| --- Log opened Fri Nov 23 00:00:25 2012 | ||
| -!- antis [~IceChat77@c-75-66-82-84.hsd1.tn.comcast.net] has left ##hplusroadmap [] | 00:11 | |
| -!- antis [~IceChat77@c-75-66-82-84.hsd1.tn.comcast.net] has joined ##hplusroadmap | 00:11 | |
| -!- Mariu [Jimmy98@89.41.57.33] has quit [Ping timeout: 244 seconds] | 00:31 | |
| -!- Mariu [Jimmy98@89.41.57.33] has joined ##hplusroadmap | 00:40 | |
| -!- Juul [~Juul@50-0-138-112.dsl.dynamic.sonic.net] has joined ##hplusroadmap | 00:46 | |
| -!- Juul [~Juul@50-0-138-112.dsl.dynamic.sonic.net] has quit [Ping timeout: 246 seconds] | 01:08 | |
| kanzure | beep | 01:32 |
|---|---|---|
| kanzure | internet archive live stream http://crawl432.us.archive.org/crawling/domain/liveupdates.html | 01:40 |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Ping timeout: 244 seconds] | 01:58 | |
| -!- Shehrazad [~Shehrazad@78.162.46.155] has joined ##hplusroadmap | 02:08 | |
| -!- Shehrazad [~Shehrazad@78.162.46.155] has quit [Changing host] | 02:08 | |
| -!- Shehrazad [~Shehrazad@unaffiliated/shehrazad] has joined ##hplusroadmap | 02:08 | |
| -!- Simurg [~Shehrazad@unaffiliated/shehrazad] has quit [Ping timeout: 244 seconds] | 02:09 | |
| -!- sylph_mako [~mako@103-9-42-1.flip.co.nz] has quit [Ping timeout: 252 seconds] | 02:27 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 02:35 | |
| -!- Guest95905 is now known as Coornail | 02:37 | |
| -!- ThomasEgi [~thomas@gw-ko-kostr2.inka-online.net] has joined ##hplusroadmap | 03:20 | |
| -!- ThomasEgi [~thomas@gw-ko-kostr2.inka-online.net] has quit [Changing host] | 03:20 | |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap | 03:20 | |
| -!- nmz787__ [~nmz787@131.252.130.248] has quit [Quit: leaving] | 03:22 | |
| -!- nmz787 [~nmz787@131.252.130.248] has joined ##hplusroadmap | 03:23 | |
| -!- nmz787 [~nmz787@131.252.130.248] has quit [Client Quit] | 03:24 | |
| -!- nmz787 [~nmz787@131.252.130.248] has joined ##hplusroadmap | 03:24 | |
| -!- Shehrazad [~Shehrazad@unaffiliated/shehrazad] has quit [Ping timeout: 246 seconds] | 03:45 | |
| -!- Shehrazad [~Shehrazad@95.5.78.210] has joined ##hplusroadmap | 03:58 | |
| -!- Shehrazad [~Shehrazad@95.5.78.210] has quit [Changing host] | 03:58 | |
| -!- Shehrazad [~Shehrazad@unaffiliated/shehrazad] has joined ##hplusroadmap | 03:58 | |
| -!- bjonnh [~Bjonnh@unaffiliated/bjonnh] has quit [Read error: Connection reset by peer] | 04:57 | |
| -!- _sol_ [~Sol@c-174-57-58-11.hsd1.pa.comcast.net] has quit [] | 05:24 | |
| kanzure | "当你把上面的条件逐一验证完之后，就会发现，关键词的科学设计，找优质客户就是那么简单" | 06:08 |
| kanzure | spam is so weird | 06:08 |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 244 seconds] | 06:30 | |
| juri_ | people are weirder. and thats *before* we start hacking them. | 06:32 |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 06:39 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 06:50 | |
| kanzure | juri_: what? | 06:52 |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 240 seconds] | 06:52 | |
| juri_ | what did i say that was unclear? | 06:58 |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Quit: Leaving] | 07:22 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 07:28 | |
| -!- ParahSailin [~parah@unaffiliated/parahsailin] has quit [Ping timeout: 248 seconds] | 07:46 | |
| -!- ParahSailin [~parah@unaffiliated/parahsailin] has joined ##hplusroadmap | 07:47 | |
| -!- EnLilaSko [~Nattzor@unaffiliated/enlilasko] has joined ##hplusroadmap | 07:54 | |
| -!- eudoxia [~eudoxia@r190-135-41-189.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap | 08:15 | |
| eudoxia | i think he's saying people will get wierder when they start going full transhuman | 08:16 |
| antifas | theres no reson not to go full transhuman | 08:17 |
| antifas | ppl arnt going to get any better | 08:17 |
| antifas | thats for sure | 08:17 |
| -!- abetusk_ [~abetusk@cpe-24-58-232-122.twcny.res.rr.com] has quit [Quit: Leaving] | 08:22 | |
| eudoxia | but i thought the whole point was to get better | 08:23 |
| antifas | not getting better without science | 08:24 |
| eudoxia | of course | 08:28 |
| kanzure | okay? | 08:30 |
| kanzure | i still don't get it. i was complaining about spam, and for some reason this leads to epic philosophical crap? | 08:30 |
| antifas | nothing epic or philosophical, just the facts maam | 08:31 |
| -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 255 seconds] | 08:37 | |
| -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap | 08:49 | |
| -!- eudoxia [~eudoxia@r190-135-41-189.dialup.adsl.anteldata.net.uy] has quit [Quit: quit] | 08:50 | |
| -!- Mokstar [~Nate@c-76-115-140-241.hsd1.or.comcast.net] has quit [Read error: Connection reset by peer] | 08:56 | |
| -!- Mokstar [~Nate@c-76-115-140-241.hsd1.or.comcast.net] has joined ##hplusroadmap | 08:57 | |
| -!- antifas [~safitan@75.105.12.23] has quit [Read error: Connection reset by peer] | 09:09 | |
| -!- antifas [~safitan@75.105.12.23] has joined ##hplusroadmap | 09:24 | |
| kanzure | hah since when does andrew have a site http://andrewhessel.com/ | 09:26 |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has joined ##hplusroadmap | 09:28 | |
| -!- ParahSail1in [~eg@unaffiliated/parahsailin] has quit [Ping timeout: 245 seconds] | 10:01 | |
| -!- sylph_mako [~mako@103-9-42-1.flip.co.nz] has joined ##hplusroadmap | 10:17 | |
| -!- yashgaroth [~f@cpe-66-27-117-179.san.res.rr.com] has joined ##hplusroadmap | 10:23 | |
| kanzure | yashgaroth: hi | 10:23 |
| yashgaroth | yo | 10:23 |
| -!- mgodinho [~user@pdpc/supporter/active/mgodinho] has joined ##hplusroadmap | 10:41 | |
| -!- mgodinho [~user@pdpc/supporter/active/mgodinho] has quit [Client Quit] | 10:41 | |
| -!- mgodinho [~user@pdpc/supporter/active/mgodinho] has joined ##hplusroadmap | 10:42 | |
| -!- antifas is now known as |antifas| | 10:52 | |
| -!- jordyd [~jordyd@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has joined ##hplusroadmap | 11:41 | |
| -!- jordyd [~jordyd@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has quit [Changing host] | 11:41 | |
| -!- jordyd [~jordyd@unaffiliated/jordyd] has joined ##hplusroadmap | 11:41 | |
| -!- jordyd [~jordyd@unaffiliated/jordyd] has quit [Quit: Leaving] | 11:48 | |
| -!- synacktic_ [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has joined ##hplusroadmap | 11:48 | |
| -!- synacktic_ [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has quit [Read error: Connection reset by peer] | 11:49 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has joined ##hplusroadmap | 11:49 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has quit [Changing host] | 11:49 | |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has joined ##hplusroadmap | 11:49 | |
| -!- mgodinho [~user@pdpc/supporter/active/mgodinho] has quit [Ping timeout: 244 seconds] | 12:10 | |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has quit [Read error: Connection reset by peer] | 12:42 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has joined ##hplusroadmap | 12:42 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has quit [Changing host] | 12:42 | |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has joined ##hplusroadmap | 12:42 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 13:25 | |
| archels | kanzure: what websites is Eugen talking about? | 13:45 |
| kanzure | postbiota.org | 13:45 |
| kanzure | really it's just a mailing ilst | 13:45 |
| kanzure | i'm not sure why that would be any trouble to host | 13:45 |
| archels | ~4000 euros in bandwidth? | 13:54 |
| kanzure | wtf | 13:55 |
| kanzure | "Still, when faced up to 4 kEUR/month additional costs overnight" | 13:55 |
| kanzure | oh ok, so that's just +4000 not his usual payment | 13:55 |
| jrayhawk | oh, it's a separate domain | 13:57 |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has quit [Ping timeout: 246 seconds] | 14:04 | |
| -!- Mariu [Jimmy98@89.41.57.33] has quit [Quit: leaving] | 14:05 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has joined ##hplusroadmap | 14:17 | |
| -!- synacktic [~synacktic@99-177-65-98.lightspeed.wepbfl.sbcglobal.net] has quit [Changing host] | 14:17 | |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has joined ##hplusroadmap | 14:17 | |
| -!- synacktic [~synacktic@unaffiliated/jordyd] has quit [Remote host closed the connection] | 14:18 | |
| -!- srangewarp [~strangewa@c-67-173-247-251.hsd1.co.comcast.net] has joined ##hplusroadmap | 14:21 | |
| -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 240 seconds] | 14:22 | |
| -!- strangewarp [~strangewa@c-67-173-247-251.hsd1.co.comcast.net] has joined ##hplusroadmap | 14:23 | |
| -!- srangewarp [~strangewa@c-67-173-247-251.hsd1.co.comcast.net] has quit [Ping timeout: 260 seconds] | 14:26 | |
| -!- cakeboss [~r00t@c-68-52-67-194.hsd1.tn.comcast.net] has joined ##hplusroadmap | 14:39 | |
| kanzure | cakeboss: hi | 14:41 |
| cakeboss | kanzure: h | 14:46 |
| -!- _Sol_ [~Sol@c-174-57-58-11.hsd1.pa.comcast.net] has joined ##hplusroadmap | 14:51 | |
| -!- payclonej [~irchon@75.105.12.23] has joined ##hplusroadmap | 14:51 | |
| kanzure | cakeboss: what brings you here? | 14:52 |
| -!- payclonej [~irchon@75.105.12.23] has quit [Client Quit] | 14:54 | |
| cakeboss | kanzure: I am a hacker of sorts. Interested in biology, worked in a genetics lab. Thought this would be a fun hobby. | 14:57 |
| cakeboss | I am minoring in biology. | 14:58 |
| kanzure | http://mike-ibioloid.blogspot.com/2012/11/why-3dsystems-lawsuit-against-formlabs.html | 15:15 |
| kanzure | "Why 3dsystems lawsuit against Formlabs for patent infringement has no merit" | 15:15 |
| kanzure | oh the lawsuit is against kickstarter itself? | 15:16 |
| -!- EnLilaSko [~Nattzor@unaffiliated/enlilasko] has quit [Quit: - nbs-irc 2.39 - www.nbs-irc.net -] | 15:51 | |
| -!- lichen [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has quit [Quit: Lost terminal] | 15:56 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] | 16:08 | |
| cakeboss | kanzure: Is there a website? | 16:47 |
| kanzure | for kickstarter? | 16:48 |
| cakeboss | kanzure: for hplusroadmap or diybio. An active group that participates in research, anything. | 16:48 |
| kanzure | http://diyhpl.us/wiki/diybio/faq | 16:49 |
| kanzure | http://diyhpl.us/wiki/diybio/groups | 16:49 |
| cakeboss | kanzure: thanks | 16:49 |
| cakeboss | Hm. There aren't any for my region, is there information on starting a group in the faq? | 16:50 |
| kanzure | probably, but i forget where | 16:50 |
| kanzure | basically just hang out with interesting people | 16:50 |
| kanzure | where are you? | 16:51 |
| cakeboss | Do any of them conduct legitimate research? | 16:51 |
| kanzure | what do you consider legitimate | 16:51 |
| cakeboss | I am in the deep south of the UA | 16:51 |
| kanzure | united arab emirates? | 16:51 |
| cakeboss | kanzure: scientific journals | 16:51 |
| cakeboss | kanzure: sorry, multitasking. I am in the US. | 16:51 |
| kanzure | some of the diygenomics people published some crap in a journal, if that matters | 16:52 |
| kanzure | well, where in the US? | 16:52 |
| cakeboss | Alabama. | 16:52 |
| kanzure | you should talk with heath matlock (ybit) | 16:52 |
| cakeboss | Ah. | 16:52 |
| kanzure | he's our guy in alabama for this | 16:52 |
| cakeboss | Is he a student or a professor? | 16:53 |
| kanzure | neither | 16:53 |
| cakeboss | Ah | 16:53 |
| cakeboss | Hence the diybio part, I forget. heh. | 16:53 |
| cakeboss | Well great. I will stick around to get into contact with him then. | 16:54 |
| kanzure | eh just pester him at heathmatlock@gmail.com | 16:54 |
| cakeboss | Thanks. | 16:54 |
| -!- cpopell [ad4908a0@gateway/web/freenode/ip.173.73.8.160] has joined ##hplusroadmap | 16:56 | |
| -!- cpopell [ad4908a0@gateway/web/freenode/ip.173.73.8.160] has quit [Client Quit] | 16:57 | |
| juri_ | are there any people for this in the DC area? | 17:03 |
| cakeboss | I am sure there are, kanzure? | 17:03 |
| kanzure | there's the baltimore stuff | 17:06 |
| kanzure | http://www.bugssonline.org/ | 17:07 |
| kanzure | http://www.genoblasts.com/ | 17:07 |
| juri_ | I have a LOT of reading to do, in order to accomplish what i want to do. its all impossible, at the moment.. but that doesn't mean i can't make it slightly-less-impossible. | 17:09 |
| juri_ | I'm thinking that first, we should build a 3d printer with a self leveling bed. | 17:14 |
| juri_ | then learn to move the extruder around (and hense the nozzle) at increasingly high precisions, using cdrom drive laser/optic mechanisms to determine position of extruder relative to x carriage... | 17:17 |
| juri_ | so, step 1 is new X carriage, that allows for a trinary optics system, so we can range-find the bed. | 17:19 |
| juri_ | I should be able to handle the image recognition output from three laptop-web-cams, to pull that off. | 17:20 |
| juri_ | oh, wait, i'm in the wrong channel. sorry about that. ;) | 17:21 |
| cakeboss | juri_: what are you wanting to do exactly? | 17:22 |
| juri_ | cakeboss: i've got a friend who wants to design high quality neural probes. instead of using live animal testing, i'm trying to get good enough at building small structures to send him repeatedly back to the drawing board. | 17:23 |
| cakeboss | juri_: ah | 17:23 |
| juri_ | basically, he can build, then i can build, then we test, and i send him back to the board. | 17:23 |
| juri_ | so, i need to build animals, specializing on neural tissue to pull that off. | 17:24 |
| juri_ | i figure the first thing to do is build the algae pick-and-place machine that's at http://diybio.org/2012/06/12/gaudilabalgaepicker/ , only on top of a prusa mendel 3d printer style. | 17:25 |
| juri_ | something between the two, with much better documentation. | 17:25 |
| juri_ | this way i can pick-and-place cells, while i learn about methods of generating appropriate extracelular matricies. | 17:26 |
| juri_ | it also gets me to the point of 'contributing back' very quickly, as the documentation on that picker is lacking, to say the least. | 17:27 |
| cakeboss | juri_: I actually used to do my own research in something similiar | 17:29 |
| cakeboss | juri_: specifically with p21 and neural regeneration | 17:29 |
| juri_ | Interesting. | 17:32 |
| cakeboss | si | 17:32 |
| juri_ | I'm not so interested in changing cell behavior. more in just printing out the stuff we already have. | 17:33 |
| kanzure | juri_: if you modify cell behavior, that becomes easier. | 17:33 |
| * juri_ nods. | 17:33 | |
| juri_ | I can tell. | 17:33 |
| juri_ | still, the 'great unsolved' is still printing an ECM, and transporting live sells into the ECM. | 17:34 |
| kanzure | by the way, you're evil for perpetuating inconsistent personal pronoun capitalization | 17:34 |
| juri_ | hah. ;) | 17:35 |
| juri_ | I try to remember. I just fail. ;) | 17:35 |
| kanzure | printing cells isn't unsolved, you should read jmil's work | 17:36 |
| kanzure | it seems jmil isn't logged in | 17:36 |
| juri_ | i don't figure its unsolved, just poorly documented. afte all, i've seen the TED talk. ;) | 17:36 |
| juri_ | just trying to reproduce work, and build better printers. | 17:37 |
| kanzure | TED is not a useful medium for science | 17:37 |
| cakeboss | ^ | 17:37 |
| cakeboss | For the record, cakeboss' cakes are just awful. | 17:38 |
| juri_ | my 3d printers look pretty terrible. i build out of mostly scrap. ;) | 17:41 |
| kanzure | why are you always winking, shit | 17:41 |
| * juri_ shrugs. | 17:41 | |
| juri_ | i've always been emoticon-heavy. | 17:41 |
| cakeboss | protip: juri_ is flirting with kanzure | 17:42 |
| kanzure | fuck | 17:42 |
| AdrianG | TED is worthless and must be destroyed | 17:44 |
| cakeboss | AdrianG: TED is so meaningful and really gives us lamers the most simplicitive explanations of what we just can't understand without them. | 17:44 |
| AdrianG | orly | 17:44 |
| cakeboss | no, not rly | 17:45 |
| AdrianG | for a second I was woried you may be suffering from an occult mental illness | 17:45 |
| cakeboss | Aside from my obsession of TED, none whatsoever | 17:45 |
| cakeboss | with* | 17:46 |
| juri_ | I enjoy ted talks. | 17:47 |
| juri_ | they make good background, while doing useful stuff. | 17:47 |
| cakeboss | juri_: useful stuff like reading about TED? | 17:47 |
| juri_ | no, like writing patches to softwares. ;) | 17:48 |
| -!- mode/##hplusroadmap [+o kanzure] by ChanServ | 17:48 | |
| cakeboss | juri_: what languages do you know? | 17:48 |
| juri_ | cake: primarily, i write in shell/XSLT/C. | 17:49 |
| -!- juri_ was kicked from ##hplusroadmap by kanzure [;)] | 17:49 | |
| -!- juri_ [juri@funkykitty.net] has joined ##hplusroadmap | 17:49 | |
| cakeboss | nice | 17:49 |
| juri_ | for a full list, i'd scroll the channel into oblivion. ;) | 17:50 |
| cakeboss | I am currently writing software that will automate catching intruders in a network by various means, including watermarking data streams | 17:50 |
| @kanzure | cakeboss: what a coincidence, i find new ways to obfuscate my footprint | 17:50 |
| @kanzure | and ripping out watermarks from pdfs | 17:50 |
| cakeboss | kanzure: aha. Also I am building software that will track hackers by nothing more than their handle. I have around a 90%+ success rate. | 17:51 |
| @kanzure | huh? | 17:52 |
| cakeboss | For instance, I take your name 'kanzure'. I can use that to find out your full name where you live. | 17:52 |
| @kanzure | welcome to whois | 17:52 |
| juri_ | ah. another person who uses 'hacker' to mean 'network intruider'. | 17:52 |
| @kanzure | are you an idiot, or are you trolling me | 17:52 |
| * juri_ throws rocks at cakeboss. | 17:52 | |
| cakeboss | juri_: nope.avi | 17:52 |
| cakeboss | hacker != network intruder | 17:53 |
| cakeboss | read above | 17:53 |
| cakeboss | kanzure: I am not talking about with just your /whois.... | 17:54 |
| @kanzure | you'd have to be an idiot to not be able to get my address from the web | 17:54 |
| @kanzure | i paste it all over the fucking place | 17:54 |
| @kanzure | what do you mean 90% success rate.. it should be 100% success rate. | 17:54 |
| cakeboss | kanzure: You aren't a hacker, this is designed for people who aren't spreading their information across the web... | 17:54 |
| @kanzure | hear that everyone, i'm officially not a hacker | 17:55 |
| @kanzure | YOu HEARD IT HERE FIRST | 17:55 |
| juri_ | you'd have to be pretty smart to get my address (i do not know what it is), but information about me is everywhere. | 17:55 |
| cakeboss | meh, w.e | 17:55 |
| @kanzure | NO TAKESIES-BACKSIES | 17:55 |
| juri_ | kanzure: congratulations! | 17:55 |
| @kanzure | what? | 17:56 |
| cakeboss | kanzure: from what I know about you, you aren't a hacker. You are just someone in an IRC channel. This software has been used on people like Sabu, for instance. | 17:56 |
| juri_ | ah. so again, someone who intrudes on networks. | 17:56 |
| @kanzure | cakeboss: i know you mean well | 17:56 |
| cakeboss | juri_: That is not the only thing he ever did. | 17:56 |
| * juri_ continues pelting cakeboss with bigger rocks. | 17:56 | |
| @kanzure | juri_: i think english isn't your native language | 17:56 |
| juri_ | kanzure: astute. | 17:57 |
| juri_ | its close to my native language, does that count? | 17:57 |
| @kanzure | no | 17:57 |
| cakeboss | juri_: Tu hablo espanol? | 17:57 |
| juri_ | nein. | 17:57 |
| juri_ | ;) | 17:57 |
| cakeboss | Ah. | 17:57 |
| cakeboss | My brothers speak german. I have been wanting to learn. | 17:57 |
| -!- juri_ was kicked from ##hplusroadmap by kanzure [;)] | 17:57 | |
| cakeboss | aha. | 17:57 |
| @kanzure | i hate this guy | 17:58 |
| cakeboss | haha. | 17:58 |
| -!- juri_ [juri@funkykitty.net] has joined ##hplusroadmap | 17:58 | |
| juri_ | supengo wa iie wakarimashita. | 17:58 |
| juri_ | stop that. :P | 17:58 |
| strangewarp | oh my god what am I even reading | 17:58 |
| juri_ | three hackers, one irc channel? | 17:59 |
| juri_ | my german skills are so old as to be near-useless. i learned english afterward, forgot german, and am still studying japanese. | 18:00 |
| juri_ | so, my linguistic slant is all kinds of sideways. | 18:00 |
| nmz787 | haxx0rs | 18:11 |
| nmz787 | oO | 18:11 |
| -!- cakeboss is now known as onethreethreesev | 18:11 | |
| -!- onethreethreesev is now known as cakeboss | 18:11 | |
| nmz787 | ai ai ai, que paso y'all, es grasa albert | 18:17 |
| cakeboss | jajaja | 18:21 |
| cakeboss | Damn albert grasa que necesita para bajar de peso | 18:21 |
| nmz787 | que? | 18:21 |
| cakeboss | "Damn fat albert you need to lose some weight" | 18:21 |
| nmz787 | :) | 18:22 |
| nmz787 | traductor Google es bueno | 18:22 |
| cakeboss | Nope.avi | 18:22 |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Read error: Connection reset by peer] | 18:22 | |
| cakeboss | I learned spanish in colombia | 18:22 |
| cakeboss | y ecuador | 18:22 |
| nmz787 | how would you detect a virus in linux | 18:23 |
| nmz787 | or rather, a linux virus | 18:23 |
| nmz787 | all i know is clamav | 18:23 |
| cakeboss | nmz787: in terminal type, "rm -f /" | 18:24 |
| -!- armitage81 [~armitage@nemo.centos6server.com] has joined ##hplusroadmap | 18:24 | |
| nmz787 | ahh, yeah that worked! | 18:24 |
| nmz787 | i guess that's not your field of intrusion detection, eh? | 18:25 |
| cakeboss | No, I am actually very skilled in detecting/removing viruses. I don't use software, none that I don't make anyways. | 18:26 |
| juri_ | I've trained clamAV to remove a virus before. pretty simple. | 18:31 |
| yashgaroth | haha what the hell is going on in this channel | 18:58 |
| cakeboss | yashgaroth: propane and propane accessories | 19:00 |
| cakeboss | nmz787: fyi, you wont get a virus in linux unless you are logged in a root...not usually. | 19:12 |
| @kanzure | ... | 19:13 |
| cakeboss | kanzure: unless its something cross platform... | 19:14 |
| cakeboss | kanzure: I assume you use linux, how many viruses have you gotten? | 19:14 |
| @kanzure | i have a couple of GB of collected samples | 19:15 |
| cakeboss | Then you are a moron | 19:15 |
| @kanzure | or a security researcher | 19:15 |
| cakeboss | or that | 19:15 |
| @kanzure | you're full of shit | 19:15 |
| cakeboss | no, you | 19:15 |
| cakeboss | kanzure: for the average linux user I highly doubt there are many infections at all. | 19:16 |
| @kanzure | "as long as you're not root, you're safe" is bad | 19:17 |
| @kanzure | for instance, root exploits | 19:18 |
| cakeboss | Well, no shit. Here is my thing though, unless they are torrenting, connected to networks that have infected computers, or going to sketch sites, they are fine. | 19:18 |
| cakeboss | There is no reason they would get a virus otherwise. | 19:18 |
| cakeboss | I am not saying its impossible, I am saying that in order to get infected someone has to give it to you. If you don't put yourself in that situation you are normally fine. | 19:19 |
| cakeboss | kanzure: http://www.unixmen.com/meet-linux-viruses/ | 19:21 |
| -!- lichen [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has joined ##hplusroadmap | 19:25 | |
| -!- sivoais [~zaki@199.19.225.239] has quit [Ping timeout: 245 seconds] | 19:29 | |
| nmz787 | cakeboss: i never said what i was or wasn't doing, as root or otherwise | 19:36 |
| nmz787 | but yes i was thinking of torrent related stuff | 19:36 |
| nmz787 | like what kind of exploits might already exist out there | 19:36 |
| cakeboss | nmz787: most of them are kernel related | 19:39 |
| cakeboss | nmz787: If it is a distro that is a splinter of any ubuntu version it will most likely be a DDoS vulnerability for the kernel | 19:39 |
| -!- armitage81 [~armitage@nemo.centos6server.com] has quit [Quit: Saliendo] | 19:42 | |
| nmz787 | i didn't know people based distros on ubuntu no | 19:43 |
| nmz787 | now | 19:43 |
| cakeboss | nmz787: blackbuntu, backtrack are the two splinters I am most familiar with. There are an array of others. | 19:43 |
| -!- delinquentme_ [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 20:06 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 244 seconds] | 20:09 | |
| -!- ParahSailin_ [~parah@adsl-69-151-150-200.dsl.hstntx.swbell.net] has joined ##hplusroadmap | 20:24 | |
| -!- ParahSailin [~parah@unaffiliated/parahsailin] has quit [Read error: Connection reset by peer] | 20:24 | |
| -!- Shehrazad is now known as ElixirVitae | 21:07 | |
| -!- xlhl [~patrickgr@pool-98-111-56-213.sctnpa.east.verizon.net] has joined ##hplusroadmap | 21:25 | |
| -!- mgodinho [~user@pdpc/supporter/active/mgodinho] has joined ##hplusroadmap | 21:37 | |
| xlhl | hello mgodinho | 21:46 |
| xlhl | what are your interests here? | 21:46 |
| @kanzure | yashgaroth: this one has questions about synthetic proteins or something | 21:47 |
| yashgaroth | who does | 21:48 |
| @kanzure | patrickgrunkle | 21:48 |
| yashgaroth | hokay then | 21:48 |
| @kanzure | grinaway, i mean | 21:48 |
| @kanzure | damn. | 21:48 |
| * kanzure goes back to sleep | 21:48 | |
| xlhl | yeah i am interested in synthetic protein interaction networks | 21:49 |
| yashgaroth | as in, interactions between synthetic proteins, or calling interaction networks 'synthetic' | 21:49 |
| xlhl | calling interaction networks synthetic, i presume. i'm not sure what synthetic proteins would really accomplish (unless we are talking about protein engineering) | 21:50 |
| xlhl | i am interested in altering/creating protein signaling pathways | 21:50 |
| yashgaroth | well that's gonna be protein engineering | 21:50 |
| xlhl | yeah | 21:50 |
| xlhl | i think protein kinase networks are very interesting, i suppose engineering them would involve an understanding of how the kinases recognize their targets | 21:51 |
| yashgaroth | we have an idea of how they recognize targets...like with most protein interactions, you've got mostly electrostatic attraction, and then a phosphate donation to a hydroxyl | 21:53 |
| yashgaroth | but that doesn't really tell you how to make one | 21:54 |
| xlhl | yeah it strikes me as a sort of molecular docking problem? | 21:54 |
| yashgaroth | and retaining that binding during the phosphorylation, while modifying the surrounding amino acids so it actually binds your intended target | 21:55 |
| yashgaroth | idk I'm sure a good review of GPCRs would cover the topic pretty well | 21:57 |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Read error: Connection reset by peer] | 21:57 | |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has joined ##hplusroadmap | 21:57 | |
| yashgaroth | if they can bind to thousands of ligands and signaling proteins, anything can | 21:58 |
| xlhl | yeah GPCRs are pretty versatile | 21:59 |
| xlhl | as are immunoglobulins | 21:59 |
| xlhl | though i guess downstream GPCRs have many more targets | 21:59 |
| yashgaroth | sure but IGs get the benefit of nearly infinite mutation | 22:00 |
| xlhl | well GPCRs are very varied as well, I haven't tried a sequence alignment but I assume there is considerable diversity | 22:00 |
| xlhl | so over evolutionary time scales they get to accumulate mutations as well | 22:01 |
| yashgaroth | oh totally, but not like IGs do | 22:01 |
| xlhl | gotcha. I'm an EE by training, just started with systems biology | 22:01 |
| xlhl | so bear with my potential errors in biology | 22:02 |
| yashgaroth | IGs get recombined in every immune cell after you're born | 22:02 |
| yashgaroth | GPCRs have a lot of diversity but it's all heritable, unlike IGs | 22:03 |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Ping timeout: 244 seconds] | 22:03 | |
| yashgaroth | but yes they are both cool and unique | 22:05 |
| mgodinho | xlhl: hello, you meant my interests here? | 22:05 |
| xlhl | yeah, i just figured i'd start something :P | 22:06 |
| xlhl | they are. actually, on the topic of GPCRs, it would be cool to use them as biosensors | 22:06 |
| xlhl | though I imagine expressing them in another organism might be difficult | 22:06 |
| mgodinho | xlhl: right ;) i bit bioinfo, tools for synthetic bio, more on the DIY side | 22:07 |
| yashgaroth | well you'd have to use eukaryotes to express gpcrs, but that doesn't limit you terribly | 22:07 |
| xlhl | right, so maybe yeast | 22:08 |
| xlhl | since that seems to be the easiest eukaryote to work with | 22:08 |
| yashgaroth | yeah yeast are great | 22:08 |
| xlhl | i was recently working with 293T and yeast seem much easier :P | 22:08 |
| xlhl | mgodinho: cool, the diy stuff interests me as well | 22:09 |
| yashgaroth | oh man 293s are like the easiest mammalian cells | 22:09 |
| xlhl | this should be fun then | 22:09 |
| xlhl | :P | 22:09 |
| juri_ | document, document, document! ;) | 22:10 |
| xlhl | have you worked with K562? I have to deal with those at some point | 22:10 |
| xlhl | :P | 22:10 |
| yashgaroth | not that I know of but it might have been in some multi-cancer screen plate | 22:10 |
| xlhl | ah understood. i suppose the only thing about 293T that annoyed me is their quasi-attachment | 22:11 |
| xlhl | at least the transfection was easy | 22:11 |
| yashgaroth | indeed, you'll be happy to work with yeast then; and the media costs about 100 times less | 22:12 |
| xlhl | yeah, and no need for the 5% CO2 incubator, right? | 22:12 |
| yashgaroth | that too | 22:13 |
| yashgaroth | what types of molecules are you interested in biosensing? | 22:13 |
| xlhl | small organic molecules, common pollutants | 22:14 |
| xlhl | i guess one might be able to use bacteria for that as well, using one of their transcriptional regulators that responds to the compound of interest | 22:14 |
| yashgaroth | would be the far easier method | 22:15 |
| xlhl | yeah | 22:15 |
| xlhl | bacteria have those cell surface receptors too (receptor histidine kinases?) but idk how much is known about them | 22:15 |
| yashgaroth | depending on how small the molecules are, they may just float into the cell at a sufficient level | 22:16 |
| xlhl | thats true | 22:16 |
| yashgaroth | unless you've got a pollutant that's already known to bind to some GPCR or whatever, though, you'll have a long road ahead of you | 22:18 |
| xlhl | i don't have a very good sense of the timescale of directed evolution with GPCRs, i guess it would be very tedious | 22:19 |
| yashgaroth | ten years in a well-equipped lab | 22:19 |
| xlhl | well, that's pretty intense | 22:20 |
| yashgaroth | the timescales are coming down, slowly | 22:21 |
| yashgaroth | but yes generally it's not feasible unless you're going after them sweet sweet cancer moniez | 22:21 |
| xlhl | yeah i've realized that | 22:21 |
| xlhl | cancer is interesting but there is so much more to biology | 22:22 |
| xlhl | :P | 22:22 |
| xlhl | though my recent limited experience with cell culture comes from working in a cancer lab, so there's that | 22:23 |
| yashgaroth | it definitely keeps biologists employed | 22:23 |
| xlhl | yeah | 22:23 |
| xlhl | well im going to head off to bed. it was nice talking to you, thanks | 22:25 |
| yashgaroth | sure thing, come back soon | 22:26 |
| xlhl | will do | 22:26 |
| -!- xlhl [~patrickgr@pool-98-111-56-213.sctnpa.east.verizon.net] has left ##hplusroadmap [] | 22:26 | |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has joined ##hplusroadmap | 22:45 | |
| -!- Mariu [Jimmy98@89.41.57.33] has joined ##hplusroadmap | 23:34 | |
| -!- abetusk [~abetusk@cpe-24-58-232-122.twcny.res.rr.com] has joined ##hplusroadmap | 23:37 | |
| -!- delinquentme_ [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 244 seconds] | 23:37 | |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Ping timeout: 244 seconds] | 23:44 | |
| nmz787 | i want to design a GPCR-based biosensor using a serotonin receptor | 23:57 |
| nmz787 | then i could do TLC on random stuff and easily see if it might be interesting | 23:58 |
| yashgaroth | well that should be relatively easy | 23:58 |
| nmz787 | i hadn't seen any good examples of taking human GPCR and linking it to GFP production, etc | 23:59 |
| nmz787 | GPCR reporter | 23:59 |
| --- Log closed Sat Nov 24 00:00:25 2012 | ||
Generated by irclog2html.py 2.15.0.dev0 by Marius Gedminas - find it at mg.pov.lt!