2009-10-18.log

--- Day changed Sun Oct 18 2009
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Utopiah!seen fenn09:31
Utopiahdo you guys want a Supybot instance? for this and publishing daily logs?09:32
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ybitUtopiah: i suppose it couldn't hurt11:15
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kanzureybit: fenn and i were thinking of not sleeping. $50/night looks ok but honestly i think we could do better if we find some transhumans to sleep with.12:27
kanzureybit: togetic seems to be down? 71.228.183.18112:28
kanzureit doesn't seem to be located at ybit.ath.cx either12:28
Utopiahkanzure: do you have a link to fenn sleeping/activity patterns? iirc he even made colorful visuals12:28
kanzureQuantumG is still around and posts frequently to slashdot. percent thinks i'm the devil and will kill all humans indirectly (and "perhaps directly")12:29
kanzurei'll have to go look at the mailbox in a bit. i'm at the wrong location.12:29
kanzureybit: kottke is going to have to find some other friends, 6hr is too long12:30
kanzureUtopiah: http://fennetic.net/sleep/12:30
Utopiahthanks kanzure 12:30
kanzureybit: i was trying to log in to fix your #12:31
kanzureskdb.core.units.UnitError: pi/2 radians: Unknown unit 'pi'12:31
kanzureybit: you should send paper requests also to getarticles@googlegroups.com, and when you get responses, forward the papers to papers@postbiota.org12:32
drazakkanzure: do people not read the most recent posts before the post to diybio?12:39
drazakI repeated 4 times that GFP was a bad idea12:39
kanzurein general they do not read12:43
kanzure(anything)12:43
kanzureeric hunting just repeated pepakura information from over a year ago from open manufacturing, for instance12:43
kanzurethat's something he should have known about back then12:43
drazakthat Cathal guy seems to be pretty on top of everything12:48
drazakit's just some of the other moron on the list that have no fucking clue12:48
drazakabout anything, really12:48
kanzurei can't seem to find any cheap automatic book scanners that either flip pages or take in a stack of pages. kirtas-tech.com sells one used for $100k USD (wtf)12:49
kanzuremy mom made a deal with me- if, in the move, i give up 4 boxes of books, she would buy me a book scanner12:49
drazakget her to spring for the 100k$ one then12:49
drazak:P12:49
kanzureno way, how is it that there's nothing cheaper on ebay?12:50
kanzurei mean, even a $10k used one? really, nothing?12:50
kanzureiirc, xerox machines have this feeder-paper-bay for bulk throughput scanning12:51
kanzurehttp://www.davidco.com/forum/showthread.php?t=9328 suggests an industrial paper cutter (400 pg/cut)12:53
kanzurelots of those on ebay: http://shop.ebay.com/?_from=R40&_trksid=p3907.m38.l1313&_nkw=industrial+paper+cutter&_sacat=See-All-Categories12:54
kanzureand then a pass-through scanner. how do you tell how big the input bay is? (how many pages it can hold without snapping in half or not accepting more paper)?12:56
ybitoh yeah, i forgot percent became a defender of dumbland13:07
ybit12:32 < kanzure> ybit: you should send paper requests also to getarticles@googlegroups.com13:08
ybitah forgot i was on that group13:08
ybitwhy not the lego book scanner?13:08
ybits/dumbland/non-free&open land?13:10
ybitsomething like that13:10
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ybitkanzure: so what's this sabbatical you and fenn have been on? :-)13:47
kanzuremoved down the street13:47
* kanzure suspects ybit isn't metric13:58
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drazakkanzure: what time is it in texas?15:05
ybit3:02 drazak 15:06
ybitcst like mine15:06
ybiter, 3:09 my clocked isn't synced :\15:07
genehackerit is 3:11 pm15:08
ybitdrazak: why do you ask? :-)15:08
drazakbecause I wasn't sure if it was CST or the next one west15:08
ybitgenehacker: what classes are you taking this semester, just curious after you mentioned them last night.15:08
genehackerare you in texas drazak?15:09
drazakno15:09
drazakI'm in ny15:09
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drazakbut I might go to rice or that school you guys are at15:10
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genehackerybit I'm taking hard ones15:10
genehackerthe lab for one is insane15:10
genehackeras in it takes 48 hrs of work to complete a lab assigment15:15
ybitgenehacker: okay, so what courses are you taking? :P15:16
ybitgenehacker: drazak is in buffalo, ny15:16
genehackerwhy do you ask?15:16
ybitbecause i'm curious15:16
genehackerok15:16
genehackermaterials processing, statistics, fluids, materials processing lab, and the horror of the old ones15:17
ybithehe15:18
genehackerI have omitted some though15:18
ybitthat's fine, probably just basics or something like that15:19
ybitthose are what i was interested in15:19
ybiti've never been able to handle more than 16hrs15:20
genehackerI don't think it's more than 16hrs15:20
genehackeryet it's still insane15:20
ybiti'm sure it is15:20
* ybit is looking for multimachine parts list, about to head to the junkyard and round up most of them for my exercise today15:21
genehackera working multimachine?15:22
genehackerimpossible15:22
ybitsurely15:22
genehackerdoe the multimachine just bend stuff?15:22
ybithttp://d.yimg.com/kq/groups/13335163/homepage/name/homepage.jpg?type=sn makes me think it exists15:22
ybit"The MultiMachine is an accurate all-purpose machine tool that can be used as a metal or wood lathe, end mill, horizontal mill, drill press, wood or metal saw or sander, surface grinder and sheet metal "spinner". It can be built by a mechanic using just common hand tools. For machine construction, electricity can be replaced with "elbow grease" and all the necessary material can come from discarded vehicle parts and steel bar."d15:23
genehackerhttp://users.telenet.be/O-tiose/images/sasquatch01.jpg15:25
ybithttp://ybit.ath.cx/misc_docs/How%20to%20build%20a%20multimachine.pdf15:26
ybitomfg, imagine that. http://opensourcemachine.org/the-multimachine/multimachine-video15:35
ybit..it works15:36
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genehackerok15:43
genehackerthen15:43
genehackergood luck15:43
ybitheh, thanks. i figure it's something to play around with afk15:46
genehackeralmost forgot15:47
genehackerI learned of something amazing the other day15:47
genehackeramazing software that does the impossible15:48
genehackersoftware that does fatigue testing in software15:48
ybitgenehacker: link?15:54
ybitor just a name of the program..15:57
ybityou can't leave me hanging with "oh i have this great life-changing secret, well ttyl" :-)15:57
drazaki'm leaving to go to ac/dc in a few15:58
ybitA study in humans published in 2006 hints at a link between16:02
ybitParkinson's and a prolonged exposure to amphetamine in any form (not just16:02
ybitthat prescribed for ADHD).16:02
ybit...Before Parkinson's symptoms such as tremors and16:03
ybitmuscle rigidity appear, however, dopamine's function in the brain must16:03
ybitdecline by 80 to 90 percent, or by about twice as much as what Ricaurte and16:03
ybithis colleagues saw in baboons that were drinking a more moderate dose of the16:03
ybitdrug. And some studies have found no connection between stimulant use and16:03
ybitParkinson's.16:03
genehackerthey feed in electron microscope data and it tells where an engine block will fail16:06
genehackerI have no link16:06
genehackerthat is the problem16:06
genehackerI heard about it from a friend16:06
genehackerbut if we could apply it to skdb it would allow skdb to do pretty much everything16:07
ybitif you could get that friend to recall the name of it, that would be appreciated16:16
drazakmmmm ac/dc16:17
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ybitkanzure: i know you are aware of it, but maybe you have forgotten, if the $10k funding falls through, y-combinator might be an option later on, they will fund you ~$15k for a couple of months so that you can prepare to have a product ready to be presented to VCs.16:39
ybithttp://ycombinator.com/16:39
Utopiahiirc #startups has people with Y-Combinator funding 16:40
ybitthanks Utopiah 16:43
ybit"Heath, everything begins at 9 am both Saturday and Sunday. There will be a16:45
ybitparty Saturday night. Ticket prices are still $150, but go up for each 5016:45
ybitthat we sell. "16:45
* ybit will have to double the dosage of stimulants to be the least bit attentive that early 16:46
ybitor at least 20mg16:46
ybitdrazak: enjoy that concert, represent the channel and do something nerdy 16:47
* ybit wonders who bct, boogles, branstrom, chizu, flamoot, kanzure, ve, and zvader are.16:58
ybit-kanzure16:58
ybiter, s/kanzure/ kardan_ 16:59
branstromFairly recently converted h+ wannabe from Sweden16:59
ybitbranstrom: we're all transhuman wannabes :) 17:00
ybitbranstrom: what are your research interests and hobbies?17:00
branstromI've read a lot of Dennett... Then I read On Intelligence. Then I started reading Overcoming Bias & Less Wrong.17:01
ybitwho here do you know? how did you hear about the channel? do you like cream with your coffee? ;)17:01
branstromI'm working on my GED to get into college and study AGI/neuroscience17:02
branstromDon't know anybody here :)17:02
ybithttp://www.google.com/url?sa=t&source=web&ct=res&cd=2&ved=0CA4QFjAB&url=http%3A%2F%2Fwww.grossmont.edu%2Fbertdill%2Fdocs%2FCollegeWaste.pdf ;; "College is a Waste of Time and Money"17:02
branstromI think I found a link somewhere on a website to this channel. Coffee tastes like donkey poo.17:03
ybitand yet i keep going back to it17:03
ybitit, being college17:04
ybitthink this may be my third time to sit out for a semester17:04
branstromInteresting, I'll take a look at that article.17:05
ybitlet's see.. i've sat out more than that... wow, 3.5 years, total, i've sat out17:05
branstromI'm probably a good fit for college though...17:06
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ybiti fit in well, just get tired of it17:07
kardan_hi ybit, just found your ping but didnt get the context17:10
* katsmeow-afk swaps out all branstrom's coffee17:27
branstromSeems to be a lot of people into DIY biology here17:28
ybitdiy in general17:28
ybitkardan_: was just wondering who you were, research interests, hobbies, etc17:29
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kardanybit: my interest is open source hardware in general: https://we.riseup.net/opensourcehardware17:35
kardanwe develop web applications on rails. crabgrass is one of our projects: crabgrass.riseup.net17:36
ybitkanzure: http://superjared.com/entry/quick-django-benching/17:38
kardanwe still have an open ticket with db specifications by kanzure. unfortunately we could not implement them yet .. too many side projects17:39
ybitinteresting17:39
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branstromOh, I'm coding Rails as well19:25
branstromBeen toying/working with it since 200519:25
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kanzureybit: i got your package21:39
ybito good21:41
ybityou should get another one tomorrow21:41
ybitthey're gifts, ya know, for taking the time to do this. it's to be split with fenn even if he does give you ugly looks while backing up the stuff :P where is he btw?21:42
ybitkanzure21:45
ybitand uh, you might not care for one of them :P i tried to cancel the order but the warehouse had already shipped it within 2 hours of the order o.O so, um, just wing it, pretend like it was useful :P21:49
* ybit is feeling emotiriffic21:50
ybit..ya know because of all the emoticons.. maybe i should stop making up words21:50
katsmeow-afkporque why?21:50
ybit^21:51
katsmeow-afki don't know21:51
katsmeow-afkyou are making emoticons?21:51
ybiti typed 3 of them in one line21:52
ybit21:18 <ybit> "mom i need photos for the site. buy a camera and get a tax-writeoff."  "heath, i've got a better idea, i'm about to buy one of those flip  cameras and upload videos to youtube _and_ you can take stills from  the video." 21:52
ybiti laughed21:52
* katsmeow-afk is gonna unload apache and other webservers for one she made : http://designerthinking.com/images/Euphoria/euv4webserver2.html21:54
katsmeow-afkit's only for local use behind a firewall, etc etc etc, and all those caveats21:54
ybitgrr for having to create html and css bologna21:56
katsmeow-afki used as little as possible for the ftp views, i even used <pre></pre> to avoid css formatting if i could21:57
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genehackernode quake22:18
drazakI'm a little deaf22:28
kanzuretodo: grab  Genome evolution and adaptation in a long-term experiment with Escherichia coli22:32
katsmeow-afkit's in Nature mag, i think22:33
katsmeow-afkyep22:34
katsmeow-afkNature advance online publication 18 October 200922:34
kanzurethere was a paper from this group from a while back about this experiment22:36
kanzureit was what caused the lenski bullshit22:36
kanzureanyway, anna salamon and i once schemed up a way to do this with human stem cell lines22:36
kanzureso that we could do maybe 40,000 generations of selection on stem cells and then boot up the rest of the human at some future date22:36
kanzureso that you don't have to actually have 40,000 generations of offspring living for at least 12+ years each22:37
drazakso you want say22:37
drazak10000 passage stem cells22:37
* drazak laughs22:37
drazakglwt22:37
kanzurepassage?22:38
drazakall immortalized cells start to deform after 500 passages22:38
drazakpassage is when you move the cells from one container to another22:38
drazakusually after 3-6 doublings22:38
katsmeow-afki don't see how you can serialise genetic pressure and atthe same time shorten the evolution time22:38
kanzureno i don't want to move them22:38
drazakyes.. you do...22:38
kanzurebullshit22:38
drazakthey will die if you don't22:38
kanzureyou don't even know my environment22:38
kanzurei think you should stop while you're "ahead"22:38
drazakgo ahead and tell me22:39
katsmeow-afkyea, kanzure has a fenn inhis environment!22:39
kanzureno i mean there's no reason that we have to grow stem cells in a situation where we have to transfer them from plates22:39
kanzurethat's kind of silly for high throughput projects anyway22:39
kanzureand apparently it's also silly for biological reasons too22:39
drazakhigh throughput use large roller bottles22:39
kanzurenot always22:39
drazakalso transfering isn't what kills them22:39
kanzuregood night22:40
drazakyou don't seem to understand22:40
genehackerheiflick limit?22:40
genehackerhayflick22:40
drazakgenehacker: kind of22:40
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drazakgenehacker: it's a little different with stem cells22:41
drazakgenehacker: their chromosomes become no longer diploid22:41
drazakkanzure: so how much cell culture have you actually done?22:41
genehacker2now what books do I read to learn these things would probably be a better question to ask22:42
genehacker2so what do you recommend?22:46
drazakgenehacker: a couple good biochem books22:46
genehacker2ok22:46
drazakI've read like 3 or 4 of them22:46
drazakand I can't pick22:46
drazakif you like medical biochem read stryers22:47
drazakkanzure has stryers22:49
genehacker2ok22:49
genehacker2and these biochemistry books have this sort of information? or is this information that can only be gleaned from laboratory experience?22:51
drazakwell22:52
drazaksome of it is in there22:52
drazakI have yet to find a good book on cell culture22:53
genehacker2go figure22:53
genehacker2it's a developing field22:53
drazakmost cell culture techniques haven't changed in 15 years22:54
genehacker2many deformation processing techniques weren't put into a good book that compiled them for about 30 years22:54
genehacker2I'll see if I can't digest stryers before moving on22:55
drazakyeah22:55
drazakit's big22:55
drazaklike 1700 page22:55
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