2013-12-30.log

--- Log opened Mon Dec 30 00:00:08 2013
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bertmpaperbot http://dx.doi.org/10.1016/0021-9517(67)90181-903:56
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/5e64ec53aed2dd9f997bae4163bc3849.txt03:56
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Lemminkainenpaperbot http://www.nature.com/nbt/journal/v31/n11/full/nbt.2746.html04:43
paperbothttp://libgen.org/scimag/get.php?doi=10.1038%2Fnbt.274604:43
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drewbugpaperbot, http://www.ncbi.nlm.nih.gov/pubmed/2008713211:26
paperbothttp://libgen.org/scimag/get.php?doi=10.1227%2F01.NEU.0000360379.95800.2F11:26
drewbugPAPERBOT, HTTP://WWW.NCBI.NLM.NIH.GOV/pubmed/2008713211:27
kanzure_intense.11:27
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drewbugGotta be stern.11:28
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delinquentmepaperbot, http://onlinelibrary.wiley.com/doi/10.1002/adma.200803702/abstract14:34
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/ddc1fc7e6b7fb240aad93b8af545233b.txt14:35
delinquentmepaperbot, http://onlinelibrary.wiley.com/doi/10.1002/adma.200803702/pdf14:35
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/9215a4849c511e4540f053754368b5bf.txt14:35
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delinquentmeDo we have any people who work in pharma computational chemistry?14:46
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nmz787delinquentme: http://diyhpl.us/~nmz787/pdf/Direct-Write_Assembly_of_3D_Hydrogel_Scaffolds_for_Guided_Cell_Growth.pdf15:12
delinquentmenmz787, you applied to schrodinger right?15:13
delinquentmehave you talked with any of their people?15:13
nmz787yes15:13
nmz787no15:13
nmz787they dealt only in email15:13
nmz787possibly because i dont have a degree15:13
nmz787not sure what info i gave them15:14
delinquentmeOh by talk I mean any kind of interesting communication15:14
nmz787nope15:14
delinquentmeah. LAMESAUCES15:14
nmz787they have a local office downtown, so i was a little disappointed15:14
kanzurei received email from jonathan.draxton@schrodinger.com in june when they were looking for a front-end developer15:15
kanzure"My name is Jonathan Draxton, and I'm an associate at Schrödinger, an international life science research and development company funded in part by Bill Gates. Looking at your programming skill set, I thought you might be interested to know that Schrödinger is currently building something that's going to revolutionize the drug discovery process. To do this, our engineers need more front-end experts who are proficient in languages like ...15:15
kanzure... JavaScript, Python, and PHP. What do you think? Does this sound of interest to you?"15:15
juri_pfft.15:15
kanzureno kidding15:16
kanzure"Here's a short video of Scott Becker, our VP of Enterprise Products, talking a little bit about what we're doing: http://vimeo.com/49879101 "15:16
juri_"i'm using large names to try and drag in developers who have only basic proficiencies. feel like being abused, and blamed when everything goes wrong?"15:16
kanzureto be honest, based on the going rates, pay me $300k/year and blame it on me? i don't care, give me money15:17
gradstudentbotI have to order new primers.15:17
delinquentme"going rates" ?15:17
kanzureyou can blame anything on me15:17
kanzuremy point is that for a competent front-end dev you're looking at a substantial pile of money15:17
juri_"oh, and when we blame it on you, we will do far more damage in shaming your industry than you can do good with the money."15:18
kanzurethat's not what happens though15:18
kanzurei mean, those are empty threats15:18
juri_"humanityplus is doomed, because php programmers suck. obviously."15:18
juri_-- Bill gates15:18
kanzurethere might be more truth to that fakequote than you might think15:18
chris_99anyone 'ere, played with ultrasound out of interest, specifically calculating speed of sound?15:19
delinquentmeits not a fake quote anymore! Its documented on the internet!15:19
kanzure(based on my experience of code reviewing php from humanityplus)15:19
juri_kanzure: me and my partner maintain a rapid application development framework written in PHP. feel free to use, or review it.15:19
delinquentmekanzure, nmz787 my deepest hope for this email is that they'd give me some insights as to how their internal R&D is updating their simulation models15:20
delinquentmeAlso I had this idea to sell microfluidic chips with skin cultures to the cosmetics industry15:20
delinquentmeholy fuck.15:21
delinquentmeI just had an idea.15:21
delinquentme@_@!!!!!!!!!!!!!15:21
kanzureugh15:21
nmz787gnarly dude15:21
nmz787cowabunga15:21
kanzurejuri_: have you used flask, sinatra or express?15:22
delinquentmekanzure, nmz787 thoughts on the email to schrodinger?  Im in the process of looking up the specialities / dissertations of their scientific team15:23
delinquentmealso is the biochip for skin cells / cosmetics to replace animal testing a crap idea?15:23
juri_kanzure: i haven't heard of either of the three.15:23
kanzurejuri_: have you only used "rapid application development frameworks" in php?15:23
juri_kanzure: that would be a correct asertion.15:24
juri_in other languages, i haven't needed much framework. i tend toward the bare metal stuffs.15:24
delinquentmePS kanzure the music in this schrodinger video is awful strummy hippy love shit15:24
delinquentmeHOW ARE WE SUPPOSED TO FIX ALL THE THINGS... if we dont have glitchmob esqe hot music to hype our progress =[[[15:25
kanzurejuri_: how do you know you're making sane or rational decisions without a breadth of experience? i highly recommend trying django, rails, express, flask, bottle, pyramid, larvitar15:25
juri_delinquentme: i would say your biochip for testing makes long term species sense... the real question you should be asking yourself is whether moore's law is going to make the technology to make better versions of those than real live animals any time soon.15:26
kanzureand maybe some spring shit in there just so that you cover some oldstuff for the hell of it15:26
delinquentmejuri_, you're asking if we're going to have the simulation models for these down sooner than just sticking those cells on chips and getting them to work?15:27
delinquentmekanzure, I want to scream at you. Needs yewar guidance15:27
delinquentmeYUNO play in sandbox ?15:27
juri_kanzure: my php experiences have usually been limited to either large projects with 5 competing frameworks poorly integrated, or tiny php apps. i'm not sure i'm in much of a 'rational decision' state, your observation makes some sense. i don't see myself getting to that state, because i've got my nose way too close to the grindstone.15:28
* delinquentme pees in sandbox15:28
kanzureyou want my guidance writing an email about what exactly15:28
delinquentmeI want to know what things I should ask to get the answers I'm looking for.  I want to know if they've got some kind of automated bioreactor automation in house to update these models15:29
gradstudentbotYeah, I'm just looking for a journal that will take that paper.15:29
juri_delinquentme: no, i'm actually asking if (for a varying definition of better) there will come a tipping point where it makes more sense to use chips containing cells, than animals.15:29
entelechiosdude15:29
entelechiosmy kids play in there15:29
entelechioswhat the fuck is wrong with you15:29
nmz787delinquentme: asking that sounds good15:30
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nmz787"do you check your models against in-vitro or in-vivo or in-situ (aka non in-silico)"15:30
kanzureasking direct questions is not always the best way to get answers15:31
nmz787seems like they have to, or they mine literature like crazy15:31
nmz787otherwise they'd be pulling numbers outta their ass15:31
delinquentmenmz787, well they have internal R&D as well as guys who are explicitly R&D15:31
kanzureoften there is information that is considered off-limits until you divulge something else15:31
delinquentmebut that doesn't tell me how much automation is in that process15:31
delinquentmetrue15:31
nmz787i'm not so good at social engineering i guess :P15:32
kanzure"i stalked you at the last 10 parties we mutually went to, therefore we are now friends"15:32
kanzure"what no way man, you don't remember me? shit, well akram remembers me.. ah akram is working for you?"15:32
kanzureand then i realize i'm talking to the wrong person15:32
kanzurebrownies pulled a trick on me a while back15:33
Lemminkainensocial engineering?15:33
kanzurethe company knew him as paul, but his name wasn't paul, so they asked me how i knew paul15:33
Lemminkainenjust be friendly15:33
kanzurei am not talking about social engineering15:33
Lemminkainensocial engineering is for spergtards who are trying to grow out of their neckbeard phase15:33
nmz787social stumbling15:33
Lemminkainenkanzure isn't nmz787 was15:33
kanzurebeing friendly is necessary but not sufficient- this is why wordsmithing is useful15:33
delinquentmeLemminkainen, I've not trimmed in a few days.15:34
nmz787months of growth for me15:34
delinquentmeother than PLA ... are there other known bio-compatible 3dprinter filaments?15:35
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delinquentmefrom the (little) research I've done ... the number of bio-compatible photopolymers is WAY more15:35
entelechiosbe gregarious15:36
nmz787sucrose15:36
nmz787sugar glass15:37
nmz787highly biodegradable15:37
juri_i wonder how i'd print that. :/15:39
nmz787jmil posted a howto15:39
Lemminkainenbtw, I submit that there is a respectful difference between a sperglord and a spergtard15:39
nmz787that's too much deutcsch for me to comprehend15:39
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Lemminkainenwir können etwas genauer sprechen, wenn du das willst15:40
nmz787du, du hast, du has mich15:40
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nmz787ein zwei dright veir have another glass of bier!15:41
Lemminkainenich haße dich nicht15:41
delinquentmeIm freaking out in my head right now15:42
delinquentmecaffeine oh how I missed yew15:42
juri_oh god, where is my coffee cup!15:42
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nmz787i got an espresso machine at goodwill a few months ago15:43
nmz787it is being loved well15:43
nmz787along with raw grass-fed milk foamed15:43
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Lemminkainenwe need to make algae lactate interesting casein micellar complexes so that we can make milk more interesting15:53
Lemminkainenadd in some BCAAs and omega-3 PUFAs and get rid of that pesky lactose15:54
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bkeroWhere did poppingtonic go? :(17:46
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FourFire"18:20
FourFire<juri_> "humanityplus is doomed, because php programmers suck. obviously."" I thought it was just php which sucked18:20
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jrayhawkhumanityplus is the next facebook, because php18:40
kanzureyour powers of reasoning fascinate me18:41
kanzuremostly they confuse me18:41
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juri_reasoning is completely optional.18:55
delinquentmehttp://www.sciencedaily.com/releases/2012/10/121002150031.htm18:58
delinquentmebullshit?18:58
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Dantespeakshahaha foools19:12
Dantespeaksoh sorry wroong chanell19:13
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