2013-05-09.log

--- Log opened Thu May 09 00:00:21 2013
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ParahSailinpaperbot: http://www.nature.com/nature/journal/v485/n7396/full/485041e.html10:01
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/Editorial%20note.pdf10:01
ParahSailinpaperbot: http://www.nature.com/nature/journal/v483/n7391/full/483531a.html10:02
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/Drug%20development%3A%20Raise%20standards%20for%20preclinical%20cancer%20research.pdf10:02
@kanzure.title http://www.nature.com/nature/journal/v485/n7396/full/485041e.html10:03
yoleauxEditorial note : Nature : Nature Publishing Group10:03
@kanzurebah10:03
ParahSailin'Fifty-three papers were deemed ‘landmark’ studies (see ‘Reproducibility of research findings’). It was acknowledged from the outset that some of the data might not hold up, because papers were deliberately selected that described something completely new, such as fresh approaches to targeting cancers or alternative clinical uses for existing therapeutics. Nevertheless, scientific findings were confirmed in onl10:05
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@kanzurecutoff at "findings were confirmed in onl"10:29
ParahSailinwow, i thought irssi wasnt completely retarded10:32
ParahSailinonly 6 (11%) cases.'10:32
@kanzureyou have to install an irssi script to fix that situation10:32
@kanzurejust some more people worth stalking:10:51
@kanzurehttp://www.fastcoexist.com/1682017/this-years-thiel-fellows-include-a-fashion-designer-a-poet-and-a-harvard-dropout10:51
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ParahSailin.title http://www.zdnet.com/microsofts-most-profitable-mobile-operating-system-android-7000015094/11:31
yoleauxMicrosoft's most profitable mobile operating system: Android | ZDNet11:31
ParahSailinanyone have interest in a data dump of 300k name, address, phone number, and credit score?11:46
ParahSailinits data that equifax sold some company11:46
@kanzureanother secret group (ugh, why can't they just stay in one place) https://groups.google.com/group/diybio-idealab11:51
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@kanzurehmm http://fixthedmca.org/unlocking-technology-act.html " It amends Section 1201 to make it clear that it is completely legal to "circumvent" if there is no copyright infringement.  It legalizes tools and services that enable circumvention as long as they are intended for non-infringing uses. It changes Copyright Law to specify that unlocking cell phones is not copyright infringement."12:11
@kanzurehttps://dl.dropboxusercontent.com/u/3155588/Unlocking%20Technology%20Act.pdf12:12
@kanzuresaurik's logo is on that page, heh12:13
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eudoxiahttp://www.forbes.com/sites/andygreenberg/2013/05/09/state-department-demands-takedown-of-3d-printable-gun-for-possible-export-control-violation/13:25
eudoxia.title13:25
yoleauxState Department Demands Takedown Of 3D-Printable Gun Files For Possible Export Control Violations - Forbes13:26
eudoxia"The government says it wants to review the files for compliance with arms export control laws known as the International Traffic in Arms Regulations, or ITAR."13:26
eudoxiai so fucking called it13:26
eudoxiai wish i had a twitter account to dump my irrelevant thoughts into so i could prove it tho13:26
@kanzurewhat's important about "calling it" in this case?13:27
eudoxiahttp://defcad.org/13:27
eudoxia.title13:27
yoleauxDEFCAD13:27
@kanzureyes we know the title of that page is DEFCAD13:27
eudoxiahuh how weird it gave me a 50313:27
@kanzurebut what does it matter? there's a backup of their zip file floating around the net. what else did they do?13:27
ParahSailinthey got an ffl i think13:28
eudoxiawell yeah there's still the torrents on TPB and duce's github repo13:28
eudoxiahttps://github.com/maduce/defcad-repo13:28
eudoxiabut still it's a pretty big deal that they are being taken down and it's not april's fools this time13:29
ParahSailinis defcad different from defense distributed?13:30
eudoxiadefcad is defdist's repo and soon to be 3dp search engine13:31
@kanzure"soon to be" "3dp search engine" ugh13:32
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eudoxiaoh kanz it's just a search engine it's not like they are promising eternal youth13:32
eudoxiahow much could they fuck it up?13:33
@kanzurei don't understand why they need to make a search engine13:33
@kanzuredo you really think that a bunch of people that put .zip files into a git repository have the technical chops to make a legitimate search engine? they should just use lucene or solr or something.13:34
klafkakanzure: has anyone made a generative art program for 3d printers ?13:34
@kanzureprobably. i wrote one at some point.13:34
klafkaoh they're rolling their own search engine, lol13:34
klafkai'm thinking of making one13:34
klafkadid you use people as the fitness function?13:34
@kanzuremine was based on some basic shapes from pythonocc, i think. and skdb. part interfaces connecting. something.13:34
@kanzurei had no fitness function, i just wanted not-completely-intersecting shapes.13:35
eudoxiamaybe they will use that, i don't know what they're up to13:35
@kanzurehttp://heybryan.org/shots/2008-11-02_supermetal_2.png13:35
klafkaah cool13:35
eudoxiaalthought yeah people who do 'git add ., git commit -a -m "megapack version X",git push github master' might fall short of expectations13:35
@kanzures/,/;/ maybe13:37
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@kanzurerigel: welcome back14:18
rigelthx14:19
rigelnot joining was a simple oversight14:19
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ParahSailinpaperbot, next time they make me write their paper i will put an easter egg just in case they do not put my name on as an author http://www.sciencedirect.com/science/article/pii/S004268221300199214:47
ParahSailinpaperbot, http://www.sciencedirect.com/science/article/pii/S004268221300199214:48
paperbotno translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Small%20RNA%20populations%20for%20two%20unrelated%20viruses%20exhibit%20different%20biases%20in%20strand%20polarity%20and%20proximity%20to%20terminal%20sequences%20in%20the%20insect%20host%20.pdf14:48
@kanzureyeah, i am a little upset about two cases of that happening to me as well.14:49
@kanzureit would be interesting to measure how often authors are not included14:49
@kanzureyou could even do verification like "yep, that person was definitely employed in that lab at the time, and social networks seem to confirm he's affiliated with some of those people, and these other pile of metrics suggest a high probability that this guy was just screwed"14:50
ParahSailini need a standard stegano watermark for all images produced by my user on matplotlib14:52
ParahSailinjust in case clients are ever lazy enough to use images i give them as-is14:53
@kanzurehah14:53
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@kanzuresigh http://www.slashgear.com/biohacking-kickstarter-project-promises-glowing-plant-seeds-09281173/16:51
ParahSail1nfuck, 284k16:53
@kanzureyep :/16:53
ParahSail1nkickstarter chicanery still below your price point?16:54
@kanzurehm?16:54
@kanzurei still haven't seen anyone actually demonstrate an understanding of how these are different types of "glowing"16:55
@kanzure"who cares! it glows! don't hate us. we promise it is glowing." yeah but luminescence is not the same as ultraviolet response is not the same as.. etc.16:56
ParahSail1nfor 284k theyll have something glowing16:56
@kanzuresure.16:57
ParahSail1nmight have to use nightvision goggles, but it will luminesce16:57
@kanzuredoes the kickstarter page even say which type?16:57
ParahSail1nlux operon...16:57
@kanzureoh look, they even list out their names so we can actually hate people16:58
@kanzureomri amirav-drory (who we can also hate for his bullshit marketing about his "open" "genome compiler"), antony evans, kyle taylor, patrik d'haeseleer, darius lau, rick symonds, cameron clarke, anat reichman, andreas stuermer, ariel mioduser, patrick buckley16:58
ParahSail1nlets do a thc arabidopsis indiegogo16:59
ParahSail1nim sure there are lots of potheads in the world16:59
@kanzurei thought there was a missing piece of the pathway16:59
ParahSail1nkanzure, shhh16:59
@kanzurealso i hear grad students proposing that all the time, there was some missing piece until recently..16:59
@kanzureby recently i mean maybe 2009 or 201016:59
@kanzurei don't see anything about any particular operon on this page or their blog17:00
ParahSail1nwell the species was sequenced last year so the indiegogo would at least be plausible enough to stand up to basic retard due diligence17:00
@kanzureoh they are doing luciferin/luciferase?17:00
@kanzurehow exactly does a plant have enough metabolic energy for that one17:01
ParahSail1nhttp://boingboing.net/2013/04/24/synthetic-biology-kickstarter.html17:02
ParahSail1nsorry dont click17:02
ParahSail1ngoogle results said lux operon but that was only in comments17:02
@kanzureyeah but they seem to be working off of someone's igem project, http://glowingplant.com/post/49334047062/how-bright-can-we-make-plants-glow17:02
@kanzurehttp://2010.igem.org/Team:Cambridge17:03
@kanzure"The $65k initial goal will allow us to replicate the work of the SUNY researchers, and add a luciferin recycling gene."17:03
@kanzureoh god i hate this guy "But we will go one step further than this and will be sharing online all of the work we are doing - the ups as well as the downs.  In fact our DNA designs are already publicly available and if you download Genome Compiler’s software you can view them. W"17:04
@kanzuresigh. genome compiler is not a compiler. it's the name of a company. and the company has never built a compiler.17:04
@kanzurewell, at least it doesn't require ultraviolet spectrum everywhere.17:05
ParahSail1nglowing rose plant... is rose even sequenced?17:07
ParahSail1n"For a prototype we inserted GFP, a flouresent protein, into the plant."17:08
@kanzureoh :(17:09
browniesgetting ever-closer to a glowing cat!17:39
brownies.meow17:39
yoleauxhttp://moar.edgecats.net/cats/anigif_enhanced-buzz-10181-1323295701-15.gif17:39
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ParahSail1napparently musk had to ask customers to pay early payments on leases to get a 1Q positive cash flow18:17
klafkaoh?18:18
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@kanzureyashgaroth: supp18:28
@kanzurewe're bitching about luciferase today18:28
yashgarothI'm just catching up on the logs18:28
yashgarotheven if they get the luciferin recycling enzyme won't people still need to buy luciferin to feed their plant18:31
ParahSail1npretty sure lux does not require luciferin18:31
@kanzurei'm not really sure how much energy the enzyme takes, but my original guess was "a shitload"18:32
yashgarothoh they're using lux?18:32
ParahSail1nunless theyre total charlatan's i'd say theyre using lux18:32
yashgarothfair point18:33
@kanzurei'm confused; aren't they explicitly saying they are doing http://2010.igem.org/Team:Cambridge18:33
ParahSail1ni have a feeling that theyre going to be using classical cloning methods to assemble their construct18:35
@kanzurealso, fireflies aren't what i remember them to be http://2010.igem.org/wiki/images/thumb/f/f2/Firefly.jpg/300px-Firefly.jpg18:35
@kanzurethis looks closer to what i remember catching http://2010.igem.org/wiki/images/thumb/3/32/Cambridge-Firefly_side.jpg/250px-Cambridge-Firefly_side.jpg18:35
yashgarothyeah no I think they are going for luciferase18:36
@kanzureisn't plant metabolism supposed to be slow and plodding?18:36
@kanzureand low energy18:36
Juuli'm gonna stick some flowers in some fluorescent water18:54
Juulit'll probably get better results18:54
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@kanzureJuul: lemme know how that goes.19:25
Juulk19:25
@kanzurescience!19:25
Juulhttp://images.cryhavok.org/d/11335-1/Dresden+Codak+-+I+Will+Do+Science.jpg19:27
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@kanzurethat is approximately what i had in mind, yes19:30
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abetuskyou think they'll be able to achieve their goal of a glowing plant?20:06
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@kanzureeven if they are, they are terrible people for not being specific, and terrible people for supporting genome compiler, and a few other reasons :|20:08
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abetuskThey've opened everything, or said they'll open everything.  You're concerned about the lack of detail from the kickstarter page?20:11
ParahSail1ntheyre not supporting genome compiler, they are genome compiler20:13
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@kanzureoh you know, i bet it was genome compiler that dumped $10k into the project, not cambrian genomics like nmz787 theorized20:20
ParahSail1nisnt genome compiler, cambrian genomics, and the names on the kickstarter all the same?20:20
@kanzurecambrian genomics has no prior history of doing silly marketing stunts20:21
@kanzureor lying20:21
ParahSail1nprior history in how long?20:22
@kanzureso i would be more willing to attribute the marketing stunt to genome compiler. who else would dump $10k so early into that kickstarter? some random user within the first 100 users that loaded the page decided to donate $10k? yeah right..20:22
@kanzurewell, i've known cambrian genomics since it started i guess20:22
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ParahSail1nah, its a bain co consultant scumbag putting this on20:38
ParahSail1nyeah, doesnt surprise me at all20:38
@kanzurei'm not familiar with that company. are they the mckinsey of.. whatever?20:39
@kanzureoh in fact they are. okay. cool.20:39
@kanzurebigger than deloitte too.20:39
ParahSail1ntheyre sort of like mckinsey, except mitt romney20:39
@kanzureby "cool" i mean "cool that i predicted as much" not "that's a cool company" because it isn't.20:40
ParahSail1nnot much of a stretch to from consulting to other scams20:44
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@kanzureso, shodan is pretty useful.. http://www.shodanhq.com21:28
@kanzureit aggregates port scans for easy searching21:28
@kanzuredefcad seems to have about 1k seeders at the moment, https://thepiratebay.sx/search/defcad/0/99/021:29
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ParahSail1nhad like 5k seeders when i dl'd21:42
@kanzurehahah "ATTENTION #defcad: WE have MOVED the IRC to irc.oftc.net #defcad"21:43
ParahSail1ner why not freenode21:43
@kanzurefreenode does not allow tor users21:44
ParahSail1nah21:44
@kanzureoh man #defcad is super low quality. what is this shit..21:48
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@kanzure"The kickstarter funding crossed the $300k mark just now. "22:17
@kanzurebleh22:17
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ParahSail1nyou sure you dont want to put on a scammy kickstarter?22:21
@kanzurefor the right idea, i would be willing to pay $2-$5k for a stellar video to be created22:22
@kanzurekickstarter is mostly about how great you can get that video22:23
ParahSail1nthere are consultants who specialize in kickstarters22:23
ParahSail1ni know, because the cfo of eg was talking about hiring them for the "great canine project" one22:23
ParahSail1nmr bain consultant over there was surely savvy to that22:24
ParahSail1nif the vc-stan set can value a company that sells 20,000 cars a year at 1/10 of ford, then anything is possible22:25
@kanzurehaha consultants.. that's a lie.22:26
@kanzurei mean, you just have to be very anal about how you setup your kickstarter project. if you want to pay someone for that, fine. but unless they are guaranteeing you $x amount of money raised, they are full of it.22:26
klafka_i was thinking of doing a kickstarter22:30
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ParahSail1nwell thats the first step22:33
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juri_I've been in two kickstarter videos already. i find its valuable, for getting the team together in meatspace, that's about it.22:38
@kanzurebeing in the videos doesn't matter as much; it just has to be flashy and good production values22:38
@kanzurenmz787 kinda screwed up on this front, he thought it was based on merit22:38
browniesit is a meritocracy. it's just that the measure of merit is how good of a video you make ;)22:41
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@kanzurewtf there have been 4 people who donated $10k to their glowstarter22:46
@kanzurecambrian genomics is claiming $0.0001/bp by 2015.22:48
ParahSail1nlolk22:53
@kanzurei wonder if we could get people to put money behind synthesis predictions as a way to fund better synthesis or something22:57
ParahSail1nmaybe bryan caplan would make such a bet22:59
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ParahSail1noh wait, they have bitcoin prediction markets now23:09
klafka_start a btc derivative market23:10
klafka_to fund your project23:10
ParahSail1ni dont have an identity to burn23:10
@kanzurei can give you satoshi's identity23:12
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--- Log closed Fri May 10 00:00:22 2013

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