company (me) has some modest equipment. 22:11
DrTreadbut I know enough organic chem to do many things. 22:11
genehacker_then you might not be able to figure out our evil world domination plan that involves a GNA synthesizer capable of synthesizer large genomes22:11
genehacker_*synthesizing22:12
DrTreadthat's a bit beyond my ken, yes. 22:12
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genehacker_well It's a bit beyond mine too so...22:14
DrTreadby large, how many gigabases?22:14
genehacker_3 megabases22:14
genehacker_in one run22:14
genehacker_or wait was that gigabases?22:15
DrTreadah. ok. where will you put them? 22:15
genehacker_31,457,280 bp22:15
genehacker_what do you mean?22:16
DrTreadin bacteria? mice? people?22:16
genehacker_So I figured out how to make a DNA synthesizer, but not the chemicals for it22:16
genehacker_anything DrTread22:17
genehacker_*anything I want to put them in22:17
genehacker_but most likely bacteria22:17
genehacker_for compiling enzymes and genes22:17
genehacker_instead of buying them, why not download and compile them?22:17
DrTreadok. it's pretty much impossible to get the chemicals without a business address. 22:18
DrTreadeven simple raw materials. 22:19
genehacker_but if I ever figure out how to make it work, I'd like to synthesize mycoplasma laboratorium and boot it up22:19
genehacker_exactly22:19
genehacker_that's exactly the reason I want to make a tiny chemical factory22:19
DrTreadmove to Brazil. it's not as restrictive there. :)22:19
genehacker_I can't22:20
DrTreaddon't speak portugese?22:20
genehacker_no I don't22:21
DrTreada guy I met a few years ago is from there, but moved to the US. he had to give up his lab. 22:21
genehacker_you see I want a chemical universal constructor22:22
DrTreadit is much easier fir him to build rail guns here than to do chemistry. 22:22
genehacker_wherein we can put in the chemicals we can buy or stuff present and nature and get the stuff we want22:22
DrTreadthere are many ideas for that around. not so many actual machines, however. 22:23
genehacker_really?22:24
DrTreadmolecular machines that use air & acetylene as raw materials22:24
genehacker_that's not what I have in mind22:25
DrTreadyou want to create life in your laboratory?22:26
genehacker_yes22:28
DrTreadmeh. life is overrated. :-/22:28
genehacker_but I'm thinking of having a bunch of miniaturized versions of things like downcells, distilling machines, and what not22:28
genehacker_downs cell requires gravity though it appears though...22:29
DrTreadcenterpetal force is indistinguishable from gravity. 22:30
genehacker_true22:31
DrTreadso if you want to do it in orbit...it's ok 22:31
genehacker_but that adds complexity to things22:32
genehacker_if I'm building a tiny downs cell22:32
genehacker_it may not work very well because it's on scale where gravity doesn't play much of a role22:33
DrTreadah. microfluiducs. ok. 22:33
genehacker_yeah but metallic sodium is fun enough to warrant something large22:34
genehacker_maybe something the size of coke can22:35
DrTreadso use centrifuges.22:35
genehacker_ok22:35
DrTreadyes, the more sodium, the better. 22:35
genehacker_any way could you name a couple of useful chemical processes for producing basic chemicals?22:36
DrTreadcall Signa/Aldrich?22:37
genehacker_or what are some chemicals one must absolutely have?22:37
DrTreadwater22:38
genehacker_that's abundant22:38
genehacker_no need to synthesize it22:38
DrTreadbeyond that, it depends22:38
genehacker_sulfuric acid?22:38
genehacker_potassium perchlorate?22:38
genehacker_Sodium Hydride?22:39
DrTreadnot so much perchlorate. 22:39
DrTreadsodium hydride? nah22:39
genehacker_ammonia of course22:39
DrTreadyes. ethanol, acetone, drying agents22:40
genehacker_those are available so those aren't so bad22:41
DrTreadtrue. but buying too much acetone can land you on DEA watch lists22:41
DrTreadthe country is insane. 22:42
genehacker_sweet22:42
genehacker_bacterial fermentation for producing large quantities of acetone22:43
DrTreadgood. I am all for creating my own economy & industry ouside of the mainstream. 22:44
DrTreadbecause the mainstream isn't doing anything worthwhile. 22:44
genehacker_And I want self-replicating doomsday space robots22:44
DrTreadah, star trek. the uss constellation under the command of commodore decker. 22:46
genehacker_???22:46
DrTreadthe doomsday machine had a hull of neutronium. 22:47
genehacker_oh cool22:47
DrTreadoh, sorry. random STTOS reference. :)22:47
genehacker_hmmm... hydrogen peroxide producing bacteria...22:49
DrTreadcool! peroxide is usually bad. 22:50
genehacker_not to bacteria that produce it and catalase22:51
genehacker_then dump the H2O2 out to kill other bacteria22:51
DrTreadI figured. there has to be a reason to make the stuff. 22:52
DrTreadit's rather expensive to produce if you're an organism. 22:53
genehacker_phosphorous compounds are useful22:54
katsmeow-afki wanna know how to make ammonia from either urine, or atmospheric nitrogen and hydrogen22:55
DrTreadyep. we couldn't do much without it. 22:55
DrTreadsome bacteria are good @ making ammonia out of urine. ever smell a diaper?22:57
* katsmeow-afk nods22:57
DrTreadatmospheric n2 + h2 requires high pressures & a rusty chain as a catalyst. 22:58
katsmeow-afkwhy chain?22:58
DrTreadit fits in the reactor well. 22:59
katsmeow-afko22:59
DrTreadrumor has it that rusty chain was the first catalyst way back when. 23:00
kanzurewell.23:00
kanzurehttp://pygame.org/project/900/23:00
kanzureI'm addicted.23:00
DrTreadcould be a ChemE legend. 23:00
DrTreadoh, kanzure. you should work on more lofty goals. :-)23:01
kanzurenever underestimate the power of randomly generated maps for 2D top-down space shooter thingies23:02
kanzureI was thinking of implementing a way to destroy the walls like in the invaders games23:02
DrTreadkanzure did you get a reply from travis?23:03
kanzureno23:04
genehacker_damn23:04
genehacker_I just had a spider under my microscope but it got away23:05
kanzurethe map generation algorithm kind of sucks23:05
genehacker_oh well23:05
kanzurebut I guess it can be improved23:05
DrTreadI had a paramecium under mine last week23:05
kanzurewho hasn't.23:05
DrTreadit died. :(23:05
genehacker_well why don't you improve the algorithm, change the graphics, and sell it for the iphone23:06
DrTreadI cried. 23:06
genehacker_well you could just grow them in cultures23:06
DrTreadyeah, kanzure. make an iPhone game. make insane $$, then fund our projects. 23:07
kanzuregenehacker_: why are you always about selling stuff on the iphone23:07
genehacker_oh and that mycoplasma laboratorium bacteria? it could be blue23:07
kanzurewhy does everyone assume you can make insane money on the iphone23:07
DrTreadttyl. got to go. 23:07
genehacker_because a small group of people have made lots of money on the iphone and this small group has been highly publicized23:07
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genehacker_well I probably should work on homework23:09
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kanzurepymunk is pretty neat too23:37
kanzurehttp://www.pygame.org/project/780/23:37
kanzurepybox2d is nice too23:42
kanzurealthough the theo jansen mechanism example doesn't work because of some poorly specified bit depth field or something23:48

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