2011-01-08.log

--- Log opened Sat Jan 08 00:00:06 2011
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Utopiah(for those against orgmode http://code.google.com/p/vimwiki/ )01:54
Lukas__Good morning02:00
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kanzure"DENDRITES ARE SPROUTING OUT OF MY SKULL!!" http://groups.google.com/group/rec.drugs.smart/browse_thread/thread/62bbf6c304b20cd4#07:18
jennicidei have that problem too07:20
kanzureit's very common07:21
jennicidethere is a guy on one of my networks claiming that he is a cyborg07:22
jennicidei almost directed him here, but thought better of it07:22
kanzuredoes he work on projects or is he just spammy?07:23
jennicideor a third option07:23
jennicidementally unstable07:23
jennicide08:16 Imk0tter • jaytea, there's a good portion of the world, that we refer to as being human07:24
jennicide08:16 Imk0tter • jaytea, and they really arent.. they're androids07:24
jennicideis embedding rare earth magnets into your finger tips still the new hot thing or is that passe by now?07:25
kanzureit's not new at all..07:31
kanzurealso, hi.07:32
jennicideright, so passe07:35
uniqanomalycyborg, hah07:38
uniqanomalyguy needs help07:39
Lukas__heh07:39
Lukas__sounds like07:40
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kanzurehttp://harkopen.com/news/arduino-documentary-2010-english-hd07:51
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kanzurehm designfiles.org is now redirecting to graphsynth.com08:11
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gnushad720328 a long-overdue list of blab equipment useful for do-it-yourself biology08:16
kanzureblab equipment?08:17
kanzureGNUSHA!!!08:17
Lukas__Hello gnusha08:18
gnushaadd60ea a long-overdue list of lab equipment useful for do-it-yourself biology08:19
kanzurethat's better.08:19
Lukas__What sort of lab equipment?08:21
kanzurecheck out revision add60ea to skdb.git08:21
kanzurehttp://diyhpl.us/cgit/skdb/commit/?id=add60eab8a6f3e128476b3ebcdf388e29ede8ae708:22
kanzurehttp://diyhpl.us/cgit/skdb/plain/doc/BOMs/diybio-equipment.yaml08:22
kanzure'glassware' is cheating08:23
Lukas__wtf?  How do you sell a fume hood?08:25
kanzuresell?08:25
Lukas__grr08:25
Lukas__aim conversation08:25
kanzureyou could put a listing up on ebay08:25
Lukas__and this08:25
Lukas__at the same time08:25
Lukas__....08:25
kanzurecraigslist too08:25
Lukas__human brains suck08:25
Lukas__heh, didn't know that was actually possible08:28
kanzureyou might find other things of interest here:08:29
kanzurehttp://diyhpl.us/cgit/skdb/tree/doc/BOMs/08:29
AlonzoTGom?\08:38
kanzureAlonzoTG: do you work with milling machines?08:40
AlonzoTGI had the pleasure of repairing a 20 year old milling machine once,08:40
AlonzoTGbut I don't actually use them...08:40
AlonzoTGNetgear is now on my shitlist.08:51
AlonzoTG=|08:51
AlonzoTG1. my netgear router will loose the ability to serve wireless connections after a few months due to network latency...08:52
AlonzoTG2. When I get a bad sector report on my Ready NAS, I try to go to netgear's site to find out what drives I should put in it, the site is down!!!08:52
AlonzoTGA network services company that can't keep their own network running?? SHEESH!!!08:53
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gnusha56725a9 more diybio-related equipment and greatly improved file organization09:31
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kanzurehi fitzsim09:33
fitzsimhi kanzure09:33
* kanzure was just editing http://diyhpl.us/cgit/skdb/plain/doc/BOMs/diybio-equipment.yaml09:33
kanzureoh you might be a good candidate to review the draft package specification i got fenn to start on yesterday09:34
kanzurehttp://diyhpl.us/cgit/skdb/plain/doc/package_spec.yaml09:34
kanzureesp. from a ne-1, nanotech, or molecular machine perspective09:34
kanzurefenn: in package_spec.yaml under optional->updated, i think you mean pre-commit hook? otherwise you'll be generating spurious commits right?09:38
Lukas__http://www.tasktop.com/videos/mylyn/webcast-mylyn-3.0.html09:39
Lukas__Courtesy of Travisar09:40
kanzurewhat is it? the link isn't very descriptive09:43
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kanzurehi gloop. today's backlog: http://gnusha.org/logs/2011-01-08.log09:49
gloopthanks09:49
gloopKanzure, do you read Glyn Moody?09:50
gloophttps://twitter.com/#!/glynmoody09:50
gloopinteresting source09:50
gloopi'm currently reading about Quora...09:51
kanzureyeah i twitterfollow glyn09:53
kanzurehttp://poeticeconomics.blogspot.com/2011/01/plos-one-now-worlds-largest-journal.html09:53
kanzurehttp://poeticeconomics.blogspot.com/2006/08/dramatic-growth-of-open-access-series.html09:53
kanzuregloop: i used quora to see who in my social network is a super-early adopter09:56
kanzurebased on notifications of when they start to follow me09:56
kanzureresults: http://diyhpl.us/~bryan/irc/followers-quora-ordered09:56
gloopok yeah i read in sfgate09:56
kanzurehuh?09:57
gloopjust the article09:57
gloopi was just referring to the practice09:57
kanzureah, different. the article in sfgate was about http://diyhpl.us/cgit/meetlog/plain/meetlog.txt09:58
kanzurei'm just mentioning the quora thing because it shows adoption rates which might be interesting to someone.09:58
gloopcool, yeah i was curious about that. i'm a bit of an early adopter when i see an interesting use09:59
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gloopfume hoods would benefit from rooms with negative pressure10:09
gloopif i'm not mistaken10:09
gloopsealed doors would be needed10:09
gloopnot that sealed, thought10:10
gloop(reading back in the irc logs of today)10:10
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kanzure"The printed future of Christmas dinner" http://www.bbc.co.uk/news/technology-1206949511:29
kanzurehrm so hod lipson wants everyone to call them 'fabapps'?11:29
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kanzurehi wrldpc211:30
wrldpc2greetings from japan11:31
wrldpc2bryan have you located a torrent or drop for transcendent man anywhere?  I'm kind of shocked it hasn't been leaked yet11:31
kanzureno i haven't found one yet11:31
kanzuremy best guess why is because (1) nobody working for ray knows how to copy it effectively or (2) nobody likes it enough11:32
uniqanomaly"It's outrageous that it has taken two years to release this film. Somebody must see the irony in this, in that this film is about the exponential speed with which technology advances? "11:32
kanzurewrldpc2: on a related note you might like my new year's project: http://diyhpl.us:9000/random11:32
uniqanomalyoh irony11:33
wrldpc2lol11:33
wrldpc2kanz: tight11:33
wrldpc2oh cool11:33
wrldpc2i'll definitely help promote this11:33
kanzureit needs more bug fixes first11:34
kanzureso right now it's just friends11:34
kanzuresuggestions/ideas/bug reports appreciated11:35
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wrldpc2http://www.inventables.com/11:55
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kanzureThe Application Of Business Models To Medical Research: Interviews With Two Founders Of Directed-Philanthropy Foundations http://content.healthaffairs.org/content/26/4/1181.full13:05
kanzureor a transcript from open science summit 2010: http://gnusha.org/transcripts/open-science-summit-2010/scott-johnson-myelin-repair-foundation.html13:05
kanzureoh hm i should use this link for that last one:13:05
kanzurehttp://diyhpl.us/diyhpluswiki/transcripts/open-science-summit-2010/scott-johnson-myelin-repair-foundation/13:05
kanzurehttp://www.myelinrepair.org/research_model/research_process.shtml13:06
kanzuresounds great but i'm a little concerned that their idea of "self-sustaining" is feeding their org off of revenues from patent licensing13:06
kanzureheh..13:16
kanzurehttp://git.spi-inc.org/gitweb/?p=website.git;a=blob_plain;f=meetings/minutes/1998/1998-09-24.mdwn;hb=7cdae9fa30bb1edbbf42236be3099d6eec10622713:16
kanzure"* Consolidate, clarify, and document SPI's relationship with the "Open Source" project and Eric Raymond."13:16
kanzurehmm13:16
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kanzuredidn't know patri runs a blog: http://patrissimo.livejournal.com/13:28
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gnusha8739717 various updates to package_spec.yaml (listed below)14:38
kanzurejrayhawk: is there a way yet to move my http docs root for ikiwiki inside a repository to somewhere other than /?14:38
kanzurei.e. for http://gnusha.org/skdb/14:38
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gnusha178d7c5 we also need a short description for each project14:47
kanzurethough we could just force the first line of 'description' to be at most 140 characters, and just use that for concise descriptions of projects14:47
kanzureso with only 'software' dependencies being mandatory, there's essentially no reason to not use python eggs14:54
kanzureand pip14:55
Lukas__Hello14:58
kanzurehi14:59
Lukas__What insane project have you taken up today?14:59
kanzurejust nitpicking fenn's hardware package format specification http://diyhpl.us/cgit/skdb/plain/doc/package_spec.yaml15:04
kanzurefenn: speaking of which, tim's request was actually for skdb-get.py or something like it to start working again15:04
kanzureoriginally packages were being stored at http://designfiles.org/packages/ but since that's not an option, something on gnusha.org would make sense to me15:04
kanzureformalizing what the client should do or something would be worthwhile15:05
kanzuremy first go at the client from 2008 or 2009 was basically a piece of junk15:05
kanzureputting packages in /usr/share/skdb/ will probably not fly for most users, it should probably be in $HOME or otherwise configured by the user when they install the client15:08
kanzure(put the configuration detail in ~/.skdbconf or whatever)15:09
kanzurethe reason i say that it won't fly is because people don't want these things hidden as far as i can tell15:09
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jrayhawkYeah, you can change srcdir in a later version of piny. I can probably upgrade you later today.16:49
kanzurehooray16:50
Lukas__quick question16:53
Lukas__if you've got a artificial human tissue in the lab, could you stimulate some sort of immune response by introducing a virus?16:54
kanzurewhat tissue?16:55
kanzureyou need blood16:56
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Lukas__...17:00
Lukas__....17:00
Lukas__I am retarded17:00
Lukas__never mind17:00
kanzure*shrug* immune system experiments are still something that go on17:00
kanzurederya unutmaz is a transhumanist in the community who is also a professor of immunology somewhere in new york17:00
kanzureoh wait. microbiology? that doesn't sound right17:00
kanzurehttp://www.med.nyu.edu/microbiology/faculty/unutmaz/17:00
kanzure"Dr. Unutmaz' research focuses on the molecular machinery of T cell activation, differentiation, survival and its explotation by HIV."17:01
kanzuredescription of his research: http://www.med.nyu.edu/microbiology/faculty/unutmaz/unutmaz_res.html17:01
Lukas__O_O17:01
Lukas__thanks17:02
kanzurehe has a few patents related to some cure for HIV17:03
kanzurei think it's held up in FDA limbo17:03
Lukas__The17:03
Lukas__freakin' FDA17:04
kanzurefascist death administration17:04
kanzurefucking death administration17:04
kanzurefederal death administration17:04
kanzureetc.17:04
Lukas__The were necessary back in the day, but now it's really, really bloated17:06
Lukas__anyway17:06
kanzurei do think due diligence on drugs is a good idea, though not for people who are at the end of the road17:06
Lukas__I wanted to test gene therapy vectors on tissue samples to see if there was a) an immune response and if b) the protein was expressed (and the emergent properties)  - looks like I'll have to re-plan17:07
kanzurewhy not work on the mouse model?17:08
kanzureit's been extensively tested in genetic engineering17:08
Lukas__My main worry is protein-protein interaction that may cause shit to go wrong - we already have clever ways of getting past the immune system, now can we make sure a protein won't do something it isn't supposed to do17:10
Lukas__mice are excellent models17:11
Lukas__but a handful of chemicals can makes things go terribly wrong17:11
Lukas__so I wanted something as close to home as possible17:11
AlonzoTGRetrovirus?17:19
AlonzoTGI don't think those will ever work.17:19
AlonzoTGThe procedure that will work is to extract a cell, sequence the chromasome you want,17:19
AlonzoTGedit it in vi (urk, don't ever use vi for anything!), synthesize the new chormasome, re-build the cell, culture it, and then re-introduce it to the organism.17:20
kanzurewhat the hell is a chromasome17:20
kanzureLukas__: you should look into lentiviruses17:20
AlonzoTGdunno; can't spell.17:20
AlonzoTGU have 48 of them though.17:20
Lukas__AlonzoTG, I had an idea about that17:21
Lukas__using stem cells to create new cell lines17:21
Lukas__but the issue is still the same17:21
Lukas__the body will reject it17:21
kanzurenot always17:21
Lukas__...17:21
Lukas__what now?17:21
Lukas__what do you mean?17:21
AlonzoTGReally? It shouldn't, the genetics would be 99% compatible.17:21
Lukas__1% is the problem17:22
Lukas__whatever new protein it expresses will be tagged17:22
Lukas__and destroyed17:22
AlonzoTGHow can an immune system be THAT sensitive?17:22
AlonzoTGThere have to be protene structures that it will permit.17:22
kanzurealso, you're talking about surface proteins17:23
AlonzoTGYeah, that could be a problem. =(17:24
kanzureproteins inside the cell are not going to be finding their way into an antibody17:24
Lukas__The immune system is a pain in the ass, and <kanzure> I still trying to figure out where the proteins will be with what I want to do17:25
Lukas__but good point17:25
kanzureLukas__: you should read an article from the journal called "annual reviews" about genetic engineering of mice17:25
kanzurei'm sure they have lots of reviews on genetic engineering by now17:25
Lukas__alright, thanks17:25
Lukas__wait a minute17:29
Lukas__what happens when the cell dies?17:29
Lukas__Wait, no, it doesn't undergo lysis17:41
Lukas__which means this should work17:41
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Lukas__I am checking out for the night18:08
kanzuregood night18:08
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kanzurebugs everywhere just hit 1.0.0 a few minutes ago http://gitorious.org/be18:09
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kanzurebaidu is crawling hplusvideo19:21
kanzurecraig venter at space manufacturing 14 http://diyhpl.us:9000/s/craig-venter-synthetic-genomics19:31
kanzuresuperkuh: ustream and others work now19:31
superkuhCool, thanks.19:32
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kanzuresilly unicode errors20:08
kanzurespace manufacturing 14 is up20:10
kanzureopen science summit 2010 is up20:10
kanzurehttp://diyhpl.us:9000/s/session-4-1-robotics-and-space-manufacturing-mitchell-weiss20:10
kanzurehttp://diyhpl.us:9000/s/session-4-2-robotics-and-space-manufacturing-greg-baiden20:10
kanzurehttp://diyhpl.us:9000/s/prof-john-lewis-asia-s-road-to-the-moon20:10
kanzurehttp://diyhpl.us:9000/s/prof-john-lewis-asia-s-road-to-the-moon-part-220:10
kanzurehttp://diyhpl.us:9000/s/session-5-1-engineering-materials-from-non-terrestrial-resources20:11
kanzurehttp://diyhpl.us:9000/s/session-5-2-in-situ-production-of-construction-materials20:11
kanzurehttp://diyhpl.us:9000/s/session-7-international-legal-and-economic-considerations20:11
kanzurehttp://diyhpl.us:9000/s/session-7-international-legal-and-economic-considerations-ccdc820:11
kanzurenow for open science summit 2010 highlights:20:11
kanzurehttp://diyhpl.us:9000/s/the-role-of-universities-in-the-knowledge-economy20:11
kanzurehttp://diyhpl.us:9000/s/alan-bennett-and-keith-bergelt-patent-pools20:11
kanzurehttp://diyhpl.us:9000/s/bunin-hessel-izant-open-source-drug-discovery20:11
kanzurehttp://diyhpl.us:9000/s/baber-benson-johnson-cure-entrepreneurs20:12
kanzurehttp://diyhpl.us:9000/s/alternative-funding-mechanisms-for-science-r-d20:12
kanzurehttp://diyhpl.us:9000/s/safety-and-security-concerns-open-source-biodefense20:12
kanzurehttp://diyhpl.us:9000/s/microfinance-crowd-funding-for-science20:12
kanzurehttp://diyhpl.us:9000/s/epistemology-2-0-the-future-of-online-science20:12
kanzurehttp://diyhpl.us:9000/s/introduction-to-open-access-and-latest-developments20:12
kanzurehttp://diyhpl.us:9000/s/gene-patents-moving-beyond-the-myriad-fallout20:12
kanzurehttp://diyhpl.us:9000/s/human-genome-project-and-synthetic-biology20:12
kanzurehttp://diyhpl.us:9000/s/citizen-science-in-biology20:12
kanzurehttp://diyhpl.us:9000/s/mike-gretes-neglected-disease-r-d20:12
kanzurehttp://diyhpl.us:9000/s/josh-perfetto-openpcr20:12
kanzurehttp://diyhpl.us:9000/s/james-peyer-otyp20:12
kanzurehttp://diyhpl.us:9000/s/todd-kuiken-responsible-science-for-diy-biologists20:12
kanzurethat should be enough for now :)20:13
kanzuresingularity summit videos20:47
kanzurehttp://diyhpl.us:9000/s/anders-sandberg-at-singularity-summit-2009-technical-roadmap-for-whole-brain-emulation20:47
kanzurehttp://diyhpl.us:9000/s/randal-koene-at-singularity-summit-2009-the-time-is-now-as-a-species-and-as-individuals-we-need-whole-brain-emulation20:47
kanzurehttp://diyhpl.us:9000/s/ed-boyden-at-singularity-summit-2009-synthetic-neurobiology-optically-engineering-the-brain-to-augment-its-function20:47
kanzurehttp://diyhpl.us:9000/s/william-dickens-at-singularity-summit-2009-cognitive-ability-past-and-future-enhancements-and-implications20:48
kanzurehttp://diyhpl.us:9000/s/ray-kurzweil-at-singularity-summit-2009-the-ubiquity-and-predictability-of-the-exponential-growth-of-information-technology20:48
kanzurehttp://diyhpl.us:9000/s/bela-nagy-at-singularity-summit-2009-more-than-moore-comparing-forecasts-of-technological-progress20:48
kanzure"more than moore.. you could say.. max more?" ouch20:48
kanzurehttp://diyhpl.us:9000/s/gregory-benford-at-singularity-summit-2009-artificial-biological-selection-for-longevity20:48
kanzurehttp://diyhpl.us:9000/s/gary-marcus-at-singularity-summit-2009-the-fallibility-and-improvability-of-the-human-mind20:48
kanzurehttp://diyhpl.us:9000/s/peter-thiel-at-singularity-summit-2009-macroeconomics-and-singularity20:48
kanzurehttp://diyhpl.us:9000/s/aubrey-de-grey-at-singularity-summit-2009-the-singularity-and-the-methuselarity-similarities-and-differences20:48
kanzurehttp://diyhpl.us:9000/s/anna-salamon-s-2nd-talk-at-singularity-summit-how-much-it-matters-to-know-what-matters-a-back-of-the-envelope-calculation20:49
kanzurehttp://diyhpl.us:9000/s/venture-capitalist-panel-at-singularity-summit-200920:49
kanzurehttp://diyhpl.us:9000/s/sejnowski-bray-debate-will-we-soon-realistically-emulate-biological-systems-20:49
kanzurehttp://diyhpl.us:9000/s/gregory-stock-evolution-of-post-human-intelligence20:49
kanzurehttp://diyhpl.us:9000/s/dennis-bray-what-cells-can-do-that-robots-can-t20:49
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--- Log closed Sun Jan 09 00:00:04 2011

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