--- Log opened Wed Oct 26 00:00:13 2011 | ||
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fenn | so if i take steroids i'll be able to lift 15% more weight than i could without them? wow. | 07:02 |
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kanzure | are you being sarcastic? | 07:04 |
fenn | yes | 07:05 |
kanzure | has anyone done a study about running performance? | 07:05 |
fenn | i'm sure, why? | 07:06 |
kanzure | "i'll be able to escape a bear 15% faster" | 07:06 |
fenn | but i just need to be faster than you... | 07:06 |
fenn | it's too bad there's not actually an "all-drug olympics" | 07:07 |
kanzure | why not make it? | 07:07 |
kanzure | besides the various laws | 07:07 |
fenn | um, the laws are a big part | 07:07 |
fenn | personally, i think sports are a waste of time | 07:08 |
kanzure | BAH | 07:08 |
kanzure | bah to the laws, i mean | 07:08 |
fenn | first ever all-drug typing competition! held in monaco | 07:08 |
kanzure | 'anabolic steroid control act of 1990' damn, had to be my year.. | 07:09 |
kanzure | "The Anabolic Steroid Control Act of 2004 - placed 32 additional steroids in Schedule III and expanded DEA’s regulatory and enforcement authority regarding steroids." | 07:09 |
fenn | you know you can still take testosterone in various forms | 07:09 |
kanzure | "The University of Michigan’s 2004 “Monitoring the Future” Study reported 3.4% of 12th graders having used steroids at least once." | 07:09 |
fenn | i have a bottle of tribulus right here | 07:09 |
kanzure | of course.. there's lots of medical uses too | 07:09 |
kanzure | "A Center for Disease Control and Prevention’s 2003 survey of U.S. high school students found that 6.1% reported having abused steroids, showing a 10-year increasing trend" | 07:10 |
fenn | i dont know why anyone would take an anabolic steroid besides testosterone | 07:10 |
kanzure | let's ask our friends at bodybuilding.com | 07:10 |
kanzure | what i really want to know is why transhumanists are really really against steroids in general | 07:11 |
fenn | negative publicity via association | 07:11 |
kanzure | maybe it's the same reason they hate anti-aging creams, but they both serve a purpose | 07:11 |
fenn | question of definitions: are bodybuilders transhumanists? | 07:12 |
kanzure | haha negative publicity.. yeah, big fucking deal- wait 'til stem cells OH WAIT | 07:12 |
kanzure | hmm | 07:12 |
fenn | i would say no because it's sort of a meme complex rather than a particular belief | 07:13 |
kanzure | maybe; there's definitely some sort of meta-control-feedback stuff going on? | 07:13 |
fenn | i.e. why is space exploration lumped in there with transhumanist ideas? | 07:13 |
kanzure | is it? it's just sorta assumed that any transhumanist megabrain would prefer to use the local star for energy right? | 07:14 |
kanzure | i'm being dense | 07:15 |
fenn | so, noopept is quite nice | 07:15 |
kanzure | i wonder if asking "is x transhumanist" a useful question | 07:15 |
kanzure | "but is up to 1000 times more potent than the prototypical racetam drug, piracetam." | 07:16 |
kanzure | "is a medication promoted and prescribed in Russia" damn russians! | 07:16 |
fenn | i can't say that it exploded my universe or anything, but it's definitely more noticeable than piracetam | 07:16 |
kanzure | you seem to be taking lots of alzheimer's drugs | 07:16 |
fenn | i mean it didn't have a noticeable "i feel smarter" effect | 07:16 |
fenn | i remember pulling some gross dishes out of a sink and not being annoyed at all | 07:17 |
kanzure | god damn it grandma is sending me steve jobs love letters | 07:17 |
kanzure | hey so about the site that i'm presumably making, | 07:19 |
kanzure | i can't figure out if it's a search engine or a social app or what | 07:19 |
kanzure | price comparison is very much like a search engine | 07:19 |
fenn | "i feel very coordinated and in control of my thoughts and movements. quiet, observant." | 07:19 |
fenn | i was thinking more or less like octopart | 07:20 |
kanzure | i think the regimen sharing feature is critical | 07:20 |
kanzure | so that would be like BOMs being added to octopart? | 07:21 |
fenn | parametric search, "nesting" or optimizing ordering from different suppliers | 07:21 |
fenn | BOM does what on octopart? | 07:21 |
kanzure | there are no BOMs on octopart | 07:22 |
fenn | i dont see what regimen sharing has to do with a search engine | 07:22 |
kanzure | exactly that's why i'm a wee bit confused | 07:22 |
kanzure | should it be a separate site? | 07:22 |
fenn | maybe you also want some kind of forum with integration to the search engine somehow | 07:22 |
kanzure | not really | 07:22 |
kanzure | NO TALKING | 07:22 |
fenn | hey it was my idea in the first place | 07:22 |
kanzure | maybe the "shopping cart" could be saved as a regimen | 07:23 |
fenn | so, it should have a nice restful API and then people can add whatever forums they like | 07:23 |
kanzure | well, i'd prefer an api/platform for integrating tests or experiments that people participate in | 07:24 |
fenn | automatic ordering is going to be hard | 07:24 |
kanzure | but that's very much in the realm of genomera and seems lame to me | 07:24 |
fenn | it's much easier to "fake" scraping for messed up sites than to fake automatic ordering | 07:24 |
kanzure | true | 07:24 |
kanzure | automatic ordering is down the pipeline i wouldn't worry about it right now | 07:25 |
fenn | i like the idea of performance testing of interventions | 07:25 |
fenn | genomera is | 07:25 |
kanzure | are you agreeing that genomera is lame | 07:25 |
fenn | genomera is lame because they do lame experiments that don't really answer any questions | 07:25 |
kanzure | BUTTER! | 07:25 |
kanzure | lots of it | 07:25 |
fenn | and they send me lots of email about crap i don't care about | 07:25 |
fenn | "so and so made a change, click here to see what they did!" | 07:26 |
fenn | wow they changed their status to experimenter! amazing~ | 07:26 |
kanzure | what sort of parametric searching would make you happ[y? | 07:27 |
kanzure | happy? | 07:27 |
fenn | well, i'd like to search by price per dose, price per mg, price of minimum package size... | 07:27 |
kanzure | there's also the issue of generic drug/structure versus actual products | 07:27 |
fenn | then each supplement might have its own characteristics, like "cold pressed" might not apply to every supplement, only fatty acid stuffs | 07:28 |
fenn | yes, for example merck(?) has the patent on time released adderall | 07:28 |
kanzure | shire | 07:28 |
kanzure | but it went generic i thought? | 07:28 |
fenn | dunno | 07:28 |
kanzure | it did.. i have multiple adderall xr pills here by different manufacturers now | 07:29 |
kanzure | (and they all do fucking different things, argh) | 07:29 |
fenn | hm? | 07:29 |
fenn | they're not the same thing? or they claim to be the same but have different effects? | 07:29 |
kanzure | i think the release mechanisms are different between the manufacturers | 07:29 |
fenn | there's a lot of fluff out there, like "super bio-sorb coq10 with hydroxylated soybean oil!" | 07:30 |
fenn | so | 07:30 |
fenn | supposedly you can take 300mg of coq10 or 100mg with super bio-sorb and get the same effect | 07:31 |
fenn | but should we believe them? | 07:31 |
fenn | i kind of hate that technology has politics, but if i have a zillion choices nobody will want to use the service | 07:31 |
kanzure | i am thinking it should be a giant search engine and you list what you want, then it helps you narrow it down | 07:32 |
kanzure | *giant search box | 07:32 |
kanzure | and it returns results from products, regiments, or other results plus parameters to help you narrow down the search | 07:32 |
kanzure | then at the end it lists out where to buy the shit and possible experiments to join | 07:32 |
fenn | ok but do i multiply the value of super bio-sorb by 3? or not? | 07:32 |
fenn | can you compare apples and oranges? | 07:33 |
kanzure | what i suspect is happening is that people are finding local maxima for themselves of drugs that seem to work for them | 07:33 |
kanzure | this isn't necessarily an optimal cocktail of supplements | 07:33 |
fenn | of course | 07:33 |
fenn | there are also time-variant effects | 07:34 |
fenn | and state dependent effects | 07:34 |
fenn | i.e. DMAE may not help at all if you've already been taking it for a couple months | 07:35 |
fenn | but that doesn't mean it isn't worth taking at all | 07:35 |
kanzure | hm, it would be nice to get a history of supplement use too | 07:35 |
fenn | i think what you're going after is going to be a more hands-on project | 07:36 |
fenn | i was going to do it as part of cyborg camp | 07:36 |
kanzure | what is "more hands-on"? | 07:36 |
fenn | basically as part of the borg you sign your body away and each person does their own experiment and is tracked rigorously in all aspects of life | 07:36 |
fenn | wearable biosensors and computer integration, random cognitive performance testing and mood metrics | 07:37 |
kanzure | i'm not sure if it's possible or useful to do combinatorial testing across all drugs for a single person across all timing possibilities | 07:38 |
fenn | no, you have to do singular value decomposition | 07:38 |
fenn | it's sort of like measuring the length of a table | 07:38 |
fenn | hm, bad analogy | 07:38 |
fenn | it's sort of like measuring the position of a proton | 07:39 |
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fenn | by bouncing a photon off it, you alter the velocity vector of the proton | 07:40 |
kanzure | humn=proton? | 07:40 |
kanzure | human | 07:40 |
fenn | but with enough samples you can derive some laws about how protons and photons interact | 07:41 |
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fenn | that's all we're trying to do | 07:41 |
kanzure | maybe it would be useful to focus specifically on drugs that make up for differences in genotypes/snps? | 07:41 |
fenn | then once you have all your expected effects measured, you just do monte carlo optimization or whatever | 07:41 |
kanzure | ok | 07:42 |
fenn | why focus on the differences when you can focus on the similarities? | 07:42 |
fenn | the goal is to be absolutely better, not relatively better | 07:42 |
fenn | people have been fighting for too long already | 07:43 |
kanzure | how is that people don't understand how bad patents are? it's called "royalties" for a reason! | 07:49 |
kanzure | bleh | 07:49 |
kanzure | ooh https://github.com/danchoi/fredit | 07:50 |
kanzure | http://blog.wekeroad.com/2011/10/25/the-hubble-blew-my-mind | 07:52 |
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kanzure | http://breakoutlabs.org/ is up finally | 08:45 |
kanzure | it's peter thiel's.. thing.. for science.. things | 08:45 |
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ory_web | hi | 08:52 |
ory_web | i have problem whith ideneb | 08:52 |
ory_web | :( | 08:53 |
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kanzure | upverter.com looks broken | 09:19 |
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kanzure | http://www.sciencenews.org/view/generic/id/335541/title/Gene_makes_some_pilots_get_rusty_faster | 10:14 |
kanzure | the gene is bdnf | 10:14 |
eudoxia | is peter thiel an inexhaustible source of monies for transhumanism? | 10:19 |
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archels | kanzure: mmm, neurogenesis-related? | 10:46 |
kanzure | haven't checked | 10:48 |
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kanzure | "One situation where I do not need help, let alone supervision, is in crossing streets. I grew up in the middle of the world's biggest city, full of cars, and I have crossed streets without assistance even in the chaotic traffic of Bangalore and Delhi. Please just leave me alone when I cross streets." | 11:10 |
kanzure | poor stallman | 11:11 |
archels | wat | 11:43 |
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yottabit | hrm | 12:33 |
yottabit | why is gnusha.org inaccesible but ybit is still online? | 12:33 |
yottabit | jrayhawk! | 12:33 |
yottabit | or JayDugger! | 12:33 |
yottabit | i forget which one of the J's it was that created an account for me :) | 12:33 |
kanzure | jrayhawk | 12:34 |
kanzure | diyhpl.us is the same server fyi | 12:34 |
kanzure | or bryan.svcs.pdx.edu or something | 12:34 |
* yottabit was about to grep the logs, but that works | 12:34 | |
jrayhawk | the nameservers for gnusha appear to be having issues | 13:02 |
kanzure | oh right i never taught myself proper dns management | 13:02 |
kanzure | i guess that's sorta important huh | 13:02 |
jrayhawk | would you like me to provide a bind setup on gnusha.org and somewhere else for you to play with | 13:07 |
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kanzure | jrayhawk: that would be fine | 13:13 |
kanzure | also if you could beat me over the head with bind documentation that would help too | 13:14 |
jrayhawk | eh, not really a worthwhile plan, there. half the stuff bind claims to have support for is a lie. | 13:15 |
jrayhawk | there's only a few workflows you really want to worry about | 13:15 |
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kanzure | infomorph==SDr? | 13:48 |
SDr | infomorph ⊂ SDr | 13:59 |
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* SDr sometimes acts as an instrument for minority reports ^^ | 14:00 | |
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kanzure | http://royalsociety.org/news/Royal-Society-journal-archive-made-permanently-free-to-access/ | 17:24 |
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kanzure | discussion: http://news.ycombinator.com/item?id=3158061 | 17:24 |
klafka | good | 17:24 |
klafka | now if only jstor followed | 17:25 |
yottabit | who's the guy wanting to do OSE stuff in arizona again, and when is gnusha coming back online? | 17:28 |
jrayhawk | The server itself is not offline; you can ssh to 131.252.130.248 | 17:33 |
jrayhawk | I suspect gkg.net is experiencing a DoS or something. | 17:33 |
JayDugger | Good evening, everyone. | 18:03 |
jrayhawk | for future reference, if you aren't using HashKnownHosts, you can look up the addresses of servers you've previously sshed to in .ssh/known_hosts | 18:03 |
JayDugger | fenn, kanzure: space exploration gets "lumped in" with transhumanist ideas because of Dandrige Cole's work in the early 1960s for General Electric. | 18:07 |
JayDugger | Supposedly he'd read Ettinger's The Prospect of Immortality, but his family buried him after a fatal heart attack at 44. | 18:13 |
JayDugger | Cole marks the earliest overlap I know about, but others might predate even him. | 18:16 |
kanzure | jrayhawk: i actually use freedns.afraid.something | 18:18 |
jrayhawk | for heybryan, yeah | 18:19 |
jrayhawk | note that that one is actually working | 18:19 |
jrayhawk | for i in diyhpl.us gnusha.org; do whois $i | grep -i 'Name Server'; done | 18:19 |
JayDugger | Thanks for the tip about HashKnownHosts, jrayhawk. | 18:21 |
jrayhawk | I really wish known_hosts were indexed by key :( | 18:22 |
kanzure | BAH whatever | 18:27 |
JayDugger | Evocative, but vague. | 18:28 |
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JayDugger | Good night, everyone. | 19:07 |
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kanzure | "We once had a guy do PCP in the bathroom during a tattoo break. He came out and resumed getting tattooed, | 20:25 |
kanzure | and minutes later, was screaming at the top of his lungs about the incredible power in his body. He stood up and carried a 400 lb. barber's chair out the front door, put it in traffic, disrobed and sat in it. | 20:25 |
yottabit | HashKnownHosts, thanks jrayhawk | 20:25 |
kanzure | He sat there, screaming in traffic, nude in a barber chair, until the police arrived." | 20:25 |
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jrayhawk | haha | 20:49 |
kanzure | what's worse is that i accidentally pasted that to a client of mine | 20:50 |
kanzure | instead of the instructions for logging into his admin panel | 20:50 |
kanzure | fuck | 20:50 |
kanzure | but it was only the last 50% | 20:50 |
jrayhawk | professionalism | 20:52 |
kanzure | yup | 20:55 |
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