| --- Log opened Mon Feb 06 00:00:58 2012 | ||
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| kanzure | heh 3d prited hermit crab shells | 06:28 |
|---|---|---|
| kanzure | why is ray kurzweil appearing in superbowl ads | 06:29 |
| kanzure | http://www.youtube.com/watch?v=rLzXmcTzka4 | 06:30 |
| kanzure | *printed | 06:31 |
| kanzure | http://news.ycombinator.com/item?id=3557074 blah blah blah tdcs has imprecise electrode placement | 06:37 |
| uniqanomaly | you guys seen that? http://2045.com/ | 06:37 |
| kanzure | i don't see any of the normal russian transhumanists | 06:41 |
| kanzure | http://2045.com/experts/ | 06:41 |
| kanzure | http://2045.com/manifest/28611.html | 06:42 |
| kanzure | http://2045.com/plan/28695.html | 06:42 |
| kanzure | http://2045.com/open-letter/28610.html | 06:42 |
| kanzure | strange. | 06:44 |
| uniqanomaly | kanzure: what exactly? | 06:44 |
| uniqanomaly | oh, "i don't see any of the normal russian transhumanists" that? | 06:45 |
| kanzure | the absence of the normal suspects | 06:45 |
| kanzure | like ~Uжов ~\а~Bвей ~Tми~B~@иеви~G | 06:45 |
| kanzure | oleg yermakov, alexey potapov, Сажин, zhitelew, pashuntiy | 06:47 |
| kanzure | igor artyuhov.. valerijapride, danila medvedev, andrey bashmakov | 06:48 |
| uniqanomaly | http://thesingularity.com/videos/dmitry-itskov-on-project-immortality-2045 | 06:53 |
| uniqanomaly | http://www.youtube.com/watch?v=zEi3ZAYheT0 here's official vid | 06:54 |
| uniqanomaly | not worth watching | 07:05 |
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| kanzure | spfldcol.edu has a lot of subscriptions.. | 08:02 |
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| fenn | there is some evidence for oxidative stress as the trigger for the beneficial effects of exercise (see work of michael ristow) | 09:02 |
| fenn | heh steven seagal appears again | 09:04 |
| fenn | "Renowned actor and martial artist Steven Seagal has written an open letter to Russian Prime Minister Vladimir Putin, asking the Prime Minister’s support of the “Russia 2045” movement that aims to make Russia the center of immortality and artificial body research." | 09:06 |
| fenn | kests is cute and a much better version of the "space elevator" but unfortunately it has the same material strength problems due to being 100Mm long | 09:08 |
| fenn | i'd rather publicize rotating tether concepts such as on tethers.com | 09:09 |
| fenn | they are actually feasible to build today, with today's budgets ($50M) | 09:10 |
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| superkuh | Their electrodynamic tether concepts are amazing. | 09:20 |
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| delinquentme | howdy all! | 09:51 |
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| kanzure | hi delinquentme | 09:54 |
| delinquentme | http://www.nature.com/news/one-genome-from-many-1.9969 <<< im looking at this paper and im unable to figure out why its significant | 09:55 |
| kanzure | well, it looks like they don't want to do separation by molecular weight | 09:57 |
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| jrayhawk | fenn: there's also the research that indicates that antioxidant supplementation worsens some cancers and heart disease | 11:18 |
| jrayhawk | or, rather, people who are long-term antioxidant supplementers have worse outcomes for cancers and heart disease | 11:23 |
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| delinquentme | http://boingboing.net/2012/02/06/zapping-the-brain-into-exper.html?utm_source=dlvr.it&utm_medium=twitter | 11:32 |
| delinquentme | kanzure, ^^^ this requires NO internal electronics?? | 11:32 |
| kanzure | tcds? | 11:35 |
| strages | tDCS yes | 11:39 |
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| delinquentme | omg its Mokbortolan_1 ! | 11:52 |
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| Mokbortolan_1 | It is?!? | 11:56 |
| Mokbortolan_1 | where?! | 11:56 |
| * Mokbortolan_1 gets his camera. | 11:56 | |
| Mokbortolan_1 | oh hey, I'm working on tDCS | 11:56 |
| Mokbortolan_1 | me and another fellow are working on a schematic over at reddit.com/r/tdcs | 11:57 |
| delinquentme | what is tCDS? | 11:59 |
| delinquentme | YEH that mok thing is here! | 11:59 |
| delinquentme | PS im about to write a possible PI ... suggestions other than "please give me a job" | 11:59 |
| Mokbortolan_1 | transcranial direct current stimulation | 11:59 |
| delinquentme | STFU | 12:00 |
| Mokbortolan_1 | basically you add a few mA of current to a section of the brain, and depending upon the polarity you can raise or lower the "activation threshhold" for the neurons there | 12:00 |
| Mokbortolan_1 | there's another term for it | 12:00 |
| Mokbortolan_1 | so you make it easier or harder for them to fire | 12:00 |
| delinquentme | TIL 9volts can kill you | 12:01 |
| Mokbortolan_1 | indeed | 12:01 |
| Mokbortolan_1 | although, it's the amps that do it | 12:01 |
| delinquentme | Mokbortolan_1, are you an electrician? | 12:01 |
| Mokbortolan_1 | no, I'm a polymath | 12:01 |
| delinquentme | GOD im so glad we've got the people we do in here | 12:01 |
| delinquentme | good answer :D | 12:01 |
| delinquentme | but you're capable with electronic circuits and the like? | 12:01 |
| delinquentme | when I pick my liquid handler back up i'd be really interested in getting some feedback on some of the circuit layouts | 12:02 |
| Mokbortolan_1 | yes, I'm fairly handy with a soldering iron | 12:02 |
| Mokbortolan_1 | I'm no EE, but I can make an LED light up and not burn out :p | 12:02 |
| Mokbortolan_1 | the circuit we're working on (well, the one that I've got to draw and build now) is far safer than the original potentiometer-only model | 12:03 |
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| Mokbortolan_ | looks like I'm due for a router reset | 12:08 |
| kanzure | damn it why can't we phase out physical mail from being a socially acceptable way to send email | 12:09 |
| kanzure | it is *not* ok | 12:09 |
| Mokbortolan_ | "Way to kill a tree, snail-mail" | 12:10 |
| kanzure | so, i hate that i have to pay to print and send to people who want physical copies | 12:15 |
| kanzure | i'd rather pay for a physical mail sending api | 12:15 |
| kanzure | there's a fedex printer driver that you can install, but i don't know if it lets you type in the destination address | 12:15 |
| kanzure | also it seems to be windows-only. | 12:16 |
| jrayhawk | It's illegal for them to transport first-class letters. | 12:16 |
| kanzure | fax machines sorta solved this (for their time) | 12:16 |
| kanzure | but with email now, fax machines are just stupid- beyond stupid | 12:16 |
| delinquentme | just spent 10 minutes ranting about the awesomeness of calculus to my little brother | 12:16 |
| kanzure | so hellofax is a fix on top of the fix | 12:16 |
| * delinquentme smells like corn chips | 12:16 | |
| kanzure | but hellofax doesn't actually fix it! it just sends your fax to email | 12:16 |
| kanzure | the point of a fax machine was to have it printed out | 12:17 |
| kanzure | so at the very least, hellofax should have a "manage your inbox, here's a queue of things that you might want to choose to print" ui thing.. i don't know | 12:17 |
| kanzure | (hellofax does hosted virtual fax machines) | 12:17 |
| jrayhawk | IIRC google's phone services do that, too | 12:17 |
| kanzure | nice. | 12:18 |
| kanzure | i hate sending emails as physical mail. you mean i have to pay for transmission + ink + paper because you don't want to print it out yourself? then doesn't that mean you want email.. i.e. the value of it being printed is not great enough for you to justify the cost of printing | 12:18 |
| kanzure | the receiving party should be responsible for paying for transportation/delivery/printing, not the sender (if the sender is sending by email) | 12:19 |
| jrayhawk | I'm afraid the postal union is a bit better politically entrenched than you are | 12:19 |
| kanzure | there's lots of b2b or b2c bulk mailing companies, but nothing that's at the same market level as hellofax really.. fedex's print driver might be an exception, but i'm not convinced it solves the problem | 12:20 |
| kanzure | if anything, there should be a service that physically prints my mail, or hooks up to a remote printer driver at the destination office | 12:20 |
| kanzure | fax machines are weird.. auto-printing incoming stuff. but why do people still use them? is there really no sufficiently usable "show me a to-print queue from my email inbox"? | 12:21 |
| kanzure | so! how about a physical mail printing service. you send an email to your recipient, and carbon copy the email to this service. | 12:23 |
| kanzure | it responds back to your email thread with an invoice/bill for the cost of printing, which either party can pay | 12:23 |
| kanzure | either party can setup their account on this service to, say, "pay 50% of the fee; default to email-only delivery for me please" | 12:23 |
| kanzure | so if two parties are email-only, then nothing happens | 12:24 |
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| kanzure | if one party is email only but he's willing to pay 50%, and the other party doesn't know wtf this is, maybe he'll figure the value of printing and receiving the physical letter is high enough and pay the 50%.. or just decide "nevermind, sending by email is fine" | 12:24 |
| kanzure | then there can be an artificial premium on physically printing stuff out :) like 40% or something. "well you see, it costs us so much to print and then there's postage fees and envelopes.." | 12:26 |
| kanzure | if the other party thinks the fee is too high, but still wants it physically printed, he can either print it himself or find a cheaper api. either way it solves the problem for the email-only person who was sending it | 12:26 |
| kanzure | jrayhawk: thoughts? | 12:27 |
| kanzure | oh also- this would work for sending in mail to nameless corps where you can't send that printing/delivery invoice to them. but in these cases you'd have to foot the bill (or it would be subsidized by your monthly subscription fee to this service) | 12:28 |
| kanzure | delinquentme: did you teach him anything | 12:34 |
| jrayhawk | thoughts: basically the only time anything good happens to USPS service it's because the supreme court orders it | 12:37 |
| jrayhawk | I guess the postal regulatory commission does nice things sometimes, too | 12:38 |
| kanzure | i'm pretty sure this would route around usps | 12:39 |
| kanzure | i mean, it would probably use usps for the actual sending part when some asshole really wants a physical version | 12:39 |
| kanzure | but by that point they already confirmed that they want to receive physical mail | 12:39 |
| jrayhawk | the usps gives you legal protections that nobody else can | 12:40 |
| kanzure | true, legally sensitive documents should probably not be sent by email | 12:40 |
| kanzure | or rather *not be sent by poorly maintained, unencrypted, who-knows-is-hosting-it email | 12:40 |
| fenn | when talking about "should" you can't neglect to discuss public key cryptography | 12:40 |
| fenn | anyone can drop some crap in a mailbox and put my name on the return address | 12:41 |
| jrayhawk | The USPS is the only system where you can send somebody something and it becomes their liability for their failure to read it | 12:41 |
| jrayhawk | or to claim of failure to have received it | 12:42 |
| kanzure | wait what | 12:42 |
| kanzure | i just ignore my mailbox and set everything to email-only | 12:42 |
| kanzure | i wonder if there's random jury duty notices in there | 12:43 |
| jrayhawk | haha | 12:43 |
| kanzure | "holy crap! i have to be in court in 20 minutes!" comedy ensues | 12:44 |
| jrayhawk | So whatever you're proposing would take an act of congress to make broadly usable, so, once again, you'd be fighting the postal union. | 12:45 |
| kanzure | huh? what i'm proposing would still use usps | 12:45 |
| jrayhawk | I'm glad businesses are occasionally willing to settle for email billing. | 12:45 |
| jrayhawk | Oh, well, in that case, you're directly fighting the postal union. | 12:45 |
| kanzure | but instead of *me* paying for postage and printing and paper and a printer, someone else does unless they find the value of the physical doc less than the cost of printing | 12:46 |
| delinquentme | kanzure, yeah! | 12:46 |
| delinquentme | talked about how math is like hacking | 12:46 |
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| delinquentme | theres tons of different ways to get any one solution | 12:46 |
| jrayhawk | But, hey, literally anything's better than what we have now, so I'm in support of your plan. | 12:46 |
| delinquentme | and so long as the mechanics are right you're golden! | 12:46 |
| jrayhawk | Despite having only glanced over it | 12:46 |
| delinquentme | and then he kinda blew my mechanics and showed me up | 12:46 |
| jrayhawk | and really doubting it will go anywhere because good ideas don't survive in politics | 12:46 |
| kanzure | jrayhawk: the brief version is, "email the doc to them; printing/mailing service gives the other party a bill/invoice. either party can pay the bill to have it sent/printed." | 12:47 |
| kanzure | email is substantially cheaper compared to physical mailing, printing costs, envelopec osts, postage costs.. | 12:47 |
| jrayhawk | I was assuming there would be a USPS-proprietary message sending/receiving API, since email is not really practical for this purpose. | 12:48 |
| kanzure | if email was some new tech that nobody uses, i could see how physical printing would be more popular and why i should pay it -- but it's not.. email is standard now. | 12:48 |
| kanzure | ah i see | 12:48 |
| kanzure | yes this would just be for printable documents, and the service would still use usps to physically bring the atoms to the destination mailbox | 12:48 |
| fenn | you guys are not communicating with each other and should just stop | 12:48 |
| delinquentme | kanzure, use sendgrid | 12:49 |
| delinquentme | they're hot as | 12:49 |
| kanzure | sendgrid is email only i thought | 12:49 |
| jrayhawk | communicating is for suckers | 12:49 |
| delinquentme | ^^ | 12:49 |
| delinquentme | thats what i tell my female | 12:49 |
| delinquentme | she doesnt like it | 12:49 |
| delinquentme | what're you guys working on? | 12:49 |
| * delinquentme is not a mysogynist | 12:49 | |
| delinquentme | sexist yes | 12:49 |
| kanzure | fenn: do you know which microfluidic dna synthesis startup might know singularityu or andrew hessel? i haven't found any names :| | 12:50 |
| jrayhawk | does being a misanthrope technically make me a misogynist | 12:50 |
| delinquentme | kanzure, what about hessel? | 12:52 |
| delinquentme | i've talked to the guy | 12:52 |
| delinquentme | jrayhawk, you're on the next level bro | 12:53 |
| delinquentme | you're not distinguishing :D | 12:53 |
| kanzure | delinquentme: what do you mean what about him.. i already asked the question | 12:55 |
| kanzure | name a dna synthesis startup that knows andrew | 12:55 |
| kanzure | andrew hasn't given me the name yet. | 12:55 |
| delinquentme | OOO | 13:00 |
| delinquentme | so today someone connected the dots that | 13:00 |
| delinquentme | JOURNALS | 13:00 |
| delinquentme | PAY WALL | 13:00 |
| delinquentme | publically funded research | 13:00 |
| * delinquentme nods head | 13:00 | |
| kanzure | duh? | 13:01 |
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| delinquentme | is a paper is released on PLoS does that mean that the publisher specifically released it with an open license ? | 13:37 |
| kanzure | no plos is its own publisher | 13:52 |
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| delinquentme | kanzure, so its wrong to assume that a researcher supports open science if they happen to have a paper published in PLOS? | 13:55 |
| kanzure | plos is an ok outlet to publish, but it's relatively new | 13:56 |
| kanzure | i bet everyone who publishes in plos knows its history | 13:56 |
| delinquentme | http://glamm.lbl.gov/ this is BEAUTIFUL | 13:57 |
| kanzure | and i also bet that people who publish in plos have other journals that would potentially accept their submissions | 13:57 |
| kanzure | delinquentme: is this the one that juul works on? | 13:57 |
| delinquentme | kanzure, do you mean that PLoS is going out? or that they know what its about | 13:57 |
| kanzure | that they know its history and being about open access | 13:58 |
| delinquentme | kanzure, the app is from that primary researcher | 13:58 |
| kanzure | plos isn't really going out as far as i can tell, except for the general apocalypse that will destroy the 'journal' concept | 13:58 |
| delinquentme | and yeah this is the position working under that guy ... arkin | 13:58 |
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| kanzure | oh this looks like a bad version of reactome | 13:58 |
| kanzure | awful | 13:58 |
| kanzure | http://www.reactome.org/cgi-bin/frontpage?CLASSIC=1 | 13:59 |
| kanzure | hover over the items | 13:59 |
| kanzure | hrm this is worse than i remembered it. | 14:01 |
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| Mokbortolan_ | http://falstad.com/circuit/ | 14:29 |
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| kanzure | Juul: delinquentme was looking at glamm.. is that you? | 14:50 |
| Juul | kanzure, nope | 14:50 |
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| delinquentme | thats a really pretty app :D | 15:58 |
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| delinquentme | techno-lol? http://www.kurzweilai.net/salmon-dna-based-memory-device | 16:14 |
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| roksprok | Mokbortolan_: how is your tdcs device coming along? | 16:29 |
| Mokbortolan_ | I got the LM334's in the other day | 16:30 |
| Mokbortolan_ | I picked up a resistor assortment today | 16:30 |
| Mokbortolan_ | still need to get a 300 ohm pot | 16:30 |
| Mokbortolan_ | and then I get to figure out how to make circuit boards :) | 16:31 |
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| delinquentme | Mokbortolan_, you in #robotics | 16:34 |
| delinquentme | they've got lots of ghetto ways to make em | 16:34 |
| Mokbortolan_ | naa, I mean, I know how, I just need to figure out how I'm going to do it this time | 16:36 |
| Mokbortolan_ | I don't have a nice drill press to do the through-holes | 16:36 |
| Mokbortolan_ | I'll probably just use breadboard | 16:36 |
| roksprok | where are you getting your parts? | 16:39 |
| roksprok | more the LM334's and potentiometer | 16:39 |
| roksprok | than the resistors | 16:39 |
| roksprok | Amazon has them but shipping looks to be a bitch | 16:39 |
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| delinquentme | yaw eudoxia =] | 16:41 |
| eudoxia | hello friends | 16:41 |
| delinquentme | can anyone grab this http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=5719724 ?? | 16:44 |
| Mokbortolan_ | roksprok: I got my regulators off ebay | 16:44 |
| Mokbortolan_ | because my credit card was in the car and I didn't want to have to get dressed :p | 16:44 |
| Mokbortolan_ | Convenience payment FTW! | 16:44 |
| roksprok | always a good reason | 16:45 |
| delinquentme | win | 16:45 |
| Mokbortolan_ | I'm thinking about putting together kits, but that's probably just my recent business activities bleeding over into my other hobbies :p | 16:45 |
| roksprok | Mokbortolan_: what are you using for electrodes? | 16:46 |
| Mokbortolan_ | cosmetic sponges secured to copper discs | 16:46 |
| Mokbortolan_ | they have a very fine texture and are good for this purpose | 16:47 |
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| Mokbortolan_ | at least, I think they are | 16:47 |
| roksprok | cool hope it works well | 16:47 |
| Mokbortolan_ | I'm sure some person more educated is going to tell me why they're a terrible idea | 16:47 |
| Mokbortolan_ | but until then I will proceed with unfettered ignorance | 16:47 |
| roksprok | well some guy on youtube just hooked sponges up to a battery and didn't die | 16:47 |
| Mokbortolan_ | yeah, that guy is what scares me about selling kits | 16:48 |
| roksprok | you'd have to include a big warning or three | 16:49 |
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| delinquentme | kanzure, what are the genomes called which people align sequences to? | 16:51 |
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| kanzure | delinquentme: reference genomes? | 17:11 |
| kanzure | "I think stating I am a fan may not be entirely appropriate to say to another directly, but I rather admire your commitment to the DIYbio community. Thanks for keeping it strong." | 17:12 |
| kanzure | what's wrong with being a fan | 17:12 |
| delinquentme | yeap but lando made an awesome suggestion | 17:15 |
| delinquentme | kanzure, someone wrote that to you? | 17:15 |
| kanzure | yes | 17:15 |
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| audy | zomg going to Shezhen | 17:21 |
| audy | gonna see where those reference genomes are sequenced | 17:22 |
| kanzure | lots of em were sequenced in the us | 17:22 |
| kanzure | do you mean shenzhen? | 17:22 |
| kanzure | or is this another place | 17:23 |
| kanzure | http://cadrequest.com/ some sorta community cad model requesting place | 17:34 |
| kanzure | this seems easy to game.. | 17:34 |
| kanzure | i'll just post a million requests for all patents | 17:34 |
| kanzure | i hope he can keep up | 17:38 |
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| audy | kanzure: Shenzhen sorry | 18:06 |
| audy | kanzure: The Chamber of 1000 Illuminas | 18:06 |
| kanzure | cool | 18:07 |
| kanzure | steal some genomes for me would you? :) | 18:07 |
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| yashgaroth | ey kanzure I drew up a picture of that oligo manufacturing process from yesterday's rant | 18:17 |
| yashgaroth | http://i.imgur.com/cl7Ng.jpg | 18:17 |
| delinquentme | ^^^ i hang out w the coolest kids on earth | 18:21 |
| delinquentme | true fucking story | 18:22 |
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| kanzure | yashgaroth: thanks | 18:33 |
| kanzure | delinquentme_: yep we're definitely the cool kid club | 18:34 |
| delinquentme_ | ^^^ | 18:34 |
| * Mokbortolan_ has never been in the cool kid club. | 18:34 | |
| kanzure | damn does this mean i need to make up diagrams for the other parts | 18:34 |
| delinquentme_ | lol but really! | 18:34 |
| kanzure | god damn it don't set the bar so high | 18:34 |
| delinquentme_ | we're toting around serious weaponry | 18:35 |
| delinquentme_ | we're talking about *HUGE* enemies | 18:35 |
| delinquentme_ | real shit | 18:35 |
| kanzure | enemies? | 18:35 |
| delinquentme_ | like what do some of the other friend I have talk about | 18:35 |
| delinquentme_ | how "we" ( XYZ football team ) kicked ass | 18:35 |
| * delinquentme_ gags | 18:35 | |
| delinquentme_ | kanzure, you know .. those who take public research and sit on it | 18:36 |
| delinquentme_ | enemies / undertakings .. projects | 18:36 |
| delinquentme_ | call it what you want | 18:36 |
| delinquentme_ | but gimme that small wildly optimistic group tucked away in the corner and ill put my money on them for who will make changes | 18:36 |
| delinquentme_ | simply | 18:37 |
| Stee| | I'm working on getting my rich investor friend interested in throwing more money at kanzure | 18:37 |
| delinquentme_ | better focuses than 90% of the world | 18:37 |
| kanzure | well i guess that's better than your poor investor friend? | 18:37 |
| kanzure | sarcasm side- sounds cool | 18:38 |
| Stee| | I'll be the poor investor friend soon :V | 18:38 |
| kanzure | delinquentme_: your goal should be to become 1000x more competent than anyone in here.. | 18:46 |
| delinquentme_ | thats quite the undertaking | 18:47 |
| delinquentme_ | like you alone have google beaten on depthy subjects | 18:47 |
| delinquentme_ | BUT why do you say this? | 18:48 |
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| delinquentme_ | kanzure, ^^ | 18:53 |
| yashgaroth | well, even if you only become 10x more competent than anyone else, that's pretty good | 18:54 |
| yashgaroth | also delinq why didn't you think that article at http://www.nature.com/news/one-genome-from-many-1.9969 was significant? cuz it hella is | 18:57 |
| kanzure | i vote delusional coma http://www.youtube.com/watch?v=rlnyjw5LUj0&t=10 | 18:59 |
| yashgaroth | delinq: 99% of microorganisms can't be grown in culture so you can't get a pure sample like with larger animals or e.coli | 19:01 |
| yashgaroth | craig venter spent a long time boating around the ocean sequencing random genes from shit out there, but if you're looking for whole biosynthetic pathways you need a whole genome | 19:02 |
| kanzure | isn't that just "how to figure out which segment belongs to which genome" in that link? | 19:03 |
| yashgaroth | basically yes, it's all bioinformatics based | 19:03 |
| yashgaroth | it's not a groundbreaking discovery, just good algorithm design | 19:04 |
| kanzure | i guess traditional assembly doesn't account for the possibility of an unknown number of genomes with possibly copied segments in each | 19:04 |
| kanzure | *in each, within the samples you feed it | 19:04 |
| yashgaroth | and they're doing it at UW-Seattle which automatically means it's awesome | 19:05 |
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| kanzure | flying quadrotor swarm http://www.youtube.com/watch?v=YQIMGV5vtd4 | 19:11 |
| kanzure | not sure why it's called nano | 19:11 |
| eudoxia | same here | 19:12 |
| eudoxia | god damm bandwagoning students | 19:12 |
| yashgaroth | because hopefully that's as small as quadrotors will get; if they get any smaller, they can just fly into your mouth and choke you to death | 19:12 |
| kanzure | maybe it was for the grant money | 19:12 |
| delinquentme_ | yashgaroth, yeah I had someone explain it | 19:12 |
| delinquentme_ | totes realize the gravity of it now | 19:13 |
| yashgaroth | okay good just checking | 19:13 |
| delinquentme_ | hes releasing the code in 6 months | 19:13 |
| delinquentme_ | ( ahem ) yeah see it when I believe it | 19:13 |
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| eudoxia | there's a physical limit to the size of wings/propellers that work | 19:14 |
| eudoxia | and I'm pretty sure it doesnt allow for choking quadrotors | 19:14 |
| delinquentme_ | eudoxia, its called nano bc its fucking streamlines turnkey optimized and actionable | 19:14 |
| yashgaroth | whew | 19:14 |
| delinquentme_ | streamlined* | 19:14 |
| delinquentme_ | dubstep anyone? | 19:15 |
| delinquentme_ | new nero is out | 19:15 |
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| kanzure | huh sigma adler is hosting sciencehackday chicago | 19:23 |
| eudoxia | wub wub | 19:23 |
| kanzure | contact point: Brian Carstensen <brian.carstensen@gmail.com> | 19:23 |
| delinquentme_ | eudoxia, ^_^ | 19:26 |
| kanzure | google ads are getting pretty specific for me | 19:26 |
| kanzure | "micro 3d printing from cad files microfluidics prototyping service" | 19:26 |
| eudoxia | hahah what the fuck | 19:26 |
| kanzure | "Spectrometers! High Throughput Gratings covering any range 190-2600nm" | 19:27 |
| kanzure | "Cy3, 3b, 5, 5.5 + 7 NHS/MAL/Amine Protein/Ab/ sml mol conjugations" | 19:29 |
| kanzure | how is that even an ad | 19:29 |
| yashgaroth | ehh they're offering to add fluorescent tags to your protein, my company just had a service do that exact same thing a few weeks ago | 19:32 |
| roksprok | kanzure: a few years ago i noticed that when I searched for incredibly uncommon phrases, the first time I would get like three results, but if i ever searched again I'd get hundreds of results, mostly porn or 'win an ipod!' type things. | 19:33 |
| yashgaroth | though I don't know why anyone shopping for that would use google ads to decide on a trustworthy company | 19:33 |
| roksprok | it was really creepy | 19:33 |
| delinquentme_ | stick this in the repository : http://guides.library.duq.edu/documenting_impact << this is a document outlining how duqesne university determines their research paper impact factors | 19:37 |
| delinquentme_ | probs come in handy somewhere down the line :D | 19:37 |
| delinquentme_ | roksprok, howdy. | 19:38 |
| delinquentme_ | havnt seen you chatting before either :D | 19:38 |
| roksprok | i've been lurking for about a week | 19:38 |
| delinquentme_ | roksprok, awesome glad to have you ... this is whereeeeee | 19:38 |
| delinquentme_ | cool things happen | 19:39 |
| roksprok | tbh this irc channel has been the most motivating thing i've ever come accross | 19:39 |
| delinquentme_ | i think i've become the unofficial cheerleader | 19:39 |
| kanzure | yashgaroth: yep i /totally/ decide on competent molecule vendors based on their google ads | 19:40 |
| kanzure | bleh their wording doesn't inspire confidence either | 19:40 |
| roksprok | i'm finally becoming optimistic about life-extension stuff happening in my lifetime | 19:40 |
| kanzure | if you can't write a good ad why would i trust you to do good chemistry | 19:40 |
| roksprok | does anyone know if there is a built in bill of materials in an EAGLE schematic or board file? | 19:43 |
| delinquentme_ | roksprok, awesome! | 19:44 |
| delinquentme_ | and I dont think so | 19:44 |
| delinquentme_ | but I've only used EAGLE files once or twice | 19:44 |
| delinquentme_ | roksprok, do you know we can reconnect severed nerves in a matter of hours now? | 19:45 |
| delinquentme_ | this medical process was published 2 days ago | 19:45 |
| roksprok | i did not know that no, exciting stuff! | 19:45 |
| delinquentme_ | researchers have now taken SKIN cells .. and directly influenced them to become neurons | 19:45 |
| delinquentme_ | this is skipping the whole IPP step | 19:46 |
| delinquentme_ | we're playing with the jelly of human tissue and making fucking SANDWICHES man | 19:46 |
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| yashgaroth | I certainly will once I can grow my own liver tissue in a dish, me-pate spread on everything | 19:48 |
| delinquentme_ | LOL | 19:49 |
| delinquentme_ | umm i see this as a pickup line | 19:49 |
| delinquentme_ | you should taste me I'm delicious | 19:49 |
| delinquentme_ | and then she instantly starts thinking you're hung like a horse | 19:49 |
| delinquentme_ | and you say nothing else | 19:50 |
| kanzure | roksprok: no but geda or some closely related tool has a bom format? | 19:51 |
| kanzure | shame on you for using eagle anyway | 19:51 |
| kanzure | "A while ago I spent a little time reading the literature on the symbiotic microbes responsible for bioluminescence in squid. I highly recommend the minireview "An Exclusive Contract: Specificity in the Vibrio fischeri-Euprymna scolopes Partnership":" | 19:52 |
| kanzure | http://jb.asm.org/cgi/content/short/182/7/1779 | 19:52 |
| kanzure | "It's awesome. It tells the fantastic story of how V. fischeri and a particular hawaiian squid, E. scolopes, manage to meet and work together," | 19:52 |
| kanzure | "including some detailed theories about how the scolopes' special bioluminescent pockets actively recruit and maintain v. fischeri cultures." | 19:52 |
| jmil | kanzure: nicely done | 19:52 |
| kanzure | hrm? | 19:53 |
| delinquentme_ | kanzure, ooc do you know who most of the ppl in this channel are? | 19:59 |
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| kanzure | delinquentme_: definitely not the newbies | 20:00 |
| kanzure | others, i'd say yes | 20:00 |
| * jmil ducks | 20:01 | |
| kanzure | jmil: what's up? | 20:01 |
| jmil | just waving hi | 20:01 |
| kanzure | ah well have fun | 20:01 |
| jmil | what up wit u? | 20:01 |
| delinquentme_ | hah yeah jmil good choice ... you're in the right spot :D | 20:01 |
| jmil | lol | 20:02 |
| kanzure | another bioluminescence review http://anselmlevskaya.com/papers/bioluminescence.pdf | 20:02 |
| kanzure | he has some other stuff: | 20:02 |
| kanzure | http://anselmlevskaya.com/papers/ | 20:02 |
| kanzure | hah.. http://anselmlevskaya.com/papers/optimism.pdf | 20:03 |
| kanzure | "How unrealistic optimism is maintained in the face of reality" | 20:03 |
| delinquentme_ | jmil, whats your deal / background/ story/ expertise | 20:04 |
| delinquentme_ | dish | 20:04 |
| kanzure | delinquentme_: he's jordan on the diybio list | 20:04 |
| jmil | delinquentme_: im in bioe research | 20:04 |
| jmil | h | 20:04 |
| delinquentme_ | ohh its been forever since i've been on there | 20:04 |
| jmil | ya it's a pretty quiet list | 20:05 |
| delinquentme_ | jmil, sexy | 20:05 |
| delinquentme_ | its awesome | 20:05 |
| jmil | bioe? | 20:05 |
| kanzure | http://groups.google.com/group/diybio/about | 20:05 |
| delinquentme_ | like its really good for when i've got something that doesnt need to be done *this second* | 20:05 |
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| delinquentme_ | bio engineering? yeh hot as hell | 20:05 |
| jmil | oh the diybio list | 20:05 |
| jmil | oh lol | 20:05 |
| jmil | ya bioe FTW | 20:05 |
| delinquentme_ | so what are your daily tools | 20:07 |
| delinquentme_ | is this wetlab work? | 20:07 |
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| jmil | delinquentme_: wet lab and a reprap… :D | 20:16 |
| jmil | highly modified… of course :D | 20:17 |
| delinquentme_ | ... are you printing w cells?? | 20:17 |
| jmil | no that's a horrible idea | 20:17 |
| jmil | i'm printing materials FOR cells. | 20:17 |
| jmil | cells don't like to be printed | 20:17 |
| jmil | there, i said it. | 20:17 |
| jmil | i've been getting flack from cell printer people for my research :D | 20:18 |
| delinquentme_ | fuck what cells want | 20:19 |
| delinquentme_ | they do what we want them to do | 20:20 |
| delinquentme_ | cant you suspend them or something? | 20:20 |
| jmil | lol no they don't do what we want them to do | 20:20 |
| delinquentme_ | something to minimize the trauma they undergo while deposited | 20:20 |
| jmil | people have been saying that for 30 years. where's my printed liver already? | 20:20 |
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| jmil | guess what? it's another 30 years out still lol | 20:20 |
| delinquentme_ | jmil, surely organovo? | 20:20 |
| jmil | lol ya surely | 20:21 |
| jmil | "The stupidest cell is still smarter than the smartest scientist" | 20:21 |
| jmil | best quote evar | 20:21 |
| delinquentme_ | lol | 20:21 |
| delinquentme_ | i think thats a stupid quote | 20:21 |
| jmil | what are you… a cell? | 20:21 |
| delinquentme_ | im trolling you a bit but | 20:21 |
| jmil | lol bring it | 20:21 |
| delinquentme_ | so you're printing out scaffolding? | 20:21 |
| jmil | i need more critiques and feedback | 20:21 |
| jmil | delinquentme_: not exactly | 20:21 |
| delinquentme_ | like whatever we need to do .. | 20:22 |
| jmil | why do you think cell printing is a good idea? | 20:22 |
| delinquentme_ | like i LOVE the cellular watching techniques people have used | 20:22 |
| jmil | besides the media? | 20:22 |
| delinquentme_ | jmil, its not printing its free organs | 20:22 |
| delinquentme_ | so whatever means | 20:22 |
| jmil | what? | 20:22 |
| delinquentme_ | which you'd probably have a better idea | 20:22 |
| delinquentme_ | I mean whatever we need to do for replacement organs | 20:23 |
| kanzure | jmil: i think he's not completing his sentences | 20:23 |
| jmil | kanzure: ya i agree. i'm so confuse | 20:23 |
| jmil | delinquentme_: everyone says they know what that means. but we haven't been able to do "whatever we need to do" for replacement organs for 30-60 years. hell 200 years... | 20:24 |
| jmil | cell printing has not gotten us there | 20:24 |
| jmil | and is irrelevant because we are not assessing viability of each cell AS it's being deposited | 20:24 |
| kanzure | immunosuppressants tend to work on transplants ;) but i think you mean, for non-animal-derivedo rgans | 20:24 |
| jmil | vasculature maps to local cell needs in the body, too. | 20:24 |
| kanzure | *organs | 20:24 |
| kanzure | *tend to sometimes maybe work | 20:24 |
| jmil | kanzure: we can't keep organs alive outside the body for more than a few hours | 20:25 |
| jmil | we wouldn't have organ shortages if we could | 20:25 |
| jmil | we fundamentally are clueless about tissue and organ-level physiology | 20:25 |
| jmil | "put it in a cooler and get on that plane. steve jobs needs a new liver." | 20:25 |
| jmil | that's about the extent of our technology right now | 20:25 |
| jmil | very sad | 20:25 |
| delinquentme_ | hmmm | 20:26 |
| delinquentme_ | more reason why im hesitant about the bio collegiate machine | 20:26 |
| jmil | what? | 20:27 |
| delinquentme_ | like Ive talked to so many people who sit back and are like WAHHHH never happen | 20:27 |
| jmil | lol | 20:27 |
| delinquentme_ | pardon the arrogance and nothing meant at you specifically but fuck that | 20:27 |
| kanzure | delinquentme_: you don't even know what jmil's work is | 20:27 |
| delinquentme_ | everythings always had naysayers | 20:27 |
| jmil | fuck that it's never going to happen? | 20:27 |
| delinquentme_ | blanket statements yes but meh. | 20:28 |
| kanzure | delinquentme_: he's not anti-tissue-culture | 20:28 |
| jmil | lol i never said it's not going to happen | 20:28 |
| kanzure | he's just, doing things differently | 20:28 |
| kanzure | and probably better | 20:28 |
| jmil | and i DO think current techniques will get us there | 20:28 |
| delinquentme_ | you're right kanzure | 20:28 |
| jmil | i just think other technologies will get us there SOONER | 20:28 |
| delinquentme_ | jmil, could i ask about how you guys are approaching it? | 20:28 |
| jmil | ya, we focus on the vasculature | 20:28 |
| jmil | that's the main point anyway | 20:29 |
| jmil | very scalable | 20:29 |
| delinquentme_ | yeah thats the huge issue | 20:29 |
| jmil | i will prove if my way fails before others can pretend to prove their way will work | 20:29 |
| jmil | my way may totally fail | 20:29 |
| delinquentme_ | jmil, is this a undertaking of your own? | 20:29 |
| delinquentme_ | or is this a lab? | 20:29 |
| jmil | but at least i'll be the first to prove that my way failed and we might learn why from it | 20:29 |
| delinquentme_ | ^^^^^ | 20:29 |
| jmil | delinquentme_: ya i work in a research lab | 20:29 |
| jmil | post-doc | 20:30 |
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| delinquentme_ | so you're then essentially attempting to model how the natural vasculature processes hapens | 20:31 |
| delinquentme_ | or more precisely control it | 20:31 |
| jmil | new… see the quote above | 20:33 |
| jmil | i fundamentally believe cells still know more about what they need than we do | 20:33 |
| jmil | that will change over the next 100 years, but we're not there yet | 20:33 |
| jmil | so my goal is to get cells together as fast as possible and perfused as rapidly as possible after encapsulation to mimic perfusion they see in the body | 20:34 |
| jmil | then let them take the lead | 20:34 |
| delinquentme_ | sick art: http://www.andythomas.com.au/Synthetic-Nature | 20:34 |
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| kanzure | wb | 20:35 |
| yashgaroth | goddamn internets | 20:36 |
| jmil | delinquentme_: w0w nice | 20:36 |
| delinquentme_ | ok so jmil you're talking get cells affixed to some substrate .. begin the process of "feeding" them and then let them multiply | 20:42 |
| delinquentme_ | these im assuming are some kind of stem cell? what about the processes within the body needed for particular differentiation | 20:42 |
| delinquentme_ | this is effectively growing organs through the natural process? | 20:43 |
| jmil | delinquentme_: it's accelerated growth in theory | 20:49 |
| jmil | we don't know because we've never done it. yet. :D | 20:49 |
| delinquentme_ | so ive never asked someone about this but what about the white washing pig organs | 20:51 |
| delinquentme_ | like they've got the protein structures there ... and people have built functional hearts through seeding those | 20:52 |
| AlonzoTG | om; http://www.wesolveforx.com/ >> "Imaging the mind's Eye" >> AWESOME!!! | 20:53 |
| kanzure | this is just a set of pictures of faces | 20:54 |
| kanzure | this sucks | 20:54 |
| kanzure | why do i want to look at their pictures | 20:54 |
| AlonzoTG | I'm watching a video on that site. | 20:54 |
| AlonzoTG | =) | 20:54 |
| roksprok | kanzure: i saw your post on diybio about replicating warick's rat brain robot, and was wondering if you ever found a way to get your hands on some 'inexpensive' neural growth factor | 20:56 |
| kanzure | inexpesive.. isn't it like <$100/bottle | 20:57 |
| kanzure | *inexpensive | 20:57 |
| kanzure | another option is to purify it yourself but i don't know if this will end up being cheaper or not | 20:58 |
| yashgaroth | it probably would be, if super-high quality isn't a requirement | 20:58 |
| roksprok | can you use the stuff in the capsules? | 20:59 |
| roksprok | I'm only finding stuff like this: http://www.promega.com/products/cell-signaling/growth-factors/nerve-growth-factor_-2_5s_-murine/ | 20:59 |
| kanzure | search the big chem catalogs | 20:59 |
| kanzure | sigma aldrich, merck, carolina, fischerprice | 20:59 |
| jmil | delinquentme_: a lot of people are trying that. but there's zero control. and cells get damaged when seeded from the vasculature into the interstititium. it's so poorly controlled, though, that they won't be able to study it. every single construct is highly different... | 21:00 |
| yashgaroth | I should add, making your own NGF is only cheaper if you need a lot of it and already have the equipment | 21:01 |
| kanzure | *shrug* cell culturing and purification stuff is good to have if you're doing lots of projects | 21:01 |
| yashgaroth | even if you're not doing any projects, it's good to have around | 21:01 |
| kanzure | ? | 21:02 |
| roksprok | kanzure: good point, i end up spending way too much money on this kind of stuff tho | 21:02 |
| yashgaroth | you never know when you'll need protein purification equipment around, active project or no | 21:02 |
| delinquentme_ | jmil, seeded from the vasc >> insterstitium? | 21:04 |
| delinquentme_ | jmil, actually we need to chat about this indepth another time :D | 21:04 |
| delinquentme_ | thanks for being here :D | 21:04 |
| jmil | coolio | 21:06 |
| jmil | i'm usually on a couple times a week | 21:06 |
| roksprok | kanzure: would a company like merk ship to a home address? | 21:07 |
| kanzure | it depends.. there's lots of diybio threads about this and the results | 21:07 |
| roksprok | they say 'price availible on request' so it doesn't seem like an easy transaction | 21:07 |
| kanzure | if you can't get them to do that, set up a business at your address or figure out the zoning laws | 21:07 |
| roksprok | k i'll search | 21:07 |
| kanzure | 'price available on request' is usually a phone call | 21:07 |
| yashgaroth | also some companies, e.g. sigma, straight up won't ship to home addresses, business or no | 21:08 |
| kanzure | 'price available on request' is the bane of my existence | 21:09 |
| kanzure | i should setup a site to route around 'price available on request' | 21:09 |
| kanzure | people should just type in the prices that were 'available on request' | 21:10 |
| delinquentme_ | i've got an entity if you really need one roksprok | 21:10 |
| delinquentme_ | :D | 21:10 |
| roksprok | delinquentme_: nice, i may take you up on that | 21:10 |
| Mokbortolan_ | well, they want to talk to you | 21:10 |
| kanzure | Mokbortolan_: but i don't | 21:11 |
| Mokbortolan_ | it might be that you really need product X, but were looking at product Y | 21:11 |
| kanzure | availablebyrequest.com is available | 21:11 |
| delinquentme_ | lol | 21:11 |
| Mokbortolan_ | they wouldn't want you to be turned away from product X because you thought product Y's price was too high | 21:11 |
| kanzure | well they should list their prices then | 21:11 |
| Mokbortolan_ | silly consumer, you don't know *what* you need! | 21:11 |
| Mokbortolan_ | just let them tell you what you need | 21:12 |
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| delinquentme_ | youu dont want an ipost shuffle | 21:16 |
| delinquentme_ | you want a ac book pro | 21:17 |
| * delinquentme_ slow nod | 21:17 | |
| delinquentme_ | checking out! | 21:34 |
| delinquentme_ | toodles! | 21:34 |
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| kanzure | good night moon | 23:21 |
| kanzure | gedankenstuecke: nice domain name | 23:35 |
| utopiah_ | Solve for X: Adrien Treuille on collaborative science http://www.youtube.com/watch?v=A-CCEy3u2WM | 23:37 |
| Stee| | Hmm | 23:39 |
| Stee| | tomorrow's todo | 23:39 |
| Stee| | enable latex on site, fix blog options, rss feed to site | 23:39 |
| --- Log closed Tue Feb 07 00:00:59 2012 | ||
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