--- Log opened Fri Aug 31 00:00:12 2012 | ||
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kanzure | "There was a security problem at Bio.CC. Kanzure put a soft link in the HTTPD dirctory to its mother directory which made private directories exposed to the world and some private files were up on Google site. It caused a rather serious problem." | 00:28 |
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kanzure | oh was that me | 00:28 |
kanzure | hm. i wish someone would have told me. | 00:28 |
brownies | kanzure: smooth. | 00:29 |
kanzure | brownies: http://biofoundation.net/ it's like a never ending maze | 00:30 |
kanzure | apparently that was 2009 | 00:30 |
brownies | kanzure: so many colors! | 00:30 |
kanzure | http://open-bio.org/ | 00:31 |
kanzure | actually these are the guys who sequenced the tiger genome | 00:31 |
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brownies | that's pretty impressive | 00:38 |
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kanzure | so there's a cvs repository for http://bioinformatics.org/pogo/ that i seem to have access to | 01:50 |
kanzure | it's a bunch of visual basic | 01:50 |
kanzure | not sure i want this? | 01:50 |
brownies | no one ever wanted visual basic | 01:50 |
brownies | also, isn't it 4am for you? | 01:50 |
kanzure | time has no meaning to me | 01:50 |
kanzure | wait, yes it does | 01:50 |
brownies | time is an illusion | 01:50 |
brownies | lunchtime, doubly so. | 01:50 |
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chris_99 | some interesting videos here http://www.jove.com | 04:14 |
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kanzure | chris_99: dnatube.com also used to be a thing | 04:23 |
chris_99 | cool | 04:29 |
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delinquentme | hardware anyone ? http://imgur.com/a/7BHQI | 05:07 |
delinquentme | i need this. | 05:07 |
delinquentme | internally threaded ... something of an anchor | 05:07 |
foucist | delinquentme: have you checked the local hardware store? :P | 05:10 |
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delinquentme | foucist: nah i havnt :D | 05:13 |
delinquentme | any idea what they're called? | 05:13 |
foucist | nope.. just take the pic along though.. | 05:14 |
foucist | sure they have anchor type stuff around | 05:14 |
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foucist | they might have attachments like that in the concrete section | 05:15 |
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chris_99 | http://citizensciencequarterly.com/2012/03/25/gogofuge-an-open-source-microcentrifuge/ | 05:54 |
delinquentme | im not really with the wood astetic | 05:55 |
delinquentme | aestetic | 05:55 |
chris_99 | yeah i know what you mean heh | 05:55 |
chris_99 | it's a lot safer than using it spinning with no case though | 05:56 |
delinquentme | true. | 05:56 |
chris_99 | anyone use PIC32's per chance? | 05:59 |
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pasky | is it dangerous to mix piracetamol and coffee? | 06:29 |
chris_99 | paracetamol? | 06:30 |
chris_99 | if so read this http://www.netdoctor.co.uk/aches-and-pains/medicines/panadol-extra.html | 06:31 |
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pasky | *piracetam, sorry :) | 06:36 |
pasky | i keep confusing these two | 06:36 |
chris_99 | ah, no idea then sorry | 06:37 |
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strangewarp | I've mixed aniracetam and coffee and I've been fine for 5 months | 07:18 |
strangewarp | anecdote, of course | 07:19 |
strangewarp | Switching to citicoline, alpha-GPC, and noopept in a couple days, and we'll see how they work with coffee | 07:19 |
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chris_99 | are they supposed to help you focus better | 07:22 |
strangewarp | Focus and mental capacity, yeah | 07:22 |
chris_99 | noticably? | 07:22 |
strangewarp | Weirdly, for me, they work as an antidepressant, better even than SSRIs | 07:22 |
strangewarp | Noticably, yeah.. though I'd say more noticably for citicoline than aniracetam (but that might just be an effect of taking the minimum 'racetam dosage) | 07:23 |
chris_99 | cool, apparently they're prescription only in europe | 07:24 |
strangewarp | Yeah, I'm pretty sure they're only perscribed for Alzheimer's patients there, because humans are stupid | 07:24 |
delinquentme | you're born you get to grade school you do some socializing perhaps begin to question why you're here you find your spot in the social pecking order you maybe go to college you make out w some kids, maybe even get laid you find yourself a nice individual you feel comfortable around it starts to get serious you start to get older maybe joke about putting on a few pounds! your group of friends dwindles in size as everyone g | 07:35 |
ThomasEgi | general question. wasn't here a bot around that can snatch papers and/or create papers from websites? | 07:42 |
chris_99 | yeah there was, i think it was broken though | 07:44 |
ThomasEgi | oh never mind. the pdf was accessible. just had to turn on js to see the menu | 07:44 |
delinquentme | I think it had a p name | 07:44 |
delinquentme | idk though | 07:44 |
delinquentme | oh that got cut off | 07:44 |
delinquentme | *coupled* jealousy, personal beliefs about your shortcomings and laziness stop you from growth you start joking about "getting old" and you're not even 70 "jokes" start to become reality you pay more attention to how you're not healing as quickly perhaps find god while pondering it slowly begin to feed more into fate and accepting whats coming. those coping mechanism then have solidified into reality you're getting on in | 07:44 |
chris_99 | paperbot, delinquentme i think | 07:45 |
ThomasEgi | just in case someone would be interested in the paper http://www.frontiersin.org/neuroengineering/10.3389/neuro.16.005.2009/full | 07:45 |
delinquentme | in another 8 years you can retire find a nice little spot / habit to settle down in find a nice habit to become accustomed to as you let it slowly approach. | 07:45 |
delinquentme | yeah paper bot | 07:45 |
delinquentme | religious people being me are recruiting the next generation | 07:46 |
chris_99 | ThomasEgi, have you played with PICS? | 07:47 |
ThomasEgi | chris_99, i have a pic18 here. but i never used it. just got so used to atmel products :) | 07:50 |
delinquentme | PICS? | 07:50 |
delinquentme | oh programmers? | 07:50 |
chris_99 | microcontrollers delinquentme | 07:51 |
delinquentme | ohhh | 07:51 |
chris_99 | ah, no worries ThomasEgi just a PIC32 is giving me hassle | 07:51 |
ThomasEgi | chris_99, i do have some experience with embedded systems and microcontrollers in general. if that could help you | 07:51 |
chris_99 | basically it has multiple programming lines | 07:51 |
chris_99 | and i've set the lines it's supposed to use | 07:51 |
chris_99 | but the silly thing isn't programming | 07:51 |
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strangewarp | raaage | 09:00 |
* strangewarp tries to write music software at a less glacial pace | 09:00 | |
chris_99 | heh, cool, whatcha making | 09:01 |
strangewarp | MIDI sequencer for polyrhythmic sequences, controllable by any Monome-compatible grid device, with a tracker-inspired editor | 09:02 |
strangewarp | very informationally dense, compared to the usual things; but a very specialized program. Probably won't have more than 5 users. But I'm making it more for myself than anyone | 09:03 |
strangewarp | I credit nootropics with clearing up my emotional baggage enough that I can make this sort of thing, natch | 09:05 |
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strangewarp | pff | 09:05 |
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nsh | did anyone go to austin community college? | 09:35 |
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chris_99 | anyone play with LASERZ? | 12:25 |
chris_99 | (specifically gas ones) | 12:26 |
ThomasEgi | music? in my cd drive, sure ;) | 12:26 |
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chris_99 | haha | 12:26 |
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chris_99 | done HV ThomasEgi? | 12:26 |
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ThomasEgi | high voltage? | 12:42 |
ThomasEgi | on lasers?... bad idea | 12:42 |
chris_99 | CO2 lasers need around 20KV | 12:42 |
ThomasEgi | ah. | 12:44 |
ThomasEgi | i thought of diod lasers | 12:44 |
ThomasEgi | i just got some junkfood so.. my brain is focused on food atm^ | 12:45 |
chris_99 | heh, bon apetit | 12:45 |
ThomasEgi | thx. | 12:46 |
ThomasEgi | i did some HV experiments in the past. but nothing too serious | 12:46 |
chris_99 | ive just found CRTs give the right kind of voltage | 12:47 |
chris_99 | so possibly hacking one of those | 12:47 |
ThomasEgi | cascode thingies.. yep. they do :) | 12:48 |
ThomasEgi | be careful. they can hurd badly | 12:48 |
chris_99 | yeah, probably burn i expect | 12:48 |
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nmz787 | $5 ARM eval board https://estore.ti.com/Stellaris-LaunchPad.aspx?sp_rid_pod4=OTQ5MjAyMzI4NgS2&sp_mid_pod4=39667887 | 14:11 |
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ThomasEgi | not bad that board. but for little more you can have a lot more :) | 14:36 |
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kanzure | ThomasEgi: show me? | 15:32 |
kanzure | i am a sucker for $3 programmers | 15:32 |
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ThomasEgi | for 25 you get a raspberry. | 15:33 |
chris_99 | that's rather overkill though ;) | 15:33 |
ThomasEgi | true. but still comparebly affordable | 15:34 |
ThomasEgi | the right boards for the right job i guess | 15:35 |
kanzure | i was hoping for something that was still a microcontroller | 15:37 |
kanzure | when i was a youngin', i saw outrageous prices for programmers (>$50).. so what does >$50 buy me now? | 15:37 |
ThomasEgi | you can get an atmega u2 series. with onboard usb controller. | 15:38 |
chris_99 | hmm, i just bought a PICKIT3 programmer for £30 | 15:38 |
ThomasEgi | you don't need any programmer for them. | 15:38 |
ThomasEgi | just a reset button and the usb-connections. | 15:38 |
ThomasEgi | and a clock crystal. but that should be pretty close to 3 bucks | 15:39 |
kanzure | har har http://www.ibiblio.org/harris/500milemail.html | 15:46 |
ThomasEgi | old story. but always good for a smile | 15:54 |
kanzure | yeah it's ibiblio.org.. no way it can be recent :p | 15:56 |
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skorket | evening all | 16:29 |
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chris_99 | you could use spectroscopy to tell if certain chemicals are the same right? | 16:50 |
jrayhawk | Not structurally, but compositionally at least. | 16:55 |
chris_99 | yeah | 16:57 |
chris_99 | i'm tempted by one of these http://www.ebay.co.uk/itm/Compact-Fiber-Coupled-CCD-Spectrometer-Kit-DIY-/221117621936?pt=LH_DefaultDomain_0&hash=item337ba326b0 | 16:58 |
chris_99 | right time for bed, night peeps | 17:02 |
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kanzure | yashgaroth: hi | 19:25 |
kanzure | the methods in molecular bio loot will be done soon | 19:25 |
yashgaroth | you'll be up to your ears in giant wombats in no time | 19:26 |
brownies | glowing giant wombats, or gtfo | 19:27 |
kanzure | brownies: glowing tits or gtfo | 19:27 |
* nsh blinks until the words make sense | 19:28 | |
brownies | o.O | 19:48 |
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kanzure | wizaqua: hi | 20:41 |
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wizaqua | jhi | 21:00 |
kanzure | so, i wonder how much it would cost to actually go around digging up graves | 21:29 |
kanzure | i'm curious about stealing dna from the dead | 21:29 |
kanzure | in terms of manual labor, i doubt it's more than $500/coffin? | 21:29 |
jrayhawk | if you're digging it up clandestinely and replacing the dirt clandestinely | 21:33 |
jrayhawk | much cheaper if you can use a backhoe | 21:34 |
jrayhawk | even cheaper still if you just use a big core sample drill | 21:34 |
kanzure | huh? how would a core sample drill be cheaper than a backhoe | 21:34 |
jrayhawk | you don't need a lot of tissue, so your core sample drill can be very skinny and possibly operated by hand | 21:34 |
kanzure | i suppose so.. snake down a fiber optic camera and a drill/snatcherthing | 21:35 |
kanzure | maxwell was burried at Parton Chuchyard, Dumfries and Galloway, Scotland | 21:36 |
kanzure | hrm all these gravefinding sites are awful. i need a graveyard api. | 21:37 |
foucist | just access the zombie net | 21:38 |
joshcryer | wtf dna from the dead? why? | 21:59 |
yashgaroth | lot easier to find interesting genomes if you don't require them to be from the living | 22:03 |
sylph_mako | Do DNA sequences compress easily, as data? | 22:04 |
yashgaroth | it's hard to directly compare, but you can swap a good 80% of the genome between people with no effect | 22:05 |
joshcryer | I dispute that. | 22:06 |
yashgaroth | k | 22:06 |
joshcryer | Spend $500 to dig up a grave or give some dude on the street $5 for a swab. | 22:06 |
joshcryer | Go around searching through garbage outside of a university for condoms. | 22:07 |
yashgaroth | those people don't sound very interesting | 22:08 |
* joshcryer shrugs | 22:08 | |
joshcryer | Guess I see quantity over quality... | 22:08 |
yashgaroth | we've got various 'thousand genomes' projects for quantity | 22:09 |
joshcryer | I mean for value / expense. Are we doing bios of the dead? | 22:11 |
joshcryer | Or is it "well let's just hit that random gravestone." | 22:11 |
yashgaroth | [21:37:03] .:kanzure:. maxwell was burried at Parton Chuchyard, Dumfries and Galloway, Scotland | 22:12 |
yashgaroth | seems to imply it's not a random selection | 22:12 |
yashgaroth | if the name doesn't ring a bell, I don't know what to tell you | 22:12 |
joshcryer | Would DNA still be viable 100 years on? | 22:13 |
yashgaroth | in the bone marrow and with next-gen sequencing, maybe yes | 22:13 |
joshcryer | Then I fully endorse this endeavour. | 22:14 |
kanzure | condoms at a university will just get you mostly students | 22:14 |
joshcryer | Who might turn out to be interesting... | 22:15 |
yashgaroth | scott, and other polar explorers, will be easily readable until we care to find them | 22:15 |
yashgaroth | dead polar explorers* | 22:15 |
kanzure | dna is viable for up to 100,000 years ish it seems | 22:15 |
kanzure | so yes dna from the last few thousand years in graveyards is extractable | 22:15 |
yashgaroth | I take it that denisovan genome story spurred your interest | 22:16 |
joshcryer | Einstein's brain? | 22:16 |
kanzure | yashgaroth: what? don't know what that is | 22:16 |
kanzure | no i've thought about graverobbing for a while now | 22:16 |
foucist | http://www.guardian.co.uk/science/2012/aug/30/scientists-genetic-makeup-denisovan-girl | 22:16 |
yashgaroth | some proto-human got genome-sequenced with surprisingly good...err yeah ^ | 22:16 |
foucist | dna from 50k years ago | 22:17 |
kanzure | the problem with paying people is that they would want actual money | 22:17 |
kanzure | "well, i have this interesting metabolism mutation where i can eat big macs all day without problems. gimme $50k base and $20k/embryo." | 22:17 |
foucist | kanzure: i would also be careful to make any assumptions about the person you extracted dna from.. i mean, sure let's say you find maxwell's grave, drill down and extract some flesh. how do you know if it's maxwell's dna? chances are it's not | 22:18 |
joshcryer | I think I'd be more willing to lie than to dig up graves. *shrug* "Hi, I need a swab to test for dieseases, here's $5, I'll tell you the result later." | 22:18 |
yashgaroth | who else's dna would it be? | 22:19 |
foucist | unless you actually bring the coffin up and have a domain expert examine the remains to verify that it is in fact him | 22:19 |
kanzure | domain expert? in identifying corpses? heh | 22:19 |
yashgaroth | "he's dead alright" | 22:19 |
kanzure | "oh yep, that's definitely hitler. no doubt about it." | 22:19 |
foucist | domain expert in maxwell i mean | 22:19 |
kanzure | (my plans for super hitler are proceeding exactly as i have foreseen) | 22:20 |
yashgaroth | if someone's crafty enough to get their grave internationally recognized as maxwell's, they also have an interesting genome I'd say | 22:20 |
kanzure | but realistically it's probably <1000 mutations of interest | 22:21 |
joshcryer | What makes you interesting? | 22:23 |
kanzure | nothing? | 22:23 |
kanzure | in many cases i bet there will be nothing interesting | 22:23 |
kanzure | i also bet that the proprietarialists (?) will want to protect their "family heritage" against these sorts of actions | 22:24 |
kanzure | e.g. they will probably want to flush down a bone-eating bacteria | 22:24 |
foucist | for maxwell probably <10 genes of interest | 22:24 |
kanzure | of course, that's sort of silly for them to do since anyone can just follow them and get some hair eventually. | 22:25 |
foucist | both epigenetics & nurture probably accounts for a fair amount | 22:25 |
kanzure | but, still. | 22:25 |
foucist | rather than the base genes | 22:25 |
kanzure | foucist: i was never arguing toherwise | 22:25 |
kanzure | *otherwise | 22:25 |
foucist | kanzure: i was responding more to yashgaroth | 22:25 |
kanzure | epigenetics is no excuse to not go graverobbing | 22:25 |
foucist | like you were | 22:25 |
yashgaroth | oh I'm not interesting either | 22:25 |
yashgaroth | wait that was josh | 22:25 |
kanzure | it needs a better word than graverobbing | 22:26 |
kanzure | graverobbing is so crude | 22:26 |
yashgaroth | soul harvesting? | 22:26 |
yashgaroth | oooh bone reaving | 22:26 |
foucist | lol | 22:26 |
kanzure | well i was going more for grave birthing | 22:27 |
yashgaroth | copy venter and call it the "global grave sampling expedition" | 22:28 |
joshcryer | yashgaroth, you / 'whoever we're finding interesting' :P | 22:28 |
joshcryer | heh boan reaving | 22:28 |
yashgaroth | oh you know, have an equation or two named after you, that sort of thing | 22:29 |
kanzure | 'grave sampling expedition' sounds good to me | 22:30 |
joshcryer | Fair enough. I like it. | 22:30 |
joshcryer | kanzure, gravology? | 22:30 |
joshcryer | tombology | 22:30 |
kanzure | "My study is of the gravest sort." | 22:30 |
yashgaroth | I mean a.) there probably won't be anything concrete we can glean, and b.) I'm a communist, but one maxwell genome is still worth a thousand random peoples' | 22:30 |
kanzure | i think "grave sampling expedition" is even tame enough for kickstarter | 22:31 |
joshcryer | yashgaroth, imho you will find more concrete stuff by grabbing a few million people and ... educating them properly, then grabbing their DNA. | 22:31 |
yashgaroth | sounds expensive | 22:31 |
kanzure | joshcryer: it's still costly to sequence everyone | 22:32 |
joshcryer | As Moglen says, the greatest injustice is that, "every human society since the beginning, whenever that was, has wasted almost all the brains it possessed." | 22:32 |
foucist | Tomb Raider | 22:32 |
kanzure | foucist: i fail | 22:32 |
foucist | there are always interesting bones in tombs | 22:32 |
kanzure | i don't know why tomb raider wasn't my first idea | 22:33 |
foucist | heh | 22:33 |
kanzure | so, i'm not sure i would be able to find people who are already skilled at graverobbing | 22:34 |
kanzure | but, it's pretty easy to practice | 22:34 |
joshcryer | Good luck. | 22:34 |
foucist | "Fund a real life tomb raiding expedition!" | 22:34 |
kanzure | rewards? | 22:35 |
kanzure | hitler's fibula | 22:35 |
kanzure | oh he was cremated | 22:35 |
kanzure | that's a much harder problem | 22:35 |
joshcryer | Probably not a terribly interesting genome anyway. | 22:36 |
yashgaroth | cremated is a nice way to describe it in that particular case | 22:36 |
kanzure | i think this would just degenerate into a "congratulations! your kid gets to have a terrible life-threatening muscle dystrophy disease!" | 22:40 |
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foucist | kanzure: i'm sure many cemetaries have skilled grave diggers on staff | 22:41 |
foucist | probably could look for professional exhumers | 22:41 |
kanzure | they wouldn't want to participate because it's illegal (i'm pretty sure) | 22:41 |
ParahSailin_ | wait why do you guys wanna dig up bodies | 22:43 |
joshcryer | I had the same question, apparently to find interesting DNA from notable individuals. | 22:43 |
joshcryer | (also, I'm pretty sure kanzure is crazy, just a tiny bit) | 22:44 |
kanzure | bah you're just unwilling to do what's necessary | 22:44 |
joshcryer | It's the good kind of crazy. | 22:45 |
joshcryer | I fully endorse grave robbing notable individual DNA and reanimating them (including later on the possibility of a whole life simulation so that they are reasonable approximations of their pre-dead selves). | 22:48 |
joshcryer | The whole genome search for interesting mutations is thing is just a side effect. ;P | 22:49 |
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