| --- Log opened Mon Jan 21 00:00:36 2013 | ||
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| eleitl | good morning | 01:14 |
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| @kanzure | eleitl: hi | 01:41 |
| eleitl | rehi | 01:41 |
| nmz787 | hi | 02:08 |
| nmz787 | eleitl: Dr. Ramsey, | 02:08 |
| nmz787 | I've recently moved to Hillsboro, OR, and even toured the FEI NanoPort | 02:08 |
| nmz787 | Showroom last week with the local ACS chapter. I applied to the | 02:08 |
| nmz787 | Chemistry Ph.D. program at Portland State University, and I'd like to | 02:08 |
| nmz787 | focus on optimizing high-throughput DNA synthesis on a micro or | 02:08 |
| nmz787 | nano-fluidic platform. | 02:08 |
| nmz787 | I was told by a professor there, Dr. Albert S Benight, that I'd have | 02:08 |
| nmz787 | to find a funding if I wanted to do my own project. I've searched on | 02:08 |
| nmz787 | grants.gov and think I might be able to fit into some biodefense area, | 02:08 |
| nmz787 | making DNA primers de-novo for portable bioagent detection or | 02:08 |
| nmz787 | something, but I don't know where to look otherwise. | 02:08 |
| nmz787 | Do you have any ideas? | 02:08 |
| nmz787 | whoops | 02:08 |
| nmz787 | wrong paste buffer | 02:08 |
| eleitl | np | 02:08 |
| nmz787 | i responded to you on diybio eleitl | 02:09 |
| eleitl | Thanks, Nathan! | 02:09 |
| eleitl | not sure the materials can take, e.g. DMSO/ethanediol/DMF are very good solvents for many polymers | 02:10 |
| eleitl | microfluidics would work well, but it has to be glass/ceramics/metal | 02:11 |
| eleitl | I was thinking about driving a valve with PWM | 02:11 |
| eleitl | mixing via duty cycle | 02:11 |
| eleitl | then, pipe it through nonlinear mixer | 02:12 |
| nmz787 | you can do glass microfluidics | 02:14 |
| eleitl | yes, but not with the stuff we have | 02:14 |
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| nmz787 | eleitl: http://nathanmccorkle.com/pdf/Rapid%20prototyping%20of%20glass-based%20micro%ef%ac%82uidic%20chips%20utilizing%20two-pass%20defocused%20CO2%20laser%20beam%20method.pdf | 02:15 |
| nmz787 | CO2 laser | 02:15 |
| eleitl | we don't have a laser, either | 02:16 |
| eleitl | we need to buy a number of project-related items | 02:16 |
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| eleitl | CCC has a makerspace, but I think it's pretty barebones | 02:16 |
| nmz787 | ahh, I just saw a link for a place that was charging $35/hour of CO2 laser time | 02:16 |
| eleitl | not sure, need to check | 02:16 |
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| * eudoxia checks the logs | 04:12 | |
| eudoxia | i'm glad kim suozzi made it | 04:12 |
| eudoxia | and she got to alcor instead of ci | 04:12 |
| eleitl | I'm also glad | 04:21 |
| eleitl | I hope the tumor did not destroy too much | 04:21 |
| eudoxia | we'll have to wait for the report | 04:23 |
| eudoxia | then she goes on the list :( | 04:23 |
| eleitl | I've seen her original comment on reddit | 04:24 |
| eleitl | thought -- damn, another one of these hopeless cases | 04:24 |
| eleitl | glad milk of human kindness still hasn't run out | 04:25 |
| eleitl | http://www.jove.com/ <-- have been living under a rock, first time I see this | 04:26 |
| eudoxia | i thought she was gonna make it to CI | 04:32 |
| eudoxia | then ben best would do what he did to Henderson or something | 04:32 |
| eudoxia | absolutely horrifying | 04:33 |
| eleitl | are you reading the new cryonet? | 04:41 |
| eudoxia | ocassionally | 04:41 |
| eleitl | marta sandberg is rapidly becoming a major troll | 04:41 |
| eudoxia | ocasionally* | 04:41 |
| eleitl | are you actually from uruguay? | 04:41 |
| eudoxia | oh i noticed | 04:42 |
| eudoxia | and yes | 04:42 |
| eleitl | which part? big city? | 04:42 |
| eudoxia | montevideo, moderately | 04:42 |
| eleitl | do you like it there? | 04:42 |
| eudoxia | it's rather nice | 04:43 |
| eudoxia | still planning to escape as soon as possible | 04:43 |
| eleitl | some people consider uruguay a potential location to emigrate to | 04:43 |
| eudoxia | because it will be relatively untouched when the Happening happens, or some other reason? | 04:44 |
| eleitl | does it get very hot in the summer? | 04:45 |
| eudoxia | not australia hot | 04:45 |
| eudoxia | right now its kind of chilly | 04:45 |
| eleitl | any technology scene there? what does a hacker do in montevideo? | 04:46 |
| eudoxia | well there's a pycon | 04:47 |
| eudoxia | and the engineering uni hosts a robot sumo every year | 04:48 |
| eudoxia | and that's about it | 04:48 |
| eleitl | where woult you escape to, if you could? bay area? | 04:48 |
| eudoxia | any part of america that's not too expensive or too baby jesus-y | 04:49 |
| eudoxia | america = US | 04:49 |
| eleitl | I see | 04:50 |
| eleitl | I would probably move to .no or .ch, if I could | 04:50 |
| eudoxia | .ch seems nice | 04:52 |
| eudoxia | it has the LHC and no crime | 04:53 |
| eudoxia | my godmother keeps telling me i should go study at the KTH | 04:55 |
| eudoxia | where she went | 04:56 |
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| eleitl | ETH? | 05:00 |
| eleitl | nice place | 05:00 |
| eleitl | Eidgenoessische Technische Hochschule | 05:00 |
| eudoxia | no the http://en.wikipedia.org/wiki/Royal_Institute_of_Technology | 05:01 |
| eleitl | oh, .se | 05:01 |
| eleitl | Ander's place | 05:01 |
| eleitl | Anders' | 05:01 |
| eleitl | damn, it's down | 05:02 |
| eudoxia | oh god aleph.se is down | 05:02 |
| eleitl | yes, I just noticed | 05:03 |
| eudoxia | the end times are upon us | 05:03 |
| eudoxia | well actually it happens from time to time | 05:03 |
| eudoxia | i always think "this is it, it's down for good" | 05:03 |
| eleitl | state: deactivated | 05:04 |
| eleitl | domain: aleph.se | 05:04 |
| eleitl | deactivationdate: 2013-01-21 | 05:04 |
| eleitl | date_to_delete: 2013-03-22 | 05:04 |
| eleitl | date_to_release: 2013-03-29 | 05:04 |
| eudoxia | this is it | 05:04 |
| eudoxia | 1996 - 2013 | 05:05 |
| eleitl | will you ping him I should I do it? | 05:05 |
| eudoxia | he knows you | 05:06 |
| eleitl | great, we've got another 500 EUR budget for purchases approved | 05:06 |
| eleitl | I'll ping him, then. | 05:06 |
| eudoxia | well at least the Archive has it | 05:06 |
| eudoxia | and i recursively downloaded everything a while ago | 05:06 |
| eudoxia | or did kanz do that... | 05:06 |
| eudoxia | http://diyhpl.us/~bryan/irc/anders/backup_anders.tar.gz | 05:07 |
| eleitl | did you knew of jove.com before? | 05:08 |
| eudoxia | nope | 05:09 |
| eleitl | ok, then I haven't completely jumped the shark yet | 05:09 |
| eleitl | eudoxia, do you have an OpenQwaq account? | 05:11 |
| eudoxia | no | 05:11 |
| eudoxia | that's where all the cool extropians meet up? | 05:11 |
| eleitl | do you need one? | 05:11 |
| eleitl | it's Giulio Prisco's server, | 05:12 |
| eleitl | Ron Teitelbaum allows us to use it for events, and such | 05:12 |
| eleitl | I can invite you if you give me a working email address | 05:13 |
| eleitl | thanks, invite sent | 05:14 |
| eudoxia | thanks | 05:14 |
| eleitl | clients work on windows, OS X, and Linux, latter only somewhat | 05:14 |
| eleitl | the login details should be in the mail | 05:14 |
| eudoxia | that's the same place where ken hayworth made that talk about the atlum right? | 05:14 |
| eleitl | right | 05:15 |
| eudoxia | or is it 'did'... | 05:15 |
| eleitl | it has very good audio and video conferencing, especially if you have a headset | 05:15 |
| eleitl | are you win, os x or linux? | 05:15 |
| eudoxia | linux, and i have a yellowed microsoft and headphones :3 | 05:15 |
| eleitl | not sure the linux client would do decent codecs | 05:16 |
| eleitl | just try it, I guess | 05:16 |
| eudoxia | i have win7 on the other partition | 05:16 |
| eleitl | win7 works good | 05:16 |
| eleitl | http://code.google.com/p/openqwaq/downloads/list <-- looks a bit long in the tooth | 05:17 |
| eleitl | not sure the 3dicc client is fresher | 05:17 |
| eleitl | use the 3dicc client unless told otherwise | 05:17 |
| eleitl | this technology is based on Smalltalk (Squeak)/OpenCroquet/OpenCobalt/TelePlace etc. | 05:18 |
| eudoxia | i heard | 05:18 |
| eleitl | they're rewriting it in JavaScript, so that it will run in a browser | 05:18 |
| eleitl | not sure it's a smart idea | 05:18 |
| eudoxia | never imagined squeak being used for something serious | 05:18 |
| eudoxia | wait i was thinking about something else | 05:19 |
| eleitl | all the Smalltalk coders are pretty much dead, it seems | 05:19 |
| eleitl | I'm in-world, but at work, so no video, and not a full presence there | 05:20 |
| eleitl | It is nice to see that both of you reacted within 3 minutes of each other. True friends keep an eye on each other's domains :-) | 05:42 |
| eleitl | I think it is a minor payment bug, occasionally I do not get the bills in time in England. I have emailed FSData, my Swedish ISP. | 05:42 |
| eleitl | Have no fear, aleph will be back! | 05:42 |
| eleitl | </anders> | 05:42 |
| eudoxia | i gotta say we have a better response time than a NATO early warning station | 05:44 |
| eleitl | :) | 05:45 |
| eleitl | our co-worker is from Peru, she hasn't been to Montevideo but has seen it from Buenos Aires once | 05:47 |
| eleitl | according to Google, Uruguay looks really nice | 05:47 |
| eudoxia | oh yes | 05:48 |
| eudoxia | a peruvian cryonicist? that's fairly new | 05:48 |
| eleitl | no, she does Java at my dayjob, InfoChem GmbH | 05:49 |
| * eleitl is at the accursed saltimes | 05:49 | |
| eleitl | saltmines even | 05:49 |
| eudoxia | on the subject of chemistry | 05:50 |
| eudoxia | have you seen github.com/kanzure/nanoengineer | 05:50 |
| eleitl | I see it now. What new is there? | 05:51 |
| eudoxia | kanz is trying to bring it back, an kirka/elfion managed to run it on linux | 05:52 |
| eleitl | 64 bit? | 05:52 |
| eudoxia | i think so | 05:52 |
| eleitl | I have 12.04 at home, I should try it sometime | 05:52 |
| eleitl | it would be great to have a bunch of packages, or even a depository | 05:53 |
| eudoxia | for molecular machine parts? | 05:53 |
| eleitl | no, just for nanoengineer | 05:53 |
| eudoxia | oh like a deb package | 05:53 |
| eleitl | of course a parts depository would be great, too | 05:53 |
| eleitl | a kind of molecular logo/macros with standard interfaces | 05:54 |
| eleitl | I'll go tell Perry, though he probably already knows | 05:55 |
| eudoxia | it might be possible to, as kirka suggested, abstract some machines into blocks with only external bondpoints | 05:56 |
| eudoxia | might need a specialized simulator thoguh | 05:56 |
| eleitl | you need a drag forcefield, which is basically bitblt at voxel level, with collision detection | 05:57 |
| eleitl | that's the only way to drag big blocks quickly | 05:57 |
| eleitl | dammit, I don't even have a working account for perry anymore | 06:00 |
| eleitl | jis.mit.edu bounces | 06:00 |
| eleitl | which kind of Internet hoster do you use, eudoxia? Or just a regular ISP? | 06:04 |
| eudoxia | regular | 06:05 |
| eleitl | colocation in uruguay is probably a bit expensive | 06:06 |
| eleitl | in fact, since my hoster started charging rent for IP space, I'll be moving kit and kaboodle to a local hoster | 06:07 |
| eleitl | how likely do you think is the 2030 peak? http://www.smithsonianmag.com/science-nature/Looking-Back-on-the-Limits-of-Growth.html | 06:19 |
| eleitl | the curves look like it could shift more towards 2040, but that is too far to be very accurate | 06:20 |
| eudoxia | undersea mining will hold back the Happening for a few years | 06:22 |
| eleitl | if we're energy-limited, then EROEI going to shit then new fossil is worth much old than the less | 06:22 |
| eleitl | we've gone from 100:1 to 25:1 and lower. | 06:23 |
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| eudoxia | we're gonna miss oil | 06:25 |
| eleitl | we already do | 06:27 |
| eleitl | things would look a lot prettier with 20 USD/barrel right now | 06:27 |
| eleitl | on the other hand, Chinese would really need axes to cut through the smog, then | 06:28 |
| eudoxia | haha | 06:28 |
| eudoxia | it's rather sad | 06:28 |
| eleitl | friends go there yearly, for visa reasons, and they have to live smack in Peking. With kids. Not fun. | 06:29 |
| eudoxia | maybe it will be an incentive to speed up the thorium reactor project | 06:30 |
| eleitl | if it's feasible, it would take too long | 06:30 |
| eleitl | min 30 years | 06:31 |
| eleitl | assuming it's feasible, which we don't know | 06:31 |
| eleitl | too risky | 06:31 |
| eleitl | I do really think uruguay will be far enough from all the crap that's going to go down | 06:31 |
| eleitl | South America and Oz/Kiwiland will probably sit quite pretty | 06:32 |
| eudoxia | >Its ultimate target is to develop a pilot scale thorium based molten salt nuclear reactor in 20 years. | 06:32 |
| eudoxia | oh come on china you can do better | 06:32 |
| eleitl | no, nuclear tech doesn't happen quickly | 06:32 |
| eleitl | 20 years is already more ambitious, and I doubt they can pull it off without sacrificing something | 06:33 |
| eleitl | THTR in Germany was shut down due to a series of technical problems, and they're starting with a graphite ball pile | 06:33 |
| eleitl | if they run into difficulties there, chances are they won't do MSR at all | 06:33 |
| archels | Do you think ITER is going to work out, eleitl? | 06:33 |
| eleitl | plus, there's a problem with U233 inventory. You need some 2-3 tons in-core. | 06:34 |
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| eleitl | You might be able to kickstart a thorium fuelcycle breeder with Pu-239 of which there's a metric crapload, but I don't know. | 06:34 |
| eleitl | let's say we need 1000 reactors/year, that's some 3000 tons of Pu-239. | 06:35 |
| eleitl | that assuming you can build 1000 ~GW reactors/year. | 06:35 |
| eudoxia | hm | 06:35 |
| eudoxia | all those cold war era icmbs aren't gonna cut it | 06:35 |
| eleitl | wouldn't work with current pressurized water type at all | 06:36 |
| eudoxia | ICBMs* | 06:36 |
| eleitl | you'll probably have to reprocess all the spent fuel rods | 06:36 |
| eudoxia | i'm gonna send these logs to my friend who is a thorium friend | 06:37 |
| eudoxia | freak* | 06:37 |
| eleitl | http://www.ccnr.org/plute_inventory_99.html <-- pure Pu is really rare, so you have to reprocess spent fuel | 06:37 |
| eleitl | that is also a bottleneck | 06:38 |
| JayDugger | Good morning, everyone. | 06:38 |
| eleitl | good morning | 06:39 |
| eleitl | long time no talk | 06:39 |
| JayDugger | Marriage and a job will do that. :) | 06:39 |
| eleitl | http://atomicinsights.com/2012/06/there-are-three-superfuels-uranium-thorium-and-plutonium.html | 06:39 |
| eleitl | ... No, you have this backwards. Fast-spectrum U-Pu reactors need high fissionable inventories due to the low fission cross-section at high energies; despite high breeding ratios (1.22 for PRISM) if you are only producing 0.22 additional ton of Pu out of ~7.5 tons total fuel-cycle inventory (in-core, cooling and reprocessing), your rate of increase is under 3%/yr and your doubling time is upwards of 25 years. | 06:40 |
| eleitl | LFTR can apparently hit breeding ratios of 1.05-1.07 at reasonable cost, and has no inventory requirement for cooling or fabrication. More to the point, the thermal spectrum reactor has a low fissionable inventory; it can have a burnup of 80-100% per year. Increase at 4%/year doubles in 17 years, 5.6%/year doubles in 12.5 years, 7%/year takes 10. | 06:40 |
| JayDugger | And then I had to quickly catch up on the logs, too. | 06:40 |
| eleitl | This still leaves us with the Pu/Am/Cm from a host of sources, even if a substantial amount of it is burned as the starting fuel charges for LFTRs. Fast-spectrum reactors will get rid of it, burn our abundant supply of DU that we should not waste, and also take the waste Np-238 that LFTRs are inevitably going to have to do something with. The two go hand in hand. | 06:40 |
| eleitl | Not sure what to make of it, atomicinsights is a worthless blog usually. | 06:41 |
| eleitl | in any case you won't get the scale up kinetics, even if it would all work, which we don't know | 06:41 |
| eleitl | I'm afraid we now have to use the only technology we already have, and which can be scaled up quickly | 06:42 |
| eleitl | archels, I think ITER will be canceled, or delayed indefinitely | 06:43 |
| eleitl | very little money left | 06:43 |
| archels | I didn't know it was in such stormy weather. Hard to keep up a project with so many stakeholders over the course of a few decades, I guess. | 06:45 |
| archels | NIF suffered the same fate, last I heard | 06:45 |
| eudoxia | fusion will always be 50 years away | 06:45 |
| eleitl | they did not plan with the current economic winter, which I fear will be semi-permanent | 06:45 |
| eleitl | if we have zero growth or outright contraction for the next 30-40 years, most ambitious projects will be killed | 06:46 |
| eleitl | this includes space | 06:46 |
| eleitl | not a future I grew up expecting | 06:46 |
| archels | The NIC officially ended on September 30, 2012 without achieving ignition. According to numerous articles in the press, Congress is concerned about the project's progress and funding arguments may begin anew.[106][107][108] These reports also suggest that NIF will shift its focus away from ignition back toward materials research. | 06:47 |
| eudoxia | National Ignition Facility is quite the kickin' name | 06:48 |
| eleitl | apparently inertial confinement hit unexpected physics | 06:49 |
| eleitl | just as tokamaks did | 06:49 |
| eleitl | nature doesn't want us to win easily | 06:49 |
| eleitl | where are you now, JayDugger? | 06:51 |
| JayDugger | Texas, just north of Dallas. | 06:52 |
| JayDugger | No more traveling for me. The job's mindless, but steady, and strictly 40 hrs/week. | 06:52 |
| JayDugger | Much better than when last we spoke. | 06:52 |
| eleitl | Same thing here. | 06:53 |
| JayDugger | Job-wise, I assume? | 06:53 |
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| eleitl | I try to make it more interesting, by myself. | 06:53 |
| eleitl | Yes. We've also started a local cryonics lab, which takes up a lot of time. | 06:53 |
| eleitl | Will be writing SENS grant applications in a week or two. | 06:54 |
| JayDugger | Good and good! | 06:54 |
| eleitl | we burn through 1 kEUR/month just for rent, need to cross-fund this, and time-share the place. | 06:54 |
| eleitl | apart from that we're doing some Zero State things, which might or might not succeed | 07:01 |
| JayDugger | I haven't heard of Zero State. | 07:02 |
| eudoxia | i heard a little | 07:02 |
| eleitl | it's a new organization http://zerostate.net/ | 07:02 |
| JayDugger | Saw that in the Google results, I'll look. | 07:03 |
| eudoxia | it looked a tiny bit cultish, but i haven't looked into it | 07:03 |
| eleitl | we've had a meeting in May at my place last year, but it's mostly UK based | 07:03 |
| eleitl | yeah, it has to be somewhat cultish to be sticky | 07:03 |
| eleitl | it's basically a variation on the transhumanist memeplex packaging | 07:04 |
| eleitl | ExI tanked, but this doesn't mean it's intrinsically nonsticky | 07:04 |
| eudoxia | and something called kalkinism | 07:04 |
| eleitl | the founder's nym is Amon Kalkin | 07:05 |
| eudoxia | i think that's what set off my cult alarm | 07:05 |
| eleitl | mine, too :) | 07:05 |
| eudoxia | oh i thought that was his legal name, like he'd changed it | 07:06 |
| eleitl | there are a number of projects, one of them could be even quite successfull | 07:06 |
| eleitl | but, nobody to know what it is ;) | 07:06 |
| eudoxia | the classifier in my head reported 3.5 Rachel Haywires of cultism | 07:06 |
| eleitl | is that a logarithmic scale? | 07:07 |
| eudoxia | no | 07:07 |
| eleitl | Rachel seems to be into emo transhumanism | 07:10 |
| eleitl | I must admit I do not care much for that | 07:10 |
| eudoxia | she used to be the editor of h+ magazine | 07:10 |
| eudoxia | the horro | 07:10 |
| eudoxia | horror* | 07:10 |
| eleitl | I haven't touched anything WTA in a long time | 07:11 |
| eudoxia | you haven't missed anything of value | 07:12 |
| eleitl | I know, I'm actively staying away | 07:12 |
| eleitl | by the way, Giulio is also in-world, and Natasha will be coming | 07:24 |
| eleitl | JayDugger, have you used OpenQwaq or Teleplace? | 07:26 |
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| eleitl | whoah, a quarter-second ping to eudoxia | 07:39 |
| eleitl | panax seems to hail from florida | 07:41 |
| eleitl | any of you do DIYbio? | 07:46 |
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| eleitl | the antiperks of hailing from GMT+1, I guess. | 07:49 |
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| eleitl | rehi eudoxia | 07:59 |
| eudoxia | hi | 07:59 |
| eleitl | I've got a 254 ms ping to you from Nuremberg | 07:59 |
| eleitl | but extremely constant. traceroute shows 13 hops. | 08:00 |
| eudoxia | work internet, probably accounts for 25% of this country's bandwidth | 08:00 |
| eleitl | connection looks good | 08:01 |
| eleitl | I've had to resort to reading imgur, out of boredom | 08:01 |
| eudoxia | but it's monday. xkcd, smbc, whomp all update | 08:02 |
| eleitl | how is IPv6 deployment doing in .uy? | 08:05 |
| eudoxia | no idea | 08:05 |
| eleitl | 0.01%, according to Google | 08:07 |
| eleitl | total is 1.12%, and it looks exponential so far | 08:08 |
| eleitl | doubling time is around one year, apparently | 08:10 |
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| @kanzure | eleitl: yes we have diybio peeps in here | 09:43 |
| @kanzure | paperbot: http://www.media.mit.edu/molecular/HamadNature.pdf | 09:44 |
| paperbot | no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/a2fde125ece63c808e66ee539a3691a8.pdf | 09:44 |
| @kanzure | paperbot: http://mnras.oxfordjournals.org/content/early/2013/01/08/mnras.sts378.full | 09:44 |
| paperbot | IOError: [Errno 2] No such file or directory: '/home/bryan/public_html/papers2/paperbot/A Galactic short gamma-ray burst as cause for the 14C peak in AD 774/5.pdf' (file "/srv/ikiwiki/paperbot/modules/papers.py", line 200, in download_url) | 09:45 |
| @kanzure | ah | 09:45 |
| gnusha | https://secure.diyhpl.us/cgit/paperbot/commit/?id=e021c543 Bryan Bishop: make paper titles with slashes work | 09:46 |
| gnusha | paperbot: reload papers | 09:46 |
| paperbot | gnusha: <module 'papers' from '/srv/ikiwiki/paperbot/modules/papers.py'> (version: 2013-01-21 17:46:27) | 09:46 |
| @kanzure | paperbot: http://mnras.oxfordjournals.org/content/early/2013/01/08/mnras.sts378.full | 09:46 |
| paperbot | no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/A%20Galactic%20short%20gamma-ray%20burst%20as%20cause%20for%20the%2014C%20peak%20in%20AD%20774_5.pdf | 09:46 |
| eudoxia | 167 megatonnes | 09:52 |
| eudoxia | could've been worse | 09:52 |
| eleitl | could have been next door | 09:53 |
| eudoxia | 'So the knights in armour were lucky, else they would be walking microwaves' | 09:54 |
| eudoxia | oh facepunch <3 | 09:54 |
| eleitl | gamma fries atmosphere | 09:55 |
| eudoxia | gamma fries everything | 09:55 |
| eudoxia | another reason to live underwater | 09:55 |
| eleitl | apropos fried: I'm off to home. See you. | 09:56 |
| @kanzure | someone suggested living in a supervolcano lair for the obsidian casting potential | 09:56 |
| ParahSai1in | dragonglass | 09:57 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=b10004a3 Bryan Bishop: diybio-seattle link | 13:21 |
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| eudoxia | guys quick | 14:01 |
| eudoxia | how do you call the quality of a tumor being malign or benign? | 14:01 |
| eudoxia | the 'malignity' or just the risk? | 14:01 |
| jrayhawk | malignancy | 14:02 |
| eudoxia | thanks | 14:02 |
| eudoxia | another unrelated question: what does alcor do with the bodies of the neuropreserved? | 14:03 |
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| @kanzure | paperbot: http://www.sciencedirect.com/science/article/pii/S1048984312000811 | 15:23 |
| paperbot | no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Born%20to%20lead%3F%20A%20twin%20design%20and%20genetic%20association%20study%20of%20leadership%20role%20occupancy%20.pdf | 15:23 |
| @kanzure | eww a space at the end of the title. | 15:24 |
| @kanzure | this is the worst | 15:24 |
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| nmz787 | http://www.weather.com/news/neanderthal-baby-surrogate-20130121 | 15:50 |
| nmz787 | paperbot: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=806324&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D806324 | 15:52 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/49822e4f85e6d8dee243898823ce6ea7.txt | 15:52 |
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| jrayhawk | newuser is probably working again | 15:57 |
| jrayhawk | you might want to change /etc/mailname to something more interesting | 15:57 |
| nmz787 | kanzure: check this out http://www.freepatentsonline.com/20130005612.pdf | 16:06 |
| nmz787 | he's checking for addition on single molecules using a fluorophore on the added nucleotide, then passing the growing strand through a nanopore past a spectrometer | 16:08 |
| nmz787 | also using the fluorophore as the protectant (which disallows multiple base addition per step) | 16:09 |
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| nmz787 | "in linear syntheses based on phosphoramidite chemistry, there are many potentioal sources of sequence erreor and oligonucleotide damage that are well documented. Most notable, the removeal of the 5'protecting group usually involves an acidic treatment that can removce the base, or in the case of photolabile 5'protecting group, require UV irradiation that can damage the nucleotide."... the nucleotide may fail to incorporate, nearly all the organic an | 16:14 |
| nmz787 | wow this patent is great | 16:15 |
| Guest62567 | this is just a test | 16:15 |
| Guest62567 | http://www.annualreviews.org/doi/abs/10.1146/annurev.genet.30.1.141 | 16:15 |
| paperbot | IndexError: list index out of range (file "/srv/ikiwiki/paperbot/modules/papers.py", line 65, in download) | 16:15 |
| Guest62567 | dx.doi.org/10.1146/annurev.genet.30.1.141 | 16:16 |
| Guest62567 | www.dx.doi.org/10.1146/annurev.genet.30.1.141 | 16:16 |
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| Guest62567 | http://dx.doi.org/10.1146/annurev.genet.30.1.141 | 16:17 |
| Guest62567 | http://informahealthcare.com/doi/abs/10.3109/03008200903349639 | 16:18 |
| Guest62567 | http://www.sciencedirect.com/science/article/pii/S106573559800011X | 16:20 |
| Guest62567 | paperbot: http://www.sciencedirect.com/science/article/pii/S106573559800011X | 16:21 |
| paperbot | no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Processing_property_structure%20interactions%20in%20a%20calcium%20aluminate-phenol%20resin%20composite.pdf | 16:21 |
| nmz787 | paperbot: ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=806324&tag=1 | 16:37 |
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| gnusha | https://secure.diyhpl.us/cgit/paperbot/commit/?id=2c3df4e2 Bryan Bishop: handle ieee xplore login.jsp urls | 17:13 |
| gnusha | paperbot: reload papers | 17:13 |
| paperbot | gnusha: <module 'papers' from '/srv/ikiwiki/paperbot/modules/papers.py'> (version: 2013-01-22 01:13:21) | 17:13 |
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| @kanzure | paperbot: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=806324&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D806324 | 17:14 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/8462b4826166058e9cb89f764fce2db5.txt | 17:14 |
| @kanzure | well.. that sort of worked. | 17:14 |
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| @kanzure | jrayhawk: thank you | 17:16 |
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| @kanzure | jrayhawk: any thoughts about unbreaking the git service? | 17:17 |
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| @kanzure | nmz787: that's one of the guys doing gen9bio.com | 17:18 |
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| @kanzure | http://www.nature.com/news/bloggers-put-chemical-reactions-through-the-replication-mill-1.12262 | 17:25 |
| @kanzure | "The other team members include chemistry graduate student Matt Katcher from Princeton, New Jersey, and two bloggers called Organometallica and BRSM" | 17:25 |
| @kanzure | organometallica. | 17:25 |
| @kanzure | did not know this "The journal Organic Syntheses, for example, only publishes synthetic procedures that have been checked and verified by a member of its editorial board." | 17:26 |
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| @kanzure | not sure why they are trotting out chemspider though, that thing is uber-proprietary | 17:26 |
| @kanzure | there's only one post? | 17:27 |
| @kanzure | http://blog-syn.blogspot.co.uk/2013/01/blog-syn-001-iron-sulfur-catalysis.html | 17:27 |
| @kanzure | seems like the barriers to get into nature news have uh lessened | 17:27 |
| Vicarious | ohai | 17:42 |
| barriers | u rang | 17:46 |
| nmz787 | damn I missed a relevant conference http://www.chi-peptalk.com/Genes-Vectors-Clones | 18:01 |
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| eudoxia | well kim's entry is up http://wiki.transhumani.com/index.php?title=Cryonics#Kim_Suozzi | 18:05 |
| eudoxia | this list is depressing as shit | 18:05 |
| nmz787 | eudoxia: why is it depressing? | 18:07 |
| eudoxia | various sorts of dead people | 18:12 |
| eudoxia | some of them interesting dead people, like Jerry Leaf | 18:12 |
| eudoxia | and Curtis Henderson | 18:13 |
| eudoxia | man fuck you Ben Best and your patient experimentation | 18:13 |
| @kanzure | https://www.noisebridge.net/wiki/Worldwide_Aaron_Swartz_Memorial_Hackathons | 18:15 |
| nmz787 | paperbot: http://www.sciencedirect.com/science/article/pii/S016777991100179X | 18:23 |
| paperbot | no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Error%20correction%20in%20gene%20synthesis%20technology.pdf | 18:23 |
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| * eudoxia sleeps | 18:49 | |
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| nmz787 | kanzure: do you know who ted myatt is? | 18:52 |
| nmz787 | oh, he's one of the diybio safety officers | 18:53 |
| nmz787 | he's trying to add me on linkedin | 18:54 |
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| nmz787 | kanzure: ever hear of iPython? | 22:22 |
| @kanzure | i use it all the time | 22:22 |
| nmz787 | oh really? | 22:22 |
| nmz787 | it looks a lot like matlab | 22:22 |
| @kanzure | i currently have 34 instances of ipython running | 22:22 |
| nmz787 | damn dude, share the love | 22:22 |
| nmz787 | how don't you spam about this? | 22:23 |
| nmz787 | :) | 22:23 |
| rigel | there was another python shell that i messed with a little bit that was great | 22:23 |
| rigel | i dont recall the name of it though | 22:23 |
| @kanzure | before ipython i was trying out bpython | 22:23 |
| @kanzure | but bpython has a bunch of minor bugs that accumulate into a giant disaster | 22:24 |
| rigel | i still need to work out the details of using virtualenv | 22:24 |
| rigel | that was probably it | 22:24 |
| rigel | i didnt mess with it enough to see the bugs | 22:24 |
| @kanzure | i use virtualenv-burrito to setup virtualenv on my machines | 22:24 |
| nmz787 | kanzure: have you used the webnotebook? | 22:24 |
| rigel | though iirc there was something odd like no scrollback or something | 22:24 |
| @kanzure | nmz787: nope. | 22:24 |
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| @kanzure | rigel: curl -s https://raw.github.com/brainsik/virtualenv-burrito/master/virtualenv-burrito.sh | bash | 22:25 |
| @kanzure | next: echo "source ~/.venvburrito/startup.sh" >> ~/.bashrc | 22:25 |
| rigel | meh | 22:25 |
| @kanzure | then you have mkvirtualenv and friends. | 22:26 |
| rigel | i do not need to mess with programming right now | 22:26 |
| rigel | i need to avoid failing my classes | 22:26 |
| rigel | and then i need to avoid failing my board exams | 22:26 |
| rigel | though i am hearing the call of programming and technical exploration more and more, in part simply because i am not constantly being evaluated on it and told "you suck pretty bad" | 22:27 |
| nmz787 | yeah i'm writing some openSpectrometer code now in python | 22:28 |
| rigel | i have been at least 1 SD, usually 1.7, sometimes as much as 3, below the mean. on every test so far for the last year and a half. | 22:28 |
| yashgaroth | are you pounding adderall | 22:28 |
| rigel | i wish i had access to adderall | 22:28 |
| @kanzure | you're in med school.. it would be hard to *not* run into adderall | 22:29 |
| yashgaroth | how do you survive in med school without addies | 22:29 |
| nmz787 | yashgaroth: looks like by being below the mean | 22:29 |
| yashgaroth | ask literally any of your classmates, or bluff a doctor | 22:29 |
| nmz787 | NPR was talking about Oprah's lance armstrong interview | 22:30 |
| nmz787 | and how he doped in every tour de france | 22:30 |
| nmz787 | and basically, yeah it's not a level playing field anymore for non-doped | 22:30 |
| nmz787 | if doping is taking place | 22:30 |
| nmz787 | which it obv is | 22:30 |
| @kanzure | when i was first getting interested in medicine, i thought this guy was the coolest dude ever for doing this: | 22:30 |
| @kanzure | http://www.pathguy.com/meltdown.txt | 22:30 |
| @kanzure | http://www.pathguy.com/boildown.txt | 22:31 |
| @kanzure | nmz787: lance should use his enormous fortune to convince people that doping isn't evil | 22:31 |
| @kanzure | nmz787: also they should keep the standings for the competitors because they were all on drugs anyway, so it's not like anything would have been different. | 22:32 |
| nmz787 | i dont know any more than i've said | 22:32 |
| rigel | i have sort of suggested to my pcp that maybe i could use some adderall | 22:37 |
| rigel | but they deflected | 22:37 |
| rigel | and honestly, i dont know that it would help | 22:37 |
| @kanzure | when you try to get adderall, never mention it by name | 22:38 |
| rigel | i get so fucking angry at how worthless this kind of teaching is | 22:38 |
| rigel | if i were hopped up on amphetamines i might stab someone | 22:38 |
| @kanzure | that's not how amphetamines work | 22:38 |
| rigel | oh, trust me i know how this shit works | 22:38 |
| rigel | "i cant focus" | 22:38 |
| rigel | "i am so distractable" | 22:38 |
| @kanzure | "my job is suffering" | 22:38 |
| rigel | i know how amphetamines work | 22:40 |
| rigel | i know that i turn into a gigantic asshole once the plasma levels drop below a particular point | 22:40 |
| @kanzure | i wish there was more research into how amphetamines actually work on a circuit-wide level | 22:40 |
| yashgaroth | well at least try modafinil or something; I don't want to mention nootropics or else an hour-long discussion of stackz will appear | 22:40 |
| rigel | and i know that i have anger control issues | 22:40 |
| @kanzure | "it modifies dopamine levels!" is such utter bullshit | 22:40 |
| @kanzure | http://diyhpl.us/wiki/amphetamine | 22:41 |
| rigel | i messed with adrafinil, piracetam, hydergine, etc during undergrad | 22:41 |
| rigel | 10 years ago | 22:41 |
| rigel | it would be hard to say that any of them did much | 22:41 |
| rigel | i hear modafinil is supposed to be good, but its still hideously expensive innit | 22:42 |
| yashgaroth | oh yes it is, it's only for when I feel too guilty about being lazy on weekends | 22:42 |
| rigel | bah, antiaging-systems no longer carries modafinil | 22:43 |
| yashgaroth | mymodafinil.net | 22:43 |
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| yashgaroth | well if stims don't seem to work for you, it's worth a shot to try cramming on opiates | 22:44 |
| rigel | still pretty fucking expensive | 22:45 |
| rigel | but it used to be like 2-3x what this site sells it for | 22:45 |
| rigel | maybe a scrip will be cheaper | 22:45 |
| yashgaroth | sure but once you're an MD you'll be making $texas | 22:45 |
| rigel | right, with $400k in loans to pay back | 22:45 |
| yashgaroth | sure, just do plastic surgery for a year | 22:46 |
| rigel | "just do plastic surgery" he/she says | 22:46 |
| yashgaroth | he, and yes I know | 22:46 |
| @kanzure | indeed, those "stem cell face lifts" are apparently hot.. :/ | 22:46 |
| rigel | because you certainly dont need to be certified, and do a residency in it, in order to do plastic surgery | 22:46 |
| @kanzure | i guarantee you that nobody did a residency in stem cell face lifting | 22:46 |
| yashgaroth | I severely doubt they even did med school for that matter | 22:47 |
| @kanzure | hi dr. nick | 22:47 |
| yashgaroth | ok well how about becoming a mob doctor? that's a thing | 22:47 |
| rigel | i dont think thats particularly well paid | 22:47 |
| yashgaroth | all the cocaine you want | 22:48 |
| rigel | i think thats something you do because you owe the shark about 80 large | 22:48 |
| nmz787 | kanzure: hell everybody | 22:49 |
| nmz787 | holle* | 22:49 |
| nmz787 | hello* | 22:49 |
| yashgaroth | hi* | 22:49 |
| nmz787 | yashgaroth: how did you get modafinil? | 22:49 |
| yashgaroth | mymodafinil.net, back when they were .com | 22:49 |
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| yashgaroth | premium quality indian generic foil sheets | 22:50 |
| brownies | you ordered from there? | 22:50 |
| yashgaroth | way back when, yeah | 22:50 |
| brownies | customs was cool with it? | 22:50 |
| yashgaroth | held up in customs for 10 days or something, but I guess so | 22:50 |
| yashgaroth | I think nowadays they're flagging it though, so good luck | 22:50 |
| brownies | i have no desire to engage in anything nearly that shady | 22:51 |
| brownies | i have just seen them hawking their wares on reddit, so i was curious | 22:51 |
| nmz787 | how way is way back? | 22:51 |
| yashgaroth | almost a year ago I think | 22:52 |
| rigel | oy | 22:53 |
| nmz787 | whats the armo* version? | 22:53 |
| rigel | someone i knew in undergrad used to get a whole lot of valium and codein from an outfit in spain called "libertarian solutions" | 22:53 |
| yashgaroth | haha | 22:53 |
| brownies | nmz787: regular mo is a racemic mixture; armo is the purified | 22:53 |
| rigel | again, 10 years ago, statute of limitations, etc | 22:53 |
| @kanzure | rigel: that's an amazing outfit name | 22:54 |
| yashgaroth | there is always silkroad too | 22:54 |
| nmz787 | ahh | 22:54 |
| brownies | obviously that is the simplified explanation and i am not your doctor/lawyer/dentist/etc | 22:54 |
| @kanzure | "Mobular Solutions".. send cell phones through customs for mob bosses. | 22:54 |
| rigel | it was in keeping with their predilection for purchasing little quantities of every alphabet soup psychedelic/enpathogen to come down the pike | 22:54 |
| brownies | wikipedia has some nice explanations on this all ... though i wouldn't mind seeing some more studies on the psychopharmacology of such things | 22:54 |
| rigel | 2ct7, 4-AcO-DiPT, MBDB, etc | 22:54 |
| nmz787 | yeah i would like to see some neural reprogramming studies undertaken with psychedelics/empathogens in rats or mice | 22:58 |
| @kanzure | huh? there are tons of studies with psychadelics+mice.. | 22:58 |
| nmz787 | i guess there are the psilocin experiments in humans happening now, NYU I think | 22:58 |
| rigel | i signed up for the hopkins studies | 22:58 |
| rigel | they were trying to sign people up for that stuff for smoking cessation | 22:59 |
| rigel | it was crazy | 22:59 |
| nmz787 | there was a conference last summer on the subject near philadelphia | 22:59 |
| rigel | i just didnt have enough spare time to go in for the sessions and debriefing etc | 22:59 |
| rigel | it would have been hella cool | 22:59 |
| rigel | but just too much time investment | 22:59 |
| nmz787 | i hear tijuana has ibogaine clinics | 23:00 |
| rigel | because it was always on weekdays | 23:00 |
| brownies | rigel: i wish they would publish their exact experimental protocol for those studies | 23:00 |
| augur_ | there are tones of studies with psychedelics and people | 23:01 |
| augur_ | oh neural reprogramming | 23:01 |
| augur_ | depends on what you mean | 23:02 |
| brownies | really? other than the Hopkins ones, i'm not aware of anything interesting/recent | 23:02 |
| augur_ | if you mean some NLP hogwash, hah. | 23:02 |
| nmz787 | augur_: yeah pretty broad term | 23:02 |
| brownies | i don't know what "neural reprogramming" is... i'd just be interested to see more study done on it. | 23:02 |
| rigel | if a site is advertising on reddit then it's probably going to be throwing money down the toilet | 23:04 |
| rigel | the fucking president gets on reddit! | 23:04 |
| @kanzure | http://www.hoektronics.com/2013/01/05/meet-a-shenzhen-maker-mr-chen/ | 23:06 |
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| @kanzure | http://bbs.eetop.cn/ | 23:14 |
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| nmz787 | damn, is it worth learning chinese at this age? | 23:22 |
| nmz787 | would that work well? | 23:22 |
| @kanzure | nmz787: http://pinyin.info/readings/texts/moser.html | 23:25 |
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| brownies | nmz787: ni hao, bro. | 23:49 |
| @kanzure | http://www.szdiy.org/ | 23:53 |
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