2011-12-21.log

--- Log opened Wed Dec 21 00:00:38 2011
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kanzurefenn: hi06:46
kanzure"The idea behind the07:08
kanzureresearch was to try to find out what genetic changes might make the virus07:08
kanzureeasier to transmit. That way, scientists would know how to identify changes07:08
kanzurein the naturally occurring virus that might be warning signals that it was07:09
kanzuredeveloping pandemic potential. "07:09
kanzuregee thanks NIH07:09
kanzure“My concern is that we don’t give amateurs — or terrorists — information that07:09
kanzuremight let them do something that could really cause a lot a harm,” he said in07:09
kanzurean interview.07:09
kanzureuhuh07:09
kanzure"amateurs -- OTHERWISE KNOWN AS TERRORISTS--"07:10
superkuhIt's incredibly stupid. The best way to decrease the pathogenicity of a virus is to pass it through multiple non-human hosts. And ferrets are horrible models of pathogenicity; as can be seen by the very high mortality they have with H1N1 novel origin from 2009. They are only useful models for virulence because they share the sialic acid sugars on the their upper respiratory epithelial cells as humans.07:15
superkuhAnd that's not even acknowledging that the H1N1 1918 strain sequences are already published and widely distributed; a strain that *does* have high virulence and is highly pathogenic in humans.07:16
superkuhs/the their/their/07:16
superkuhThis entire media storm is being manufactured for it's value in justifying censorship.07:17
superkuhIt's not like the information isn't out already anyway. The NSABB only got involved after peer review.07:18
kanzureferrets did seem like an odd choice to me, but i'm not familiar with them in research07:18
superkuhLike I said, they are the standard model for human influenza virulence because their sialic acid sugars, where the neuraminidase proteins on the influenza bind to enter the cell, are very close to human.07:19
kanzureso anyway, this study could be anything- theoretical genetic changes that would cause greater virulence, or even actual tests07:20
kanzurei sorta doubt actual tests of viruses or any sort of directed-evolution-to-see-which-strain-comes-out-on-top07:20
kanzureprobably just a theoretical study.. "hurr you can clearly change the incubation period with these four snps"07:21
superkuhI doubt they did even cell culture based tests for human pathogenicity; and if they did it wouldn't be reliable. All statements about the danger of the virus cannot be justified from ferret models.07:22
kanzuresuperkuh: a lot of the lame ducks in the diybio community have gotten by on saying "Oh, making a virus is too complicated or cost-prohibitive for amateurs to do"07:48
kanzurefrankly i don't believe that line07:48
kanzurethere are many individuals with a few mil laying around07:49
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JayDuggerGood morning, everyone.08:03
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uniqanomaly“we don’t give amateurs — or terrorists — information that might let them do something that could really cause a lot a harm,”08:36
uniqanomalyare chemistry books in public libraries still legal in US? lol08:37
uniqanomalyand selling them to anyone ;>08:38
uniqanomalyauthorisation levels for knowledge, unauthorized knowledge punishable by death!08:41
klafkasuperkuh it's not surprising08:43
klafkareally08:43
uniqanomalythey should really think about it after SOPA08:43
klafkathey're  quite possibly going to try and push sopa through again08:54
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kanzureyummy https://github.com/mathphreak/keyboard.backbone.js09:22
kanzurehttp://mir.aculo.us/2011/09/08/insanely-easy-keyboard-shortcuts-for-your-web-apps-%E2%80%94-keymaster-js/09:23
kanzurenot sure how to manage 'contexts' or 'modes' like if a user is viewing one thing versus another09:23
kanzureklafka: status update? you're definitely going w/ factual?09:34
klafkabadgeville09:34
klafkaactually09:34
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kanzureeudoxia: did you watch it?09:45
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Mariusee you all later14:41
kanzurenope14:43
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ybitso much for using rpy :\14:56
klafkanot good?15:13
ybiteh, it doesn't support the version of r in the repo and the build fails and i'm not messing with it15:20
ybitsource build*15:21
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kanzure"We should be building defences because of the risk of random mutations and not because of the risk of engineered viruses."15:58
strangewarpGood luck convincing anyone who went to statist war school, especially anyone who loves their terr'...16:06
kanzurei don't think statist war school teaches combat against mother nature16:08
strangewarpexactly :p16:08
sylph_makomutations in what?16:27
kanzurenatural mutations in various viruses, it doesn't matter really16:28
kanzurethe point is, viruses are a natural phenomenon so it doesn't matter if it's man-made or not16:28
kanzure*if a particular instance is man-made or not16:28
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kanzureybit: orgmode in a browser http://yata.in/docview/r/4ed70c031a7ba32edb00000217:07
ybitinteresting17:32
ybitthere's an android app for syncing your orgmode files17:33
ybithttp://mobileorg.ncogni.to/17:33
ybithaven't yet went through the process of syncing17:33
ybithttp://vizualize.me/17:41
ybit"Vizualize your resume in one click."17:41
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kanzureybit: that looks like spam to me19:05
kanzurehttp://www.ottawacitizen.com/health/Canadians+start+vaccine+clinical+trials/5890341/story.html19:09
kanzureanyone have the link to the patent?19:09
JayDuggerHow did you find "orgmode in a browser"?19:39
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kanzureJayDugger: google psychic search services20:09
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ybithttp://imgur.com/a/OPQE922:23
ybitthere seems to be a common pattern here, something pushing or pulling people from searching for programming related terms?22:25
ybiti'm probably missing some basic notion from stats 10122:26
kanzureprobably school22:27
kanzureare those weekends?22:27
ybithrm?22:28
kanzureautodesk acquired instructables? i thought it was someone else23:32
kanzure"On December 2009, Autodesk announced the acquisition of VisualTAO (also known as PlanPlatform), an Israeli start-up that developed a cloud-based Web application, enabling users to view and edit AutoCAD files online. The company also developed a mobile version of the application. VisualTAO became part of PSEB, and the product was released during 2010 as "AutoCAD WS.""23:32
kanzuredidn't know autocadws was an acquisition23:38
--- Log closed Thu Dec 22 00:00:39 2011

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