| --- Log opened Wed Aug 10 00:00:18 2011 | ||
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| fenn | different jonathan stark | 03:06 |
|---|---|---|
| fenn | man, cleaning out a commit from multiple repositories is quite a pain | 03:07 |
| fenn | there's no "git delete-this-commit-yes-im-sure" command | 03:08 |
| fenn | instead you have to do a bunch of resets and make a new branch and merge your new branch back in | 03:08 |
| fenn | or at least that's how i did it.. | 03:09 |
| fenn | chemical of the day: zeaxanthine | 03:10 |
| fenn | er, zeaxanthin | 03:10 |
| fenn | http://www.zeavision.com/research.html | 03:12 |
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| kanzure | hmm | 05:28 |
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| archels | http://www.kurzweilai.net/first-direct-biological-evidence-found-for-genetic-contribution-to-intelligence | 06:25 |
| archels | what manner of bullshit is this, 'the *first* study to link genetics to intelligence' | 06:25 |
| kanzure | it's kurzweil bullshit! | 06:40 |
| kanzure | actually thomas mccabe probably wrote that one | 06:40 |
| kanzure | or amara | 06:40 |
| archels | heh yeah | 06:47 |
| kanzure | saurik: what about this 4g man-in-the-middle attack.. does anyone have it available for download/analysis? | 07:09 |
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| JayDugger | Good morning, everyone. | 07:58 |
| kanzure | hi JayDugger | 08:01 |
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| Lucas__ | http://www.youtube.com/watch?v=kRDg4UB9Ajg&feature=feedu | 08:08 |
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| Lucas__ | First flight of 3D printed plane | 08:08 |
| Juul | link? | 08:11 |
| archels | damn, that lady's voiceover gives me goosebumps. | 08:11 |
| Lucas__ | xD | 08:12 |
| archels | Juul, logs link is in topic. | 08:12 |
| archels | (teach a man how to fish, etc.) | 08:12 |
| Juul | :) | 08:12 |
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| Lucas__ | Kanzure is going to Vietnam? | 08:39 |
| kanzure | Cộng hòa xã hội chủ nghĩa Việt Nam | 08:39 |
| Lucas__ | "Socialist Republic of Vietnam" *looks at Google* "thanks" | 08:41 |
| Lucas__ | Kanzure, you need to slap some sense into these "transhumanist groups" | 08:45 |
| Lucas__ | ALL THEY DO IS TALK ABOUT USELESS SHIT | 08:46 |
| kanzure | who are you hanging out with now? | 08:47 |
| Lucas__ | I am still a part of those facebook groups | 08:48 |
| Lucas__ | um | 08:48 |
| Lucas__ | hold on | 08:48 |
| Lucas__ | "Human 2.0" or some such shit | 08:49 |
| Lucas__ | //facedesk | 08:49 |
| Lucas__ | the only people actually doing something is biohack.me and kanzure's legion | 08:49 |
| Lucas__ | I mean hplusroadmap | 08:49 |
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| delinquentme | FPGA vrs GPU within bio computation.. anyone? | 11:23 |
| kanzure | depends on what type of algorithm you're running | 11:25 |
| delinquentme | as to which is faster huh | 11:32 |
| delinquentme | have you programmed FPGAs? | 11:32 |
| kanzure | a long time ago | 11:35 |
| delinquentme | how about a minimum page length on scientific papers | 11:36 |
| delinquentme | and do you know anything about the clevage methods on dna sequencers | 11:36 |
| delinquentme | these have been taunting me ... i SHALL SEARCHETH | 11:37 |
| kanzure | they are usually acid washes of some sort | 11:37 |
| delinquentme | hmm ill read more about it | 11:37 |
| delinquentme | oh! | 11:37 |
| delinquentme | but so im reading these bioinf books .. and they're talking about the algos | 11:37 |
| kanzure | alignment? | 11:38 |
| delinquentme | more and more as seq tech gets to longer and longer reads .. theyre going to be used less and less | 11:38 |
| delinquentme | correct | 11:38 |
| delinquentme | so i just wanted to see if you mirrored that sentiment | 11:38 |
| delinquentme | perhapse alignment algos arent the best place to invest time / learning | 11:38 |
| kanzure | nope you will need to do alignment for the forseeable future | 11:38 |
| kanzure | for at least the next three years maybe | 11:39 |
| kanzure | there might be some sequencing technology that can do direct reads of entire genomes but i doubt it | 11:39 |
| kanzure | and you will still need to confirm that the data is accurate and in the right order | 11:39 |
| kanzure | *but i doubt it will work in the next three years on the market to the extent that it effects you | 11:40 |
| kanzure | *that it would effect you | 11:40 |
| delinquentme | ok well lets assume that it does | 11:40 |
| delinquentme | what happens next | 11:40 |
| kanzure | what are you assuming specifically? | 11:40 |
| delinquentme | lets say we've got read lengths in the 10 thousands | 11:41 |
| kanzure | 100% accurate single reads of genomes? | 11:41 |
| delinquentme | sure | 11:41 |
| kanzure | even with 10k bp read length you still need to assemble the fragments dude.. | 11:41 |
| kanzure | s/assemble/align | 11:41 |
| delinquentme | that works .. so then ... perhapse cross comparisons of tons and tons of genomes? | 11:41 |
| kanzure | if you want | 11:41 |
| delinquentme | efficient search code within the read data? | 11:41 |
| kanzure | which is what blast does | 11:41 |
| delinquentme | yeahhh but computation on 10k base pair length is going to be substantially quicker / simpler | 11:42 |
| delinquentme | yeah i read a little bit about blast | 11:42 |
| kanzure | not necessarily, you still have to check if there's homology since different codons still match up to the same amino acids | 11:42 |
| kanzure | anyway it's already quite common to run blast on segments of 10k bp | 11:42 |
| delinquentme | O_o ? | 11:43 |
| kanzure | most proteins that are interesting to us are 1k-100k bp in size | 11:43 |
| delinquentme | ohh ok you're talking searching .. not assembling 10k length reads | 11:44 |
| kanzure | delinquentme: have you seen this little project of mine? http://diyhpl.us:9000/random | 11:44 |
| kanzure | i'm talking searching and alignment | 11:44 |
| delinquentme | i saw the videos you had been collecting | 11:45 |
| kanzure | there's a number of bioinformatics tutorials on there | 11:45 |
| kanzure | but iirc it's basic stuff like blast, real time blast, other blast algorithms | 11:45 |
| kanzure | phlyogenetic comparison shit.. etc. | 11:45 |
| delinquentme | yeah the ebook i've got does some comparisons | 11:46 |
| delinquentme | "k-mers" | 11:47 |
| delinquentme | BLOSUM matrices | 11:47 |
| delinquentme | the ways that they search for high probability then build the rest about those | 11:47 |
| delinquentme | very much so its an information science .. but once the hardware catches up | 11:47 |
| delinquentme | but you're saying you dont see that happening within the next 4 years | 11:48 |
| kanzure | what? | 11:48 |
| kanzure | where the hell did i say that? | 11:48 |
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| kanzure | all i said is that you will probably still have to do alignment on genomic data from sequencing for at least another three years | 11:48 |
| delinquentme | now these videos | 11:50 |
| delinquentme | these all have to do with LE specifically orrr? | 11:50 |
| kanzure | lots of them are about life extension | 11:55 |
| kanzure | but the general theme is human enhancement, transhumanism, biohacking, microfluidics, synthetic biology | 11:56 |
| kanzure | open hardware | 11:56 |
| kanzure | stuff like that. | 11:56 |
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| archels | http://web.mit.edu/newsoffice/2011/antiviral-0810.html | 12:56 |
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| kanzure | archels: what is that? | 13:10 |
| kanzure | oh i'm not gonna click that it's probably the lincoln lab stuff | 13:10 |
| archels | Rider had the idea to combine a dsRNA-binding protein with another protein that induces cells to undergo apoptosis (programmed cell suicide) — launched, for example, when a cell determines it is en route to becoming cancerous. Therefore, when one end of the DRACO binds to dsRNA, it signals the other end of the DRACO to initiate cell suicide. | 13:26 |
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| Juul | does anyone know how you pronounce "Cathal" in "Cathal Garvey"? | 13:32 |
| Juul | Katal? or like the th in Cathy? | 13:32 |
| Juul | or Cartarl? | 13:32 |
| fenn | cool blog about self improvement and unconventional life strategies http://www.ajkesslerblog.com/new-start-here/ | 13:35 |
| fenn | "The Tyler Durden Self Help Method" | 13:39 |
| Juul | tough self-love? | 13:41 |
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| archels | kanzure: Any opinion on the above? | 13:43 |
| kanzure | archels: not really :) | 13:49 |
| fenn | “Everyone believes an experiment except the experimenter; no one believes a theory except the theorist.” | 14:04 |
| kanzure | if the experimenter doesn't believe his experiment will be useful then why the hell is he doing it | 14:09 |
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| kanzure | australia national radio has a piece on biohackers | 15:30 |
| kanzure | http://www.abc.net.au/rn/futuretense/stories/2011/3285426.htm | 15:30 |
| kanzure | er, i think | 15:30 |
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| Technicus | Hello . . . | 15:53 |
| kanzure | hi Technicus | 16:04 |
| Technicus | :] | 16:06 |
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| kanzure | heh a brain pathologist posted about his home setup | 16:41 |
| kanzure | https://groups.google.com/forum/#!topic/diybio/KyQzqEAfWpA | 16:41 |
| kanzure | oops i meant http://groups.google.com/group/diybio/t/2b2433a8401f5a90 | 16:41 |
| delinquentme | kanzure, thoughts on this HN post about coffee and cannabinoids? | 16:51 |
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| meefs | endocannabinoids, couldn't live without them | 17:19 |
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| eudoxia | guysguysguys | 19:11 |
| kanzure | OMG WHATT?! | 19:11 |
| eudoxia | a bunch of luddites bombed a nanotechnology lab | 19:11 |
| kanzure | ooh ooh | 19:11 |
| kanzure | show me show me | 19:11 |
| eudoxia | http://yro.slashdot.org/story/11/08/10/2349225/Terrorist-Target-Mexican-Nanotechnology-Professors | 19:12 |
| kanzure | http://blog.ketyov.com/2011/08/self-stimulating-brain-for-heterosexual.html | 19:12 |
| kanzure | eudoxia: fun times | 19:12 |
| kanzure | eudoxia: they seem more efficient than siai | 19:13 |
| fenn | "keep nanotech out of mexico" is the message? okay, done. | 19:17 |
| fenn | wow, i'm having a hard time believing this | 19:19 |
| uniqanomaly | http://en.wikipedia.org/wiki/False_flag | 19:19 |
| uniqanomaly | simple as that | 19:19 |
| fenn | what does that mean? | 19:20 |
| fenn | americans killed some mexican professor? | 19:20 |
| uniqanomaly | why would they do such a horrible thing? | 19:21 |
| eudoxia | it's a Deus Ex HR viral | 19:28 |
| kanzure | evidence? | 19:30 |
| kanzure | i don't like all this anti-human-augmetation shit they are pumping out | 19:31 |
| kanzure | where do they live so i can go kill them? | 19:31 |
| eudoxia | well it sort of goes from 'fuck yeah transhumanism' to 'the gov'ment and big pharma is trying to enslave us ALL' | 19:33 |
| eudoxia | i wouldn't kill them just yet | 19:33 |
| kanzure | "big pharma" is just a concept.. if you really care that much about your drugs make them yourself | 19:34 |
| QuantumG | is there a little pharma? | 19:43 |
| evolv | QuantumG, yeah, the local weed dealer | 19:44 |
| evolv | little pharma? cool | 19:44 |
| evolv | big pharma? Bad | 19:44 |
| QuantumG | that's what I had in mind too | 19:46 |
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| kanzure | little pharma is the guy standing out by the corner with gangrene | 19:47 |
| uniqanomaly | "If this turned out to be a viral marketing campaign, WTF @ real bombs" lol | 19:50 |
| uniqanomaly | http://www.neogaf.com/forum/showthread.php?t=440312 | 19:50 |
| kanzure | fenn: they sent me their crawlers | 20:11 |
| kanzure | it's a 50kb zip file | 20:11 |
| fenn | okay. | 20:12 |
| fenn | does this mean i should deliver the nda thingy/ i'm too busy to work on it for a month anyway | 20:13 |
| fenn | also, bbl | 20:13 |
| kanzure | oh hey it's a legit perl module | 20:14 |
| kanzure | this isn't that bad | 20:14 |
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| saurik | kanzure: I probably know less about the 4G man-in-the-middle than you do at this point (all I read about it is the conversation on hacker news) | 23:54 |
| --- Log closed Thu Aug 11 00:00:19 2011 | ||
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