2011-11-07.log

--- Log opened Mon Nov 07 00:00:31 2011
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antipragmatisthi05:32
antipragmatisthi kanzure05:32
antipragmatistkanzure, do you know anything about micrometer construction?05:33
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-!- Topic for ##hplusroadmap: http://gnusha.org/skdb/ http://groups.google.com/group/diybio http://bit.ly/diybionews http://gitduino.com/ http://gadaprize.org/ | logs: http://gnusha.org/logs/06:19
-!- Topic set by kanzure [~kanzure@131.252.130.248] [Thu Jan 20 10:44:20 2011]06:19
[Users ##hplusroadmap]06:19
[ AlonzoTG] [ drazak ] [ foucist ] [ marainein ] [ saurik ] [ wrldpc] 06:19
[ augur ] [ elmom ] [ gedankenstuecke] [ Mariu ] [ splicer ] [ ybit ] 06:19
[ bkero ] [ epitron ] [ gnusha ] [ milkshakes] [ strangewarp ] 06:19
[ CapNemo ] [ falmot ] [ ivan` ] [ nuba ] [ superkuh ] 06:19
[ cryptic ] [ fenn ] [ jrayhawk ] [ pasky ] [ uniqanomaly__] 06:19
[ dbolser ] [ ferrouswheel] [ kanzure ] [ poptire ] [ Utopiah ] 06:19
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-!- Channel ##hplusroadmap created Thu Feb 25 23:40:30 201006:19
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Stee|_kanzure, is there a good hplus online journal in the style of an academic journal?07:19
Stee|_ie requiring a specific LaTeX format, citations, etc.?07:19
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kanzure"09:17
kanzureThe mythical “$1,000 genome” will be here next year, said Jonathan Rothberg, CEO of sequencing technology company Ion Torrent, at MIT’s Emerging Technology conference,"09:17
kanzurewelp, time to start collecting hair samples from celebrities09:17
kanzureor professors09:18
Steel_kanzure: Utility level of an open publishing online journal for diy/not so diy hplus stuff, with original authors pointing out areas that further work could be developed?09:19
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eudoxiaH+ arxic09:22
eudoxiaarxiv*09:22
eudoxiaI'm not sure why but it sounds hilarious09:22
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kanzureSteel_: rightn ow we call that blogs09:29
Steel_yeah09:30
Steel_those are terrible, disjointed, and don't require citations09:30
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kanzureso the p16 surface marker antagonist looks a little peculiar..10:21
kanzureit's in the news this week for "pausing" aging10:21
kanzureby killing senescent cells10:21
kanzurebut this seems suspect because aging isn't necessarily caused by non-dividing cells10:22
kanzure"I wonder if it would be possible to produce a humanized monoclonal antibody against p16-INK4a and via regular infusions, eliminate senescent cells immunologically.  These cells already are cleared by the immune system within reason, however they still manage to make up 5-10% of the cell population."10:26
kanzure"A problem is p16-INK4a is intracellular so antibodies may not get to them.  Need to find a  senescent-cell specific surface receptor."10:26
kanzure"Another key finding -- only shown in the supplements and barely mentioned in the paper -- is that clearing senescent cells had no effect on lifespan.  They say this is due to these mice dying primarily of heart disease which is not affected by the treatment.  So while the study shows that senescent cells can cause age-related phenotypes they seem to only contribute to a subset of these."10:27
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antipragmatisthi people.15:34
antipragmatisthey kanzure.15:34
antipragmatisthow are doing this eveni15:34
antipragmatisti'm setting micrometer screws on my stm15:35
kanzureokay.15:35
antipragmatistthat is great, im fine too. i'm setting up micrometer screws have you done this before? I need to insure it is accurate15:37
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antipragmatistmicrometer calibration is difficult15:52
antipragmatistthinking about creating myself a laser interferometer to facilitate15:53
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kanzurehttp://www.gaite-lyrique.net/les-conferences/evenement/do-it-yourself-biology#.TrKt8EPcSDo.twitter17:20
kanzurehrm why don't i get to be in france17:20
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* ybit just read logs of conversations with an ex-gf17:54
ybitgirlfriends are such a blissful hell17:54
ybitand a terribly inefficient use of one's time17:55
ybitand i state the obvious too often17:55
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Stee|kanzure, I told you about shapiro's papers on nanoparticle control in fluidic systems right?19:18
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kanzureuhh possibly19:37
kanzurei've read lots of shapiro stuff, i think19:37
Stee|has anyone in the diybio community implemented?19:38
kanzureno- can you link to the paper again?19:43
Stee|yeah19:44
Stee|http://drum.lib.umd.edu/bitstream/1903/9437/1/ChaudharyShapiro_SteeringOfMultipleParticesByEOF_IEEECST_Jul06.pdf19:45
Stee|http://web.mit.edu/andrew3/Public/Papers/2005/Armani/2005_Int%20J%20Robust%20Nonlin_Control%20of%20microfluidic%20systems%20two_Armani.pdf19:45
Stee|there's some other literature as well19:45
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convivialhi kanzure20:36
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DetergentizerHi kanzure20:36
kanzurehi Detergentizer20:38
Detergentizerhi.20:38
DetergentizerI had a queestion but forgot.20:38
Detergentizer:(20:38
Detergentizerdo u know anyone selling a CNC cheap?20:39
Stee|'cheap'20:39
Detergentizerthat url about molding ones own safm from plastic is  more expensive than buying one.20:39
Detergentizeryou need some kind of ijection modling system20:40
Mariusee you guys20:40
Detergentizerso if I can find a cheap CNC I can make one from steal20:40
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Detergentizeroh that is the question.20:42
Detergentizerkanzure:  do you hafe cnc so how much do you chaerge to make part20:42
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kanzureyeah make one from steal21:13
foucistkanzure: so, you are not aware of any cheap CNCs?21:40
kanzurehttp://img600.imageshack.us/img600/948/29316400025966429506346.jpg21:51
kanzurefoucist: yeah, there's tons21:51
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--- Log closed Tue Nov 08 00:00:32 2011

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