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bertm | paperbot http://dx.doi.org/10.1016/0021-9517(67)90181-9 | 03:56 |
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paperbot | http://diyhpl.us/~bryan/papers2/paperbot/5e64ec53aed2dd9f997bae4163bc3849.txt | 03:56 |
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Lemminkainen | paperbot http://www.nature.com/nbt/journal/v31/n11/full/nbt.2746.html | 04:43 |
paperbot | http://libgen.org/scimag/get.php?doi=10.1038%2Fnbt.2746 | 04:43 |
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drewbug | paperbot, http://www.ncbi.nlm.nih.gov/pubmed/20087132 | 11:26 |
paperbot | http://libgen.org/scimag/get.php?doi=10.1227%2F01.NEU.0000360379.95800.2F | 11:26 |
drewbug | PAPERBOT, HTTP://WWW.NCBI.NLM.NIH.GOV/pubmed/20087132 | 11:27 |
kanzure_ | intense. | 11:27 |
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drewbug | Gotta be stern. | 11:28 |
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delinquentme | paperbot, http://onlinelibrary.wiley.com/doi/10.1002/adma.200803702/abstract | 14:34 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/ddc1fc7e6b7fb240aad93b8af545233b.txt | 14:35 |
delinquentme | paperbot, http://onlinelibrary.wiley.com/doi/10.1002/adma.200803702/pdf | 14:35 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/9215a4849c511e4540f053754368b5bf.txt | 14:35 |
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delinquentme | Do we have any people who work in pharma computational chemistry? | 14:46 |
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nmz787 | delinquentme: http://diyhpl.us/~nmz787/pdf/Direct-Write_Assembly_of_3D_Hydrogel_Scaffolds_for_Guided_Cell_Growth.pdf | 15:12 |
delinquentme | nmz787, you applied to schrodinger right? | 15:13 |
delinquentme | have you talked with any of their people? | 15:13 |
nmz787 | yes | 15:13 |
nmz787 | no | 15:13 |
nmz787 | they dealt only in email | 15:13 |
nmz787 | possibly because i dont have a degree | 15:13 |
nmz787 | not sure what info i gave them | 15:14 |
delinquentme | Oh by talk I mean any kind of interesting communication | 15:14 |
nmz787 | nope | 15:14 |
delinquentme | ah. LAMESAUCES | 15:14 |
nmz787 | they have a local office downtown, so i was a little disappointed | 15:14 |
kanzure | i received email from jonathan.draxton@schrodinger.com in june when they were looking for a front-end developer | 15:15 |
kanzure | "My name is Jonathan Draxton, and I'm an associate at Schrödinger, an international life science research and development company funded in part by Bill Gates. Looking at your programming skill set, I thought you might be interested to know that Schrödinger is currently building something that's going to revolutionize the drug discovery process. To do this, our engineers need more front-end experts who are proficient in languages like ... | 15:15 |
kanzure | ... JavaScript, Python, and PHP. What do you think? Does this sound of interest to you?" | 15:15 |
juri_ | pfft. | 15:15 |
kanzure | no kidding | 15:16 |
kanzure | "Here's a short video of Scott Becker, our VP of Enterprise Products, talking a little bit about what we're doing: http://vimeo.com/49879101 " | 15:16 |
juri_ | "i'm using large names to try and drag in developers who have only basic proficiencies. feel like being abused, and blamed when everything goes wrong?" | 15:16 |
kanzure | to be honest, based on the going rates, pay me $300k/year and blame it on me? i don't care, give me money | 15:17 |
gradstudentbot | I have to order new primers. | 15:17 |
delinquentme | "going rates" ? | 15:17 |
kanzure | you can blame anything on me | 15:17 |
kanzure | my point is that for a competent front-end dev you're looking at a substantial pile of money | 15:17 |
juri_ | "oh, and when we blame it on you, we will do far more damage in shaming your industry than you can do good with the money." | 15:18 |
kanzure | that's not what happens though | 15:18 |
kanzure | i mean, those are empty threats | 15:18 |
juri_ | "humanityplus is doomed, because php programmers suck. obviously." | 15:18 |
juri_ | -- Bill gates | 15:18 |
kanzure | there might be more truth to that fakequote than you might think | 15:18 |
chris_99 | anyone 'ere, played with ultrasound out of interest, specifically calculating speed of sound? | 15:19 |
delinquentme | its not a fake quote anymore! Its documented on the internet! | 15:19 |
kanzure | (based on my experience of code reviewing php from humanityplus) | 15:19 |
juri_ | kanzure: me and my partner maintain a rapid application development framework written in PHP. feel free to use, or review it. | 15:19 |
delinquentme | kanzure, nmz787 my deepest hope for this email is that they'd give me some insights as to how their internal R&D is updating their simulation models | 15:20 |
delinquentme | Also I had this idea to sell microfluidic chips with skin cultures to the cosmetics industry | 15:20 |
delinquentme | holy fuck. | 15:21 |
delinquentme | I just had an idea. | 15:21 |
delinquentme | @_@!!!!!!!!!!!!! | 15:21 |
kanzure | ugh | 15:21 |
nmz787 | gnarly dude | 15:21 |
nmz787 | cowabunga | 15:21 |
kanzure | juri_: have you used flask, sinatra or express? | 15:22 |
delinquentme | kanzure, nmz787 thoughts on the email to schrodinger? Im in the process of looking up the specialities / dissertations of their scientific team | 15:23 |
delinquentme | also is the biochip for skin cells / cosmetics to replace animal testing a crap idea? | 15:23 |
juri_ | kanzure: i haven't heard of either of the three. | 15:23 |
kanzure | juri_: have you only used "rapid application development frameworks" in php? | 15:23 |
juri_ | kanzure: that would be a correct asertion. | 15:24 |
juri_ | in other languages, i haven't needed much framework. i tend toward the bare metal stuffs. | 15:24 |
delinquentme | PS kanzure the music in this schrodinger video is awful strummy hippy love shit | 15:24 |
delinquentme | HOW ARE WE SUPPOSED TO FIX ALL THE THINGS... if we dont have glitchmob esqe hot music to hype our progress =[[[ | 15:25 |
kanzure | juri_: how do you know you're making sane or rational decisions without a breadth of experience? i highly recommend trying django, rails, express, flask, bottle, pyramid, larvitar | 15:25 |
juri_ | delinquentme: i would say your biochip for testing makes long term species sense... the real question you should be asking yourself is whether moore's law is going to make the technology to make better versions of those than real live animals any time soon. | 15:26 |
kanzure | and maybe some spring shit in there just so that you cover some oldstuff for the hell of it | 15:26 |
delinquentme | juri_, you're asking if we're going to have the simulation models for these down sooner than just sticking those cells on chips and getting them to work? | 15:27 |
delinquentme | kanzure, I want to scream at you. Needs yewar guidance | 15:27 |
delinquentme | YUNO play in sandbox ? | 15:27 |
juri_ | kanzure: my php experiences have usually been limited to either large projects with 5 competing frameworks poorly integrated, or tiny php apps. i'm not sure i'm in much of a 'rational decision' state, your observation makes some sense. i don't see myself getting to that state, because i've got my nose way too close to the grindstone. | 15:28 |
* delinquentme pees in sandbox | 15:28 | |
kanzure | you want my guidance writing an email about what exactly | 15:28 |
delinquentme | I want to know what things I should ask to get the answers I'm looking for. I want to know if they've got some kind of automated bioreactor automation in house to update these models | 15:29 |
gradstudentbot | Yeah, I'm just looking for a journal that will take that paper. | 15:29 |
juri_ | delinquentme: no, i'm actually asking if (for a varying definition of better) there will come a tipping point where it makes more sense to use chips containing cells, than animals. | 15:29 |
entelechios | dude | 15:29 |
entelechios | my kids play in there | 15:29 |
entelechios | what the fuck is wrong with you | 15:29 |
nmz787 | delinquentme: asking that sounds good | 15:30 |
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nmz787 | "do you check your models against in-vitro or in-vivo or in-situ (aka non in-silico)" | 15:30 |
kanzure | asking direct questions is not always the best way to get answers | 15:31 |
nmz787 | seems like they have to, or they mine literature like crazy | 15:31 |
nmz787 | otherwise they'd be pulling numbers outta their ass | 15:31 |
delinquentme | nmz787, well they have internal R&D as well as guys who are explicitly R&D | 15:31 |
kanzure | often there is information that is considered off-limits until you divulge something else | 15:31 |
delinquentme | but that doesn't tell me how much automation is in that process | 15:31 |
delinquentme | true | 15:31 |
nmz787 | i'm not so good at social engineering i guess :P | 15:32 |
kanzure | "i stalked you at the last 10 parties we mutually went to, therefore we are now friends" | 15:32 |
kanzure | "what no way man, you don't remember me? shit, well akram remembers me.. ah akram is working for you?" | 15:32 |
kanzure | and then i realize i'm talking to the wrong person | 15:32 |
kanzure | brownies pulled a trick on me a while back | 15:33 |
Lemminkainen | social engineering? | 15:33 |
kanzure | the company knew him as paul, but his name wasn't paul, so they asked me how i knew paul | 15:33 |
Lemminkainen | just be friendly | 15:33 |
kanzure | i am not talking about social engineering | 15:33 |
Lemminkainen | social engineering is for spergtards who are trying to grow out of their neckbeard phase | 15:33 |
nmz787 | social stumbling | 15:33 |
Lemminkainen | kanzure isn't nmz787 was | 15:33 |
kanzure | being friendly is necessary but not sufficient- this is why wordsmithing is useful | 15:33 |
delinquentme | Lemminkainen, I've not trimmed in a few days. | 15:34 |
nmz787 | months of growth for me | 15:34 |
delinquentme | other than PLA ... are there other known bio-compatible 3dprinter filaments? | 15:35 |
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delinquentme | from the (little) research I've done ... the number of bio-compatible photopolymers is WAY more | 15:35 |
entelechios | be gregarious | 15:36 |
nmz787 | sucrose | 15:36 |
nmz787 | sugar glass | 15:37 |
nmz787 | highly biodegradable | 15:37 |
juri_ | i wonder how i'd print that. :/ | 15:39 |
nmz787 | jmil posted a howto | 15:39 |
Lemminkainen | btw, I submit that there is a respectful difference between a sperglord and a spergtard | 15:39 |
nmz787 | that's too much deutcsch for me to comprehend | 15:39 |
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Lemminkainen | wir können etwas genauer sprechen, wenn du das willst | 15:40 |
nmz787 | du, du hast, du has mich | 15:40 |
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nmz787 | ein zwei dright veir have another glass of bier! | 15:41 |
Lemminkainen | ich haße dich nicht | 15:41 |
delinquentme | Im freaking out in my head right now | 15:42 |
delinquentme | caffeine oh how I missed yew | 15:42 |
juri_ | oh god, where is my coffee cup! | 15:42 |
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nmz787 | i got an espresso machine at goodwill a few months ago | 15:43 |
nmz787 | it is being loved well | 15:43 |
nmz787 | along with raw grass-fed milk foamed | 15:43 |
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Lemminkainen | we need to make algae lactate interesting casein micellar complexes so that we can make milk more interesting | 15:53 |
Lemminkainen | add in some BCAAs and omega-3 PUFAs and get rid of that pesky lactose | 15:54 |
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bkero | Where did poppingtonic go? :( | 17:46 |
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FourFire | " | 18:20 |
FourFire | <juri_> "humanityplus is doomed, because php programmers suck. obviously."" I thought it was just php which sucked | 18:20 |
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jrayhawk | humanityplus is the next facebook, because php | 18:40 |
kanzure | your powers of reasoning fascinate me | 18:41 |
kanzure | mostly they confuse me | 18:41 |
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juri_ | reasoning is completely optional. | 18:55 |
delinquentme | http://www.sciencedaily.com/releases/2012/10/121002150031.htm | 18:58 |
delinquentme | bullshit? | 18:58 |
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Dantespeaks | hahaha foools | 19:12 |
Dantespeaks | oh sorry wroong chanell | 19:13 |
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