| --- Day changed Sat Jun 19 2010 | ||
| jrayhawk | the h+ hivemind has deemed you worthy; prepare yourself for the subsumption | 00:12 |
|---|---|---|
| jrayhawk | you cannot escape | 00:12 |
| QuantumG | kanzure: please do this because I'm lazy? fucking what? | 00:33 |
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| kanzure | hi parolang | 10:03 |
| parolang | hi | 10:04 |
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| Yocttar | sup with the silence today? | 13:17 |
| Yocttar | >.< | 13:17 |
| jrayhawk | bryan got subsumed by the h+ hivemind | 13:18 |
| kanzure | aka email | 13:24 |
| Yocttar | Oo | 13:25 |
| kanzure | cool someone cold called me after seeing my phone number on the youtube video :) | 13:25 |
| Yocttar | heh | 13:26 |
| Yocttar | "Hello, this is john from AT&T, your mobile Internet bill has reached its limit, please note, from this moment on, you Internet service will cost double!" | 13:28 |
| Yocttar | AT&T is some provider in US right? :p | 13:28 |
| jrayhawk | Yeah. One that, in response to increasing bandwidth demands from its network-lock-in of the various iPhones, decided to cut monthly bandwidth limits from 5gig to 2gig and start charging ridiculous amounts for overage. | 13:33 |
| jrayhawk | It's a lot more than "double" though. | 13:33 |
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| kanzure | i'm not sure what my bandwidth limit is on my at&t plan | 13:39 |
| kanzure | i don't have an iphone though | 13:39 |
| kanzure | "bandwidth limit" haha that sounds stupid | 13:39 |
| kanzure | uh, my max downloaded bytes | 13:39 |
| jrayhawk | There was some mention of old plans being grandfathered in, but I haven't really been paying attention. | 13:42 |
| kanzure | the amount of email that my phone downloads is enough to send it over | 13:42 |
| kanzure | some asshole sent me an email today that was just one giant .jpeg image of the text he wrote | 13:42 |
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| kanzure | does anyone recall the difficulties with shrinky dink microfluidics that was reported? | 14:50 |
| kanzure | also, i gave Ian_Daniher a link dump on paper-based microfluidics | 14:51 |
| kanzure | Patterned paper as a platform for inexpensive, low-volume portable | 14:51 |
| kanzure | bioassays - requires photoresist and chromatography paper and UV light | 14:51 |
| kanzure | http://designfiles.org/papers/microfluidics/Patterned%20paper%20as%20a%20platform%20for%20inexpensive,%20low-volume,%20portable%20bioassays%20-%20requires%20photoresist%20and%20chromatography%20paper%20and%20UV%20light%20-%20Whitesides%20-%202006.pdf | 14:51 |
| kanzure | Rapid prototyping of paper-based microfluidics with wax for low-cost portable-bioassay http://designfiles.org/papers/microfluidics/Rapid%20prototyping%20of%20paper-based%20microfluidics%20with%20wax%20for%20low-cost,%20portable%20bioassay.pdf | 14:51 |
| kanzure | Three-dimensional microfluidic devices fabricated in layered paper and tape http://designfiles.org/papers/microfluidics/Three-dimensional%20microfluidic%20devices%20fabricated%20in%20layered%20paper%20and%20tape.pdf | 14:51 |
| kanzure | FLASH: A rapid method for prototyping paper-based microfluidic devices http://designfiles.org/papers/microfluidics/FLASH:%20A%20rapid%20method%20for%20prototyping%20paper-based%20microfluidic%20devices.pdf | 14:51 |
| kanzure | Lab on paper http://designfiles.org/papers/microfluidics/Lab%20on%20paper.pdf | 14:51 |
| kanzure | i should get to this point with microfluidics soon: http://www.youtube.com/watch?v=1HrRuaLFGmY | 14:53 |
| kanzure | at first it looks like the pipette might be providing a force for the liquid to go through the system | 14:54 |
| kanzure | but near the end the pipette is lifted and it looks like it might really be surface tension and capillary action | 14:54 |
| kanzure | heh crazy complexity http://www.youtube.com/watch?v=JvDZh8hmR84 all of /four/ valves | 14:55 |
| kanzure | (well, a little more than that) | 14:55 |
| kanzure | Lifespan-on-a-Chip: microfluidic chambers for performing lifelong observation of C. elegans http://www.youtube.com/watch?v=Bf26CSnVO94 | 14:58 |
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| kanzure | heh | 15:05 |
| kanzure | http://phdchallenge.org/call-for-participation | 15:05 |
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| cluckj | ahahahahhahahahahaahhahaha | 15:32 |
| cluckj | well I am looking to publish that paper..... | 15:33 |
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| kanzure | cancer-resistant mouse studies: http://www2.wfubmc.edu/tumorbio/srmouse/index.htm | 18:12 |
| kanzure | something in neutrophils | 18:12 |
| kanzure | the transferring is really weird | 18:16 |
| kanzure | http://www2.wfubmc.edu/tumorbio/srmouse/summary.htm | 18:16 |
| kanzure | http://www.wfubmc.edu/tumorbio/srmouse/publications.htm | 18:16 |
| kanzure | "Does cancer reach a detectable size because these controls have failed? If so, could such controls be identified, and enhanced in patients to provide new therapies?" | 18:18 |
| kanzure | "An important initial question in studying these mice was whether the resistance to cancer only worked against this unusual tumor type (S180 sarcoma), or would work against other types of cancer. Using several different mouse cancer types, such as leukemia, lymphoma, liver cancer, and lung cancer, it was shown that the SR/CR mouse was resistant to all of them. " | 18:21 |
| kanzure | http://www2.wfubmc.edu/tumorbio/srmouse/part1.htm | 18:21 |
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| kanzure | "In some cases, this "spontaneous regression" of cancer (Figure 3) was quite dramatic -- a very large tumor mass disappeared overnight." | 18:23 |
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| kanzure | "adoptive transfer" | 18:27 |
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| kanzure | does anyone have access to this? http://www.newscientist.com/article/mg19526224.800-cancerresistant-people-lend-out-their-killer-cells.html | 18:37 |
| kanzure | so they were doing that work back in 2003 | 18:48 |
| kanzure | i'm sort of amazed that they still haven't been able to track down the responsible gene | 18:48 |
| kanzure | it's not that hard.. | 18:48 |
| kanzure | especially since the original strain was practically genetically identical | 18:49 |
| kanzure | you get like 30 spots of interest or something | 18:49 |
| kanzure | someone should put up the money to just get 'em sequenced (but failing this, blots and so on surely don't take 7+ years) | 18:50 |
| kanzure | am i missing something | 18:50 |
| kanzure | cluckj: you know, it wouldn't be too hard to sneak in that phrase into the 'materials' section on a molecular biology paper for some fairly standard experiment but applied to a different organism, or something | 18:51 |
| kanzure | the molbio people ignore that stuff all the time | 18:51 |
| kanzure | Transferable anticancer innate immunity in spontaneous regression/complete resistance mice http://www2.wfubmc.edu/NR/rdonlyres/DFCA7212-A0AC-431F-9622-FBA5C19ED18D/0/pnas5806.pdf | 18:51 |
| kanzure | Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice http://www2.wfubmc.edu/NR/rdonlyres/3ABE12F6-0EDE-4600-8C68-25E85F245244/0/pnas52703.pdf | 18:52 |
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| kanzure | well, jokes on me | 20:07 |
| kanzure | http://www.pr.com/press-release/201382 | 20:07 |
| kanzure | it was john schloendorn / livly.org | 20:07 |
| kanzure | but why in the fuck was he asking for $100k to sequence a genome in 2009? | 20:08 |
| QuantumG | so kanzure, has the idea of 3d printing of synthetic cells (cells made by a synthetic biology process) appeared in print? | 20:09 |
| kanzure | yeah | 20:09 |
| kanzure | "organ printers", cell printers, ... | 20:09 |
| QuantumG | or are people who think about synthetic biology of multicellular organisms still thinking about making organisms that go through gestation? | 20:09 |
| kanzure | nah, organ printing and cellular printing is a craze too | 20:09 |
| QuantumG | sure, but they're not synthetic biology. | 20:09 |
| QuantumG | have the two fields been linked in print yet? | 20:10 |
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| kanzure | what do you mean it's not synthetic biology? | 20:10 |
| kanzure | is it because they don't have drew endy plastering his name all over it? | 20:11 |
| QuantumG | well, I define synthetic biology as forward engineering of biology... and I'm just curious if there are people out there who are saying don't bother trying to forward engineer a gestation process, cause we gotz 3d printers | 20:11 |
| kanzure | i see | 20:12 |
| kanzure | i don't think anyone in synthetic biology has been focusing on engineering gestation really | 20:12 |
| kanzure | so that might be a moot point? | 20:12 |
| QuantumG | I imagine that will be a grand challenge | 20:13 |
| QuantumG | assuming anyone considers it worthwhile and doesn't just fall back on cribbing from nature | 20:13 |
| kanzure | i'm really upset about the livly.org / cancer-resistant mouse thing | 20:29 |
| kanzure | first of all, livly.org is not biocurious.org (as is claimed in that PR release) | 20:29 |
| kanzure | second, $100k to sequence the mouse? in 2009? | 20:29 |
| kanzure | and third, taking 7 years and they still haven't figured out even /which/ chromosome the mutation is on? wtf | 20:29 |
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| QuantumG | this is why competitions are awesome | 20:31 |
| kanzure | okay, sure, but this is john schloendorn | 20:32 |
| kanzure | he's supposed to be defeating aging with diybio in eri's garage or something | 20:32 |
| kanzure | this just looks awful from my point of view | 20:32 |
| genehacker | why's organ printing a craze? | 20:33 |
| kanzure | huh? i mean people are excited about it | 20:34 |
| QuantumG | and that multiple people are working on it | 20:34 |
| genehacker | we can make organs that nature can't probably | 20:34 |
| genehacker | oh wait | 20:34 |
| genehacker | nature doesn't use conventional manufacturing | 20:34 |
| QuantumG | sure | 20:34 |
| kanzure | btw, one of the current challenges with the organ printers (like organovo) is the tubing/pumping and chemical maintenance for the organ | 20:34 |
| kanzure | great, you have an organ! now keep it alive and working :P | 20:34 |
| kanzure | perfusion chambers? | 20:35 |
| kanzure | what are those things called anyway | 20:35 |
| QuantumG | the fact that they're using natural cells (or even modified natural cells) is somewhat limiting | 20:35 |
| kanzure | i wonder why john isn't in here | 20:35 |
| genehacker | well you don't need to keep it alive forever | 20:35 |
| kanzure | anyway someone wanted to sell perfusion chambers with me :P for organovo clients | 20:35 |
| genehacker | once you finish building it you can remove the support and pump blood into | 20:35 |
| kanzure | lots of weird networking problems ot solve, like if you have 10 tanks on a network | 20:35 |
| kanzure | and then you want to make sure downstream/upstream regulation of chemicals is synched | 20:35 |
| genehacker | so keeping it alive is a problem? | 20:36 |
| kanzure | ultimately it was a scheme proposed to me for doing brain-in-a-jar for a multibillionaire who didn't want to die or do cryonics | 20:36 |
| genehacker | we don't have artificial blood? | 20:36 |
| kanzure | sure we do | 20:36 |
| QuantumG | once organs are being printed regularly, and every organ in a mammal can be printed, I think an interesting grand challenge would: print a whole mammal. | 20:36 |
| kanzure | but there's no standard for hooking up artificial organs in some perfusion pumped system | 20:36 |
| genehacker | oh you were talking about that other thing | 20:36 |
| genehacker | whoa | 20:36 |
| QuantumG | would be* | 20:36 |
| genehacker | really? | 20:36 |
| genehacker | he was serious about that? | 20:37 |
| kanzure | .. yes. | 20:37 |
| genehacker | there has been some success with that | 20:37 |
| genehacker | for monkeys | 20:37 |
| kanzure | you mean whole body transplants? | 20:37 |
| genehacker | just the head | 20:37 |
| genehacker | alive | 20:37 |
| kanzure | yes, but it wasn't a head in a jar | 20:37 |
| kanzure | well tbh it probably involved a jar during the surgery | 20:38 |
| kanzure | so that it doesn't role away | 20:38 |
| kanzure | STOP THAT MONKEYHEAD | 20:38 |
| genehacker | they only lasted for a couple days though | 20:38 |
| genehacker | ran out of resources or something | 20:38 |
| kanzure | iirc the monkeys died | 20:38 |
| genehacker | I guess one could keep a multibillionare going | 20:38 |
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| genehacker | yikes someone has a working head transplant method | 20:40 |
| kanzure | dr. white? or the russians | 20:41 |
| genehacker | the russians | 20:42 |
| genehacker | fuck someones done the head in the jar thing in the 1880s | 20:42 |
| kanzure | 'we transplant head, yes?' | 20:42 |
| genehacker | and had some success too | 20:42 |
| genehacker | http://en.wikipedia.org/wiki/Isolated_brain | 20:43 |
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| kanzure | open science summit 2010 http://p2pfoundation.ning.com/profiles/blogs/invitation-for-the-open | 21:33 |
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| kanzure | http://bootstrappingmypersonalsingularity.posterous.com/ok-not-too-dumb-without-googlenet | 21:55 |
| kanzure | http://www.oscon.com/oscon2010/public/schedule/topic/Health/?cmp=il-radar-conf-oscon10-mattman | 21:55 |
| kanzure | ouch, joseph jackson got scooped | 21:55 |
| kanzure | jrayhawk: you should go to that | 21:56 |
| kanzure | why is melanie swan speaking there? | 21:59 |
| kanzure | blah i don't understand how these people get around so quickly | 21:59 |
| kanzure | am i missing some black magic trick? | 21:59 |
| AJollyLife | teleportation, clearly. | 22:00 |
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| kanzure | no, i mean, am i not whoring myself out enough? | 22:01 |
| QuantumG | its who you know | 22:02 |
| QuantumG | and yes, how willing you are to say "hey Bob, you've got this event coming up have you arranged a speaker yet? Can I get in on that gig?" | 22:02 |
| kanzure | a lot of people? http://designfiles.org/~bryan/meetlog/meetlog.txt | 22:02 |
| kanzure | i see. | 22:02 |
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| jrayhawk | the medical industry is like africa: no matter how good the work you do to improve the situation is, they'll still find some way to make it worse | 22:23 |
| kanzure | wtf does that have to do with africa | 22:26 |
| kanzure | hah | 22:26 |
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| kanzure | venture funding for personalized medicine http://www.haaretz.com/magazine/week-s-end/taking-it-personally-1.2969632 | 22:47 |
| kanzure | "Even though, since 1971 - when [U.S. president] Richard Nixon declared the war on cancer as a national goal - more than $105 billion has been invested in research, hardly any progress has been achieved." | 22:47 |
| kanzure | "gentris" | 22:48 |
| kanzure | http://sciencelife.uchospitals.edu/2010/06/18/linkage-618-the-personalized-medicine-highway-more-world-cup/ | 22:48 |
| kanzure | http://glasscityjungle.com/wordpress/2010/06/ohio-state-university-projectone-ground-breaking-held-today-6000-indirect-jobs/ | 22:49 |
| kanzure | http://rupindhamankar.wordpress.com/2010/06/18/personalized-medicine-what-is-it/ | 22:49 |
| kanzure | http://xtrakin.wordpress.com/2010/06/19/direct-primary-care-direct-care-and-concierge-medicine-defined/ | 22:49 |
| kanzure | http://www.scientistsolutions.com/t14768-advances+in+pediatric+personalized+medicine.html | 22:50 |
| kanzure | http://sciencelife.uchospitals.edu/2010/06/18/linkage-618-the-personalized-medicine-highway-more-world-cup/ | 22:50 |
| kanzure | er, irssi error :/ | 22:50 |
| QuantumG | cancer = understanding-of-the-genome-complete | 22:50 |
| QuantumG | I wonder if that widespread opinion is correct | 22:50 |
| kanzure | uh, that's a widespread opinion? | 22:53 |
| kanzure | i can't figure out why anyone would use this | 22:53 |
| kanzure | http://developers.facebook.com/docs/reference/plugins/like | 22:53 |
| QuantumG | isn't it? | 22:53 |
| kanzure | it doesn't let you capture the data on your own | 22:54 |
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| kanzure | god you know something's wrong when you search for stuff on facebook development documentation, and you get all this "blackhat seo" shit | 23:50 |
| kanzure | http://www.blackhatworld.com/blackhat-seo/facebook/182290-comment-box-fbml.html | 23:50 |
| * kanzure is trying to figure out what fbjs_event is from | 23:50 | |
| * genehacker ponders making bacteria capable of producing snake venom | 23:59 | |
| genehacker | or at least the antivenom | 23:59 |
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