--- Log opened Thu Mar 01 00:00:32 2012 | ||
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strangewarp | ...I didn't expect Boingboing commenters, en masse, would have such readily available proofs that transhumanism is false and silly. | 02:53 |
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strangewarp | Need to just.. stop reading blog comments. They tend to be infuriating | 02:53 |
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foucist | strangewarp: orly, what are they saying? | 04:07 |
foucist | which part of transhumanism are they attacking anyways? isn't transhumanism an umbrella term? heh | 04:07 |
strangewarp | Yeah, basically they were railing against the stupidity of that thing they thought transhumanism is: you know, with the singularity and the rapture rhetoric and whatnot | 04:39 |
joshcryer | It's contrasted with a distopian future. | 04:42 |
joshcryer | People are pessimists, the negativity fed to them on a regular basis. | 04:42 |
strangewarp | indeed | 04:42 |
joshcryer | Don't get me wrong, I can be a major alarmist. | 04:42 |
joshcryer | But that only makes it more compelling to seek a better future. | 04:42 |
joshcryer | The article if foucist is interested: http://boingboing.net/2012/02/29/a-pessimist-and-an-optimist-ta.html | 04:43 |
joshcryer | (Don't have time to watch both videos now so it being in the log is also a plus.) | 04:43 |
strangewarp | (Also, I now feel a little silly for getting mad at a couple blog comments, especially since I vented elsewhere instead of replying to them directly, but it was before my daily coffee so meh) | 04:44 |
joshcryer | I don't see much substance here, in any event. | 04:47 |
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splicer | ns identify smurfpunk | 06:24 |
vrs | must... resist | 06:26 |
splicer | do ;) | 06:26 |
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vrs | ehehe | 06:27 |
vrs | sorry | 06:27 |
vrs | update your pw :) | 06:27 |
splicer | hmmm... wtf is <key> ? | 06:30 |
vrs | help setpass | 06:34 |
vrs | set your email first I guess | 06:34 |
splicer | solved it | 06:34 |
splicer | thanks for resisting.... was sweating there | 06:35 |
vrs | actually I didn't resist | 06:48 |
vrs | I ghosted you once | 06:48 |
splicer | noticed that | 06:48 |
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archels | so this build has been sitting for hours at | 08:47 |
archels | [100%] Building CXX object dolfin/swig/CMakeFiles/_cpp.dir/dolfinPYTHON_wrap.cxx.o | 08:47 |
archels | using 100% CPU and thrashing my HDD | 08:47 |
archels | Do I assume it's doing something useful, or do I kill it and start an incredibly tedious process of troubleshooting? | 08:47 |
kanzure | magic eight ball says yes | 08:58 |
kanzure | put it into the foreground and zombie it | 08:58 |
kanzure | ...background | 08:59 |
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archels | grm, any way I could monitor its filesystem I/O? | 09:04 |
archels | (Debian) | 09:04 |
ThomasEgi | iotop ? | 09:12 |
archels | Hm, I guess I'd like a combination of iotop and lsof. | 09:17 |
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archels | alright fuck it, this is stupid. | 09:22 |
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delinquentme | KNOW WHICH LANGUAGES TO USE FOR WHAT TASKS | 10:36 |
delinquentme | ^^ | 10:36 |
delinquentme | ... on being irreplaceable .. thoughts? comments? | 10:36 |
ThomasEgi | spylanguage? :D | 10:42 |
ThomasEgi | asm? | 10:42 |
delinquentme | ThomasEgi, so I mean like you shouldn't be doing massive processing in something like Ruby | 10:44 |
delinquentme | drop that into a CRuby instance .. IDK it just seems like the # of programming languages is on a steady upward trend | 10:45 |
delinquentme | sooo use them accordingly | 10:45 |
ThomasEgi | hm. my combination of python. and c/c++ worked out very well so far | 10:46 |
eudoxia | everyone's out to create the Programming Language to End All Programming Languages | 10:46 |
ThomasEgi | python for all the slam-together stuff with fast prototyping speed, and doubles as script language for automation. | 10:46 |
ThomasEgi | and c for microcontrollers. and c++ for desktop when you really need sped | 10:46 |
ThomasEgi | *speed | 10:46 |
kanzure | pfft clearly we should be writing all of our microcontroller code in haskell | 10:48 |
delinquentme | true and prototyping speed is a consideration | 10:50 |
ThomasEgi | bout 90% of my code is python tho. | 10:51 |
delinquentme | but in the credo of doing shit ... it seems that outside of a job environment ( maybe in some ) you'd want a few tools | 10:52 |
ThomasEgi | not sure what you intend to say. but python is a very powerful tool, especially since there are countless libraries with pythonbindings out there | 10:55 |
ThomasEgi | from interfacing to serial ports , over making SIP calls, up to creating 3d games. pretty much nothing that wouldnt be possible with python. | 10:56 |
delinquentme | true ^ | 11:03 |
delinquentme | stilla theory in testing :D | 11:04 |
ThomasEgi | well at least for me it does a wonderful job | 11:05 |
* delinquentme skrilly lovemaking music | 11:19 | |
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delinquentme | MEH i think ec2 is .. lagging? | 11:37 |
sylph_mako | http://www.bbc.co.uk/news/health-17177251 I just found a motivation to start examining the genes of my friends/mates/self. | 11:38 |
sylph_mako | Too valuable. | 11:38 |
delinquentme | ? thats about excercise? | 11:38 |
delinquentme | ohh ic ic | 11:38 |
sylph_mako | [a gene marker that indicates an ability to get fit off of but 3 minutes of intense exercise a week.] | 11:39 |
sylph_mako | [as opposed to wasting serveral hours of your time.] | 11:40 |
delinquentme | so you're then going to aquire the genes how? | 12:05 |
sylph_mako | I'm not. I'm going to commit eugenics. | 12:14 |
sylph_mako | I know it's kind of silly. | 12:15 |
sylph_mako | Considering how little time there is to make an impact. | 12:15 |
sylph_mako | Oh you mean the samples? | 12:15 |
delinquentme | sylph_mako, umm so wait | 12:19 |
delinquentme | haha you're picking out your girlfriend in this manner? | 12:19 |
delinquentme | like who am I to tell anyone how to do that but ... | 12:19 |
kanzure | what? | 12:20 |
kanzure | i think sylph_mako was making a joke about killing everyone | 12:20 |
ThomasEgi | oh. if he really intends to do so. i have i wishlist with people of top-priority ;) | 12:21 |
sylph_mako | hahaha, It was more making a joke about how eugenics sounds like genocide to most people. | 12:23 |
kanzure | eugenics basically is genocide | 12:23 |
sylph_mako | What I'm hoping is that there's a human breeding program going on somewhere. | 12:23 |
sylph_mako | Oh I suppose it is. | 12:24 |
kanzure | animal husbandry/breeding sounds tremendously more descriptive | 12:24 |
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sylph_mako | Mind that it's also the opposite. | 12:24 |
sylph_mako | \converse | 12:25 |
kanzure | see, i didn't know if you meant "eugenics as in kill all the people" or "eugenics as in something about genetics generically" | 12:25 |
kanzure | i guess this is like hackers vs. hackers | 12:25 |
Stee| | eugenics can be comprised of three different degrees, more or less | 12:25 |
kanzure | except nobody supports using the word 'eugenics' for anything | 12:25 |
Stee| | 1) Encourage good genes to breed | 12:25 |
delinquentme | dogs == longest running human lead eugenics experiment in the entirety of history | 12:25 |
sylph_mako | No no no no no I just mean to sterilize the people. | 12:26 |
Stee| | 2) stop bad genes from breeding (The US did this) | 12:26 |
Stee| | (which is what sylph_mako suggested) | 12:26 |
Stee| | 3) Murder people with bad genes | 12:26 |
Stee| | I support #1. | 12:26 |
kanzure | who defines good | 12:26 |
kanzure | see, this is the problem that WTA ran into | 12:26 |
sylph_mako | Stee|... I was sugguesting (1) more than (2).. | 12:26 |
kanzure | they wanted to do this political thing about defining good | 12:26 |
Stee| | you can find the minimum gradient of bad | 12:26 |
sylph_mako | but with the current population.. you'd at least have to do both 1 and 2 at once. | 12:27 |
kanzure | i just strongly discourage you from using the word 'eugenics' | 12:27 |
kanzure | please just say 'murder everyone' if that's what you mean | 12:27 |
sylph_mako | is human breeding a clean enough term? | 12:27 |
Stee| | but that's not what most people mean with it, kanzure | 12:27 |
kanzure | sylph_mako: no you have to also explain what you mean | 12:28 |
Stee| | nazi eugenics is not the only form of eugenics | 12:28 |
kanzure | sylph_mako: "human breeding" could mean "forced human breeding labor camps" | 12:28 |
sylph_mako | the maturation of the human species? | 12:28 |
kanzure | or you could simply mean "i want to fuck up my genes before injecting my genomes into embryos, yo" | 12:28 |
kanzure | the hell does that mean? | 12:29 |
Stee| | what about 'encouragement of people with specific genes breeding' | 12:29 |
kanzure | sounds fascist | 12:29 |
Stee| | nah, that would be sterilization | 12:29 |
sylph_mako | it's kind of a dune quote. | 12:29 |
kanzure | i also don't see why you would force people to breed, in this day and age | 12:29 |
kanzure | since we have the bioinformatics anyway | 12:30 |
kanzure | fuck karyotype charts | 12:30 |
kanzure | well, wait | 12:30 |
kanzure | what's the chart that takes into account your ancestry | 12:30 |
kanzure | erm, the one that people use for determining an nth-generation trait in their family | 12:31 |
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Juul | kanzure, seen this: http://shapesmith.net/ ? | 12:31 |
kanzure | Juul: yeah | 12:31 |
kanzure | that's ben nortier | 12:31 |
Juul | ah | 12:31 |
kanzure | he has opencascade wired up | 12:31 |
kanzure | and then has a javascript client transmit shit back to his server | 12:31 |
kanzure | to do the boolean operations | 12:31 |
Juul | oh | 12:31 |
Juul | :) | 12:31 |
kanzure | then he tessellates and sends it to the client for webgl rendering | 12:31 |
kanzure | he made a peculiar choice for the backend.. it was something like lisp or scala | 12:32 |
kanzure | erl | 12:33 |
delinquentme | working under the gun | 12:33 |
* delinquentme feels good man | 12:33 | |
kanzure | erlang, right. | 12:33 |
kanzure | i knew it was something | 12:33 |
delinquentme | i think you're confusing euthanasia with eugenics kanz | 12:34 |
delinquentme | eugenics is simply selective breeding no? | 12:34 |
Stee| | depending on what country did it | 12:34 |
delinquentme | like only talking to the hot girls @ the bar | 12:34 |
delinquentme | haha ok context yes | 12:35 |
Stee| | nazi germany also did sterilization | 12:35 |
kanzure | delinquentme: no eugenics is not "simply selective breeding" | 12:35 |
kanzure | it means a lot of things | 12:35 |
delinquentme | anyone want to take bets whether im going to break this small EC2 instance? | 12:35 |
delinquentme | im thinking i will | 12:35 |
Stee| | however, it doesn't necessarily imply genocide or murder at all | 12:35 |
delinquentme | Eugenics is the "applied science or the bio-social movement which advocates the use of practices aimed at improving the genetic composition of a population", usually referring to the manipulation of human populations | 12:35 |
sylph_mako | If you're selecting against a gene, I think that would be genocide. | 12:35 |
sylph_mako | It's probably not going to be particularly racially focal. Or violent in any way. | 12:36 |
delinquentme | sure if you want to add some kind of sinister context feel free to | 12:36 |
eudoxia | people select against genes all the time | 12:36 |
delinquentme | perhaps in the vernacular use | 12:36 |
Juul | kanzure, do you know anything about homomorphic encryption? | 12:36 |
delinquentme | eudoxia, exactly! | 12:36 |
kanzure | Juul: no | 12:36 |
eudoxia | when they don't talk to the ugly girls at the bar I guass | 12:36 |
kanzure | haha yes it's well known you can twist words to mean whatever | 12:36 |
kanzure | but mostly when you say 'eugenics' to someone they think of government-intervention for things like sterilizing large populations | 12:37 |
kanzure | or killing large populations of people | 12:37 |
delinquentme | eudoxia, hahaha | 12:37 |
sylph_mako | Because they're fucking dogs. | 12:37 |
delinquentme | #win | 12:37 |
sylph_mako | Judgemental, traumatized dogs. | 12:37 |
Stee| | yes, but we're not talking to normal people here are we | 12:37 |
kanzure | yes you can say "talking to the hot girls at bars is eugenics" | 12:37 |
kanzure | but you could also say "it's genetics" | 12:37 |
kanzure | so fucking what? | 12:37 |
delinquentme | Stee|, <<<<< | 12:37 |
eudoxia | I dunno | 12:37 |
kanzure | Stee|: i'm saying "eugenics" is not a high-information-bandwidth word | 12:37 |
Stee| | genetics is an even worse one | 12:37 |
kanzure | say something more meaningful.. | 12:37 |
* delinquentme thinks we're regressing | 12:38 | |
delinquentme | r/askshityscience | 12:38 |
kanzure | delinquentme: we regressed the moment someone brought up the god damn word 'eugenics' | 12:38 |
delinquentme | :D | 12:38 |
delinquentme | semantics | 12:38 |
Stee| | nah, I think everyone here is fine with the word but you kanzure :P | 12:38 |
delinquentme | nah like ill agree w kanzure | 12:38 |
delinquentme | its like a loaded term | 12:38 |
delinquentme | but thats within societal context | 12:39 |
delinquentme | annnd most of society is well _______ | 12:39 |
delinquentme | you fill in the blank | 12:39 |
Stee| | it's a loaded term to most people, but everyone here got what was meant in sentence context | 12:39 |
delinquentme | ^^^ | 12:39 |
kanzure | not really | 12:39 |
kanzure | i still don't know if you're pro-killing-people | 12:39 |
sylph_mako | No why the hell would that be a good idea. | 12:39 |
Stee| | I clarified it like 3 times? | 12:39 |
Stee| | goddamn, humanist is in the name dude | 12:39 |
kanzure | Stee|: you already said "encouraging certain people to breed".... which is easily implemented as "discouraging everyone else" | 12:40 |
Stee| | note that I listed three levels, of which discouraging was the second one. | 12:40 |
Stee| | in addition, discouraging is STILL different from killing people | 12:40 |
kanzure | why can't you just say "i prefer to be in control of my own genes, thanks" | 12:40 |
eudoxia | "discouraging" is rather vague | 12:41 |
kanzure | instead of calling it eugenics | 12:41 |
kanzure | eudoxia: exactly | 12:41 |
Stee| | what if I'm talking about on a societal level? | 12:41 |
Stee| | and not about my own genes? | 12:41 |
kanzure | Stee|: that's the bad form of eugenics :P | 12:41 |
kanzure | the one where you impose your will on everyone else | 12:41 |
Stee| | which, AGAIN, is what I think sylph_mako was talking about | 12:41 |
Stee| | don't make it law, offer incentives :P | 12:41 |
kanzure | see? you said you disagree with the popular notion of 'eugenics' | 12:42 |
kanzure | but these statements make me think you do *not* disagree | 12:42 |
Stee| | popular view of eugenics involves murder and sterilization | 12:42 |
kanzure | this is why we should be more careful with words | 12:42 |
Stee| | I explained this above | 12:42 |
Stee| | you are the one having issues here :P | 12:42 |
kanzure | Stee|: specifically they involve murder, sterilization and government intervention | 12:42 |
Stee| | I got what sylph_mako was saying | 12:42 |
kanzure | you just said "incentivizes" - that's government intervention on its population again | 12:42 |
Stee| | yes, I'm okay with this | 12:43 |
kanzure | how is that any different from the form that you purportedly claim to me that you disagree with | 12:43 |
Stee| | because one is murder and sterilization and one is not | 12:43 |
Stee| | keep in mind I'm not a libertarian | 12:43 |
kanzure | the murder/sterilization is a political issue, iirc | 12:43 |
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kanzure | i.e. why should the government kill its citizens | 12:44 |
Stee| | it's an ethical issue | 12:44 |
sylph_mako | kanzure, but it's NOT my will I want to impose. I don't want to be the guy making the decisions on what to breed for. Ideally it wouldn't even be a guy, it would be a process. | 12:44 |
kanzure | so my point is, creating incentives on top of a population that you are ruling, without their consent, sorta goes against the politis thing | 12:44 |
kanzure | *politics | 12:44 |
kanzure | now! if you want to start a new government and a new population | 12:44 |
Stee| | but if I don't have a political issue, but an ethical issue, then it's fine | 12:44 |
kanzure | where you impose your genetic will and design | 12:44 |
sylph_mako | yes! | 12:44 |
kanzure | then go right ahead | 12:44 |
kanzure | but fuck you if you touch my genes without my authorization | 12:45 |
sylph_mako | I so will. | 12:45 |
sylph_mako | [go right ahead] | 12:45 |
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Stee| | kanzure: I also believe in forced retroviral removal of genetic disease laden genes, and forced immortality | 12:45 |
kanzure | yeah, so again, you *do* agree with the populist notions of eugenics | 12:46 |
ThomasEgi | believe is good. engineering is better. | 12:46 |
Stee| | kanzure: Neither of these involve murder or sterilization | 12:46 |
Stee| | jesus christ | 12:46 |
kanzure | "forcing people to change against their will" is a pretty firm axiom of the popular notion of eugenics | 12:46 |
Stee| | no, the murder and sterilization parts are the big thing | 12:46 |
kanzure | because... that's against their will | 12:46 |
Juul | Stee|, forced immortaility? your a scary motherfucker | 12:47 |
kanzure | lots of people support i.e. assistive suicide | 12:47 |
Juul | *you're | 12:47 |
Stee| | Juul: I support forced posthumanism in general, but not if it involves uplifting :P | 12:47 |
eudoxia | what | 12:47 |
Stee| | err, uploading | 12:48 |
Stee| | rather | 12:48 |
delinquentme | suicide = the point where humans should intervene and help that kid out | 12:48 |
eudoxia | oh right | 12:48 |
delinquentme | positive psychology is real shit | 12:48 |
delinquentme | or more concrete .. positive focus / distractions from that bad stimulus | 12:48 |
Juul | forced consciousness seems like a scary proposition to anyone with any kind of imagination | 12:49 |
ThomasEgi | delinquentme, arent there countries that have death sentence on attempted suicide? | 12:49 |
kanzure | so again, i think the scary form of eugenics is the same one that Stee| likes | 12:49 |
kanzure | even though Stee| does not support murder and sterilization | 12:49 |
Stee| | kanzure, unfortunately you're wrong | 12:49 |
kanzure | so wait | 12:49 |
Stee| | because the murder and sterilization part is bigger than the gov part in most peoples minds | 12:49 |
delinquentme | ThomasEgi, lolol people | 12:49 |
delinquentme | jesus we're all so fucking ignorant | 12:50 |
kanzure | Stee|: ok so you claim that popular eugenics is scary not because it's a forced thing, but because..? | 12:50 |
delinquentme | seriously we're going to look back at pre life extension times | 12:50 |
Stee| | OF DEATH AND MUTILATION | 12:50 |
delinquentme | and be like WTF .. how did they even live | 12:50 |
Juul | delinquentme, at least some of us realize it :) | 12:50 |
kanzure | Stee|: ok.. we support abortions, that's death... who cars? | 12:50 |
kanzure | *cares | 12:50 |
Stee| | most people don't consider it death tho | 12:50 |
delinquentme | Juul, =] im glad I've got friend who are of sound mind | 12:50 |
Stee| | (I'm not pro-abortion, I'm pro-putting fetuses into artificial wombs) | 12:50 |
eudoxia | I'm pro putting blastulae in liquid nitrogen until somebody gives a fuck | 12:51 |
kanzure | ok so you claim that eugenics is scary simply because murder is not a friendly concept? | 12:51 |
Stee| | pretty much, and that's what people associate with it | 12:51 |
Stee| | that and nazis | 12:51 |
Stee| | *and sterilization, dudes are protective of their sperm | 12:52 |
kanzure | ok i posit that the popular notion of eugenics is 'scary' because governments/authorities | 12:52 |
Juul | delinquentme, you're sane?! | 12:52 |
* ThomasEgi checks the sane-o-meter in the channel.. | 12:52 | |
Stee| | empty, ThomasEgi | 12:52 |
ThomasEgi | uh.. it indicates chilling levels indeed | 12:53 |
kanzure | why would i want to allow you to control whether or not i build offspring | 12:53 |
Stee| | note that I said incentive | 12:54 |
delinquentme | Juul, its a stretch man =] | 12:54 |
delinquentme | hanging by thread | 12:55 |
sylph_mako | Because limits on the individuals' reproduction is an easy way to ant-style altruism? I havn't read any Rand yet, and I'm not american[in fact I live in one of the least corrupt countries in the world], so there's probably a lot I don't understand about your feelings about government's power. | 12:57 |
Stee| | (I'm not fond of ant style altruism, and I agree with incentivizing certain genetic combinations for other reasons) | 12:58 |
Juul | i think people aren't wearing enough hats | 12:59 |
sylph_mako | Stee|, I havn't come across a clearer models of a stable super-altruistic evolutionary strategy. It just always seems like there's some limit on breeding whenever groups get social. Sometimes they're entirely mental, sometimes they're pheremonal castration. | 13:01 |
Stee| | I dislike it because I'm a greedy bastard and want to ditch all y'all | 13:02 |
Stee| | anyway, airport, bbl | 13:02 |
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* delinquentme so many angry tweets! | 13:05 | |
delinquentme | TITS! | 13:06 |
delinquentme | parser runs on a ec2 large | 13:06 |
delinquentme | tiddayssss | 13:06 |
delinquentme | no! ec2 small 32 bit | 13:06 |
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delinquentme | LOLLLL causing more hell on twatter | 14:29 |
delinquentme | who the fuck becomes a bioethicist anyways | 14:29 |
kanzure | http://www.npr.org/blogs/krulwich/2012/02/24/147367644/six-legged-giant-finds-secret-hideaway-hides-for-80-years?sc=fb&cc=fp | 14:38 |
kanzure | didn't even realize this was npr | 14:38 |
delinquentme | kanzure, you're not tweeting | 14:39 |
delinquentme | we're here trying to change the world! | 14:40 |
delinquentme | step up your twattering! | 14:40 |
uniqanomaly_ | delinquentme: its like with religious people | 14:41 |
uniqanomaly_ | if you could reason with them they wouldnt be religious | 14:41 |
uniqanomaly_ | humble theory about those bioethics fucks | 14:42 |
uniqanomaly_ | ^^ | 14:42 |
delinquentme | https://twitter.com/#!/delinquentme/status/175346930061295616 | 14:42 |
delinquentme | dey see me trollin | 14:42 |
uniqanomaly_ | also humanist = can't do science | 14:44 |
uniqanomaly_ | but its obvious | 14:44 |
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delinquentme | humanist? | 14:46 |
delinquentme | humanity*? | 14:46 |
kanzure | delinquentme: to download a zip from the command line just use wget or curl.. | 14:46 |
delinquentme | yeah wget did it | 14:47 |
delinquentme | i gotta figure how to setup the ec2 env for the API nao | 14:47 |
uniqanomaly_ | dammit, I meant humanities | 14:55 |
uniqanomaly_ | like in: whats one's excuse when they can't fill tax forms? - i'm a humanities major | 14:58 |
delinquentme | lol | 15:01 |
delinquentme | conscious objector? | 15:02 |
delinquentme | its ANOTHER ONE BOWM. BROWWWWow! | 15:04 |
delinquentme | guh | 15:04 |
delinquentme | when I live to b e 1000 im going to be a DJ | 15:05 |
delinquentme | im just saying .. you guys are all invited to my shows | 15:05 |
delinquentme | why do I want to live longer? because there WAY more cool shit this life has to offer than we can fit into a "normal" life span :D | 15:05 |
kanzure | you're preaching to the choir | 15:06 |
kanzure | this is the silliest place to preach about the benefits of life extension and immortality | 15:07 |
kanzure | also you shouldn't wait that long to start djing :x | 15:07 |
kanzure | klafka has some experience in this department, i hear | 15:07 |
delinquentme | yeah I was thinking that :D | 15:10 |
splicer | delinquentme: you want to live longer because there is a selection pressure against people who get themselves killed before they spawn. | 15:10 |
delinquentme | whut? | 15:11 |
delinquentme | lol | 15:11 |
delinquentme | that almost makes sense? | 15:11 |
uniqanomaly_ | delinquentme: yeah why wait, you should make some transhuman dubstep right now | 15:11 |
delinquentme | hah! | 15:11 |
delinquentme | I'm programming ec2 .. while absorbing the nuances *studying* dubsteps | 15:12 |
delinquentme | love you guys so fucking Xcore | 15:12 |
delinquentme | ( hardcore ) :P | 15:14 |
sylph_mako | Truth | 15:14 |
uniqanomaly_ | delinquentme: or you could just convert skrillex and others to transhumanism, they could put some subliminal stimuli shit in future works | 15:14 |
uniqanomaly_ | haha | 15:14 |
delinquentme | ^^^^^^^^^^^^^^ hot | 15:14 |
uniqanomaly_ | transhuman conversion taskforce | 15:19 |
delinquentme | some quote about not telling someone to get the bricks and the mortar .. but instead teaching them how to yearn for what is to come? | 15:20 |
delinquentme | like the evolution of music is nuts .. give that shit 200 years .. no man I cant even BEGIN to take a stab | 15:20 |
sylph_mako | Why does dubstep seem like a necessary step forward to me. It's like I heard traces of it in the music of the past and thought; we need to do more of That, whatever it is. If only we knew how. | 15:25 |
sylph_mako | A lot of things went like that. | 15:27 |
delinquentme | sylph_mako, I like the part where we've got music w tangible fury in it .... and mainstream is adopting it | 15:27 |
delinquentme | that blows my mind | 15:27 |
sylph_mako | genres/ | 15:27 |
delinquentme | like he got 3 grammys | 15:27 |
delinquentme | and hes like a metalhead convert .. its just nuts | 15:27 |
delinquentme | human unity? << just speculation | 15:27 |
sylph_mako | furious has a lot of meanings. "Furious violining". Pretty sure that was always a revered thing. | 15:28 |
uniqanomaly_ | hmm, algos actually evolving music would be crazy | 15:29 |
delinquentme | ^^^ | 15:29 |
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delinquentme | some guy made a shell program to do just that | 15:29 |
delinquentme | sylph_mako, paganinni | 15:29 |
delinquentme | revered as being possessed for his skills | 15:30 |
sylph_mako | Anyone used electric sheep? It evolves ridiculous fractal screensavers based on upvotes and downvotes from every user. | 15:30 |
sylph_mako | If you could do a similar thing for music.. you could make a station based on that shit. | 15:31 |
uniqanomaly_ | http://darwintunes.org/evolve-music | 15:31 |
delinquentme | machines. | 15:32 |
sylph_mako | omg | 15:34 |
uniqanomaly_ | http://tones.wolfram.com/ :< | 15:34 |
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uniqanomaly_ | http://www.sadistic.pl/pics/2_d8e5544669aa.jpg | 16:58 |
uniqanomaly_ | :D | 16:58 |
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delinquentme | http://www.fightaging.org/archives/2012/03/more-background-on-the-russia-2045-initiative.php | 18:28 |
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kanzure | hi yashgaroth | 18:35 |
kanzure | saw the email. | 18:35 |
yashgaroth | ah yes, thanks for crosspostin' | 18:35 |
yashgaroth | I'm thinking of posting it biohack, but they're a little insane over there...not necessarily in a bad way though | 18:35 |
yashgaroth | *to/on biohack | 18:36 |
kanzure | i'm a little surprised nobody has complained that you're destroying humanity on the diybio list yet | 18:40 |
kanzure | there used to be complaints about our somewhat more niche interests | 18:41 |
kanzure | glad it's gone down :) | 18:41 |
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kanzure | the longevity groupies are probably helping there | 18:41 |
yashgaroth | I'm telling you, all the founders of DIYbio Seattle were big fans of transhumanism | 18:42 |
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joshcryer | How is he destroying humanity? (I enjoy drama with the best of 'em.) | 19:01 |
kanzure | joshcryer: oh just bogus bullshit | 19:17 |
kanzure | don't pay attention to those people | 19:17 |
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sylph_mako | This story made me happy https://en.wikipedia.org/wiki/Repository_for_Germinal_Choice but it's regrettably concluded. | 19:34 |
kanzure | yashgaroth: what's wrong with blood injections, again? | 19:39 |
kanzure | zacharycohn: hey how do you know nathan? | 19:39 |
yashgaroth | injections of plasmid, protein, or other blood? | 19:40 |
kanzure | i was thinking protein | 19:40 |
yashgaroth | I have seriously considered it...for follistatin, you want to at least try to limit the off-target effects | 19:41 |
yashgaroth | but a myostatin propeptide-Fc fusion would be a strong candidate | 19:41 |
kanzure | fc? | 19:43 |
kanzure | so wasn't one of the clinical trials for a propeptide? | 19:43 |
yashgaroth | that one never made it to trials | 19:43 |
kanzure | hrm. i'm not misremembering am i? | 19:43 |
kanzure | i know follistatin did | 19:43 |
yashgaroth | Fc is antibody backbone, it's added to increase half-life from a few hours to a few weeks | 19:43 |
yashgaroth | follistatin, anti-myostatin monoclonal, and acvr2b fc fusion have all been in trials | 19:44 |
yashgaroth | Fc fusion also makes it a fuckton easier to produce | 19:44 |
kanzure | my knowledge of trial results is current up to 2009 | 19:44 |
kanzure | or, rather, "current and fuzzy because it was 2009" | 19:44 |
yashgaroth | follistatin's the only one currently trialing, I think they're injecting the AAV now-ish | 19:45 |
yashgaroth | acvr2b was a couple years ago I think | 19:45 |
zacharycohn | kanzure: haha, yeah! How do you know nathan? | 19:46 |
kanzure | this conversation needs more clinicaltrails.gov links | 19:46 |
kanzure | zacharycohn: he hangs out in here | 19:46 |
kanzure | what you talkin about | 19:47 |
yashgaroth | folli: http://clinicaltrials.gov/ct2/show/NCT01519349?term=follistatin&rank=1 | 19:47 |
zacharycohn | kanzure: haha, really? What's his handle? | 19:47 |
kanzure | nmz787 (he seems to be off irc at the moment) | 19:47 |
yashgaroth | acvr2b was http://clinicaltrials.gov/ct2/show/NCT01099761?term=acvr2b&rank=4 | 19:48 |
yashgaroth | I'm chatting with nmz787 in the diybio topic right now, so he's online-ish | 19:48 |
kanzure | yashgaroth: yeah he's on jabber | 19:48 |
zacharycohn | kanzure: yeah, he and i worked together when we went to school | 19:48 |
kanzure | hmmm suspicious | 19:48 |
zacharycohn | How did you know we knew each other? | 19:49 |
kanzure | i checked out his facebook profile to figure out how the fuck to spell bhowmik | 19:49 |
zacharycohn | haha | 19:49 |
kanzure | and you're on there | 19:49 |
zacharycohn | tadaaa | 19:50 |
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nmz787 | zach, /YOU/ hang out here? | 19:53 |
kanzure | zacharycohn: there we go | 19:53 |
zacharycohn | nmz787: :) | 19:53 |
nmz787 | small world, I guess | 19:53 |
nmz787 | lol | 19:53 |
zacharycohn | I mostly hang out on #startups | 19:53 |
zacharycohn | but i started hanging out here about a week ago | 19:53 |
nmz787 | yeah so kanzure is the collaborator i am looking to do the synbio startup with | 19:53 |
zacharycohn | no matter what you do don't trust him | 19:54 |
zacharycohn | >.> | 19:54 |
nmz787 | he's kind of a jerk of all trades | 19:54 |
kanzure | aw shucks | 19:54 |
zacharycohn | hahah | 19:54 |
kanzure | that's how i know you really care about me | 19:54 |
nmz787 | he can transcribe lectures in real-time though | 19:55 |
kanzure | nmz787: inkscape still making you its bitch? | 19:55 |
nmz787 | i think he's a mechanical turk for google | 19:55 |
zacharycohn | kanzure: <3 | 19:55 |
nmz787 | kanzure: its coming along | 19:55 |
nmz787 | kanzure: slowly | 19:55 |
nmz787 | zach, do you still have that army backpack? | 19:58 |
zacharycohn | nmz787: hellll yeah | 19:59 |
nmz787 | you're in WA now? | 20:00 |
zacharycohn | That hookup was like, one of the best parts of working at FAST | 20:00 |
zacharycohn | Yep, in Seattle. | 20:00 |
yashgaroth | oh hey I'm from seattle, good choice | 20:00 |
nmz787 | did you go to BANFF film fest? | 20:00 |
zacharycohn | yashgaroth: oh yeah? Where? I'm in Belltown | 20:00 |
nmz787 | we just had it here like a week ago i think | 20:00 |
zacharycohn | nmz787: uuugghhh no. I tried but it sold out within a day. | 20:00 |
zacharycohn | Then I tried to get a press pass | 20:01 |
yashgaroth | I lived by the UW for like 15 years, but I live in san diego now for work | 20:01 |
zacharycohn | but they couldn't do it. They said they had already exceeded the number of people legally allowed in the building. | 20:01 |
zacharycohn | (I'm not with press, but they didn't know that... :p) | 20:01 |
nmz787 | zacharycohn: ohhh, it was pretty sweet, I went to all 3 (3 hr) sessions here | 20:01 |
zacharycohn | man, I really wanted to go. | 20:01 |
zacharycohn | next time! | 20:01 |
nmz787 | there was some sick urban skiing | 20:02 |
zacharycohn | yashgaroth: Ah, nice. I just moved here about 2 years ago | 20:02 |
yashgaroth | heh I moved to SD 2 years ago, though I do hope to move back when my current company gets bought or goes under | 20:02 |
zacharycohn | good exit strategy. | 20:02 |
yashgaroth | good jobs in biotech are hard to find | 20:03 |
nmz787 | yashagaroth: how do you expect electroporating muscle without uneven transfection? | 20:03 |
yashgaroth | did you see my most recent reply? | 20:03 |
nmz787 | yashagaroth: I've seen some microneedle matrices lately, but they were for allergy tests | 20:03 |
nmz787 | yashagaroth: i did, but didn't think it mentioned uneven expression | 20:04 |
nmz787 | are you saying the plasmid/protein would diffuse between cells? | 20:04 |
zacharycohn | i've heard seattle has a good biotech scene | 20:04 |
yashgaroth | sure it did, the plasmid spreads along the entire fiber, and the follistatin's effect extends to nearby fibers, not just the transfected ones | 20:04 |
zacharycohn | i don't know anything about it though | 20:04 |
nmz787 | but how many fibers are there in a square centimeter of meat? | 20:05 |
yashgaroth | zach: it does, but apparently it's very insular, and still tiny compared to SD/bay area/cambridge | 20:05 |
zacharycohn | ah | 20:05 |
yashgaroth | I've no idea how many fibers there are, lemme find the mean diameter | 20:05 |
zacharycohn | nmz787: I just bought 4lbs of steak. I'll go find out for you. | 20:06 |
nmz787 | is a muscle fiber a single cell (multinucleated as it may be) | 20:06 |
zacharycohn | kanzure: You going to SXSW (or more specifically, any of the SXSW parties?) | 20:06 |
yashgaroth | so like 50-100 micrometers | 20:07 |
yashgaroth | it's sort of a single cell, depending on how you define a cell | 20:07 |
nmz787 | hmm, ok so plausibly one cell | 20:07 |
nmz787 | one outer membrane | 20:07 |
yashgaroth | then yes, they're single cells | 20:07 |
nmz787 | but i doubt the plasmid would diffuse between fibers | 20:07 |
yashgaroth | no, but the protein would | 20:07 |
nmz787 | how would it get shuttled between? e.coli don't share beta-lactamase | 20:08 |
yashgaroth | beta-lactamase acts intracellularly anyway, this is a secreted product | 20:08 |
yashgaroth | the myostatin target is also extracellular | 20:09 |
yashgaroth | also why would e.coli want to share antibiotic resistance, they're selfish bastards | 20:10 |
kanzure | zacharycohn: i might be in SF actually | 20:11 |
kanzure | zacharycohn: i don't know yet | 20:11 |
kanzure | i might crash a party or two | 20:11 |
zacharycohn | Ah. Well if you're in Austin, let me know. the whole Startup Weekend crew is coming down | 20:11 |
zacharycohn | next wed-mon, I think | 20:12 |
kanzure | i live in austin | 20:12 |
kanzure | i have a room available actually | 20:12 |
kanzure | having a room during sxsw this makes me king of the world basically | 20:13 |
nmz787 | yashagaroth: so the myostatin binds extracellularly? | 20:14 |
kanzure | myostatin is a negative regulator of muscle mass | 20:14 |
yashgaroth | it acts on cell-surface receptors, yes | 20:14 |
kanzure | so if you bind and neutralize myostatin then you decrease its effect of prohibiting muscle growth | 20:14 |
yashgaroth | ^ | 20:14 |
kanzure | s/prohibiting/limiting | 20:15 |
kanzure | whatever | 20:15 |
kanzure | Just lots of down and up arrows | 20:15 |
yashgaroth | \/ | 20:15 |
kanzure | http://diyhpl.us/~bryan/papers2/myostatin/ | 20:15 |
nmz787 | wikipedia says whippets are a 'null' | 20:15 |
nmz787 | any idea what that means? | 20:15 |
nmz787 | its just NO2 | 20:15 |
kanzure | http://diyhpl.us/~bryan/papers2/myostatin/myostatin_inhibition.txt | 20:15 |
yashgaroth | yes, they lack a functional gene for myostatin | 20:16 |
yashgaroth | same with belgian blue cattle, as well as a few other breeds | 20:16 |
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yashgaroth | if you knock out the gene, or otherwise mutate it into non-functionality, you get the double muscling | 20:16 |
nmz787 | wait, whippets are different than inhaled 'whip-its' | 20:17 |
nmz787 | ? | 20:17 |
yashgaroth | heh | 20:17 |
nmz787 | e.g. nitrous oxide | 20:17 |
nmz787 | lol | 20:17 |
nmz787 | derr | 20:17 |
nmz787 | :P | 20:17 |
zacharycohn | kanzure: airbnb that shit! | 20:18 |
zacharycohn | you could make a killing | 20:18 |
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kanzure | hi splicer. | 20:34 |
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delinquentme | you guys have any idea if I need to restart my EC2 servers for the security group changes to take effect? | 20:58 |
kanzure | o.o i forget sorry man | 21:03 |
kanzure | all i know is that s3 security has always been a pain in the butt for me | 21:03 |
delinquentme | oh damn! | 21:20 |
delinquentme | i failed to show it off in here | 21:21 |
delinquentme | turns out no restarts are required when you edit a security group that a particular instance belongs to | 21:21 |
joshcryer | What are you guys using it for? | 21:23 |
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joshcryer | Paul Gilding = full of shit snoozefest | 22:03 |
joshcryer | I hope Diamandis is at least moderately more interesting in making his case. | 22:04 |
joshcryer | strangewarp, heh, I just started Diamandis' talk and he said exactly what I said in the first few mins, weird! | 22:07 |
joshcryer | (I had not seen it when I made that statement) | 22:07 |
kanzure | bleh | 22:07 |
kanzure | implementing interval arithmetic | 22:07 |
kanzure | why doesn't sympy do this already | 22:07 |
kanzure | all i want is to substitute x with [1,5] | 22:07 |
yashgaroth | diamandis said that gilding is full of shit? | 22:07 |
yashgaroth | or you just mean his talk took the opposite position | 22:08 |
joshcryer | No, no, yesterday I said: | 22:11 |
joshcryer | 04:42 < joshcryer> It's contrasted with a distopian future. | 22:11 |
joshcryer | 04:42 < joshcryer> People are pessimists, the negativity fed to them on a regular basis. | 22:11 |
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joshcryer | And Diamandis started his talk with that. | 22:11 |
Juul | ach, dna annotation scripts are tedious business | 22:11 |
yashgaroth | ahh okay | 22:12 |
joshcryer | Diamandis was far more convincing. | 22:22 |
joshcryer | I mean, truly night and day. | 22:22 |
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Stee| | hey | 22:39 |
yashgaroth | whatup | 22:39 |
Stee| | I actually consulted for diamandis new book | 22:41 |
joshcryer | Stee|m very cool. :) | 22:41 |
joshcryer | s/m/, | 22:41 |
-!- Stee| is now known as Steel_ | 22:41 | |
Steel_ | hm | 22:42 |
joshcryer | Hmm, "Abundance: The Future Is Better Than You Think" | 22:45 |
Steel_ | yeah | 22:45 |
joshcryer | Does the book devel much into the 3D printing aspect? | 22:45 |
Steel_ | rather, I 'am' consulting on the continuation of the work that went into the book, not what's currently in it | 22:46 |
Steel_ | my work more involves empirical ways to track increased energy/food/water/freedom/education/shelter, etc. | 22:46 |
Steel_ | I'm assigned to energy | 22:46 |
yashgaroth | hey bro have you heard about thorium? ron paul | 22:46 |
joshcryer | lol thorium | 22:47 |
Steel_ | I like thorium but not ron paul | 22:47 |
Steel_ | :( | 22:47 |
yashgaroth | haha me too | 22:48 |
joshcryer | Steel_, what say you about that MIT professors projection that solar will be $0.05 per kwh in 8 years? | 22:48 |
Steel_ | I haven't researched enough into future solar. I think that the price won't go down as much, much more likely you'll see reduced subsidies | 22:49 |
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Steel_ | I swear to god one of the people on my forum is my great aunt, but I can't say for sure | 23:54 |
joshcryer | lol | 23:55 |
joshcryer | What kind of forum would you have to attract a great aunt? | 23:55 |
Steel_ | I have a transhumanism forum that I'm trying to get going, and my great aunt is a neuropsychiatrist | 23:57 |
--- Log closed Fri Mar 02 00:00:33 2012 |
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