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eudoxia | hey, everybody. the Roadmap says this: "* Where is the old grass-roots open source group that was researching worm mind-uploading? | 02:50 |
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eudoxia | " | 02:50 |
eudoxia | and i think the answer to the question is http://groups.google.com/group/openworm | 02:50 |
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kanzure | eudoxia: nope, it was actually called MURG | 06:57 |
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kanzure | http://hardware.slashdot.org/story/11/11/10/1353240/shanghai-government-proposes-100-community-hackerspaces | 07:17 |
JayDugger | Hey, kanzure. | 07:23 |
JayDugger | Thank you for your help yesterday. | 07:24 |
JayDugger | Turns out the position with Objet requires "up to 80% travel". | 07:25 |
kanzure | that sounds fun | 07:25 |
kanzure | what's the position? | 07:25 |
JayDugger | The word I have in mind lacks an "n," but it starts with "f" and "u" in that order. | 07:25 |
JayDugger | They've a similar position in Indianapolis, IN. | 07:26 |
kanzure | what's the position? | 07:26 |
JayDugger | http://jobview.monster.com/Field-Service-Engineer-Job-Indianapolis-IN-US-103207079.aspx | 07:26 |
kanzure | field service engineer? o.O | 07:26 |
JayDugger | If that link fails, I'll email it to you or paste it. | 07:26 |
JayDugger | Yeah...basically what I did for my former employer. Not bad, but very hard on marriages. | 07:27 |
kanzure | are you unemployed? | 07:27 |
JayDugger | No. | 07:27 |
JayDugger | If I was, that'd be different. | 07:27 |
JayDugger | Depending on their salary offer, it might mean a big pay cut. | 07:28 |
kanzure | http://boingboing.net/2011/11/09/library-builds-a-hackerspace.html | 07:28 |
JayDugger | Good for that library! | 07:29 |
JayDugger | The first thing they make should be a cell phone jammer. | 07:29 |
JayDugger | Wow...and half-way intelligent comments on BB. | 07:32 |
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kanzure | the libraryspace should build a book scanner bot | 07:46 |
kanzure | it will ride around on the shelves, pull a book and scan it | 07:46 |
JayDugger | Right after the cell phone jammer, yes. | 07:46 |
kanzure | then it will incinerate the book with lasers | 07:46 |
JayDugger | Ha-ha! | 07:46 |
JayDugger | Lasers are good, flamethrowers are better! | 07:47 |
JayDugger | (You don't have to wear safety goggles with flamethrowers.) | 07:47 |
JayDugger | And another robot that goes up to random patrons and says "Sh!" | 07:48 |
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Utopiah | http://hardware.slashdot.org/story/11/11/10/1353240/shanghai-government-proposes-100-community-hackerspaces | 08:26 |
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falmot_ | http://ansistego.sf.net/ansi-mods.tgz | 08:59 |
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kanzure | what is thingdoc | 15:56 |
kanzure | https://github.com/prusajr/ThingDoc | 15:57 |
kanzure | hrmm | 15:57 |
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delinquentme | so of these disciplines: structural biology, biotechnology, cell biology, bioinformatics and systems biology | 18:39 |
delinquentme | which would the brains here regard as the best route to human life extension | 18:39 |
kanzure | o_O why are you categorizing things like this | 18:40 |
kanzure | the best route is asskicking | 18:40 |
kanzure | immortality or bust! | 18:40 |
delinquentme | lol | 18:41 |
delinquentme | that .. is | 18:41 |
delinquentme | apparent? | 18:41 |
delinquentme | lolol | 18:41 |
klafka | the best route is not going to be methodological but paradigmatic | 18:50 |
klafka | actually the 'best route' is going to be physics and industrial manufacturing really | 18:51 |
klafka | IMO | 18:51 |
epitron | delinquentme: a biological system is an integrated whole -- those are just knowledge divisions to make it easier for people to specialize... they're all important to life extension | 18:52 |
klafka | biology needs transformational hardware which will drive the ability to cheaply and quickly answer biological questions | 18:52 |
epitron | yep | 18:52 |
epitron | in other words, biotechnology -> bioinformatics -> cell biology & systems biology | 18:52 |
epitron | which feed back into bioinformatics | 18:52 |
klafka | for instance, a way to real time understand protein movement in cells, protein quantities in cells and fuck while we're wishing protein/RNA conformational states in cells | 18:53 |
klafka | on a mass scale | 18:53 |
klafka | another thing obviously would be a way to effectively and cheaply write DNA | 18:54 |
epitron | you know whats good at writing DNA? | 18:54 |
epitron | cells! | 18:54 |
klafka | heh | 18:54 |
epitron | we should hack bacteria to respond to print DNA like tickertape in response to flashing lights | 18:54 |
epitron | via rhodopsin implanted in the cell wall | 18:54 |
klafka | like the 'camera bacteria' | 18:55 |
epitron | what's that? | 18:55 |
epitron | nevermind, i googled :) | 18:55 |
klafka | there were some GE bacteria that basically acted like a camera, expose them to an image | 18:55 |
klafka | right | 18:56 |
epitron | that's kinda neat | 18:56 |
delinquentme | was an iGem project | 18:56 |
epitron | sounds pretty simple | 18:56 |
delinquentme | so PROGRAMING is part of it | 18:56 |
delinquentme | bc machine efficiency is a huge part of it | 18:56 |
joshcryer | bio is too hard for me to grasp :( | 18:57 |
epitron | programming what to make what machine efficient? | 18:57 |
delinquentme | the conceptual aspect is huge for someone to actually be able to bound through and mess with the comcepts of it | 18:57 |
epitron | joshcryer: not with THAT attitude! | 18:57 |
delinquentme | epitron, programming not only in applications of running shit like liquid handling | 18:57 |
delinquentme | but also in bioinformatics and even simple data processing | 18:58 |
epitron | programming the cell? | 18:58 |
delinquentme | that'd be hot. | 18:58 |
delinquentme | :D | 18:58 |
joshcryer | epitron, it's equivalent to alchemy, to me. | 18:58 |
delinquentme | right now the bio if fucking black magic to me | 18:58 |
delinquentme | ehhh well | 18:58 |
delinquentme | not black magic | 18:58 |
joshcryer | I saw that thing about the imaging bacteria, I think it was an ecoli strain. | 18:58 |
delinquentme | probs | 18:58 |
joshcryer | They didn't explain how they did it to any usable detail, that I saw (I didn't read any papers, if any were released, midn you). | 18:59 |
delinquentme | yeast is another good model organism to play with joshcryer | 18:59 |
delinquentme | joshcryer, more interesting is how to vector in proteins into differentiated cells in order to IPP them | 18:59 |
epitron | <delinquentme> epitron, programming not only in applications of running shit like liquid handling | 18:59 |
epitron | i still don't know what you're talking about :) | 18:59 |
delinquentme | making pictures with bacteria is novel but... there are more useful things | 19:00 |
delinquentme | epitron, so im a programmer turned sane | 19:00 |
delinquentme | thus im like " how can i save my ass asap " | 19:00 |
epitron | are you talking about programming software? | 19:00 |
epitron | microfluidic control systems? | 19:01 |
delinquentme | and so im outlining all the different diciplines involved with pushing life extension | 19:01 |
joshcryer | delinquentme, I was amused to learn that proteins can be separated from cells with a household detergent, then you layer on new cells that you've grown in a lab, and volia, you have a working organ or whatever with no immunosuppresant need. | 19:01 |
delinquentme | epitron, thats just what ive worked on | 19:01 |
epitron | outlining? more like scribbling in crayon | 19:01 |
delinquentme | epitron, ha | 19:01 |
delinquentme | so im saying that ... these are all the things which are worthwhile | 19:02 |
delinquentme | joshcryer, im not sure it was as simple as house hold detergent? | 19:02 |
joshcryer | AI IS THE FUTURE | 19:02 |
delinquentme | AI is part of it | 19:02 |
joshcryer | delinquentme, http://en.wikipedia.org/wiki/Protein_purification (sodium dodecyl sulfate) | 19:03 |
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joshcryer | I saw an episode of NOVA that discussed how they discovered it. | 19:03 |
joshcryer | They literally just brute forced it until they figured it out. | 19:03 |
delinquentme | you got a link for that? | 19:04 |
epitron | yeah, that sounds good :) | 19:04 |
joshcryer | Eh, it's been awhile, sorry. It was in the last 6 months to a year. | 19:04 |
joshcryer | Let me look then. :) | 19:04 |
epitron | danke! | 19:04 |
delinquentme | so i know we've stripped tracheas | 19:06 |
delinquentme | spelling? ^ | 19:06 |
delinquentme | but i wasnt so sure about the process of stripping away the foreign material | 19:06 |
delinquentme | but rebuilding on the scaffolding sounds simple enough | 19:07 |
joshcryer | Ahh. | 19:07 |
delinquentme | put cells on stuff .. incubate stuff | 19:07 |
joshcryer | It wasn't NOVA, it was NOVA ScienceNow: http://www.pbs.org/wgbh/nova/body/can-we-live-forever.html | 19:07 |
delinquentme | joshcryer, you do know about organovo right? http://www.organovo.com/products/novogen-mmx-bioprinter | 19:07 |
joshcryer | delinquentme, the impression I got was that it works with all organs, they have hearts and lungs working so far, but nothing precludes it from working with all of them, as far as I understood. | 19:07 |
delinquentme | O_O; | 19:08 |
delinquentme | was this a human organ? | 19:08 |
delinquentme | dont they swap in pig hearts? | 19:08 |
delinquentme | im wanting to say thats been done before .. but the same immuno suppressant stuff is involved | 19:09 |
joshcryer | yes for the protein shell, but it's human cells for the structure | 19:09 |
joshcryer | They're working on cloning the protein shell. | 19:09 |
joshcryer | I am so tired of the low info content of shows these days. That whole 13 minute clip the relevant part is about 2 minutes. :( | 19:11 |
delinquentme | haha | 19:11 |
delinquentme | id fucking LOVE more sci education | 19:11 |
joshcryer | 6m40s is where they start explaining the protein framework of organs. | 19:12 |
delinquentme | JESUS ITS BEUAUTIFULLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL | 19:13 |
delinquentme | LUNGS | 19:13 |
delinquentme | GROWN | 19:13 |
joshcryer | (the other stuff is just the dated ears on mice stuff) | 19:13 |
delinquentme | GOD DAMN HELL YES> | 19:13 |
joshcryer | Yeah, it's 5-10 years out, max | 19:13 |
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joshcryer | (and heart disease will be effectively cured, though expensively) | 19:17 |
delinquentme | my problem might be the fact that I want to do it all | 19:19 |
joshcryer | That is definitely a problem. | 19:20 |
delinquentme | machine learning observing bio simulations run in silico to then govern what should we break out into actual cell and chemical trials | 19:21 |
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delinquentme | whats up with the ear on the mouse | 19:26 |
delinquentme | wouldnt the mouse have immuno issues? | 19:27 |
delinquentme | commonly found in shampoo | 19:30 |
delinquentme | STFU | 19:30 |
joshcryer | the ear mouse thing is so old | 19:31 |
joshcryer | this whole stripping organs of cells thing and preserving the protein structure is awesome | 19:32 |
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--- Log closed Fri Nov 11 00:00:37 2011 |
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