--- Log opened Tue Nov 09 00:00:08 2010 | ||
-!- streety [~Jonathan@host86-161-101-83.range86-161.btcentralplus.com] has joined #hplusroadmap | 00:28 | |
-!- archels [~neuralnet@unaffiliated/archels] has quit [Ping timeout: 272 seconds] | 00:28 | |
-!- archels [~neuralnet@541EEC68.cm-5-7d.dynamic.ziggo.nl] has joined #hplusroadmap | 00:41 | |
-!- JaredWigmore [~JaredW@219-89-11-117.dialup.xtra.co.nz] has joined #hplusroadmap | 01:22 | |
-!- JaredW [~JaredW@122-57-80-104.jetstream.xtra.co.nz] has quit [Ping timeout: 265 seconds] | 01:22 | |
-!- streety [~Jonathan@host86-161-101-83.range86-161.btcentralplus.com] has quit [Ping timeout: 252 seconds] | 01:22 | |
-!- JaredWigmore is now known as JaredW | 01:24 | |
-!- genehacker [~notanemai@cpe-70-112-176-113.austin.res.rr.com] has joined #hplusroadmap | 01:33 | |
-!- flamt_ [~root@bas5-barrie18-2925347894.dsl.bell.ca] has quit [Read error: Operation timed out] | 01:34 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has joined #hplusroadmap | 01:37 | |
archels | < ybit2> i often doubt my ability to save the human race < ybit2> because of time constraints | 01:49 |
---|---|---|
archels | haha | 01:49 |
-!- archels [~neuralnet@541EEC68.cm-5-7d.dynamic.ziggo.nl] has quit [Changing host] | 01:53 | |
-!- archels [~neuralnet@unaffiliated/archels] has joined #hplusroadmap | 01:53 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has quit [Ping timeout: 255 seconds] | 01:57 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has joined #hplusroadmap | 01:59 | |
archels | Shit, there was an ImmInst conference in Belgium? | 02:03 |
-!- Redeemer [~lorddeeme@c-75-72-218-226.hsd1.mn.comcast.net] has joined #hplusroadmap | 02:10 | |
-!- marainein [~marainein@220-253-50-237.VIC.netspace.net.au] has joined #hplusroadmap | 02:15 | |
-!- killall-9 [~paulc@diana.null.ro] has joined #hplusroadmap | 02:18 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has quit [Ping timeout: 252 seconds] | 03:31 | |
-!- JaredW [~JaredW@219-89-11-117.dialup.xtra.co.nz] has quit [Ping timeout: 240 seconds] | 03:33 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has joined #hplusroadmap | 03:33 | |
-!- JaredW [~JaredW@219-89-10-78.dialup.xtra.co.nz] has joined #hplusroadmap | 03:33 | |
-!- genehacker [~notanemai@cpe-70-112-176-113.austin.res.rr.com] has quit [Ping timeout: 240 seconds] | 03:34 | |
-!- genehacker [~notanemai@cpe-70-112-176-113.austin.res.rr.com] has joined #hplusroadmap | 03:38 | |
-!- jennifer2 [~jennifer@70-36-134-52.dsl.dynamic.sonic.net] has quit [Remote host closed the connection] | 03:46 | |
-!- marainein [~marainein@220-253-50-237.VIC.netspace.net.au] has quit [Ping timeout: 240 seconds] | 03:53 | |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has joined #hplusroadmap | 04:06 | |
-!- niftyzero [~miron@dsl081-070-214.sfo1.dsl.speakeasy.net] has quit [Ping timeout: 265 seconds] | 04:07 | |
-!- niftyzero1 [~miron@dsl081-070-214.sfo1.dsl.speakeasy.net] has quit [Ping timeout: 276 seconds] | 04:08 | |
-!- niftyzero1 [~miron@dsl081-070-214.sfo1.dsl.speakeasy.net] has joined #hplusroadmap | 04:11 | |
-!- niftyzero [~miron@dsl081-070-214.sfo1.dsl.speakeasy.net] has joined #hplusroadmap | 04:21 | |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has quit [Quit: mheld] | 04:36 | |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has joined #hplusroadmap | 04:37 | |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has joined #hplusroadmap | 05:07 | |
-!- genehacker [~notanemai@cpe-70-112-176-113.austin.res.rr.com] has quit [Ping timeout: 240 seconds] | 05:11 | |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has quit [Quit: This computer has gone to sleep] | 05:13 | |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has joined #hplusroadmap | 05:19 | |
-!- genehacker [genehacker@wireless-128-62-153-22.public.utexas.edu] has joined #hplusroadmap | 05:22 | |
-!- t_siamendes [t_siamende@host217-43-27-27.range217-43.btcentralplus.com] has joined #hplusroadmap | 05:48 | |
-!- JayDugger [~duggerj@pool-173-74-76-197.dllstx.fios.verizon.net] has joined #hplusroadmap | 06:01 | |
-!- industromatic [~chatzilla@cpe-66-68-104-159.austin.res.rr.com] has quit [Ping timeout: 250 seconds] | 06:06 | |
-!- industromatic [~chatzilla@cpe-66-68-104-159.austin.res.rr.com] has joined #hplusroadmap | 06:07 | |
-!- nsh_ [~nsh@pubble.infomesh.net] has quit [Quit: Leaving.] | 06:22 | |
-!- wolfspraul [~wolfsprau@lucia.q-ag.de] has quit [Quit: leaving] | 07:05 | |
-!- codeshepherd_ [~Deepan@122.167.91.238] has joined #hplusroadmap | 07:17 | |
-!- codeshepherd [~Deepan@122.166.151.8] has quit [Ping timeout: 252 seconds] | 07:21 | |
-!- codeshepherd_ is now known as codeshepherd | 07:21 | |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has quit [Quit: mheld] | 07:23 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has joined #hplusroadmap | 07:26 | |
-!- codeshepherd [~Deepan@122.167.91.238] has quit [Quit: codeshepherd] | 07:28 | |
-!- mheld [~mheld@c-75-69-89-109.hsd1.ma.comcast.net] has joined #hplusroadmap | 07:57 | |
kanzure | ide thingy for openscad/repg/skeinforge http://fabbaloo.com/blog/2010/11/8/rapcad-announced.html | 08:07 |
kanzure | hillis knowledge database or why wikipedia sucks http://edge.org/3rd_culture/hillis10/hillis10_index.html | 08:11 |
kanzure | oops i might have meant http://edge.org/3rd_culture/hillis04/hillis04_index.html | 08:11 |
industromatic | rapcad sounds like a GUI is all. | 08:12 |
kanzure | although he poses it as a learning thing. whatever. | 08:12 |
kanzure | industromatic: yeah :/ | 08:12 |
industromatic | Bryan, what microfluidic set of parts would sell best to diybio folks? | 08:18 |
industromatic | I'm thinking of a microscope slide mount with ports and a diverter that works with a piezo driver to push to and fro. | 08:19 |
industromatic | A diverter would be used with microscope for slow hand sorting, and with emitter detector for fast sorts. | 08:20 |
industromatic | any of that needs good macro connecting tubing that is very limp. | 08:20 |
industromatic | I like the idea of simple push fit ports that tubing shoves into for a seal. | 08:21 |
industromatic | All out of glass bonded at boiling water temps with sodium silicate. | 08:21 |
-!- genehacker2 [genehacker@wireless-128-62-153-22.public.utexas.edu] has joined #hplusroadmap | 08:23 | |
-!- genehacker [genehacker@wireless-128-62-153-22.public.utexas.edu] has quit [Ping timeout: 250 seconds] | 08:26 | |
-!- mheld [~mheld@c-75-69-89-109.hsd1.ma.comcast.net] has left #hplusroadmap [] | 08:27 | |
kanzure | industromatic: a plug-and-play jigsaw puzzle system | 08:28 |
kanzure | Fast and reliable way to establish fluidic connections to planar microchips http://bio.cc/Bioinformics/papers/microfluidics/Fast%20and%20reliable%20way%20to%20establish%20fluidic%20connections%20to%20planar%20microchips%20-%20straws%20-%20glue%20-%20Snakenborg%20-%202007.pdf | 08:28 |
kanzure | Interconnectable blocks - a method for providing reusable, rapid, multiple aligned and planar microfluidic interconnections http://bio.cc/Bioinformics/papers/microfluidics/Interconnectable%20blocks%20-%20a%20method%20for%20providing%20reusable,%20rapid,%20multiple,%20aligned%20and%20planar%20microfluidic%20interconnections%20-%20Snakenborg%20-%202009.pdf | 08:29 |
kanzure | Macro-to-macro interfaces http://bio.cc/Bioinformics/papers/microfluidics/Macro-to-micro%20interfaces%20for%20microfluidic%20devices.pdf | 08:29 |
kanzure | Microfluidic assembly blocks http://bio.cc/Bioinformics/papers/microfluidics/Microfluidic%20assembly%20blocks.pdf | 08:29 |
kanzure | Microfluidic motherboards and interconnects http://bio.cc/Bioinformics/papers/microfluidics/Microfluidic%20motherboard%20-%20has%20a%20good%20list%20of%20different%20types%20of%20interconnections%20from%20the%20literature.pdf | 08:29 |
kanzure | another paper i recall used straws and bubble gum for ports. i imagine rubber cement or something like it would work fine too. straw diameter might be too large. | 08:30 |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has quit [Quit: This computer has gone to sleep] | 08:33 | |
industromatic | I'm thinking of products that go beyond bubble gum, but are not an array of legos either. | 08:36 |
industromatic | Can't think of ways to get lego block fluidics. | 08:37 |
kanzure | those articles show "lego block" fluidics (sort of) | 08:37 |
kanzure | why are syringe pumps so expensive? | 08:39 |
industromatic | "lego block" fluidics could be done if you could make a 3D flange accurately line up with edge ports. | 08:46 |
-!- archels [~neuralnet@unaffiliated/archels] has quit [Ping timeout: 255 seconds] | 08:47 | |
kanzure | you could maybe have the blocks lock together but also on a 2d surface (plexiglass?) | 08:47 |
industromatic | I'm searching for good teeny tubing. That could define most of it. | 08:47 |
kanzure | plexiglass -> put down block pieces into whatever pattern (interconnected) -> sandwhich plexiglass again & tighten it down like hell | 08:47 |
kanzure | *sandwich | 08:48 |
industromatic | Yeah, the 4mm tall IB interconnect blocks seeems good. | 08:48 |
kanzure | another scare article on diybio (well, not entirely) http://www.dodbuzz.com/2010/11/08/seven-terror-tech-trends/ | 08:51 |
kanzure | haha someone's commentary on that article :) http://www.ph2dot1.com/2010/11/hoo-boy.html | 08:52 |
industromatic | I like capillary glass tubes for lining up with a port out of a planar surface, but there's no good o-ring method. | 08:54 |
kanzure | how are you propelling the liquids? | 08:54 |
industromatic | So finding teeny teflon tubing seems the thing. | 08:54 |
kanzure | surface tension? margonelli forces? lasers/explosions? hydrualics/pumps? pneumatics? gravity? | 08:54 |
industromatic | propelling the liquids? Oh, haven't gotten that far. | 08:54 |
kanzure | it greatly influences design decisions | 08:55 |
industromatic | pos disp. pumps seem best sellers. | 08:55 |
-!- Redeemer [~lorddeeme@c-75-72-218-226.hsd1.mn.comcast.net] has quit [Ping timeout: 252 seconds] | 08:55 | |
industromatic | Theyhave to be micro smooththough. | 08:55 |
-!- genehacker2 [genehacker@wireless-128-62-153-22.public.utexas.edu] has quit [Ping timeout: 252 seconds] | 08:57 | |
-!- archels [~neuralnet@541EEC68.cm-5-7d.dynamic.ziggo.nl] has joined #hplusroadmap | 09:02 | |
industromatic | Maybe an ethernet syringe pump would be a good first product -- not even microfluidic, just Luer lock. | 09:03 |
-!- metaliving [~victorere@129.133.146.26] has quit [Ping timeout: 260 seconds] | 09:04 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has quit [Ping timeout: 245 seconds] | 09:05 | |
-!- nsh_ [~nsh@pubble.infomesh.net] has joined #hplusroadmap | 09:25 | |
kanzure | miriam leis again.. skdb = Repo(owner=kanzure, name="skdb") | 09:30 |
kanzure | er | 09:30 |
kanzure | http://www.synthethics.eu/ | 09:30 |
dbolser | Focus Issue of Chaos: Intrinsic and Designed Computation: Information Processing in Dynamical Systems--Beyond the Digital Hegemony | 09:33 |
dbolser | http://maestro.aip.org/trk/click?ref=zstq4sfk3_0-45ex38bax3183875& | 09:33 |
dbolser | Chaogates: Morphing logic gates that exploit dynamical patterns | 09:35 |
dbolser | http://maestro.aip.org/trk/click?ref=zstq4sfk3_0-45ex38bfx3183875& | 09:35 |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has joined #hplusroadmap | 09:37 | |
industromatic | After reading the paper on IBs, I'm sold. Glass "chips" could be edge ground and polished just as the PMMA boded ones they used. | 09:38 |
kanzure | :) | 09:38 |
kanzure | snakenborg's paper? | 09:38 |
industromatic | Yep. snakenborg. | 09:39 |
kanzure | what an awesome name | 09:39 |
industromatic | Wonder if that is legally locked anywhere? | 09:39 |
kanzure | ? | 09:39 |
industromatic | Even Snakenborg's methods don't attempt a grid of building block microfluidics, just a standardized edge connect for most any "chip". | 09:41 |
industromatic | Snakenborg's needle attach block is so close together they used one port at a time. Limiting. | 09:44 |
dbolser | what is the limit of protein quantification 'on-a-chip'? | 09:45 |
kanzure | you mean chromatography or what ? | 09:45 |
dbolser | i.e. can you make a chip to detect cancer marker proteins? | 09:45 |
kanzure | yes | 09:45 |
kanzure | but it would involve some extra hardware :P | 09:45 |
dbolser | ah... | 09:45 |
kanzure | for instance, there was a chromatography-on-a-chip setup i saw | 09:45 |
dbolser | so the chip would do separation? | 09:45 |
dbolser | right | 09:45 |
kanzure | there's also other ways though | 09:46 |
kanzure | like if you used antibodies or aptamers | 09:46 |
dbolser | I'm wondering what the limit of protein identification is | 09:46 |
dbolser | in terms of miniaturization | 09:46 |
kanzure | i'm sorry but what do you mean "the limit" | 09:46 |
industromatic | An attach block that fans out to luerlocks would be good. | 09:47 |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has quit [Quit: Leaving] | 09:47 | |
kanzure | industromatic: also check out http://bio.cc/Bioinformics/papers/microfluidics/Fast%20and%20reliable%20way%20to%20establish%20fluidic%20connections%20to%20planar%20microchips%20-%20straws%20-%20glue%20-%20Snakenborg%20-%202007.pdf | 09:48 |
dbolser | kanzure: sorry, bad way of trying to summarise | 09:48 |
industromatic | dbolser: Some mass spec by MEMS beam mass change detectors could do somethinng if they had zones that would attract proteins on the vibrating beams. | 09:48 |
dbolser | what is the cheapest way to do protein identification? | 09:48 |
dbolser | ic | 09:49 |
kanzure | you could also separate proteins by mass via gravity | 09:50 |
-!- shepazu [~schepers@adsl-69-180-150.rmo.bellsouth.net] has quit [Ping timeout: 252 seconds] | 09:50 | |
kanzure | gravity: http://bio.cc/Bioinformics/papers/microfluidics/A%20Gravity-Driven%20Microfluidic%20Particle%20Sorting%20Device%20with%20Hydrodynamic%20Separation%20Amplification.pdf | 09:50 |
kanzure | gravity: http://bio.cc/Bioinformics/papers/microfluidics/Hydrodynamic%20filtration%20for%20on-chip%20particle%20concentration%20and%20classification%20utilizing%20microfluidics.pdf | 09:50 |
-!- shepazu [~schepers@adsl-69-168-60.rmo.bellsouth.net] has joined #hplusroadmap | 09:50 | |
kanzure | again: http://bio.cc/Bioinformics/papers/microfluidics/In-channel%20focusing%20of%20flowing%20microparticles%20utilizing%20hydrodynamic%20filtration.pdf | 09:51 |
dbolser | hmmm | 09:51 |
t_siamendes | proteins have novel shapes/folds so it shouldnt be too hard to id them from that | 09:51 |
dbolser | t_siamendes: indeed, they are clearly distinguishable when xtalized and blasted with x-rays ;-) | 09:51 |
kanzure | i like aptamers/antibodies because you can have a binding event involving, say, light/glowing | 09:51 |
kanzure | and then you just take a picture | 09:51 |
dbolser | kanzure: so we just need a biomarker ab array | 09:52 |
kanzure | spiral microfluidic nanoparticle separator http://bio.cc/Bioinformics/papers/microfluidics/Spiral%20microfluidic%20nanoparticle%20separators.pdf | 09:52 |
dbolser | kanzure: can I s/particle/protein/ in all these tools? | 09:53 |
dbolser | why does bio.cc sound familiar... | 09:53 |
kanzure | heh | 09:53 |
kanzure | uh | 09:53 |
kanzure | don't tell please :( | 09:54 |
kanzure | i hid the files on there | 09:54 |
dbolser | btw, are you here: http://groups.google.com/group/biocc-server-interface/pendmsg?hl=en-GB_GB&pli=1 | 09:54 |
dbolser | ;-) | 09:54 |
dbolser | oh... bad link | 09:54 |
dbolser | http://groups.google.com/group/biocc-server-interface?hl=en-GB_GB | 09:54 |
kanzure | presumably i have an account there but i don't know where to ssh into | 09:55 |
dbolser | kanzure: they set up an ip based ssh filter | 09:55 |
kanzure | lovely :( | 09:55 |
dbolser | you can get an account on ssh.biomama.org | 09:55 |
dbolser | which is for all IPs | 09:55 |
dbolser | (you can ssh bio.cc from biomama | 09:56 |
kanzure | ssh.biomama.org doesn't resolve | 09:56 |
dbolser | sorry, .com | 09:56 |
kanzure | connection refused on port 22 | 09:56 |
dbolser | 2022 | 09:56 |
kanzure | picky. | 09:56 |
kanzure | hmm my old password doesn't work | 09:57 |
dbolser | right, you'll need a new one. Please ask jongbhak@yahoo.com and cc whtndks81@gmail.com | 09:57 |
kanzure | k | 09:57 |
dbolser | he said they just ordered 'hundreds' of Tb disks... | 09:58 |
dbolser | should be fun ;-) | 09:58 |
dbolser | night | 09:58 |
kanzure | dbolser: have you seen library genesis? | 09:58 |
kanzure | http://free-books.dontexist.com/ | 09:58 |
kanzure | it's a couple TB torrent | 09:58 |
dbolser | cool | 09:58 |
dbolser | didn't look in detail yet | 09:58 |
dbolser | Utopiah: pointed me at it | 09:59 |
-!- shepazu [~schepers@adsl-69-168-60.rmo.bellsouth.net] has quit [Ping timeout: 245 seconds] | 10:05 | |
-!- streety [~Jonathan@host109-153-27-254.range109-153.btcentralplus.com] has joined #hplusroadmap | 10:14 | |
-!- streety [~Jonathan@host109-153-27-254.range109-153.btcentralplus.com] has quit [Ping timeout: 245 seconds] | 10:18 | |
-!- genehacker [genehacker@wireless-128-62-237-28.public.utexas.edu] has joined #hplusroadmap | 10:18 | |
-!- genehacker [genehacker@wireless-128-62-237-28.public.utexas.edu] has quit [Ping timeout: 245 seconds] | 10:31 | |
-!- genehacker [genehacker@wireless-128-62-177-172.public.utexas.edu] has joined #hplusroadmap | 10:35 | |
industromatic | I read the older Snakenborg paper and searched for patent fluidic interconnection block and no hits. | 10:50 |
industromatic | What if you molded thick "gaskets" like his IBs so the through holes could be molded around wires that are shorter? | 10:52 |
industromatic | That might make it less laborious to mold. | 10:53 |
kanzure | did you search for patents in the .dk or where-ever he's authoring from? | 10:54 |
kanzure | (not that it matters) | 10:54 |
-!- genehacker [genehacker@wireless-128-62-177-172.public.utexas.edu] has quit [Ping timeout: 245 seconds] | 10:56 | |
industromatic | just googled "patent fluidic interconnection block". | 10:59 |
kanzure | oh, you should google patent and snakenborg instead | 10:59 |
industromatic | Snakenborg used 250 um POFbier as mold for the channels in his IBs -- that's the size of some wire also. | 11:01 |
kanzure | here: | 11:01 |
kanzure | http://www.dtu.dk/English/Service/Phonebook.aspx?lg=showcommon&id=25156&type=publications | 11:01 |
kanzure | there's a few patents | 11:01 |
kanzure | nothing relevant | 11:02 |
kanzure | One-step fabrication of microfluidic chips with in-plane, adhesive-free interconnections" | 11:02 |
kanzure | that was http://www.dtu.dk/English/Service/Phonebook.aspx?lg=showcommon&id=261816 | 11:02 |
-!- nchaimov [~cowtown@c-71-59-157-3.hsd1.or.comcast.net] has quit [Quit: nchaimov] | 11:06 | |
industromatic | >nothing relevant that I saw wither | 11:07 |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has joined #hplusroadmap | 11:09 | |
-!- killall-9 [~paulc@diana.null.ro] has quit [Quit: Leaving] | 11:11 | |
kanzure | hmm i do not feel good about this | 11:16 |
-!- nchaimov [~cowtown@c-71-59-157-3.hsd1.or.comcast.net] has joined #hplusroadmap | 11:16 | |
kanzure | in order to be more "relevant" humanity+ is thinking about an "H+ stamp of approval" for tech projects | 11:16 |
kanzure | namely, other people who are doing work get the "privledge" of adding the Humanity+ stamp of approval | 11:17 |
kanzure | imho this is a disasterous idea | 11:17 |
kanzure | personally i wouldn't want the Humanity+ stamp on any of my projects | 11:17 |
kanzure | since the organization is such an embarrassing failure | 11:17 |
industromatic | you'r e in a funk over "H+ stamp of approval"? | 11:22 |
industromatic | I looked at the patents and thought aboutthe papers and the IB concept is so like a gasket it proably won't patent. | 11:23 |
-!- genehacker [genehacker@wireless-128-62-237-28.public.utexas.edu] has joined #hplusroadmap | 11:23 | |
industromatic | IBs also have integral o-rings, which also is prior art. | 11:23 |
kanzure | not a funk- just some email exchanges going on. doesn't matter | 11:24 |
kanzure | are these PMMA or PDMA? | 11:24 |
kanzure | ybit had an SU8 lithography setup a while back | 11:24 |
kanzure | wonder if he still uses that | 11:24 |
industromatic | The IBs are molded of silicone | 11:24 |
industromatic | SU8 == ? | 11:25 |
industromatic | SU8 is a photoresist? | 11:26 |
-!- genehacker [genehacker@wireless-128-62-237-28.public.utexas.edu] has quit [Ping timeout: 245 seconds] | 11:27 | |
industromatic | The edges of 2-layer bonded microfluidics they connect to are PMMA, but glass will work fine also. | 11:27 |
industromatic | I could see developing some glass parts that are autoclavable, reused, and micromachined molds for silicone sealer gaskets that are many uses. | 11:28 |
industromatic | Instead of the needle attach blocks of silicone, I would make those of hard plastic or glass/epoxied asesmblies to luer locks or something smaller for tubes. | 11:30 |
kanzure | with a luer lock multiple blocks wouldn't be flesh next to each other, would they? | 11:31 |
kanzure | flush | 11:32 |
kanzure | not flesh :) | 11:32 |
industromatic | luer lock is 4mm. and big syringes plug into or connectors with about 8mm size, so that would need fan out. | 11:32 |
kanzure | big syringes can have different i/o ports on the blocks (like on the top/bottom surfaces) | 11:32 |
kanzure | i was thinking the blocks themselves would connect to other blocks by the edges (the surface that has the depth of the block/chip) | 11:33 |
industromatic | Without making a sketch, start from syringe driven tube, then luer to a lbock that fans in four paths, then a IB, then glass with anything, and optionally another set of IB and luer or just drains or ?? | 11:34 |
industromatic | "big syringes can have different i/o ports" I would skip anything like that, and keep all multiport stuff in the micro size range. | 11:35 |
industromatic | I think you can buy luer to tube where the tube is .5mm ID 500 um. | 11:36 |
kanzure | industromatic: http://diyhpl.us/~bryan/irc/microfluidic_interconnectable_blocks.png crude diagram | 11:45 |
kanzure | nothing to scale :P | 11:50 |
-!- genehacker [genehacker@wireless-128-62-174-96.public.utexas.edu] has joined #hplusroadmap | 12:19 | |
-!- genehacker [genehacker@wireless-128-62-174-96.public.utexas.edu] has quit [Ping timeout: 245 seconds] | 12:23 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has quit [Ping timeout: 245 seconds] | 12:24 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has joined #hplusroadmap | 12:26 | |
industromatic | Bryan: your diagram looks like a thing that Snakenborg DID patent. A holder for many chips and interconnects. | 12:28 |
kanzure | hmm | 12:28 |
kanzure | link to the patent? | 12:28 |
industromatic | I'll look. | 12:28 |
industromatic | here: http://www.europatentbox.com/patent/EP2108452A1/abstract/190659.html | 12:28 |
industromatic | To get some of the images that tell you what I mean, use the link to full doc .pdf | 12:29 |
kanzure | hmm if the image on that link is to be believed, then my idea is different | 12:30 |
kanzure | namely the concept of having a platform on which to plug the chips on to the surface, in any generic order | 12:30 |
kanzure | or whatever pattern. | 12:30 |
industromatic | It is just an app, not a patent. It covers adjustability and clamping is about all... | 12:30 |
kanzure | the image (Fig. 2) looks more like a jig | 12:30 |
industromatic | yes, jig and clamp. | 12:30 |
industromatic | yours has clear plate clamp also, just as his. | 12:31 |
kanzure | hmm i see | 12:32 |
kanzure | claim 13 is p. nice | 12:32 |
industromatic | A lego method could work. The pegs would need to be deep, so alignment could happen as you lower blocks in place with gaskets between. | 12:32 |
kanzure | right | 12:33 |
industromatic | How many could you connect at once? Depends on their interconnects...toomany fingers required... | 12:33 |
kanzure | huh? i'm hoping a final system ilke this would be exactly like a jigsaw puzzle except with standardized pieces | 12:35 |
-!- augur [~augur@208.58.6.161] has quit [Remote host closed the connection] | 12:35 | |
kanzure | industromatic: the snakenborg patent seems different from my idea in many ways; he basically has "an adjustable external hard drive enclosure" for chips | 12:36 |
kanzure | whereas i'm thinking of a sort of.. "breadboard" where components connect (except when they are flush or otherwise connected) | 12:36 |
-!- Noahj [~noa@24.38.179.66] has quit [Ping timeout: 240 seconds] | 12:42 | |
industromatic | "breadboard" has hurdles I know not how to scale. | 12:44 |
industromatic | Unless they connect underneath? | 12:45 |
industromatic | But then the bottom plate is complex and can plug, and how to make snake holes in it? | 12:46 |
kanzure | i was just using the word breadboard- rapid prototyping board on which you plug things into (or on top of), i don't think connecting the devices to the board/plate itself is necessary (except for clamping) | 12:47 |
industromatic | edge connections need side pressure to work, so how the jigsaw puzzle? | 12:47 |
kanzure | although the bottom board could have pegs on which the chips would fall in place to (as a way to "lock" them into place so they don't move around while you work) | 12:47 |
kanzure | hmm | 12:47 |
kanzure | well | 12:48 |
kanzure | i was hoping there might be a way to tighten them down enough for that :/ | 12:48 |
industromatic | Are yo thinking seals that are at most 1 atm + .2 ATM differential? | 12:48 |
kanzure | i wouldn't know the pressure ratings yet | 12:48 |
industromatic | The ohters were getting 5 ATM | 12:48 |
kanzure | this is pretty easy to test i think | 12:49 |
industromatic | If you really wanted lego-like, and accepted .2 ATM pressures, and large dead volumes, maybe... | 12:50 |
kanzure | where would the dead volumes be? | 12:50 |
kanzure | what's the pressure on lego snap-fits anyway | 12:50 |
industromatic | dead V is at each connect, where you have the human tolerable slop of +/-400 um. | 12:50 |
industromatic | lego side pressure can be big. | 12:51 |
kanzure | suppose the bottom plate had an array of pegs, on which the blocks could be dropped on to, which would lower the placement margin error | 12:51 |
industromatic | easy to test i think.... nothing ever is... test is the hard work. | 12:52 |
kanzure | although i don't know if i like that approach (board with pegs on it for each blog) | 12:52 |
kanzure | *block | 12:52 |
industromatic | snakenborg et al used pins -- same thing. | 12:53 |
industromatic | pins located for the squeeze action to create seals. | 12:53 |
industromatic | lego pegs same thing. | 12:53 |
industromatic | Here's a simpler connect goal using IB concept: http://ecosensory.com/diybio/microfluidic-blocks-1.jpg | 12:56 |
industromatic | In that I only squeeze in one dir, not jigsaw possibilities. | 12:56 |
industromatic | If not adjacent you could design pin plate for connect squeeze in 2 dirs. | 12:57 |
industromatic | The selling points for such a sys are: reuse the luer connect, luer transition, and output buckets across experiments. | 12:59 |
industromatic | Also reuse the IBs mostly... design "chips" on grids and they will reuse well. | 13:00 |
industromatic | ports on grids like 1mm | 13:00 |
industromatic | gotta work on income generating.... | 13:01 |
-!- jmil [~jmil@SEASNet-148-05.seas.upenn.edu] has joined #hplusroadmap | 13:19 | |
kanzure | hi jmil | 13:19 |
jmil | yo yo ma | 13:20 |
jmil | what's up | 13:20 |
-!- nchaimov_ [~cowtown@c-71-59-157-3.hsd1.or.comcast.net] has joined #hplusroadmap | 13:30 | |
-!- nchaimov [~cowtown@c-71-59-157-3.hsd1.or.comcast.net] has quit [Ping timeout: 265 seconds] | 13:33 | |
-!- nchaimov_ is now known as nchaimov | 13:33 | |
-!- augur [~augur@129.2.129.32] has joined #hplusroadmap | 13:55 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has quit [Ping timeout: 240 seconds] | 14:17 | |
-!- flamt [~root@bas5-barrie18-2925347894.dsl.bell.ca] has joined #hplusroadmap | 14:18 | |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has joined #hplusroadmap | 14:20 | |
-!- jmil [~jmil@SEASNet-148-05.seas.upenn.edu] has quit [Quit: jmil] | 15:01 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has quit [Quit: Leaving] | 15:02 | |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has quit [Ping timeout: 272 seconds] | 15:16 | |
-!- Noahj [~noa@24.38.179.66] has joined #hplusroadmap | 15:40 | |
Utopiah | IEEE International Symposium on Rapid System Prototyping (RSP) http://www.rsp-symposium.org | 15:57 |
kanzure | a study on etsy/instructables/"DIY" http://staceyk.org/hci/KuznetsovDIY.pdf | 15:57 |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has joined #hplusroadmap | 16:07 | |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has joined #hplusroadmap | 16:14 | |
QuantumG | NASA's CTO Bobby Braun will be on The Space Show on Friday. Send your questions to DrSpace@thespaceshow.com | 16:16 |
-!- mheld [~mheld@pool-173-76-224-45.bstnma.fios.verizon.net] has left #hplusroadmap [] | 16:17 | |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has joined #hplusroadmap | 16:32 | |
joshcryer | http://www.worldenergyoutlook.org/docs/weo2010/weo2010_london_nov9.pdf | 16:35 |
joshcryer | WEO -> peak oil upon us | 16:36 |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has quit [Ping timeout: 240 seconds] | 16:37 | |
-!- technetium_s [t_siamende@host217-43-29-181.range217-43.btcentralplus.com] has joined #hplusroadmap | 16:39 | |
-!- t_siamendes [t_siamende@host217-43-27-27.range217-43.btcentralplus.com] has quit [Disconnected by services] | 16:40 | |
-!- technetium_s is now known as t_siamendes | 16:40 | |
joshcryer | Main site btw: http://www.worldenergyoutlook.org/ (if not obvious) | 16:41 |
-!- augur [~augur@129.2.129.32] has quit [Remote host closed the connection] | 16:42 | |
QuantumG | yawn | 16:43 |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has joined #hplusroadmap | 16:47 | |
joshcryer | This is the first time the IEA has predicted production falloff. | 16:48 |
joshcryer | Even if you don't think Peak Oil is an issue (and I personally don't, to the extent that we won't be able to find other ways to extract resources, eg oil shale), it's sobering. | 16:49 |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has joined #hplusroadmap | 16:50 | |
-!- wolfspraul [~wolfsprau@lucia.q-ag.de] has joined #hplusroadmap | 16:51 | |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has quit [Read error: Connection reset by peer] | 16:52 | |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has joined #hplusroadmap | 16:53 | |
-!- shepazu [~schepers@adsl-242-204-155.rmo.bellsouth.net] has quit [Ping timeout: 240 seconds] | 16:57 | |
kanzure | ftp://free-books.dontexist.com/scimagz/ | 16:59 |
superkuh | Oh my. | 17:00 |
kanzure | wow they have the full tetrahedron letters | 17:00 |
superkuh | Thanks for the heads up, kanzure. | 17:00 |
joshcryer | Looks like it's about 4 gigs for that. | 17:01 |
joshcryer | What's Tetrahedron letters? | 17:01 |
kanzure | superkuh: there's a torrent on free-books.dontexist.com | 17:01 |
kanzure | it's a few terabytes in total | 17:01 |
joshcryer | How many seeders? Haha | 17:02 |
kanzure | joshcryer: tetrahedron letters is a lot of scientific papers about molecular biology, RNA, DNA, self-replication, theoretical organic chemistry, etc. | 17:02 |
kanzure | http://www.elsevier.com/wps/find/journaldescription.cws_home/233/description | 17:03 |
QuantumG | wow, this site is awesome | 17:05 |
joshcryer | QuantumG, http://i48.photobucket.com/albums/f234/Melanchthon/OilECoyote.jpg | 17:05 |
joshcryer | :P | 17:05 |
-!- shepazu [~schepers@adsl-69-179-253.rmo.bellsouth.net] has joined #hplusroadmap | 17:06 | |
joshcryer | Yeah, it's slow as fuck though, I'm trying to find the terabyte torrent but there's no... descriptions that I see. | 17:06 |
kanzure | uh one sec | 17:06 |
kanzure | it's probably being raped by the entire free world | 17:06 |
-!- shepazu [~schepers@adsl-69-179-253.rmo.bellsouth.net] has quit [Read error: Connection reset by peer] | 17:06 | |
joshcryer | Haha | 17:06 |
joshcryer | How'd you find it? | 17:07 |
kanzure | eugen leitl | 17:07 |
kanzure | http://eugen.leitl.org/ | 17:07 |
joshcryer | Epic collection, I assume it's just a collection of collections. | 17:07 |
-!- shepazu [~schepers@adsl-69-179-253.rmo.bellsouth.net] has joined #hplusroadmap | 17:07 | |
QuantumG | Francis_C._Moon-The_Machines_of_Leonardo_Da_Vinci_and_Franz_Reuleaux__Kinematics_of_Machines_from_the_Renaissance_to_the_20th_Century_(History_of_Mechanism_and_Machine_Science)-Springer(2007).pdf | 17:08 |
QuantumG | Herbert_Goldstein_et_al.-Classical_Mechanics-Addison-Wesley.pdf | 17:08 |
QuantumG | was just looking at these two books this morning and thinking "I should really read that stuff" and now I can download em | 17:09 |
kanzure | joshcryer: all of the relative torrents are in here: | 17:09 |
kanzure | ftp://free-books.dontexist.com/repository_torrent/0-319.rar | 17:09 |
-!- shepazutoo [~schepers@adsl-69-166-247.rmo.bellsouth.net] has joined #hplusroadmap | 17:09 | |
-!- jennifer2 [~jennifer@70-36-134-52.dsl.dynamic.sonic.net] has joined #hplusroadmap | 17:09 | |
kanzure | haha that's a 23 MB file. | 17:10 |
joshcryer | Haha | 17:10 |
joshcryer | I download a hundred gigs a month typically. | 17:10 |
joshcryer | It would take me two years to get this thing. | 17:11 |
joshcryer | Unless I set up a wifi AP swarm and leech from my neighbors. | 17:11 |
kanzure | hm wait that's not what i want | 17:11 |
-!- shepazu [~schepers@adsl-69-179-253.rmo.bellsouth.net] has quit [Ping timeout: 250 seconds] | 17:11 | |
joshcryer | I wanted to get "The elements of computing systems: building a modern computer from first principles" | 17:12 |
-!- JayDugger [~duggerj@pool-173-74-76-197.dllstx.fios.verizon.net] has quit [Quit: Leaving.] | 17:12 | |
-!- JayDugger [~duggerj@pool-173-74-76-197.dllstx.fios.verizon.net] has joined #hplusroadmap | 17:13 | |
kanzure | http://gen.lib.rus.ec/ might be faster | 17:13 |
kanzure | kolkhoz | 17:13 |
joshcryer | Thanks | 17:14 |
joshcryer | That actually loads, heh. | 17:14 |
joshcryer | They don't have it. :/ Aww. | 17:14 |
kanzure | maybe this is the torrent: | 17:15 |
kanzure | http://gen.lib.rus.ec/files/torrents_0-256.rar | 17:15 |
joshcryer | Aww, they don't have "The Hidden Language of Computer Hardware and Software" | 17:16 |
joshcryer | How dare them not have what I want. | 17:16 |
kanzure | torrents_0-256.rar is a tarbomb | 17:18 |
JayDugger | Good evening, everyone. | 17:29 |
kanzure | what is this? http://torrent.rus.ec/tracker.php?f=414 | 17:29 |
kanzure | maybe a generic tracker | 17:29 |
kanzure | http://home-lib.net/ | 17:30 |
kanzure | http://lib.ololo.cc/libdb/LibraryGenesis110k-torrents.7z | 17:36 |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has quit [Ping timeout: 255 seconds] | 17:39 | |
kanzure | oh well. i was hoping to check up on the health of those torrents. | 17:42 |
JayDugger | What do you use to translate the pages? | 17:42 |
kanzure | how will i learn if i translate? | 17:42 |
JayDugger | How's your Russian? :P | 17:42 |
JayDugger | Better than mine, obviously. | 17:43 |
kanzure | ????? ?????? | 17:43 |
JayDugger | Show off. | 17:43 |
JayDugger | I withdraw the question. | 17:44 |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has joined #hplusroadmap | 17:44 | |
kanzure | i could just go with ??@??~H????@??~H????@??~H????@??~H????@??~H?? | 17:44 |
kanzure | and pretend your client is broken | 17:44 |
joshcryer | Why learn Russian? | 17:44 |
joshcryer | Unless you plan to acquire a Russian bride. | 17:44 |
JayDugger | Or have Russian co-workers. | 17:45 |
kanzure | JayDugger: i think i meant something closer to "3to ??????" | 17:50 |
* kanzure grumbles something about key bindings | 17:50 | |
-!- t_siamendes [t_siamende@host217-43-29-181.range217-43.btcentralplus.com] has quit [Read error: Connection reset by peer] | 17:56 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has joined #hplusroadmap | 18:03 | |
JayDugger | After all...where else than Library Genesis would one find such useful titles as Naylor's "The Busy Brides Essential Wedding Checklists"? | 18:31 |
Redeemer | Kanzure, have ya figured out anything regarding hotel stuff? | 18:38 |
Redeemer | Correction, any ideas rather? | 18:38 |
kanzure | nope | 18:43 |
-!- Redeemer [~lorddeeme@c-75-72-237-18.hsd1.mn.comcast.net] has quit [Ping timeout: 276 seconds] | 18:43 | |
-!- JayDugger [~duggerj@pool-173-74-76-197.dllstx.fios.verizon.net] has quit [Quit: Leaving.] | 18:47 | |
-!- Redeemer [~lorddeeme@c-75-72-233-74.hsd1.mn.comcast.net] has joined #hplusroadmap | 19:11 | |
-!- eridu [debian-tor@gateway/tor-sasl/eridu] has quit [Quit: Leaving] | 19:13 | |
-!- industromatic [~chatzilla@cpe-66-68-104-159.austin.res.rr.com] has quit [Quit: ChatZilla 0.9.86 [Iceweasel 3.5.13/20101028104358]] | 19:25 | |
-!- QuantumG [~qg@rtfm.insomnia.org] has quit [Ping timeout: 240 seconds] | 19:25 | |
-!- klafka [~klafka@cpe-74-74-152-155.rochester.res.rr.com] has quit [Ping timeout: 240 seconds] | 19:37 | |
-!- augur [~augur@208-59-167-26.c3-0.slvr-ubr1.lnh-slvr.md.cable.rcn.com] has joined #hplusroadmap | 20:08 | |
kanzure | http://openpcr.org/2010/11/igem-2010-synthetic-biology-and-more/ | 20:10 |
-!- Redeemer [~lorddeeme@c-75-72-233-74.hsd1.mn.comcast.net] has quit [] | 20:13 | |
-!- jmil [~jmil@c-76-124-67-155.hsd1.pa.comcast.net] has joined #hplusroadmap | 20:25 | |
-!- egeste_ [~egeste@li147-96.members.linode.com] has joined #hplusroadmap | 21:15 | |
kanzure | hi egeste_ | 21:15 |
-!- hesaid_ [~hesaid@c-1a05e155.15-10-64736c14.cust.bredbandsbolaget.se] has joined #hplusroadmap | 21:16 | |
-!- Noahj1 [~noa@24.38.179.66] has joined #hplusroadmap | 21:16 | |
-!- Netsplit *.net <-> *.split quits: mjr, hesaid, Noahj, egeste | 21:16 | |
-!- Netsplit over, joins: mjr | 21:19 | |
-!- augur [~augur@208-59-167-26.c3-0.slvr-ubr1.lnh-slvr.md.cable.rcn.com] has quit [Remote host closed the connection] | 21:24 | |
-!- jmil [~jmil@c-76-124-67-155.hsd1.pa.comcast.net] has quit [Quit: jmil] | 21:36 | |
-!- phreedom [~quassel@109.254.17.41] has quit [Quit: No Ping reply in 180 seconds.] | 21:41 | |
-!- phreedom [~quassel@109.254.17.41] has joined #hplusroadmap | 21:41 | |
fenn | omfg becoming root on my phone (nexus one) voids the warranty | 21:55 |
-!- augur [~augur@129.2.129.32] has joined #hplusroadmap | 21:56 | |
fenn | so if i want to do something like, oh, wget some mp3's from my server i can't get it repaired when the battery explodes | 21:56 |
-!- augur [~augur@129.2.129.32] has quit [Remote host closed the connection] | 22:09 | |
fenn | https://github.com/martynhaigh/Tiny-Open-Source-Violin | 22:16 |
fenn | seems like there is hardly any open source stuff for android | 22:24 |
superkuh | http://superkuh.ath.cx/violin_slightly-more-tiny-and-slightly-less-opensource.jpg (33kB vs 179kB) | 22:24 |
-!- augur [~augur@208.58.6.161] has joined #hplusroadmap | 22:29 | |
-!- QuantumG [~qg@rtfm.insomnia.org] has joined #hplusroadmap | 23:24 | |
-!- Sneakthief [~Deified@unaffiliated/sneakthief] has joined #hplusroadmap | 23:33 | |
--- Log closed Wed Nov 10 00:00:07 2010 |
Generated by irclog2html.py 2.15.0.dev0 by Marius Gedminas - find it at mg.pov.lt!