--- Log opened Mon Jun 11 00:00:37 2012 | ||
sylph_mako | Does anyone remember the name of that city which didn't appear to be built for humans? | 00:10 |
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Utopiah | Brasilia? | 00:10 |
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strangewarp | The Chaco Canyon pueblo complexes? Although it was probably a forced-tribute architectural project extorted out of slaves.. | 00:12 |
sylph_mako | -_- no. Like. Ancient ruins; unnavigable without climbing gear, apparently by design. Might be a crock but I have a WHACKY THEORY I want to investigate if it's not. | 00:12 |
strangewarp | Oh, not Chaco Canyon then | 00:12 |
sylph_mako | That was in reply to an earlier comment. | 00:13 |
* strangewarp nods | 00:13 | |
strangewarp | Chaco Canyon is mostly flat though, which is why I say it can't be that :p | 00:14 |
Utopiah | Machu Picchu? | 00:26 |
sylph_mako | seems unlikely. | 00:35 |
sylph_mako | At least most of it is hospitable. | 00:36 |
strangewarp | If it's Mesa Verde, they already probably figured it out - it was built as a last line of defense against a rampaging band of Aztecs, probably by the descendents of the people who were probably enslaved to build the Chaco Canyon pueblo complexes | 00:37 |
* strangewarp lots of "probably" caveats, since there is still some controversy I think | 00:39 | |
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delinquentme | anyone happen to have the research paper on whatever process was used to get insulin from microbes? | 11:26 |
delinquentme | was this written about in a research paper? | 11:26 |
chris_99 | are you thinking of that video a while back | 11:30 |
chris_99 | because what he did wasn't actually creating insulin | 11:30 |
chris_99 | it was an 'art' project apparently | 11:30 |
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delinquentme | chris_99, I can think of one video which was on jalopnik or something that was makin prozack or something | 12:03 |
delinquentme | Is there some hello world for novel compound creation in yeast? | 12:03 |
chris_99 | oh yeah it was prozac | 12:04 |
chris_99 | i'd be interested in that too delinquentme | 12:04 |
chris_99 | just bought a book about yeast | 12:04 |
delinquentme | chris_99, I've got some in my freezer :D | 12:04 |
chris_99 | for what? | 12:05 |
delinquentme | and a bunch of 96 well microplates | 12:05 |
chris_99 | ooh cool | 12:05 |
delinquentme | baking I think lol | 12:05 |
chris_99 | nice, i do brewing | 12:05 |
delinquentme | you know about the iGem group that put resveratrol into beer right? | 12:05 |
chris_99 | nope | 12:05 |
delinquentme | google that shit! | 12:05 |
delinquentme | i think it was last years iGem | 12:06 |
chris_99 | very interesting, so it extends the life of yeast? | 12:06 |
delinquentme | bewm! | 12:06 |
delinquentme | http://www.iptv.org/exploremore/ge/what/insulin.cfm | 12:06 |
chris_99 | cool | 12:07 |
@kanzure | update: walnut creek sucks | 12:25 |
jrayhawk | i bet it's not even made of walnuts :mad: | 12:25 |
@kanzure | in a walut up a creek without a paddle | 12:25 |
@kanzure | .. i a walutshell | 12:25 |
@kanzure | *in a walnutshell | 12:25 |
@kanzure | i kept trying to think of brilliant walnut/creek jokes, but i've got nothing yet | 12:26 |
@kanzure | but it's def. nice to see the FBI go all out on a 1-star hotel | 12:26 |
jrayhawk | the GSA took all the nice ones | 12:28 |
@kanzure | http://images.memegenerator.net/instances/21869192.jpg | 12:29 |
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@kanzure | lolz it's just raining money in SF isn't it? | 13:36 |
@kanzure | (nailed another contract; haven't been here for long) | 13:36 |
@kanzure | in other news: turtles fall out of love after 115 years http://news.discovery.com/animals/tortoise-couple-breaks-up-120611.html (yes i'm kidding, i don't expect any of you to click) | 13:47 |
_Sketch_ | kanzure: What do you do for work? | 14:23 |
@kanzure | sit around naked all day | 14:24 |
@kanzure | mostly software contracting- web apps, mobile apps, the works | 14:25 |
_Sketch_ | aha. | 14:26 |
_Sketch_ | Dangit. Is all mind-mapping software in Java? :( | 14:26 |
@kanzure | mind-mapping software tends to suck immensely | 14:27 |
_Sketch_ | WikkaWiki is PHP! yaaaaay | 14:27 |
_Sketch_ | So it would seem, kanzure. | 14:27 |
_Sketch_ | I could write my own... amazing, programming is like having superpowers. ;) | 14:28 |
_Sketch_ | But I'm pressed for time, so searching is way easier. Hee. | 14:29 |
@kanzure | i don't think php is the right solution for your problem | 14:37 |
@kanzure | but i you are married to php, i think semanticmediawiki has some silly mindmapping mod/plugin thing | 14:37 |
@kanzure | *if you are | 14:37 |
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_Sketch_ | 'yaaaay' being entirely sarcastic. | 14:44 |
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@kanzure | someone was asking for the current location of a library genesis.. | 14:50 |
@kanzure | http://libgen.info/ | 14:50 |
@kanzure | "Wow, I love my room btw. I've got a sliding glass door that leads out directly to the pool area. I'm thinking after-hours get togethers. :-)" | 15:06 |
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@kanzure | 1) is he coming on to me | 15:06 |
@kanzure | 2) why does he get the cool room >:( | 15:07 |
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chris_99 | do you use Flask kanzure? | 15:18 |
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@kanzure | chris_99: sometimes, but not on anything in production at the moment | 15:32 |
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chris_99 | aha cool, i've just started using it, i've had to give up on Play unfortunately do to memory issues | 15:32 |
@kanzure | Magic-Smoke: are you the magic smoke that keeps escaping my resistors? | 15:32 |
@kanzure | chris_99: give django a shot | 15:32 |
@kanzure | chris_99: and then repent and learn rails/sinatra anyway | 15:33 |
chris_99 | django/rails are too heavy weight for what i need | 15:33 |
@kanzure | have you used them before? | 15:33 |
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chris_99 | i've looked into them | 15:33 |
chris_99 | but not used them | 15:33 |
@kanzure | the biggest shock to me when i picked up rails was how many more gems and plugins there were than for django. | 15:37 |
@kanzure | flask is more similar to sinatra, of course | 15:37 |
chris_99 | because i've only got a limited amount of ram i want something that's as small as possible really | 15:39 |
@kanzure | jrayhawk: so, i made a merge commit in a feature branch a few weeks ago, committed a bunch of new stuff, and now want to rebase on master instead of merging things around | 15:42 |
@kanzure | jrayhawk: how do i correct this? i have to "undo" my merge from a thousand commits ago? | 15:42 |
@kanzure | or is the solution something else | 15:42 |
jrayhawk | well, the 'i don't have a particular reason to give a shit about the history' approach is to revert it | 15:57 |
jrayhawk | if this is an educational exercise or an excersize in pedanticism you can rebase or filter-branch depending on exactly what it is you want | 16:00 |
@kanzure | i'd like to keep the work i did, heh | 16:00 |
@kanzure | basically i want to pretend like i was rebasing on top o master the entire time, instead of that nasty merge commit in the iddle. | 16:01 |
jrayhawk | yeah, that's rebase's job | 16:01 |
@kanzure | someone else requested this; i convinced him that this isn't necessary.. but now i'm wondering how i would do it anyway. | 16:01 |
@kanzure | *on top of | 16:01 |
@kanzure | ok | 16:01 |
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delinquentme | I think the term " hit site " that I've been using is incorrect | 17:06 |
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delinquentme | anyways I'm looking for a program that I could compare a list of chemicals to a binding site for possible candidates | 17:07 |
@kanzure | CHARMM. | 17:07 |
@kanzure | or other molecular physics simulators. | 17:07 |
delinquentme | so like | 17:10 |
delinquentme | I need to do folding type processing to get out candidates? | 17:11 |
@kanzure | folding is only for folding amino acids into proteins | 17:12 |
delinquentme | biobricks dont happen to have their yield molecules in that database do they? | 17:14 |
delinquentme | bc I'd need those to run the site matching | 17:14 |
@kanzure | what? | 17:14 |
delinquentme | of the "hit sites" | 17:14 |
delinquentme | like where the molecules would bind to one another | 17:14 |
@kanzure | biobricks can't do "yields" because that entirely depends on the circuit, not the component | 17:15 |
@kanzure | the binding sites are annotated in pdb and on some ncbi somewhere, probably entrez | 17:15 |
@kanzure | *on some ncbi site somewhere | 17:15 |
delinquentme | so it would be more what that gene codes for | 17:15 |
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@kanzure | what are you doing? | 17:16 |
delinquentme | biobricks contains genes as well | 17:16 |
delinquentme | I'm trying to put together a simple example of picking out a molecule from the KEGG database | 17:16 |
delinquentme | and then matching it with some new gene to make a novel modification | 17:16 |
@kanzure | do you mean a protein? | 17:16 |
@kanzure | ok. so you want to find proteins that bind together? | 17:17 |
delinquentme | yeah | 17:17 |
@kanzure | look up cofactors or ligand binding | 17:17 |
delinquentme | what they make is totally arbitrary so long as whatever protein the new gene codes for is non-naturally occuring | 17:18 |
delinquentme | and it reacts with / matches the selected protein yield from the normal Ecoli pathway | 17:18 |
@kanzure | ok then that is called "rational protein design" or "rational protein engineering" | 17:18 |
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delinquentme | kk | 17:20 |
delinquentme | be back later | 17:20 |
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fenn | archels: http://nipo1987.web.fc2.com/RRK.html | 18:21 |
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-!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 256 seconds] | 22:46 | |
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--- Log closed Tue Jun 12 00:00:38 2012 |
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