--- Day changed Sat Jul 03 2010 | ||
AJollyLife | ive considered couch surfing, but never got around to it | 00:18 |
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JayDugger | Good morning, streety. | 01:11 |
streety | morning | 01:11 |
fenn | good morning, eulenspiegel | 01:12 |
fenn | i finally figured out what this was http://www.flickr.com/photos/23882161@N03/galleries/72157622598778599 | 01:12 |
fenn | there's an awful photoshop of it that got stuck in my head for a few days | 01:13 |
fenn | er, last photo | 01:13 |
streety | without the other photos I can imagine it would be difficult to recognise | 01:14 |
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brunsgenus | Well, I was wanting to know what you all thought about taking the DNA of Turritopsis dohrnii and implementing it on a person using viral treatment? | 06:41 |
brunsgenus | ^ anyone have any comments? | 06:41 |
kanzure | hm | 06:42 |
brunsgenus | i have other idea on how | 06:42 |
brunsgenus | but i wanna know someones opinion first | 06:43 |
kanzure | streety: yeah i never really knew why they bothered with the forum | 06:43 |
brunsgenus | i know viral treatment is like russian roulette | 06:43 |
kanzure | brunsgenus: no, viral gene therapy has improved | 06:43 |
kanzure | http://designfiles.org/papers/gene-therapy/ | 06:43 |
kanzure | ^ read up on it | 06:43 |
brunsgenus | orly? | 06:43 |
brunsgenus | last i heard some kids red blood cells exploded lol | 06:43 |
brunsgenus | well that was the first attempt at it but yeah | 06:43 |
brunsgenus | kanzure: what do you think of my idea, though | 06:44 |
kanzure | it seems underdeveloped.. why would you take dna from 'turritopsis dohrnii'? | 06:45 |
brunsgenus | whenever that jellyfish is about to starve to death it breaks itself back down equivalent to what we were in the womb and makes more jellyfish | 06:48 |
brunsgenus | kanzure: did you not know that jellyfish existed? | 06:49 |
kanzure | mighty big leap of assumptions you just made there | 06:51 |
brunsgenus | yeah i know | 06:51 |
kanzure | how'd you get from a jellyfish gerontology to wondering if i knew that jellyfishes existed? | 06:51 |
brunsgenus | I dunno, you said the name in quotes | 06:51 |
brunsgenus | Also I have ADD | 06:52 |
brunsgenus | lol | 06:52 |
brunsgenus | Sorry if I offended | 06:53 |
brunsgenus | But what do you think of my idea? | 06:53 |
kanzure | it still seems underdeveloped | 06:54 |
kanzure | what genes are you going to take out of the dna? | 06:54 |
kanzure | and what are you going to do with them | 06:54 |
brunsgenus | here we go, this is what i was wanting to look into | 06:54 |
brunsgenus | well the reason why I even said use it in viral treatment because, from what I have learned that is almost the only to make such a drastic change on an organism that is already developed and alive | 06:55 |
brunsgenus | also I havent found out what the genes were | 06:55 |
kanzure | 'make such a drastic change' yes but what is the drastic change that you want to implement? | 06:56 |
brunsgenus | another idea is in the 8 celled stage of development taking out the other 7 and putting this DNA in there and then activating it when the fetus is developing | 06:56 |
kanzure | talking about the jellyfish end-of-life-cycle is pretty vague.. can you be more specific about what you want to do | 06:56 |
brunsgenus | oh | 06:56 |
brunsgenus | sorry I forgot to mention it all | 06:57 |
brunsgenus | well obviously you would have to do some modifying but basically when you hit x aging point you go back to x point in life and yes i know that makes even more questions but i am talking about more so skeletal tissue etc. not neurons | 06:58 |
brunsgenus | neurons you have to do something else | 06:58 |
kanzure | "you go back to x point in life" what do you mean by this? time travel?? | 06:59 |
brunsgenus | thats still not all but i wont remember till you ask | 06:59 |
brunsgenus | x point in life meaning development | 06:59 |
brunsgenus | Like eh say go back to the point after puberty | 06:59 |
brunsgenus | i mean that would be a good genetic marker | 06:59 |
kanzure | my guess is that you don't know what a genetic marker is :P | 07:00 |
brunsgenus | nope | 07:00 |
brunsgenus | :D | 07:00 |
kanzure | so, what do you know, then? | 07:00 |
brunsgenus | i know that i like reading and im majoring in biology and micro biology in college, then i have to do stuff after that but as of right now im an undergrad with no biology classes | 07:00 |
kanzure | have you ever had a biology class | 07:01 |
brunsgenus | yes? | 07:01 |
kanzure | okay, just had to ask | 07:01 |
brunsgenus | :( | 07:01 |
brunsgenus | i sound that stupid huh? | 07:01 |
kanzure | well, i like the idea of using something from the jellyfish | 07:01 |
kanzure | do you have any papers on those genes? or the name of the genes, etc. | 07:02 |
brunsgenus | no, this is something i was doing like when i was 13 | 07:02 |
brunsgenus | i just came back to it recently | 07:02 |
brunsgenus | i have been messing around with computers | 07:02 |
brunsgenus | im bored with those now so i wanna do genetics again | 07:02 |
brunsgenus | I might be able to gather material if you can specify what exactly you want | 07:02 |
brunsgenus | otherwise I am going to gather a bunch of interesting-yet-useless information | 07:03 |
kanzure | http://scholar.google.com/ go forth and search :) | 07:03 |
kanzure | oh this is "the immortal jellyfish" stuff. righto | 07:03 |
brunsgenus | alright thanks | 07:03 |
kanzure | Induction of reverse development in two marine Hydrozoans http://www.ijdb.ehu.es/web/pdfdownload.php?doi=062152js | 07:04 |
kanzure | yeah if you can find the piraino paper that will probably be revealing. | 07:05 |
brunsgenus | what do you mean | 07:06 |
brunsgenus | revealing in what way | 07:06 |
kanzure | informative? | 07:07 |
brunsgenus | it was a joke :/ | 07:07 |
brunsgenus | im bad at those | 07:07 |
brunsgenus | they make me laugh | 07:07 |
kanzure | Piraino, S. et al. 1996. Reversing the life cycle: medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa). Biological Bulletin 190: 302-312. | 07:07 |
brunsgenus | http://www.sciencepub.net/nature/ns0802/03_1279_hongbao_turritopsis_ns0802_15_20.pdf | 07:09 |
brunsgenus | here | 07:09 |
brunsgenus | I think this one is a different breed but does the same thing | 07:10 |
brunsgenus | just for a different reason | 07:10 |
brunsgenus | yeah this one is after puberty reverts back | 07:12 |
brunsgenus | i got it confused with erg i forgot the name, its big and long too | 07:12 |
kanzure | typo: 'organsism' on the first page | 07:12 |
brunsgenus | Hey maybe he didn't have a good teacher in school. | 07:12 |
brunsgenus | lol | 07:13 |
kanzure | or a spellchecker? was this a published article | 07:13 |
brunsgenus | sciencepub.net | 07:14 |
brunsgenus | lol | 07:14 |
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brunsgenus | But this is what I am hoping to pursue after college, maybe sooner if I can get a group of people interested in it with me | 07:16 |
JayDugger | Good morning. No photoshopped lotus blossoms or Central European tricksters this morning? | 07:16 |
brunsgenus | hold on ill give you one | 07:16 |
brunsgenus | http://www.pxleyes.com/images/contests/flower%20heads/fullsize/flower%20heads_4b1ef999a56e9.jpg | 07:17 |
brunsgenus | there you go | 07:17 |
brunsgenus | jaydugger ^ | 07:17 |
brunsgenus | kanzure; what do you think? | 07:18 |
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brunsgenus | kanzure? | 07:23 |
kanzure | brunsgenus: so far it seems like this jellyfish is significantly understudied | 07:25 |
kanzure | you'll probably have to do a few whole genome sequencing studies or single nucleotide polymorphism (SNP) analyses to figure out how it's different from other jellyfish | 07:25 |
kanzure | and then study molecular biology for a bit, etc. | 07:25 |
brunsgenus | :( | 07:27 |
kanzure | what's wrong with that? | 07:29 |
brunsgenus | I don't have the resources to do genome sequencing studies | 07:30 |
brunsgenus | I am just a small town girl | 07:30 |
brunsgenus | living in a lonely world | 07:30 |
brunsgenus | lol | 07:31 |
kanzure | what sort of resources do you think it takes? | 07:31 |
kanzure | i mean, next year it's going to cost a hundred bucks | 07:31 |
brunsgenus | It takes money | 07:32 |
brunsgenus | I just spent 500 | 07:32 |
brunsgenus | and have no job | 07:32 |
brunsgenus | lol | 07:32 |
brunsgenus | ugh i am going to have to do freaking computer repairs again lol | 07:32 |
kanzure | why is that funny? | 07:35 |
brunsgenus | the irony is funny | 07:35 |
brunsgenus | I just fixed up an old computer and sold it for 500, then blew that away in a week | 07:35 |
JayDugger | Are the jellyfish about to go extinct? Are you? If not, then cultivate patience and work on them as fast you can. | 07:35 |
kanzure | "about to go extinct" wouldn't make sense- he's talking about the 'immortal' jellyfish | 07:36 |
brunsgenus | jaydugger | 07:36 |
brunsgenus | I have ADD | 07:36 |
JayDugger | Unless you're in a race. | 07:36 |
brunsgenus | lol | 07:36 |
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kanzure | brunsgenus: can you stop saying "I have ADD"? so does everyone else here. | 07:36 |
brunsgenus | ADD kids are impatient | 07:36 |
JayDugger | I don't. | 07:37 |
brunsgenus | ^ | 07:37 |
brunsgenus | kanzure you are wrong | 07:37 |
brunsgenus | face. | 07:37 |
cluckj | hah | 07:37 |
cluckj | you can learn to be patient | 07:37 |
brunsgenus | I know | 07:37 |
kanzure | cluckj: not really | 07:37 |
brunsgenus | :( | 07:37 |
kanzure | brunsgenus: you should just get high on adderall (like i do) | 07:37 |
cluckj | I did it :P | 07:37 |
brunsgenus | kanzure i have been taking medication since the 2nd grade | 07:37 |
JayDugger | But my girlfriend does, and that's provided plenty of opportunities for patience. | 07:37 |
kanzure | in my case, it's ADHD | 07:37 |
brunsgenus | protip: It doesn't work anymore | 07:37 |
kanzure | brunsgenus: check if they changed manufacturers on you.. yeah. | 07:38 |
cluckj | I started and quit taking meds for my ADD in high school | 07:38 |
JayDugger | nice image of a lotus, BTW. | 07:38 |
brunsgenus | kanzure: no, just to spite you | 07:38 |
brunsgenus | jaydugger thank you, I thought you would like it | 07:38 |
brunsgenus | haha | 07:38 |
cluckj | I decided that I'd rather fight it with behavior modification than drugs | 07:38 |
kanzure | "fight it"? why would you want to do that | 07:39 |
kanzure | wouldn't you want to enhance it? | 07:39 |
brunsgenus | I have decided that I am not going to participate in discussing ADD | 07:39 |
* brunsgenus sits quietly | 07:39 | |
JayDugger | What's the argument for that? | 07:39 |
JayDugger | I've never heard one; I am curious. | 07:39 |
cluckj | kanzure because I like being able to focus sometimes | 07:40 |
kanzure | it's a common misconception that you can't focus.. just only on the things you actually care about. | 07:40 |
cluckj | yep | 07:40 |
cluckj | hyperfocusing | 07:40 |
brunsgenus | kanzure is correct; its why i havent slept in 3 days | 07:41 |
brunsgenus | shit sux | 07:41 |
cluckj | haha | 07:41 |
brunsgenus | lol | 07:41 |
cluckj | yeah exactly | 07:41 |
brunsgenus | and yes, I have gotten to the point of hallucination | 07:41 |
brunsgenus | and im all sweaty which means I should shower soon | 07:42 |
cluckj | kanzure you're doing it with medication, I do it with cigarettes, coffee and behavioral modification | 07:42 |
brunsgenus | cluckj | 07:43 |
brunsgenus | thats funny that you mention it | 07:43 |
brunsgenus | because prior to me drinking coffee, using tobacco or trying to control myself I took medication | 07:43 |
cluckj | haha | 07:43 |
brunsgenus | but I have got to say, I took medication the other day and damn it helps a lot more obviously | 07:44 |
brunsgenus | So where would I go for genome sequencing? | 07:44 |
cluckj | it's not exactly trying to control myself, it's just changing what I do when I need to focus on something | 07:44 |
brunsgenus | I zone out if i dont want to do it, i learned to just do it but i wont be all there when im doing it | 07:45 |
cluckj | I do whatever I don't want to be doing in a way that makes me want to do it :) | 07:45 |
brunsgenus | oh so like, if you wanted to dip but didnt because of it making your teeth gross you put it between your toes | 07:46 |
brunsgenus | because that works too | 07:46 |
brunsgenus | yah know | 07:46 |
cluckj | lol | 07:47 |
JayDugger | Time to run errands; goodbye, everyone. | 07:47 |
brunsgenus | bi | 07:47 |
cluckj | does it? | 07:47 |
cluckj | cya | 07:47 |
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brunsgenus | you can do it under the armpit too | 07:47 |
brunsgenus | anywhere with soft skin, really | 07:47 |
cluckj | cool | 07:47 |
brunsgenus | so where would I go for genome sequencing? | 07:47 |
cluckj | dipping is really gross though | 07:47 |
brunsgenus | I mean I just plop the jellyfish down and tell them to have at it? | 07:47 |
cluckj | what kind of sequencing? | 07:47 |
brunsgenus | cluckj you are really gross | 07:47 |
kanzure | you could buy your own machines, build your own, pay money, or get someone at a university or company to do it for you | 07:47 |
cluckj | probably, yeah | 07:48 |
cluckj | but I clean up nice | 07:48 |
brunsgenus | we will see about that | 07:48 |
brunsgenus | http://www.facebook.com/joncluck?ref=ts | 07:48 |
brunsgenus | cluckj ^ | 07:48 |
kanzure | haha you actually used that photo | 07:49 |
brunsgenus | lol | 07:49 |
cluckj | yep | 07:49 |
cluckj | hell yeah, it's a great photo | 07:49 |
brunsgenus | it looks matrix-e | 07:49 |
brunsgenus | anyways, how much would a machine cost? | 07:49 |
kanzure | $300 on ebay | 07:49 |
brunsgenus | orly? | 07:49 |
kanzure | but those are older models | 07:49 |
brunsgenus | so not that much | 07:49 |
brunsgenus | oh | 07:49 |
kanzure | the new shit costs $25k+ | 07:49 |
brunsgenus | oh...uhm | 07:50 |
cluckj | I put "haters gonna hate" as the caption because it reminds me of this: http://livingelpaso.files.wordpress.com/2010/03/haters.jpg | 07:50 |
brunsgenus | Anyone wanna lend me 25k+? | 07:50 |
kanzure | brunsgenus: i might be able to lend that | 07:50 |
kanzure | but what are you going to do with it? | 07:50 |
brunsgenus | cluckj it couldn't be becuase you like channing? | 07:50 |
brunsgenus | kanzure persue what we were talking about earlier | 07:50 |
cluckj | ew | 07:50 |
cluckj | don't insult me | 07:50 |
cluckj | I just love internet memes | 07:51 |
brunsgenus | Hey hey...I own a chan | 07:51 |
brunsgenus | well you can thank chans for internet memes | 07:51 |
brunsgenus | Do you know what the first internet meme was? | 07:51 |
cluckj | nope | 07:51 |
brunsgenus | http://media.photobucket.com/image/dancing%20baby/shanta824/DANCING_BABY.gif | 07:51 |
brunsgenus | this ^ | 07:51 |
cluckj | awesome | 07:52 |
brunsgenus | kanzure, tbh I am wanting to get a group of people to work on this specifically | 07:52 |
kanzure | that is one hell of an ugly guy in that .gif | 07:52 |
brunsgenus | I don't know who to get into contact with though | 07:52 |
cluckj | speaking of me being gross, brb | 07:52 |
cluckj | I want some diy bio yogurt for breakfast | 07:53 |
kanzure | so why do you think that this jellyfish is a better pursuit of resources than, say, stem cell therapies | 07:53 |
brunsgenus | because it is already there, or as close as we can get to it. also there are less legal issues to work around than stem cells. anything involving that word gets media attention, the bad press, then they get shut down because of some lame ass politician | 07:54 |
brunsgenus | the jellyfish has it out there already and since everything is so closely related on earth already i thought it would be the path of least resistance | 07:54 |
kanzure | "it is already there" well not really.. the genetics and developmental biology between jellyfish and humans are ridiculosuly complex | 07:55 |
kanzure | it's certainly worth studying, yes | 07:55 |
kanzure | and there might be something interesting in the genes | 07:55 |
brunsgenus | Well yeah, like i said before it would need modification but it is an untapped potential resource | 07:55 |
kanzure | but it's definitely not a turn-key thing. | 07:55 |
brunsgenus | How old are you? | 07:56 |
kanzure | 20 | 07:56 |
kanzure | you? | 07:56 |
brunsgenus | I was about to say, this certainly doesn't look like a 20 year old in the picture | 07:56 |
brunsgenus | lol | 07:56 |
brunsgenus | I am 19 | 07:56 |
cluckj | mmm | 07:57 |
kanzure | brunsgenus: facebook sucks. just use my website. http://heybryan.org/ | 07:57 |
kanzure | oh wait. i turned off my server. | 07:57 |
kanzure | sucks for you | 07:57 |
brunsgenus | 000chan.org | 07:57 |
brunsgenus | ^ my site | 07:57 |
brunsgenus | shit sux | 07:57 |
kanzure | brunsgenus: you mean gurochan. | 07:57 |
brunsgenus | guro guro | 07:57 |
kanzure | would you like some lotion for that burn? | 07:57 |
brunsgenus | derp | 07:58 |
brunsgenus | The site went crazy last night after I tried to do some modifications so I had to wipe my most popular board | 07:58 |
brunsgenus | How much would it cost to get a university or something to do the genome sequencing? | 07:59 |
kanzure | the costs are dropping quickly | 07:59 |
kanzure | ten years ago it was about a million dollars | 08:00 |
kanzure | 5 years ago about $300k | 08:00 |
kanzure | 3 years ago about $100k | 08:00 |
kanzure | this year it's about $10k | 08:00 |
brunsgenus | I am not going to have to wait years am i... | 08:00 |
brunsgenus | oh damn | 08:00 |
kanzure | and a few companies are trying to get it under $100 | 08:00 |
brunsgenus | I am not good with that, I will have to try and get it for cheaper | 08:00 |
brunsgenus | yeah like IBM | 08:00 |
kanzure | what about IBM? huh? | 08:00 |
brunsgenus | they claim they will be able to knock it down to 58k | 08:01 |
brunsgenus | They are joining forces with uhm | 08:01 |
kanzure | aquaman? | 08:01 |
brunsgenus | lol | 08:01 |
brunsgenus | some company so that it can be knocked down cheaper | 08:01 |
brunsgenus | obviously what is in it for them is the computer software/machine | 08:01 |
brunsgenus | thats where they make their chunk of change | 08:01 |
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brunsgenus | building one myself might be the easiest and fastest solution | 08:04 |
brunsgenus | kanzure: do you know of anyone who would want to research this with me? | 08:05 |
kanzure | http://bits.blogs.nytimes.com/2010/03/20/would-you-pay-20-for-access-to-a-breast-cancer-cure/ | 08:05 |
kanzure | brunsgenus: us in here :) | 08:05 |
kanzure | and others. (brb) | 08:05 |
brunsgenus | orly? | 08:06 |
brunsgenus | kanzure: so we start at genome sequencing i guess | 08:08 |
brunsgenus | I can set up an account for us to dump money into/accept donations | 08:08 |
brunsgenus | to get the ball rolling | 08:08 |
brunsgenus | Argentina v Germany game | 08:10 |
brunsgenus | no sound | 08:10 |
brunsgenus | http://www.justin.tv/llion1 | 08:10 |
brunsgenus | live stream | 08:10 |
brunsgenus | have fun | 08:10 |
brunsgenus | if that doesnt work for you guys I have another link | 08:10 |
brunsgenus | Anyone else watching? | 08:14 |
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brunsgenus | i love corn dogs | 08:34 |
brunsgenus | anyways.. kanzure am I right? | 08:34 |
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brunsgenus | man it is pretty quiet in here... | 08:39 |
AJollyLife | brunsgenus: woo for add! :) | 08:42 |
brunsgenus | :D | 08:43 |
AJollyLife | i just woke up :) | 08:44 |
brunsgenus | orly? | 08:44 |
brunsgenus | I havent slept for 3 days | 08:44 |
AJollyLife | yeah, i tend to go to bed late, and wake up late | 08:44 |
AJollyLife | modafinil? | 08:44 |
AJollyLife | or just excited about stuff? | 08:44 |
brunsgenus | I don't know | 08:44 |
brunsgenus | I just didn't feel like sleeping | 08:44 |
AJollyLife | heh. its funny, but when im on add meds, i sleep more | 08:44 |
brunsgenus | I have to remember to eat/sleep | 08:44 |
brunsgenus | because i dont get hunger pains | 08:45 |
AJollyLife | cause otherwise there is too much to research/learn/do and sleep/eating is boring | 08:45 |
brunsgenus | and i dont feel tired | 08:45 |
AJollyLife | yeah, im mostly the same way | 08:45 |
brunsgenus | i dont take medication | 08:45 |
AJollyLife | been trying to force myself to sleep more though since its good for oyu | 08:45 |
brunsgenus | i havent for years | 08:45 |
AJollyLife | medication certainly has its downsides | 08:45 |
AJollyLife | i took it when i was in school, but dont these days | 08:45 |
brunsgenus | yeah i try to force myself to sleep but it doesnt work out lol | 08:45 |
brunsgenus | if i drink heavily i can go to sleep so well | 08:45 |
AJollyLife | yeah, i usually just keep doing stuff till i'm exhausted | 08:45 |
brunsgenus | but I have TMJ | 08:45 |
brunsgenus | and so waking up sucks ass | 08:46 |
brunsgenus | and i wake up from my teeth scraping together | 08:46 |
brunsgenus | it suckkks | 08:46 |
AJollyLife | tmj? | 08:46 |
brunsgenus | or cracking sounds | 08:46 |
brunsgenus | yeah | 08:46 |
brunsgenus | hold on | 08:46 |
brunsgenus | http://en.wikipedia.org/wiki/Temporomandibular_joint_disorder | 08:46 |
AJollyLife | cluckj: looking at that photo, it would have worked better if i had you take off your namebadge :( | 08:47 |
AJollyLife | thanks :) | 08:47 |
brunsgenus | I am going to show you all my fb | 08:47 |
brunsgenus | DONT LAUGH | 08:47 |
brunsgenus | ://www.facebook.com/Jrrdlkdl | 08:47 |
brunsgenus | I am eating a paper icecream cone in that one | 08:48 |
AJollyLife | why? | 08:49 |
brunsgenus | because this girl and i were at chick file | 08:50 |
brunsgenus | filet | 08:50 |
brunsgenus | w.e | 08:50 |
brunsgenus | and she kept telling me to get icecream because she didnt want to be the only one eating one | 08:50 |
brunsgenus | and i told her icecream was stupid | 08:50 |
brunsgenus | and we argued | 08:50 |
brunsgenus | and i caved in and made icecream | 08:50 |
brunsgenus | and at it, it wasn't very good though | 08:50 |
brunsgenus | ate* | 08:50 |
brunsgenus | mostly because it was paper | 08:51 |
brunsgenus | oh man...i need to stop talking | 08:53 |
AJollyLife | lol | 08:54 |
brunsgenus | trufax, though | 08:54 |
brunsgenus | so did you read what I was talking about earlier? | 08:55 |
AJollyLife | a bit | 08:55 |
brunsgenus | did it sound stupid? | 08:55 |
cluckj | AJollyLife haha | 08:56 |
brunsgenus | :( | 08:56 |
AJollyLife | meh, im not a bioguy, im a computer guy | 08:56 |
brunsgenus | im kinda of a computer guy | 08:57 |
brunsgenus | sept i suck ass at programming | 08:57 |
brunsgenus | so why is everyone quiet? | 08:58 |
cluckj | I'm getting ready to go out | 08:59 |
brunsgenus | im not | 08:59 |
brunsgenus | i wanted to continue talking to kanzure | 09:00 |
brunsgenus | >:| he left | 09:00 |
AJollyLife | meh, its a satruday, and this isnt a huge traffic channel | 09:01 |
cluckj | he's a busy dude | 09:01 |
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brunsgenus | I wanna go shove a firecracker up a squirrels ass but there are none of them left. | 09:04 |
bdesk | wat | 09:04 |
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brunsgenus | lol | 09:04 |
AJollyLife | anyone here going to the singularity summit? | 09:08 |
brunsgenus | can i answer if i am not going? | 09:09 |
AJollyLife | sure | 09:09 |
cluckj | I think my friend grant is going to try to go | 09:09 |
brunsgenus | i wanna go :( | 09:09 |
kanzure | the singularity summit looks lame this year | 09:11 |
brunsgenus | i bet obama is going and will get an award | 09:11 |
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kanzure | hi bdesk | 09:14 |
bdesk | kanzure: hey, how was scipy2010? | 09:14 |
kanzure | it went well :) | 09:14 |
kanzure | i presented on pythonocc | 09:15 |
kanzure | the enthought guys know their shit | 09:15 |
bdesk | so it was well organized? | 09:15 |
brunsgenus | hai | 09:15 |
bdesk | did you see the bioinformatics talks? I think galaxy was there. | 09:15 |
bdesk | brunsgenus: the eschaton is upon us. make your time. | 09:16 |
kanzure | no, i didn't see the bioinformatics talks :( | 09:17 |
bdesk | how many $$$$ of equipment do I need before pythonocc is useful for me? | 09:17 |
brunsgenus | bdesk, eschaton? | 09:18 |
bdesk | brunsgenus: it is the singularity. the end of times as we know them. | 09:18 |
brunsgenus | OH SHI- | 09:19 |
* brunsgenus runs through time in reverse | 09:19 | |
brunsgenus | AHA | 09:19 |
kanzure | bdesk: pythonocc can be installed on a regular laptop.. what are you talking about? | 09:20 |
brunsgenus | why would you want pythonocc? | 09:20 |
bdesk | kanzure: yes I know it is software, but the purpose of CAD is to design irl things, right? | 09:21 |
bdesk | i am not good at irl. | 09:21 |
kanzure | oh are you wondering how to actually build something that you have a CAD file for? | 09:21 |
bdesk | yes i guess. | 09:22 |
kanzure | honestly it depends on what the model is.. some things can be plastic molded, other things are meant to be cut from metals | 09:22 |
kanzure | so let's say it's a plastic part | 09:22 |
kanzure | you could go to protomold.com and get it injection molded, you could go to ponoko or shapeways to get it "printed" | 09:23 |
kanzure | or you could build your own cnc machine or 3d printer or whatever it is that you're trying to do | 09:23 |
bdesk | ok. | 09:23 |
kanzure | build your own / buy your own, depending on your 'evolved' tastes. :P | 09:23 |
bdesk | does reprap use this format? reprap is the only 3d printer i've read about. | 09:23 |
kanzure | solid geometry cad is like source code, and what reprap uses is like a 'compiled binary object file' called STL | 09:24 |
kanzure | so do your design in CAD, then convert the file to STL | 09:24 |
kanzure | CAD -> STL is a very easy conversion. | 09:24 |
kanzure | STL -> CAD is ridiculously hard and you're talking a few grad students and a phd thesis :P | 09:24 |
kanzure | pythonocc is better for doing programmatic CAD design | 09:25 |
kanzure | now if you want to just have a user interface or something, try heekscad | 09:25 |
kanzure | http://heekscad.org/ | 09:25 |
bdesk | so with pythonocc i could write a python program that makes a widget design programmatically and then pythonocc will also do the conversion to STL? | 09:25 |
kanzure | yes | 09:26 |
kanzure | of course, you'll have to call model.to_stl() or something | 09:26 |
bdesk | and then i could print it with reprap if the design is simple enough. | 09:26 |
kanzure | yes :) | 09:26 |
bdesk | and pythonocc and the CAD->STL converter does not need to know anything about reprap. | 09:26 |
kanzure | correct but sometimes you want to go back and regenerate the STL Mesh | 09:27 |
kanzure | *STL mesh | 09:27 |
kanzure | like maybe you want to increase the number of triangles, or something | 09:27 |
brunsgenus | triangles are stupid >:/ | 09:30 |
bdesk | brunsgenus: eternity is longer than you can imagine. what finite comforts would you be willing to sacrifice to join us in this infinite utopia? | 09:30 |
brunsgenus | I have an endless supply of hotpockets.... | 09:30 |
brunsgenus | want those? | 09:31 |
kanzure | bdesk: wtf are you talking about and why are you talking to brunsgenus about it? O_O | 09:32 |
brunsgenus | kanzure is it bad to talk to me> :( | 09:32 |
brunsgenus | You think because I said it, therefore it needs to be discredited? | 09:33 |
brunsgenus | :( | 09:33 |
AJollyLife | xena reruns and hotpockets? | 09:33 |
bdesk | brunsgenus: a true cornucopia awaits. | 09:33 |
brunsgenus | :D | 09:34 |
bdesk | brunsgenus: imagine a post-scarcity society. | 09:34 |
brunsgenus | cheeseburger hotpockets....AS FAR AS THE EYE CAN SEE | 09:34 |
kanzure | brunsgenus: no, i don't think it's bad to talk to you | 09:35 |
kanzure | it just doesn't make sense to me | 09:35 |
brunsgenus | oh | 09:36 |
brunsgenus | my teeth hurt | 09:36 |
brunsgenus | I want a fag | 09:36 |
bdesk | kanzure: you have made irl widgets with pythonocc? | 09:37 |
brunsgenus | lol i have a retainer | 09:40 |
brunsgenus | i just took it out | 09:40 |
brunsgenus | and spit got on my mousepad | 09:40 |
brunsgenus | fuck | 09:43 |
brunsgenus | ugh | 09:43 |
brunsgenus | I just got tricked into going to dinner... | 09:43 |
brunsgenus | dammit....now i have to buy a bday present | 09:44 |
brunsgenus | why is it no one in here is admin or operator or anything? | 09:52 |
kanzure | freenode doesn't want an operator for this channel | 09:56 |
brunsgenus | why | 09:58 |
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bdesk | People will be free to devote themselves to activities that are fun, such as programming, after spending the necessary ten hours a week on required tasks such as legislation, family counseling, robot repair and asteroid prospecting. | 10:10 |
brunsgenus | if you guiz wanna join an irc that is fucking weird (my irc) | 10:14 |
brunsgenus | irc.789chan.org #000chan | 10:14 |
brunsgenus | http://000chan.org/b/src/127817731136.gif | 10:15 |
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kanzure | http://bookhling.wordpress.com/2010/07/03/8bit-tools-of-science/ | 11:05 |
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bdesk | kanzure: what is this "We already have beta versions of synthetic biology CAD program that undergraduates regularly use for their school assignments and private projects" | 11:16 |
kanzure | lots of bullshit | 11:18 |
kanzure | clothocad, for instance.. it's really not CAD | 11:18 |
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bdesk | "Among many possible top-level explanations of Clotho, one of the simplest is the "Clotho Data Structure"-centric view. In this view, biological part data is passed back and forth between Clotho components and to files and databases outside Clotho." | 11:33 |
bdesk | Their project release was 2008 version 1.0 with no updates or source code repo. If their selling point is their translations among data formats, then they will have to release a lot more often than this. | 11:35 |
bdesk | http://clothocad.sourceforge.net/wiki/images/4/42/SynBioToolLandscape.png | 11:40 |
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kanzure | you know, power rangers was pretty terrible when it came out: http://www.youtube.com/watch?v=AkRvn0pXTiw | 13:44 |
kanzure | but this just explained everything to me: http://www.youtube.com/watch?v=sIwmbOoNsX0 | 13:44 |
kanzure | also explains the mecha fixation | 13:44 |
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brunsgenus | hai | 16:17 |
pmetzger | o hai. | 16:21 |
brunsgenus | water u doin | 16:21 |
pmetzger | takin lik a lolcat. | 16:21 |
brunsgenus | wat.... | 16:23 |
brunsgenus | lolcat... | 16:23 |
brunsgenus | ..jesus.... | 16:23 |
pmetzger | loljesus iz diffrent | 16:24 |
brunsgenus | lol u gay | 16:24 |
bdesk | IN MAH YOUNGR AN MOAR VULNERABLE YEERS MAH FATHR GAEV ME SUM ADVICE DAT I'VE BEEN TURNIN OVAR IN MAH MIND EVR SINCE. "WHENEVR U FEELZ LIEK CRITICIZIN ANY WAN," HE TOLD ME, "JUS REMEMBR DAT ALL TEH PEEPS IN DIS WURLD HAVEN'T HAD TEH ADVANTAGEZ DAT U'VE HAD." | 16:24 |
brunsgenus | wat | 16:24 |
bdesk | teh great lolcatsby | 16:25 |
brunsgenus | >lolcat is not cool | 16:25 |
brunsgenus | lol | 16:25 |
brunsgenus | though i do have a lulcat board on my chan | 16:25 |
brunsgenus | it autophilters all the words into catspeak | 16:25 |
brunsgenus | you just have to get the dialect correct | 16:25 |
pmetzger | <brunsgenus> on my 4chan. | 16:25 |
brunsgenus | >on my 000chan | 16:26 |
pmetzger | lolcats are the best thing since sliced plasmids. | 16:27 |
brunsgenus | http://000chan.org/chz/ | 16:27 |
kanzure | you guys are morons. | 16:28 |
kanzure | just saying. | 16:28 |
brunsgenus | :( | 16:28 |
brunsgenus | i has sad | 16:28 |
pmetzger | i can haz restriction enzymez? | 16:28 |
bkero | no restriction enzymez 4 u | 16:29 |
bkero | kanzure: am I morons? | 16:29 |
bdesk | i'm installing R on my other computer. would a moron install R? | 16:29 |
bkero | Yes | 16:29 |
pmetzger | I'm reminded of the line from "A Fish Called Wanda" | 16:30 |
brunsgenus | I am installing ultimate hacking web browser | 16:30 |
brunsgenus | aka internet explorer | 16:30 |
brunsgenus | is that srupid? | 16:30 |
bdesk | pmetzger: that's what i was going for :D | 16:30 |
brunsgenus | stupid* | 16:30 |
bdesk | "yes they would bdesk, they just wouldn't know how to use it!" | 16:30 |
pmetzger | "Apes don't read philosophy" "Yes they do Otto, they just don't understand it." | 16:31 |
pmetzger | R irritates me, but it is a good tool. | 16:31 |
pmetzger | the syntax is irritatingly close to rational, but it is nutty so much of the time... | 16:31 |
pmetzger | if only it sucked more consistently or failed to suck more consistently. | 16:32 |
bdesk | yes it is annoyingly good. | 16:32 |
pmetzger | when I was doing pchem lab, we had this really neat experiment which took ten minutes for the experiment and then weeks for the data crunching | 16:32 |
pmetzger | we took the uv/vis spectrum of gaseous I2 and then figured out all these properties of I2 from it. | 16:33 |
pmetzger | I used a set of scripts (including some R) and got better accuracy than the handbooks have. | 16:33 |
pmetzger | the other people in the class used spreadsheets and laboriously did everything by hand. they never got anywhere near to what I did. | 16:34 |
pmetzger | and I spent less time. | 16:34 |
pmetzger | I even did automated peak finding. | 16:34 |
bdesk | nice | 16:34 |
kanzure | pmetzger: to be fair, the bar was set pretty low.. | 16:34 |
bdesk | wait how do you know your results are better than the handbook? | 16:34 |
kanzure | i've been in situations like that. | 16:34 |
pmetzger | bdesk: because I calculated my error. | 16:34 |
brunsgenus | Aubrey de Grey is a pretty cool guy | 16:35 |
pmetzger | the handbook data was all from the 1960s/1970s, and done on equipment that wasn't nearly so good. | 16:35 |
brunsgenus | I am messaging him on fb lol | 16:35 |
kanzure | brunsgenus: aubrey responds to just about everyone. | 16:35 |
pmetzger | Aubrey is a good chap, yes. | 16:35 |
pmetzger | kanzure: the bar was set low? | 16:35 |
brunsgenus | he is pretty cool | 16:35 |
bdesk | if aubrey de grey spends his time responding to people who are naked in front of their computer eating cheetos and talking like a lolcat then how does he have time to research immortality? | 16:36 |
pmetzger | I've never seen a man who loves his afternoon beer as much as him... | 16:36 |
pmetzger | bdesk: cloning. | 16:36 |
kanzure | bdesk: he doesn't do research | 16:36 |
kanzure | it's primarily the students and labs that do it | 16:36 |
pmetzger | kanzure: he does. he reads a vast amount of literature. | 16:36 |
pmetzger | he just doesn't do any lab work, all theory. | 16:37 |
kanzure | no he doesn't read that much | 16:37 |
kanzure | have you seen his bibliographies? | 16:37 |
kanzure | and compared them to what's actually out there | 16:37 |
kanzure | i mean, yes, he writes papers | 16:37 |
kanzure | but the bulk of his literature is from earlier | 16:37 |
pmetzger | kanzure: well, no matter what obscure paper I bring up with him, he's always read it and remembers the contents better than me. :) | 16:37 |
kanzure | which btw i zipped up here: http://heybryan.org/transhuman/Aubrey.zip | 16:37 |
pmetzger | he does know his stuff very well. | 16:37 |
pmetzger | and he seems to spend a lot of time keeping up with the literature. | 16:38 |
pmetzger | I have my doubts on WILT but I'm not an area specialist. I'm entirely self taught in molbio. | 16:41 |
pmetzger | big lacunae in my background. | 16:41 |
bdesk | wilt chamberlain? | 16:41 |
pmetzger | WILT. | 16:41 |
pmetzger | anti-cancer strategy aubrey has proposed. | 16:41 |
bdesk | ah | 16:42 |
bdesk | i am trained in molbio but i don't know much about transhumanism | 16:43 |
pmetzger | there isn't much to know about transhumanism. | 16:43 |
pmetzger | and aubrey's research isn't into transhumanism, it is into life extension. :) | 16:43 |
bdesk | i see | 16:44 |
pmetzger | transhumanism just means the notion of using technology to go beyond what humans can naturally do (or even to replace the biological substrait) | 16:45 |
AJollyLife | id rather have money spent on antiaging/life extension than transhumanism personally | 16:45 |
pmetzger | substrate | 16:45 |
pmetzger | but it is an idea, it isn't a research topic. | 16:45 |
bdesk | living longer goes beyond what humans can naturally do. | 16:46 |
pmetzger | the research is into things like AI, life extension, augmentation, uploading, etc. | 16:46 |
bdesk | but w/e the distinction is not important to me. | 16:46 |
pmetzger | living indefinitely is certainly not something normal humans can do. | 16:46 |
bdesk | i see that he was the flybase db admin | 16:46 |
pmetzger | at one point. | 16:46 |
pmetzger | day job. | 16:46 |
pmetzger | bbl, going for a bike ride before it gets dark. | 16:47 |
bdesk | kbye | 16:47 |
bdesk | i'd rather have money spent on flybase than antiaging/life extension personally. | 16:49 |
kanzure | "Your Austin Meetup Calendar: 484 Meetups this week! | 16:49 |
kanzure | well that's useless.. | 16:49 |
kanzure | bdesk: there are lots of youtube-aubrey videos | 16:49 |
bdesk | kanzure: maybe you could convince them to all meet in one stadium at the same time. | 16:49 |
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fenn | the first internet meme was "this page is under construction" | 16:52 |
* fenn snickers at the idea of "the first internet meme" | 16:52 | |
fenn | oh, he left | 16:54 |
fenn | (praise be to his noodly appendage) | 16:55 |
kanzure | fenn: did you know that power rangers was japanese? | 16:57 |
kanzure | i'm totally perplexed as to how i could miss that.. | 16:57 |
ybit | that changes everything, japanese power rangers | 17:07 |
bdesk | so is there a list of the projects that people in this channel are involved with? i'm from academia and I want to see if i'm missing anything cool. | 17:11 |
bdesk | i see http://www.acceleratingfuture.com/wiki/Hplusroadmap_wiki | 17:12 |
kanzure | there's no master list, no.. but there's a master todo list http://designfiles.org/skdb/doc/proposals/trans-tech.yaml | 17:12 |
kanzure | but now that i look at it, the todo list needs some updating | 17:12 |
kanzure | bdesk: i used to host hplusroadmap-wiki ("biohack") on heybryan.org until i lost the hdd with the mysql database | 17:12 |
kanzure | i supposedly still have the hdd somewhere in a closet.. uh.. | 17:12 |
bdesk | ok thanks | 17:13 |
kanzure | bdesk: if you pester us, we'll assemble a list | 17:13 |
ybit | no more lists plz | 17:14 |
kanzure | huh? | 17:14 |
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ybit | i'm tired of making a list of my projects :P | 17:14 |
ybit | think what we need is a website that gets people up-to-date on all the projects | 17:15 |
kanzure | oh boy.. yet another website | 17:15 |
ybit | yup | 17:15 |
kanzure | why not just a .txt file | 17:15 |
ybit | you can make it easier for people to navigate with html | 17:15 |
kanzure | it's a list, ybit.. | 17:16 |
ybit | i suppose | 17:16 |
ybit | anywho | 17:16 |
ybit | bdesk: any particular field you are interested in? | 17:16 |
bdesk | no i was just wondering which projects are active. i assume there are a ton of inactive projects for each active project. | 17:17 |
ybit | you would be correct, sir | 17:19 |
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brunsgenus | Does anyone have any theories on biological immortality? | 17:31 |
bdesk | brunsgenus: aubrey de grey | 17:31 |
bdesk | WILT | 17:31 |
brunsgenus | another question | 17:34 |
brunsgenus | fucking magnets, how do they work? | 17:34 |
kanzure | virtual photons | 17:34 |
kanzure | (ask feynman) | 17:34 |
brunsgenus | http://www.youtube.com/watch?v=RQWksKNrJm0 | 17:34 |
brunsgenus | ^ fucking magnets how do they work? | 17:34 |
brunsgenus | kanzure | 17:35 |
brunsgenus | please watch that | 17:35 |
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brunsgenus | streetyl | 17:36 |
brunsgenus | i have a question, please try to answer it after the video | 17:36 |
brunsgenus | ^ fucking magnets how do they work? | 17:36 |
brunsgenus | http://www.youtube.com/watch?v=RQWksKNrJm0 | 17:36 |
brunsgenus | magic everywhere in this bitch | 17:38 |
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bdesk | http://www.cs.uku.fi/~katajama/youwouldnt/xyz.gif | 18:05 |
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kanzure | bdesk: i would.. | 18:09 |
bdesk | skdb has an unfortunate google profile | 18:12 |
kanzure | yeah i'm no good at naming shit | 18:13 |
bdesk | i think it's fine, at least the project names are not blatantly scatological. | 18:16 |
kanzure | scat knowledge db, yo | 18:17 |
pmetzger | moo | 18:20 |
pmetzger | bdesk: I'm an academic | 18:20 |
pmetzger | so much for my bike for a couple of days. cable to the gear hub broke. :| | 18:20 |
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brunsgenus | cluckj: much like cancer cells, some of the cells present in Turritopsis dohrnii are able to selectively turn certain genes on or off and allow for the genetic programs that were present in earlier stages of the life cycle to be reactivated. | 19:10 |
brunsgenus | Read more at Suite101: The Immortal Jellyfish: Turritopsis Dohrnii http://fishinsects.suite101.com/article.cfm/the-immortal-jellyfish#ixzz0sfwhNIBx | 19:10 |
pmetzger | if only we were jellyfish. | 19:10 |
pmetzger | but then we'd have more trouble using the internet. | 19:11 |
brunsgenus | I am a jellyfish | 19:11 |
pmetzger | I had suspected. | 19:11 |
brunsgenus | You had better watch out, or else I will sting you | 19:13 |
pmetzger | Thanks. I will remain perpetually on guard for that eventuality. | 19:14 |
* brunsgenus edges towards pmetzger | 19:14 | |
* brunsgenus raises tentacle..... | 19:15 | |
* pmetzger removes a cuisinart and a copy of "how to cook jellyfish 800 different ways" from his backpack. | 19:15 | |
* brunsgenus glares at pmetzger | 19:15 | |
brunsgenus | you have won this round fair human... | 19:16 |
pmetzger | there are advantages to being at the top of the food chain. | 19:16 |
* brunsgenus strings pmetzger | 19:16 | |
AJollyLife | like not having other things eat you? | 19:16 |
brunsgenus | You have 10 minutes to live | 19:16 |
brunsgenus | spend it wisely. | 19:16 |
bdesk | every cell selectively turns certain genes on or off. this is what transcriptional regulation is. i guess they are talking about cell 'potency'. also i wonder if the transdifferentiation also re-elongates the telomeres. | 19:16 |
pmetzger | strangely, I feel just the same as before. | 19:16 |
brunsgenus | "Turritopsis undergoes cycles of de-development (return to a pre-adult state, which means it has no long-lived non-dividing cells. We rely on such cells for brain function among other things. Thus, even if we understood the genetic basis of how Turritopsis does ewhat it does (which we don't), we would not want to use it on ourselves. " -Aubrey de Grey | 19:17 |
pmetzger | they probably get cancers, too. | 19:17 |
pmetzger | though they might have unusually good mechanisms to stop that. | 19:18 |
pmetzger | it is generally difficult to avoid cancers if you last long enough though. | 19:18 |
bdesk | although de-development reverses one aspect of aging, there are other aspects of aging that this might not address. | 19:18 |
brunsgenus | My friend was talking about studying artificial cancer aimed at neurons in order to make the concentrations of neurons higher in certain regions of brain | 19:18 |
pmetzger | that's nice. | 19:19 |
bdesk | cool | 19:19 |
bdesk | well cool for the mice but i wouldn't want it yet | 19:19 |
brunsgenus | well, what do you all think about it.... | 19:19 |
pmetzger | It sounds like gobbledygook. :) | 19:19 |
brunsgenus | lol | 19:19 |
brunsgenus | I feel bad for mice | 19:20 |
brunsgenus | I have two ferrets | 19:20 |
brunsgenus | lol | 19:20 |
bdesk | do the ferrets eat mice? | 19:20 |
brunsgenus | They eat ferret food >:| | 19:20 |
bdesk | but in the wild they eat mice right? | 19:20 |
brunsgenus | I don't think so | 19:20 |
pmetzger | do ferrets get artificial brain cancers to increase the number of neurons in their brains? | 19:20 |
brunsgenus | I saw my ferret eat a cockroach one time | 19:20 |
pmetzger | they eat mice. | 19:21 |
brunsgenus | nuh uh | 19:21 |
brunsgenus | mine dont | 19:21 |
pmetzger | in general. | 19:21 |
pmetzger | mice, voles, rabbits. | 19:21 |
pmetzger | much like cats. | 19:21 |
brunsgenus | my cats eat catfood | 19:22 |
pmetzger | I'm sure they do. | 19:23 |
pmetzger | later. | 19:24 |
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bdesk | http://en.wikipedia.org/wiki/Ferret_legging | 19:26 |
brunsgenus | WHAT | 19:27 |
brunsgenus | lol | 19:27 |
brunsgenus | I have a ferret in my pants. | 19:27 |
brunsgenus | http://openwetware.org/images/3/3d/SB_Primer_100707.pdf | 19:42 |
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kanzure | bdesk: see pm | 20:01 |
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ybit | where's part 2 and 3 to that? | 21:04 |
ybit | nice find br | 21:04 |
ybit | er.., guess he left since tabbing didn't work | 21:05 |
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brunsgenus | BROCK LESNOR WON | 21:17 |
brunsgenus | FUCK YES | 21:17 |
ybit | brunsgenus: do you know if 2 or 3 had been made? | 21:22 |
ybit | of the synbio primer | 21:23 |
ybit | +part 2 or 3 | 21:23 |
brunsgenus | no clue | 21:24 |
brunsgenus | Can you fill me in? | 21:24 |
brunsgenus | ybit ^ | 21:26 |
ybit | [15:33:31] <brunsgenus> http://openwetware.org/images/3/3d/SB_Primer_100707.pdf | 21:27 |
brunsgenus | oh I was reading this earlier | 21:28 |
brunsgenus | eh | 21:29 |
brunsgenus | I don't think 2 or 3 are on there | 21:29 |
brunsgenus | only 1 | 21:29 |
ybit | google says the same | 21:29 |
brunsgenus | I wanna buy the Turritopsis | 21:31 |
brunsgenus | ybit when do you think these might be released | 21:32 |
ybit | dunno, probably best to contact the authors | 21:32 |
brunsgenus | if i can get a name I can get a phone number | 21:33 |
brunsgenus | give me a sec | 21:33 |
brunsgenus | come to think about it....calling someone randomly to ask them this question seems like a bad idea | 21:34 |
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